Drug Dosing in Renal Insufficiency - Philippine College of Physicians
Drug Dosing in Renal Insufficiency - Philippine College of Physicians
Drug Dosing in Renal Insufficiency - Philippine College of Physicians
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Bioavailability <strong>in</strong> CKD<br />
• <strong>Drug</strong> absorption<br />
Absolute bioavailability rarely altered<br />
There • Reduced: is no quantitative furosemide, p<strong>in</strong>dolol strategy to predict<br />
changes • Increased: for one Beta drug blockers, based dihydrocode<strong>in</strong>e, on data from<br />
dextropropoxyphene<br />
another <strong>in</strong> the same class<br />
Alterations <strong>in</strong> peak concentration (C max ) and<br />
time at which peak concentration is atta<strong>in</strong>ed<br />
(T max )
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