PROCALCITONIN Evaluation & Use In Victoria, BC
PROCALCITONIN Evaluation & Use In Victoria, BC
PROCALCITONIN Evaluation & Use In Victoria, BC
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PHYSIOLOGY-2<br />
Stimulated by bacterial Products on TLRs<br />
Part of innate immunity - uncertain function<br />
Reports of added PCT worsening inflammation<br />
Reports of removal of PCT decreasing inflammation<br />
<strong>In</strong>creased levels detectable within 6h<br />
Half life 30h<br />
Without stimulus, drops 30-50% within 24h<br />
Disposal – <strong>In</strong>ternal degradation, renal clearance<br />
is minor