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Compliance and regulatory requirements for the meat and poultry ...

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Zero tolerance vs 100 cfu/g as a safe level<br />

• Dose response still not clearly defined - Infectious dose remains<br />

problematic<br />

• susceptibility of individuals<br />

• variation in strain virulence<br />

• Current data suggest that greater than 1000 cfu/g may be needed to<br />

cause listeriosis<br />

• Epidemiology of disease is changing<br />

• > numbers elderly with underlying medical conditions<br />

• more sporadic cases, not large outbreaks

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