Presentatie - vzw farmaka asbl
Presentatie - vzw farmaka asbl
Presentatie - vzw farmaka asbl
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β-blokkers<br />
17.Pepine. The atenolol silent ischemia study (ASIST). Circulation 1994;90:762-8<br />
Design n Population Sd Interventions Outcomes Results<br />
RCT,<br />
double<br />
blind<br />
306 -Silent ischemia or mild angina<br />
pectoris (coronary artery disease<br />
documented by previous myocardial<br />
infarction or coronarography)<br />
-Prior myocardial infarction: 40%<br />
-87% male<br />
-mean age: 65<br />
1 y -Atenolol 100<br />
mg/d<br />
-Placebo<br />
Any event<br />
(see table)<br />
- 11% (atenolol) vs 25%<br />
(placebo)<br />
- RR=0.44 (95%BI 0.26<br />
to 0.75)<br />
- NNT=7<br />
www.<strong>farmaka</strong>.be<br />
Project<br />
Farmaka
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