BEVACIZUMAB EFFECT ON TOPOTECAN PHARMACOKINETICS ...
BEVACIZUMAB EFFECT ON TOPOTECAN PHARMACOKINETICS ...
BEVACIZUMAB EFFECT ON TOPOTECAN PHARMACOKINETICS ...
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Figure 6. Representative plasma and tumor disposition of TPT with/without<br />
MDBT in mice bearing Rh30 RMS xenograft<br />
Representative unbound TPT concentration-time plots in tumor ECF ( ) and plasma ( )<br />
in Rh30 rhabdomyosarcoma xenograft mice were shown above. Compared to the three<br />
compartmental PK model, the modified multi-compartmental PK model significantly<br />
(p