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Presentatie - vzw farmaka asbl

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CABG vs PTCA<br />

Bravata. Systematic review: The comparative effectiveness of PCI and CABG. Ann Intern Med 2007;147:703-16<br />

Design N/n Population Sd Interventions Outcomes Results<br />

MA N=23,<br />

n=5019<br />

RCT DATA<br />

Survival within 30 d -98.9% (PCI) vs 98.2%<br />

-Coronary<br />

artery disease<br />

-40% previous<br />

MI<br />

-Few had heart<br />

failure<br />

6 m<br />

to<br />

13y<br />

-PCI with or<br />

without stent<br />

-CABG<br />

-Only 1 trial<br />

used drugeluting<br />

stent<br />

Procedure related<br />

stroke<br />

Mortality at 1y<br />

Mortality at 5y<br />

Angina relief at 1 to<br />

5 y<br />

Repeated<br />

revascularization<br />

-ARD=0.2% (95%95%CI –0.3 to 0.6%)<br />

-1.2% % (CABG) vs 0.6%<br />

-ARD= 0.6% (95%95%CI 0.2 to 1%)<br />

-96.4 % (CABG) vs 96.5% ; NS<br />

-90.7 % (CABG) vs 89.7% ; NS<br />

-At 1 y: 84 % (CABG) vs 75%<br />

-At 5 y: 84 % (CABG) vs 79%<br />

ARD ranged from 5% to 8% in favour of<br />

CABG; p

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