Proton Pump Inhibitors - CME Conferences
Proton Pump Inhibitors - CME Conferences
Proton Pump Inhibitors - CME Conferences
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6 th Annual Primary Care Spring Conference Thursday, April 12, 2012<br />
American Academy of Neurology<br />
Consensus Statement<br />
“ Nonequivalence can have very serious<br />
effects. Decreased serum drug<br />
concentrations can cause breakthrough<br />
seizures, and increased concentrations<br />
can lead to toxicity……The overall cost<br />
to society of breakthrough seizures or<br />
drug toxicity may outweigh any<br />
economic incentive for mandating<br />
generic substitution”<br />
Neurology 1990;40:1647-1651<br />
FDA<br />
FDA Estimate of Savings<br />
Center for Drug Evaluation and Research<br />
Wayne Weart, Pharm D<br />
Cost Effective Rx