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European Resuscitation Council Guidelines for Resuscitation 2010 ...

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C.D. Deakin et al. / <strong>Resuscitation</strong> 81 (<strong>2010</strong>) 1305–1352 1309<br />

ing no difference in short- or long-term survival. 183,189,191,193–199<br />

in one study, survival of the event was lower when physicians<br />

were part of the resuscitation team. 199 Studies indirectly comparing<br />

resuscitation outcomes between physician-staffed and other<br />

systems are difficult to interpret because of the extremely high<br />

variability between systems, independent of physician-staffing. 200<br />

Although some studies have documented higher survival rates<br />

after cardiac arrest in EMS systems that include experienced<br />

physicians, 186,188,201–203 compared with those that rely on nonphysician<br />

providers, 201,202,204,205 other comparisons have found no<br />

difference in survival between systems using paramedics or physicians<br />

as part of the response. 206,207 Well-organised non-physician<br />

systems with highly trained paramedics have also reported high<br />

survival rates. 200 Given the inconsistent evidence, the inclusion or<br />

exclusion of physicians among prehospital personnel responding<br />

to cardiac arrests will depend largely on existing local policy.<br />

Termination of resuscitation rules<br />

One high-quality, prospective study has demonstrated that<br />

application of a ‘basic life support termination of resuscitation rule’<br />

is predictive of death when applied by defibrillation-only emergency<br />

medical technicians. 208 The rule recommends termination<br />

when there is no return of spontaneous circulation, no shocks are<br />

administered, and the arrest is not witnessed by EMS personnel. Of<br />

776 patients with cardiac arrest <strong>for</strong> whom the rule recommended<br />

termination, four survived [0.5% (95% CI 0.2–0.9)]. Implementation<br />

of the rule would reduce the transportation rate by almost two<br />

thirds. Four studies have shown external generalisability of this<br />

rule. 209–212<br />

Additional studies have shown associations with futility of certain<br />

variables such as no ROSC at scene; non-shockable rhythm;<br />

unwitnessed arrest; no bystander CPR, call response time and<br />

patient demographics. 213–218<br />

Two in-hospital studies and one emergency department study<br />

showed that the reliability of termination of resuscitation rules is<br />

limited in these settings. 219–221<br />

Prospectively validated termination of resuscitation rules such<br />

as the ‘basic life support termination of resuscitation rule’ can be<br />

used to guide termination of prehospital CPR in adults; however,<br />

these must be validated in an emergency medical services system<br />

similar to the one in which implementation is proposed. Other rules<br />

<strong>for</strong> various provider levels, including in-hospital providers, may be<br />

helpful to reduce variability in decision-making; however, rules<br />

should be prospectively validated prior to implementation.<br />

CPR versus defibrillation first<br />

There is evidence that per<strong>for</strong>ming chest compressions while<br />

retrieving and charging a defibrillator improves the probability of<br />

survival. 222 EMS personnel should provide good-quality CPR while<br />

a defibrillator is retrieved, applied and charged, but routine delivery<br />

of a pre-specified period of CPR (e.g., 2 or 3 min) be<strong>for</strong>e rhythm analysis<br />

and a shock is delivered is not recommended. Some emergency<br />

medical services have already fully implemented a pre-specified<br />

period of chest compressions be<strong>for</strong>e defibrillation; given the lack<br />

of convincing data either supporting or refuting this strategy, it is<br />

reasonable <strong>for</strong> them to continue this practice (see Section 3). 223<br />

4c In-hospital resuscitation<br />

After in-hospital cardiac arrest, the division between basic life<br />

support and advanced life support is arbitrary; in practice, the<br />

resuscitation process is a continuum and is based on common sense.<br />

The public expect that clinical staff can undertake cardiopulmonary<br />

resuscitation (CPR). For all in-hospital cardiac arrests, ensure that:<br />

• cardiorespiratory arrest is recognised immediately;<br />

• help is summoned using a standard telephone number;<br />

• CPR is started immediately using airway adjuncts, e.g., a pocket<br />

mask and, if indicated, defibrillation attempted as rapidly as possible<br />

and certainly within 3 min.<br />

The exact sequence of actions after in-hospital cardiac arrest<br />

will depend on many factors, including:<br />

• location (clinical/non-clinical area; monitored/unmonitored<br />

area);<br />

• training of the first responders;<br />

• number of responders;<br />

• equipment available;<br />

• hospital response system to cardiac arrest and medical emergencies<br />

(e.g., MET, RRT).<br />

Location<br />

Patients who have monitored arrests are usually diagnosed<br />

rapidly. Ward patients may have had a period of deterioration and<br />

an unwitnessed arrest. 6,8 Ideally, all patients who are at high risk<br />

of cardiac arrest should be cared <strong>for</strong> in a monitored area where<br />

facilities <strong>for</strong> immediate resuscitation are available.<br />

Training of first responders<br />

All healthcare professionals should be able to recognise cardiac<br />

arrest, call <strong>for</strong> help and start CPR. Staff should do what they have<br />

been trained to do. For example, staff in critical care and emergency<br />

medicine will have more advanced resuscitation skills than<br />

staff who are not involved regularly in resuscitation in their normal<br />

clinical role. Hospital staff who attend a cardiac arrest may<br />

have different levels of skill to manage the airway, breathing and<br />

circulation. Rescuers must undertake only the skills in which they<br />

are trained and competent.<br />

Number of responders<br />

The single responder must ensure that help is coming. If other<br />

staff are nearby, several actions can be undertaken simultaneously.<br />

Equipment available<br />

All clinical areas should have immediate access to resuscitation<br />

equipment and drugs to facilitate rapid resuscitation of the patient<br />

in cardiopulmonary arrest. Ideally, the equipment used <strong>for</strong> CPR<br />

(including defibrillators) and the layout of equipment and drugs<br />

should be standardised throughout the hospital. 224,225<br />

<strong>Resuscitation</strong> team<br />

The resuscitation team may take the <strong>for</strong>m of a traditional cardiac<br />

arrest team, which is called only when cardiac arrest is recognised.<br />

Alternatively, hospitals may have strategies to recognise patients<br />

at risk of cardiac arrest and summon a team (e.g., MET or RRT)<br />

be<strong>for</strong>e cardiac arrest occurs. The term ‘resuscitation team’ reflects<br />

the range of response teams. In hospital cardiac arrests are rarely<br />

sudden or unexpected. A strategy of recognising patients at risk of<br />

cardiac arrest may enable some of these arrests to be prevented, or<br />

may prevent futile resuscitation attempts in those who are unlikely<br />

to benefit from CPR.

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