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Presentatie - vzw farmaka asbl

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ACE-inhibitoren<br />

71. Danchin. Arch Intern Med 2006;166:787-96<br />

Design N/n Population Sd Interventions Outcomes Results<br />

MA N=7,<br />

n=33<br />

960<br />

- Evidence of<br />

CAD<br />

-High cv risk<br />

- No cardiac<br />

failure or left<br />

ventricle<br />

dysfunction<br />

-80% male<br />

-39 to 70%<br />

previous MI<br />

4.4y -ACE-inhibitor<br />

(enalapril,<br />

perindopril,<br />

quinapril,<br />

ramipril or<br />

trandolapril)<br />

-placebo<br />

All cause death OR= 0.86 (95%CI 0.79 to 0.93)<br />

Cardiovascular death OR= 0.81 (95%CI 0.73 to 0.90)<br />

MI OR= 0.82 (95%CI 0.75 to 0.89)<br />

Stroke OR= 0.77 (95%CI 0.66 to 0.88)<br />

www.<strong>farmaka</strong>.be<br />

Project<br />

Farmaka

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