Extraction Technologies for Medicinal and Aromatic ... - Capacity4Dev

Extraction Technologies for Medicinal and Aromatic ... - Capacity4Dev Extraction Technologies for Medicinal and Aromatic ... - Capacity4Dev

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EXTRACTION TECHNOLOGIES FOR MEDICINAL AND AROMATIC PLANTS 8 Microdistillation,Thermomicrodistillation and Molecular Distillation Techniques Abstract V. G. Pangarkar Medicinal and aromatic plants (MAPs) have assumed considerable signifi cance in view of their special attributes. There are many compounds of great therapeutic value which can be obtained only from the plant kingdom. Most of the ingredients in such extracts and oils are large bulky molecules highly sensitive to processing conditions. The processes for such extractions have been mostly based on “recipes”. In the recent past, signifi cant advances have been made in the unit operations which are part of the recipe-based processes. It is imperative that these advances, which are essentially aimed at achieving better yields at lower costs and are termed “process intensifi cation”, are incorporated into the processing of MAPs. This paper introduces the theme of process intensifi cation as applied to the processing of MAPs and presents an overview of several new technologies which allow rapid, cost-effective extraction. The application of such innovative technologies can yield signifi cant benefi ts in terms of the quality of the product and its yield per unit weight of the plant material processed. Recovery of dissolved essential oil components from steam distillation condensates is also addressed and the two available techniques are discussed in detail. 8.1 Introduction Phytochemicals derived from medicinal and aromatic plants (MAPs) have been important to humans for centuries. Before the advent of modern synthetic chemistry, many aroma and fl avor chemicals were derived from sources of natural origin such as fl owers, roots and stems. The contemporary system of allopathic medicine, which has gained tremendous importance in the treatment of various diseases, is mainly based on active pharmaceutical compounds made synthetically. However, in recent years increasing attention has been paid to the traditional systems of treatments followed in Asia and Africa. The variety of medicinal plants and their constituents are being discovered only recently. There are many compounds of great therapeutic value which can be obtained only from the plant kingdom. Thus, vincristine, perhaps better known as the chemotherapy agent Oncovin, is only synthesized in the periwinkle plant Catharanthus roseus, and the sole source of the compound is this plant species. There are many other compounds which are equally valuable in other sectors such as food fl avors, fragrances and cosmetics. The processing of MAPs for obtaining the required extracts and oils has been based on traditionally established “recipes”. Most of the ingredients in such extracts and oils are large bulky molecules highly sensitive to processing conditions. Generally, relatively mild conditions are used in such processes to protect the integrity of the valuable components. The 129

EXTRACTION TECHNOLOGIES FOR MEDICINAL AND AROMATIC PLANTS<br />

8 Microdistillation,Thermomicrodistillation<br />

<strong>and</strong> Molecular Distillation Techniques<br />

Abstract<br />

V. G. Pangarkar<br />

<strong>Medicinal</strong> <strong>and</strong> aromatic plants (MAPs) have assumed considerable signifi cance in view<br />

of their special attributes. There are many compounds of great therapeutic value which<br />

can be obtained only from the plant kingdom. Most of the ingredients in such extracts<br />

<strong>and</strong> oils are large bulky molecules highly sensitive to processing conditions. The processes<br />

<strong>for</strong> such extractions have been mostly based on “recipes”. In the recent past,<br />

signifi cant advances have been made in the unit operations which are part of the recipe-based<br />

processes. It is imperative that these advances, which are essentially aimed<br />

at achieving better yields at lower costs <strong>and</strong> are termed “process intensifi cation”, are<br />

incorporated into the processing of MAPs. This paper introduces the theme of process<br />

intensifi cation as applied to the processing of MAPs <strong>and</strong> presents an overview of<br />

several new technologies which allow rapid, cost-effective extraction. The application of<br />

such innovative technologies can yield signifi cant benefi ts in terms of the quality of the<br />

product <strong>and</strong> its yield per unit weight of the plant material processed. Recovery of dissolved<br />

essential oil components from steam distillation condensates is also addressed<br />

<strong>and</strong> the two available techniques are discussed in detail.<br />

8.1 Introduction<br />

Phytochemicals derived from medicinal <strong>and</strong> aromatic plants<br />

(MAPs) have been important to humans <strong>for</strong> centuries. Be<strong>for</strong>e the advent<br />

of modern synthetic chemistry, many aroma <strong>and</strong> fl avor chemicals were derived<br />

from sources of natural origin such as fl owers, roots <strong>and</strong> stems. The<br />

contemporary system of allopathic medicine, which has gained tremendous<br />

importance in the treatment of various diseases, is mainly based on active<br />

pharmaceutical compounds made synthetically. However, in recent years increasing<br />

attention has been paid to the traditional systems of treatments<br />

followed in Asia <strong>and</strong> Africa. The variety of medicinal plants <strong>and</strong> their constituents<br />

are being discovered only recently. There are many compounds of<br />

great therapeutic value which can be obtained only from the plant kingdom.<br />

Thus, vincristine, perhaps better known as the chemotherapy agent Oncovin,<br />

is only synthesized in the periwinkle plant Catharanthus roseus, <strong>and</strong> the<br />

sole source of the compound is this plant species. There are many other<br />

compounds which are equally valuable in other sectors such as food fl avors,<br />

fragrances <strong>and</strong> cosmetics.<br />

The processing of MAPs <strong>for</strong> obtaining the required extracts <strong>and</strong><br />

oils has been based on traditionally established “recipes”. Most of the ingredients<br />

in such extracts <strong>and</strong> oils are large bulky molecules highly sensitive<br />

to processing conditions. Generally, relatively mild conditions are used<br />

in such processes to protect the integrity of the valuable components. The<br />

129

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