Power Point Slides Alcohol - Meagher Lab
Power Point Slides Alcohol - Meagher Lab Power Point Slides Alcohol - Meagher Lab
ADDICTION 39 Figure 4 Graphic representation of the sites on neurons at which drugs have been shown to produce morphological changes. (A) The most common type of neuron in the nucleus accumbens, a medium spiny neuron. Past experience with amphetamine, cocaine, or morphine has been shown to alter the number of dendritic branches seen radiating away from the cell body. (B) Magnified view of a dendrite that is studded with many dendritic spines. As indicated by the schematic drawing in (C ), dendritic spines are the site of synapses, and spines on the distal dendrites on medium spiny neurons receive both glutamate and dopamine inputs. Treatment with amphetamine, cocaine, or morphine also produces persistent changes in the number of dendritic spines on these neurons and therefore presumably in the number of synapses (Robinson & Kolb 1997, 1999a,b; Robinson et al. 2001). Camera lucida drawings (A and B) courtesy of Grazyna Gorny.
Alcoholism and Problem Drinking: Scope and Costs of the Problem ! >20% of Americans drink at levels that exceed government recommendations ! Alcohol consumption is linked to ! high blood pressure, stroke, cirrhosis of the liver, fetal alcohol syndrome, some cancers, cognitive impairments, 15% of health care costs = Etoh abuse treatment, underestimate of health costs ! Alcohol-related accidents: ! 1 in 2 Americans will be in one in their lifetimes ! 41% of traffic-related deaths related to alcohol ! 50% of all MVAs ! Economic: $42 billion annually in lost productivity, absenteeism
- Page 1 and 2: Health-Compromising Behaviors chara
- Page 3 and 4: Characteristics of Health-Compromis
- Page 5 and 6: What Is Substance Dependence? ! Phy
- Page 7 and 8: Addiction Theories (a) The opponent
- Page 9 and 10: Opponent Process Theory
- Page 11 and 12: B-process grows in strength with re
- Page 13 and 14: Koob’ Model (2004) Animal studies
- Page 15: Figure 3 Comparison of the critical
- Page 19 and 20: DSM-IV Definitions ! ALCOHOL ABUSE:
- Page 21 and 22: EPIDEMIOLOGY ! Stats: ! 1 out of 10
- Page 23 and 24: High School Alcohol Use 80% of 12th
- Page 25 and 26: Prevalence of alcohol use and depen
- Page 27 and 28: Epidemiology ! Personality factors
- Page 29 and 30: Physiological Aspects of Alcohol Co
- Page 31 and 32: How alcohol affects the brain
- Page 33 and 34: J-Shaped Curves J-shaped associatio
- Page 35 and 36: Alcohol and all cause mortality The
- Page 37 and 38: Alcohol:Incidence of Diabetes II Al
- Page 39 and 40: Alcoholism and Problem Drinking: Is
- Page 41 and 42: Heavy Drinking and Health ! Alcohol
- Page 43 and 44: Women More Vulnerable? Women are mo
- Page 45 and 46: Alcoholism and Problem Drinking: Or
- Page 47 and 48: Gene Environment Interactions ! Ear
- Page 49 and 50: Prevention of Alcohol Abuse ! Legal
- Page 51 and 52: Alcoholism and Problem Drinking: Dr
- Page 53 and 54: Alcoholism and Problem Drinking: Th
- Page 55 and 56: Alcoholism and Problem Drinking: Tr
- Page 57 and 58: Psychological Treatments ! Insight
- Page 59 and 60: Inpatient treatment? Evidence sugge
- Page 61 and 62: Motivational Enhancement Therapy 4)
- Page 63 and 64: Alcoholism and Problem Drinking: Pr
- Page 65 and 66: AA ! Dropout rate unknown? ! Compar
<strong>Alcohol</strong>ism and Problem Drinking:<br />
Scope and Costs of the Problem<br />
! >20% of Americans drink at levels that exceed<br />
government recommendations<br />
! <strong>Alcohol</strong> consumption is linked to<br />
! high blood pressure, stroke, cirrhosis of the liver,<br />
fetal alcohol syndrome, some cancers, cognitive<br />
impairments, 15% of health care costs = Etoh<br />
abuse treatment, underestimate of health costs<br />
! <strong>Alcohol</strong>-related accidents:<br />
! 1 in 2 Americans will be in one in their lifetimes<br />
! 41% of traffic-related deaths related to alcohol<br />
! 50% of all MVAs<br />
! Economic: $42 billion annually in lost productivity,<br />
absenteeism
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