23.10.2014 Views

Burns injury - PACT - ESICM

Burns injury - PACT - ESICM

Burns injury - PACT - ESICM

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

performed in this setting. If prognosis appears poor and palliation seems to be the<br />

best choice after an overall evaluation, the decision to terminate active treatment<br />

should be made as early as possible in the treatment course.<br />

For further reading see the <strong>PACT</strong> modules on Ethics and Communication.<br />

Cole P, Stal D, Hollier L. Ethical considerations in burn management. J<br />

Craniofac Surg 2008; 19(4): 895–898. PMID 18650707<br />

Young AE. The Laing essay 1998: ethical issues in burn care. <strong>Burns</strong> 1999; 25(3):<br />

193–206. PMID 10323603<br />

Platt AJ, Phipps AR, Judkins K. Is there still a place for comfort care in severe<br />

burns? <strong>Burns</strong> 1998; 24(8): 754–756. PMID 9915678<br />

Burn care research<br />

Although the research activities have increased in the burn care community<br />

throughout the years, a significant portion of usual burn care practices still lack a<br />

strong scientific basis. Despite this, mortality has decreased significantly, length of<br />

stay has dramatically been shortened and long-term outcome assessed as health<br />

related quality of life has improved. However, mainstream burn care does still not<br />

fulfill the highest evidence-based medicine (EBM) criteria. At the same time, it is<br />

important to realise that a significant amount of knowledge used in burn care and<br />

other care specialties, especially trauma and critical care, are based on early<br />

experiences in the care of the burn injured. This applies especially to fluid therapy,<br />

knowledge on the trauma response and the complications in the post trauma care<br />

period and the nutritional support. Lately, important research within burn care has<br />

been conducted in the field of modification to the trauma response - such as<br />

pharmacological modulation of this specific trauma response.<br />

Within the burns specialty, the focus is now directed at improving research quality<br />

and there is a strong demand for more randomised controlled trials supporting<br />

present care and identifying better care strategies.<br />

http://www.elsevier.com/wps/find/journaldescription.cws_home/30394/description<br />

#description) and the journal of Burn Care Research<br />

http://journals.lww.com/burncareresearch/pages/default.aspx<br />

Herndon DN, Hart DW, Wolf SE, Chinkes DL, Wolfe RR. Reversal of catabolism<br />

by beta-blockade after severe burns. N Engl J Med 2001; 345(17): 1223–<br />

1229. PMID 11680441<br />

Herndon DN, Tompkins RG. Support of the metabolic response to burn <strong>injury</strong>.<br />

Lancet 2004; 363(9424): 1895–1902. PMID 15183630<br />

Jeschke MG, Kulp GA, Kraft R, Finnerty CC, Mlcak R, Lee JO, et al. Intensive<br />

insulin therapy in severely burned pediatric patients: a prospective<br />

randomized trial. Am J Respir Crit Care Med 2010; 182(3): 351–359. PMID<br />

20395554<br />

46

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!