Proton Pump Inhibitors - CME Conferences

Proton Pump Inhibitors - CME Conferences Proton Pump Inhibitors - CME Conferences

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6 th Annual Primary Care Spring Conference Thursday, April 12, 2012 Proton Pump Inhibitors • The most important recommendation with any PPI is to take it 30-60 minutes prior to a significant meal! • “Seventy percent of primary care physicians and 20% of gastroenterologists prescribe PPIs sub optimally, either at bedtime or unrelated to food intake, this is the most common cause of PPI failure.” • Gastroenterology 2008; 134: 1842-1860 PPI’s Benefits vs. Risk? • Potential risks include: • Community and hospital acquired pneumonia • Risk of nosocomial C. difficile infection • Risk of fractures including hip fracture • Risk of B12, calcium and magnesium deficiencies • Risk of acid rebound Wayne Weart, Pharm D Cost Effective Rx

6 th Annual Primary Care Spring Conference Thursday, April 12, 2012 Proton Pump Inhibitors • Omeprazole Generic Prilosec • 20mg caps $33.32/30 $195.99/30 • 40mg caps $195.00/30 $291.00/30 • Omeprazole OTC Generic Prilosec OTC • 20.6mg tabs $21.99/42 $24.99/42 • Lansoprazole Generic Prevacid • 15mg caps $99.99/30 $195.00/30 • 30mg caps $99.99/30 $183.25/30 • Lansoprazole OTC Prevacid 24 • 15mg caps $26.99/42 Drugstore.com 3-2012 Proton Pump Inhibitors • Pantoprazole Generic Protonix • 20mg tabs $15.99/30 $186.38/30 • 40mg tabs $15.99/30 $190.00/30 • Esomeprasole Nexium • 20mg caps $200.99/30 • 40mg caps $189.99/30 • Dexlansoprazole Dexilant • 30 and 60mg caps $149.99/30 • Rabeprazole Aciphex • 20mg tabs $249.99/30 Drugstore.com 3-2012 Wayne Weart, Pharm D Cost Effective Rx

6 th Annual Primary Care Spring Conference Thursday, April 12, 2012<br />

<strong>Proton</strong> <strong>Pump</strong> <strong>Inhibitors</strong><br />

• Omeprazole Generic<br />

Prilosec<br />

• 20mg caps $33.32/30 $195.99/30<br />

• 40mg caps $195.00/30 $291.00/30<br />

• Omeprazole OTC Generic Prilosec OTC<br />

• 20.6mg tabs $21.99/42 $24.99/42<br />

• Lansoprazole Generic Prevacid<br />

• 15mg caps $99.99/30 $195.00/30<br />

• 30mg caps $99.99/30 $183.25/30<br />

• Lansoprazole OTC Prevacid 24<br />

• 15mg caps $26.99/42<br />

Drugstore.com 3-2012<br />

<strong>Proton</strong> <strong>Pump</strong> <strong>Inhibitors</strong><br />

• Pantoprazole Generic <strong>Proton</strong>ix<br />

• 20mg tabs $15.99/30 $186.38/30<br />

• 40mg tabs $15.99/30 $190.00/30<br />

• Esomeprasole<br />

Nexium<br />

• 20mg caps $200.99/30<br />

• 40mg caps $189.99/30<br />

• Dexlansoprazole<br />

Dexilant<br />

• 30 and 60mg caps $149.99/30<br />

• Rabeprazole<br />

Aciphex<br />

• 20mg tabs $249.99/30<br />

Drugstore.com 3-2012<br />

Wayne Weart, Pharm D<br />

Cost Effective Rx

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