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Strychnos 1990 - 2004 - Crops for the Future

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Author<br />

Title<br />

Year<br />

Source title<br />

Reference<br />

Chen, W. S., L. L. Liu, X. Li, L. W. Li, S. G. Ji, G. Q. Zhang and Y. F. Chai<br />

Separation and determination of strychnine and brucine in <strong>Strychnos</strong> nux vomica<br />

2000<br />

Biomedical Chromatography<br />

14(8): 541-543<br />

Abstract<br />

A capillary zone electrophoresis method was developed <strong>for</strong> <strong>the</strong> separation and determination of<br />

strychnine and brucine in <strong>Strychnos</strong> nux-vomica L. and its preparation. The factors that could affect<br />

<strong>the</strong> separation were studied, such as <strong>the</strong> types and concentrations of electrolytes, pH, ionic strength<br />

and organic modifier. The optimum running buffer was 20 mmol/L of ammonium acetate containing<br />

0.2 mol/L of glacial acetic acid (pH 3.64). The applied voltage was 25 kV and <strong>the</strong> wavelength of <strong>the</strong><br />

UV detector was set at 214 nm. The established method with dopamine hydrochloride as internal<br />

standard was linear in <strong>the</strong> range of 5-100 mug/mL <strong>for</strong> both strychnine and brucine. The recovery was<br />

102.96% <strong>for</strong> strychnine and 98.56% <strong>for</strong> brucine. The extracts of <strong>Strychnos</strong> nux-vomica and its<br />

preparation could be directly injected <strong>for</strong> analysis. Copyright (C) 2000 John Wiley & Sons, Ltd.<br />

Author<br />

Title<br />

Year<br />

Source title<br />

Reference<br />

Ergun, Y., N. Bayraktar, S. Patir and G. Okay<br />

Intermediates <strong>for</strong> <strong>the</strong> syn<strong>the</strong>sis of indole alkaloids. Syn<strong>the</strong>sis of tetrahydrocarbazo<br />

2000<br />

Journal of Heterocyclic Chemistry<br />

37(1): 11-14<br />

Abstract<br />

The syn<strong>the</strong>sis of new precursors 8 and 15 <strong>for</strong> <strong>the</strong> syn<strong>the</strong>sis of tetracyclic indole alkaloids were<br />

described. Many new intermediates 4-7 and 9-14 have also been syn<strong>the</strong>sized.<br />

Author<br />

Title<br />

Year<br />

Source title<br />

Reference<br />

Abstract<br />

Frederich, M., M. C. De Pauw, G. Liabres, M. Tits, M. P. Hayette, V. Brandt, J. P<br />

New antimalarial and cytotoxic sungucine derivatives from <strong>Strychnos</strong> icaja roots<br />

2000<br />

Planta Medica<br />

66(3): 262-269<br />

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