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A Brief History of Microbiology Learning Outcomes

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Slide 23<br />

Slide 24<br />

Edward Jenner<br />

• 1796<br />

• Observed prevalence <strong>of</strong><br />

smallpox lower in rural<br />

than urban areas<br />

• Milkmaid with cow pox<br />

blisters didn’t develop<br />

smallpox<br />

• Scratched pus from<br />

cowpox blister into arm<br />

<strong>of</strong> ‘volunteer’<br />

• Exposed volunteer to<br />

smallpox to prove<br />

immunity<br />

• Vacca = cow<br />

• Vaccination<br />

Alexander<br />

Fleming<br />

• 1928: Culture plates <strong>of</strong><br />

Staphylococcus aureus<br />

“contaminated” by mold<br />

• Noticed halo <strong>of</strong><br />

inhibition <strong>of</strong> bacterial<br />

growth<br />

• Mold Penicillium<br />

notatum<br />

• Inhibition due to<br />

Penicillin<br />

Biol 240 S06 23<br />

Biol 240 S06 24<br />

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