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Drug Dosing in Renal Insufficiency - Philippine College of Physicians

Drug Dosing in Renal Insufficiency - Philippine College of Physicians

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<strong>Drug</strong> dos<strong>in</strong>g considerations for CKD<br />

• <strong>Drug</strong> dos<strong>in</strong>g recommendations may be different<br />

from orig<strong>in</strong>al pharmacok<strong>in</strong>etic study due to<br />

variability <strong>in</strong> serum creat<strong>in</strong><strong>in</strong>e determ<strong>in</strong>ations<br />

• Use the most appropriate tool to assess kidney<br />

function<br />

• <strong>Drug</strong> dosages should be adjusted accord<strong>in</strong>g to<br />

FDA or EMA approved product label<strong>in</strong>g<br />

KDIGO 2011

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