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EXHIBITOR DESCRIPTIONS<br />

EXHIBITOR DESCRIPTIONS<br />

SIGMA Life Science 1306<br />

3050 Spruce Street<br />

St. Louis, MO 63103<br />

United States<br />

Tel: 314.771.5765<br />

Toll Free: 800.325.3010<br />

Fax: 800.325.5052<br />

E-mail: kristen.bettinger@sial.com<br />

Web site: http://sageresearchmodels.com<br />

Simulations Plus, Inc. 1258<br />

42505 10th Street West<br />

Lancaster, CA 93534-7059<br />

United States<br />

Tel: 661.723.7723<br />

Toll Free: 888.266.9294<br />

Fax: 661.723.5524<br />

E-mail: john.dibella@simulations-plus.com<br />

Web site: http://www.simulations-plus.com<br />

SIGMA Life Science offers a wide portfolio of innovative<br />

technologies, products and services spanning cell biology, protein<br />

assays, genomics, functional genomics, biomolecules, epigenetics,<br />

stem cell research and transgenic animal models. Through continued<br />

investment in innovation and quality we are the leading destination<br />

for life science researchers to access deep biological information and<br />

market leading products that improve the quality of life.<br />

Product Categories: Animal Models, Biomarkers, Biotechnology<br />

Products, Cells/Tissue, Transgenic Models<br />

The ADMET Predictor Toxicity Module provides in silico<br />

predictions for several toxicities: MRTD, hERG, rat estrogen<br />

receptor (RBA), rat and mouse carcinogenicity (TD50), ten<br />

salmonella mutagenicities, fathead minnow LD50, aquatic toxicity<br />

(tetrahymena pyriformis PICG50), and hepatotoxicity. GastroPlus is<br />

used to estimate dose levels for toxicity studies in animals, using the<br />

industry’s most advanced PBPK capability. MedChem Studio can<br />

provide insight into how molecular features affect toxicities.<br />

Product Categories: ADME (Absorption/Distribution/Metabolism/<br />

Excretion), Consulting Services, Modeling Products/Services,<br />

Pharmacokinetics, QSAR (Quantitative Structure Activity<br />

Relationship) Modeling/Analysis<br />

SimuGen 1026<br />

83 Victoria Street<br />

London, SW1H 0HW<br />

United Kingdom<br />

Tel: +603 2727 3306<br />

E-mail: matt.vanleeuwen@simugen-global.com<br />

Web site: http://www.simugen-global.com<br />

✯ 2011 <strong>Annual</strong> <strong>Meeting</strong> Silver Sponsor<br />

SimuGen (www.simugen-global.com) is an international drug<br />

discovery pharmacogenomics company with strengths covering<br />

functional genomics, clinical medicine and mathematics. The<br />

company models molecular and high content phenotypes<br />

(biomarkers) in human cell cultures to predict how humans will<br />

respond to new drugs particularly the side effects they suffer. The<br />

company implements its models to analyse in vitro data as software<br />

(www.ht-stream.com) targeting the current innovation stagnation in<br />

drug discovery.<br />

Product Categories: Acute Toxicology Services/Testing, Genomics<br />

Research/Testing, Pharmaceutical Product Safety/Toxicology,<br />

Safety Assessment, Toxicogenomics<br />

Sinclair Research Center LLC 1346<br />

P.O. Box 658<br />

Columbia, MO 65205<br />

United States<br />

Tel: 573.387.4400<br />

Fax: 573.387.4404<br />

E-mail: info@sinclairresearch.com<br />

Web site: http://www.sinclairresearch.com<br />

Toxicology: All species, acute/chronic, exploratory tox/efficacy<br />

and GLP IND enabling studies, safety pharmacology. Specialties:<br />

TK/PK/ADME, NHP, dermal, ocular, juvenile tox, 10993<br />

Biocomp. Surgical Services: Cardiovascular, orthopedic, wound<br />

healing, VAPs/cannulae. Animal Models: Type I/II diabetes,<br />

obesity, atherosclerosis, osteoporosis, transdermal, melanoma,<br />

cardiovascular. Miniature Swine Sales: White hairless Yucatan,<br />

Sinclair, Yucatan/Micro Yucatan, Hanford.<br />

Product Categories: Acute Toxicology Services/Testing, Animal<br />

Models, CRO—Contract Research Organization, Dermal<br />

Research/Testing, GLP—Good Laboratory Practice Services,<br />

Medical Devices/Testing, Neonatal/Pediatric Studies, Ophthalmic<br />

Research/Testing, Pharmacoki<br />

Products and Services 365 days of the year—Visit <strong>ToxExpo</strong>.com<br />

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