Proton Pump Inhibitors - CME Conferences
Proton Pump Inhibitors - CME Conferences
Proton Pump Inhibitors - CME Conferences
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6 th Annual Primary Care Spring Conference Thursday, April 12, 2012<br />
<strong>Proton</strong> <strong>Pump</strong> <strong>Inhibitors</strong><br />
• The most important recommendation<br />
with any PPI is to take it 30-60<br />
minutes prior to a significant meal!<br />
• “Seventy percent of primary care physicians<br />
and 20% of gastroenterologists prescribe PPIs<br />
sub optimally, either at bedtime or unrelated to<br />
food intake, this is the most common cause of<br />
PPI failure.”<br />
• Gastroenterology 2008; 134: 1842-1860<br />
PPI’s Benefits vs. Risk?<br />
• Potential risks include:<br />
• Community and hospital acquired pneumonia<br />
• Risk of nosocomial C. difficile infection<br />
• Risk of fractures including hip fracture<br />
• Risk of B12, calcium and magnesium<br />
deficiencies<br />
• Risk of acid rebound<br />
Wayne Weart, Pharm D<br />
Cost Effective Rx
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