Power Point Slides Alcohol - Meagher Lab
Power Point Slides Alcohol - Meagher Lab
Power Point Slides Alcohol - Meagher Lab
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Physiological Aspects of <strong>Alcohol</strong><br />
Consumption<br />
! CNS Effects:<br />
! CNS depressant, slows the activity of the CNS, high doses<br />
can cause a reduction in tension & inhibitions, and impair<br />
judgment, motor control, and concentration.<br />
! Reduces anxiety by increasing the synaptic activity of<br />
GABA, an inhibitory neurotransmitter and by decreasing<br />
excitatory neurotransmission by both NMDA and non-NMDA<br />
receptors<br />
! The GABA-benzodiazepine receptor complex contains<br />
separate binding sites where alcohol, barbiturates &<br />
benzodiazepines bind to make it more sensitive to GABA.<br />
! Because GABA is an inhibitory neurotransmitter the final<br />
effect is to increase neural inhibition and decrease anxiety.
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