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Santosh K. Katiyar, Ph.D. - University of Alabama at Birmingham

Santosh K. Katiyar, Ph.D. - University of Alabama at Birmingham

Santosh K. Katiyar, Ph.D. - University of Alabama at Birmingham

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Multi-stage carcinogenesis model leading to the development <strong>of</strong><br />

papillomas and subsequent progression to carcinomas.<br />

Initi<strong>at</strong>ion<br />

Promotion<br />

Rel<strong>at</strong>ive Tumor Yield<br />

Papilloma<br />

Carcinoma<br />

+ +<br />

_ _<br />

++ + ++<br />

+ ++ + +<br />

++ +<br />

_<br />

+<br />

_<br />

_ _<br />

Applic<strong>at</strong>ion <strong>of</strong> large dose <strong>of</strong><br />

DMBA<br />

Applic<strong>at</strong>ion <strong>of</strong> small dose <strong>of</strong><br />

DMBA<br />

Applic<strong>at</strong>ion <strong>of</strong><br />

TPA

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