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PROCALCITONIN Evaluation & Use In Victoria, BC

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PHYSIOLOGY-2<br />

Stimulated by bacterial Products on TLRs<br />

Part of innate immunity - uncertain function<br />

Reports of added PCT worsening inflammation<br />

Reports of removal of PCT decreasing inflammation<br />

<strong>In</strong>creased levels detectable within 6h<br />

Half life 30h<br />

Without stimulus, drops 30-50% within 24h<br />

Disposal – <strong>In</strong>ternal degradation, renal clearance<br />

is minor

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