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Diabetes in pregnancy: are we providing the best care ... - HQIP

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of women after <strong>the</strong> fi rst trimester up to labour and delivery). This improved dur<strong>in</strong>g labour and delivery,<br />

with 79% of <strong>the</strong> 384 women deliver<strong>in</strong>g after 24 <strong>we</strong>eks hav<strong>in</strong>g a target range documented.<br />

When a target range was present dur<strong>in</strong>g <strong>pregnancy</strong>, <strong>the</strong>re was evidence that this had been communicated<br />

to <strong>the</strong> woman for only 48% of <strong>the</strong> 232 women <strong>in</strong> <strong>the</strong> fi rst trimester and 51% of <strong>the</strong> 239 women after <strong>the</strong><br />

fi rst trimester.<br />

9.4 <strong>Diabetes</strong> c<strong>are</strong> - monitor<strong>in</strong>g for diabetes complications<br />

In addition to achiev<strong>in</strong>g good glycaemic control dur<strong>in</strong>g <strong>pregnancy</strong>, women with diabetes also need ongo<strong>in</strong>g<br />

monitor<strong>in</strong>g and treatment for diabetes complications. There may be development of new ret<strong>in</strong>opathy<br />

or deterioration of pre-exist<strong>in</strong>g ret<strong>in</strong>opathy dur<strong>in</strong>g <strong>pregnancy</strong>, 8 and women should have a full ret<strong>in</strong>al<br />

assessment dur<strong>in</strong>g <strong>the</strong> fi rst trimester, 7 with prompt referral to an ophthalmologist if an abnormality is found.<br />

Women with diabetes nephropathy <strong>are</strong> at <strong>in</strong>creased risk of hypertensive disease of <strong>pregnancy</strong>, adverse<br />

fetal outcomes, and progressive deterioration of renal disease. 9-11 Enquiry panels <strong>we</strong>re not provided with<br />

an explicit standard of monitor<strong>in</strong>g for nephropathy, but <strong>we</strong>re provided with <strong>the</strong> guidance that appropriate<br />

monitor<strong>in</strong>g <strong>in</strong>cluded test<strong>in</strong>g for microalbum<strong>in</strong>uria (<strong>in</strong>cipient nephropathy), prote<strong>in</strong> dipstick test<strong>in</strong>g of ur<strong>in</strong>e<br />

or serum creat<strong>in</strong><strong>in</strong>e.<br />

9.4.1 Enquiry fi nd<strong>in</strong>gs<br />

Just over half of women (59%, 258/441), had a ret<strong>in</strong>al assessment documented dur<strong>in</strong>g <strong>the</strong> fi rst trimester<br />

or at <strong>the</strong> fi rst book<strong>in</strong>g visit. Only 55% of <strong>the</strong>se 258 assessments <strong>we</strong>re recorded to have been done through<br />

dilated pupils; for 40% of women, details about <strong>the</strong> ret<strong>in</strong>al assessment procedure <strong>we</strong>re not documented.<br />

Seventy eight percent (343/441) of women <strong>we</strong>re monitored for signs of nephropathy. Lack of monitor<strong>in</strong>g<br />

for nephropathy was associated with poor <strong>pregnancy</strong> outcome (OR 1.9, 95% CI 1.1 - 3.3, adjusted for<br />

maternal age and deprivation, see Chapter 6). Ho<strong>we</strong>ver, <strong>in</strong> <strong>the</strong> additional case-control analysis (see<br />

Appendices C, D and E), lack of monitor<strong>in</strong>g for nephropathy was associated only with fetal congenital<br />

anomaly and not with fetal or neonatal death after 20 <strong>we</strong>eks gestation, and is <strong>the</strong>refore unlikely to have<br />

been causative for poor <strong>pregnancy</strong> outcome. Nephropathy itself was not associated with poor <strong>pregnancy</strong><br />

outcome.<br />

Enquiry panels assessed that 60% (264/440) of women (72% of 204 cases and 58% of 204 controls)<br />

had suboptimal diabetes c<strong>are</strong> (c<strong>are</strong> o<strong>the</strong>r than glycaemic control management) dur<strong>in</strong>g <strong>pregnancy</strong>. These<br />

women <strong>we</strong>re more likely to have a poor <strong>pregnancy</strong> outcome (OR 1.7, 95% CI 1.1 - 2.6, adjusted for<br />

maternal age and deprivation, see Chapter 6). Additional case-control analysis (see Appendices C, D<br />

and E) sho<strong>we</strong>d an association with fetal or neonatal death from 20 <strong>we</strong>eks gestation and not with fetal<br />

congenital anomaly.<br />

9.4.2 Panel comments on suboptimal diabetes c<strong>are</strong> <strong>in</strong> <strong>pregnancy</strong><br />

Panels made 432 comments for 264 women about suboptimal diabetes c<strong>are</strong> <strong>in</strong> <strong>pregnancy</strong>, with <strong>the</strong><br />

majority of <strong>the</strong>se be<strong>in</strong>g concerns about suboptimal cl<strong>in</strong>ical practice (table 9.3).<br />

53

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