Presentatie - vzw farmaka asbl
Presentatie - vzw farmaka asbl
Presentatie - vzw farmaka asbl
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CABG vs PTCA<br />
Bravata. Systematic review: The comparative effectiveness of PCI and CABG. Ann Intern Med 2007;147:703-16<br />
Design N/n Population Sd Interventions Outcomes Results<br />
MA N=23,<br />
n=5019<br />
RCT DATA<br />
Survival within 30 d -98.9% (PCI) vs 98.2%<br />
-Coronary<br />
artery disease<br />
-40% previous<br />
MI<br />
-Few had heart<br />
failure<br />
6 m<br />
to<br />
13y<br />
-PCI with or<br />
without stent<br />
-CABG<br />
-Only 1 trial<br />
used drugeluting<br />
stent<br />
Procedure related<br />
stroke<br />
Mortality at 1y<br />
Mortality at 5y<br />
Angina relief at 1 to<br />
5 y<br />
Repeated<br />
revascularization<br />
-ARD=0.2% (95%95%CI –0.3 to 0.6%)<br />
-1.2% % (CABG) vs 0.6%<br />
-ARD= 0.6% (95%95%CI 0.2 to 1%)<br />
-96.4 % (CABG) vs 96.5% ; NS<br />
-90.7 % (CABG) vs 89.7% ; NS<br />
-At 1 y: 84 % (CABG) vs 75%<br />
-At 5 y: 84 % (CABG) vs 79%<br />
ARD ranged from 5% to 8% in favour of<br />
CABG; p