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Santosh K. Katiyar, Ph.D. - University of Alabama at Birmingham

Santosh K. Katiyar, Ph.D. - University of Alabama at Birmingham

Santosh K. Katiyar, Ph.D. - University of Alabama at Birmingham

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• EGCG prevents UVB-induced immune<br />

suppression, and UVB-induced immune<br />

suppression is considered as a risk factor for the<br />

development <strong>of</strong> non-melanoma skin cancer.<br />

• We have also shown th<strong>at</strong> inhibition <strong>of</strong> UVBinduced<br />

immunosuppression in mice by EGCG is<br />

associ<strong>at</strong>ed with the increased levels <strong>of</strong> IL-12.<br />

Carcinogenesis, 20: 2117-2124, 1999.<br />

• IL-12 has anti-tumor activity and DNA repair<br />

ability. Therefore,

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