Presentatie - vzw farmaka asbl

PTCA vs oefentherapie
37.Hambrecht. Percutaneous coronary angioplasty compared with exercise training in patients with stable coronary artery
disease. Circulation 2004;109:1371-8
Design N/n Population Sd Interventions Outcomes Results
RCT N=101 -Class I to III angina pectoris
-100% male
-≤ 70 years
-Stable coronary artery disease
(coronary angiography)
-40-50% previous MI
-Exclusion: recent MI, important left
main coronary artery or left anterior
descending stenosis, reduced left
ventricular function, smoking,
insulin dependent diabetes
12 m -Exercise training
(20 minutes of
becycle ergometry
per day + 60
minute group
training session of
aerobic exercise)
-PCI with stent
Event-free
survival*
Amelioration
in angina
class
Exercise
parameters
88% vs 70% (PCI);
p=0.023
No difference
Better in exercise group
Both + medical
treatment
Event= death of cardiac cause, stroke, resuscitation after cardiac arrest, CABG, angioplasty and worsening angina with
objective evidence that resulted in hospitalization.
Legend
_ _ _ _ : exercise group
______: PCI
months