PROCALCITONIN Evaluation & Use In Victoria, BC

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PCT CAVEATS Not for guiding antibiotic treatment in : <strong>In</strong>fections: endocarditis, osteomyelitis, CNS infs, deep-infections, Pseudomonas pneumonia. Organisms: Listeria, Legionella, PCP, Mycobacteria Immunosuppressed patients
IMPLEMENTATION 3 month evaluation in SI - ICUs & ERs Reference <strong>In</strong>terval Adults 0.25-0.50 – Bacterial infection likely – rpt 6-24h >0.50-2.0 – Bacterial infection very likely . Moderate risk for sepsis >2.0 – Bacterial infection very likely. High risk for sepsis
Page 1 and 2: PROCALCITONIN Evaluation & Use In V
Page 3 and 4: SIRS & SEPSIS: SIRS Systemic Infla
Page 5 and 6: PHYSIOLOGY-1 PCT is the precursor
Page 7 and 8: THYROID C-CELL
Page 9 and 10: PHYSIOLOGY-2 Stimulated by bacteri
Page 11 and 12: CONTENTS SIRS, SEPSIS, PCT HISTORY
Page 13 and 14: INITIAL EVALUATION Objectives: Eva
Page 15 and 16: 90 80 y = 0.8418x - 0.4055 R² = 0.
Page 19 and 20: INITIAL PCT AND CRP RESULTS CULTURE
Page 21 and 22: PCT v OTHER MKRS SOFA = Sequential
Page 23 and 24: THE VALUE OF PCT Decision to treat
Page 25: OTHER POSSIBLE VALUE Monitoring pat
Page 30 and 31: ACCEPTANCE OF TEST Generally good
Page 32 and 33: FALSE RESULTS False negatives not
Page 36 and 37: PCT v HRS AFTER BIRTH Brahms’ dat
Page 38 and 39: OTHER USES FOR PCT Prediction of r
Page 40: KEY REFERENCES 1. Mirjam Christ-Cra

PROCALCITONIN Evaluation & Use In Victoria, BC

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