BEVACIZUMAB EFFECT ON TOPOTECAN PHARMACOKINETICS ...
BEVACIZUMAB EFFECT ON TOPOTECAN PHARMACOKINETICS ...
BEVACIZUMAB EFFECT ON TOPOTECAN PHARMACOKINETICS ...
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
LIST OF ABBREVIATI<strong>ON</strong>S<br />
ABC<br />
ATP-binding cassette<br />
ADA<br />
Anti-drug antibodies<br />
ARMS<br />
Alveolar rhabdomyosarcoma<br />
AUC<br />
Area under concentration-time<br />
AUCt<br />
Area under concentration-time in tumor<br />
AUCp<br />
Area under concentration-time in plasma<br />
BCRP<br />
Breast cancer resistance protein<br />
BEV<br />
Bevacizumab<br />
bFGF<br />
Basic fibroblast growth factor<br />
COG<br />
Children’s oncology group<br />
CGH<br />
Comparative genomic hybridization<br />
CPT-11<br />
Irinotecan<br />
CSF<br />
Cerebrospinal fluid<br />
CYP<br />
Cytochrome p450<br />
ECF<br />
Extracellular fluid<br />
ECM<br />
Extracellular matrix<br />
ERMS<br />
Embryonal rhabdomyosarcoma<br />
HPLC<br />
High-performance liquid chromatography<br />
IFP<br />
Interstitial fluid pressure<br />
IIV<br />
Inter-individual variability<br />
IRS<br />
Intergroup rhabdomyosarcoma study group<br />
IC<br />
Intracerebral<br />
IP<br />
Intraperitoneally<br />
IV<br />
Intravenously<br />
MDBT<br />
Multiple doses of bevacizumab treatment<br />
MLEM<br />
Maximal likelihood expectation maximization<br />
MMPs<br />
Matrix metalloproteinases<br />
MMP-2<br />
Matrix metalloproteinase-2<br />
MT1-MMP Membrane type 1 metalloproteinase<br />
MVD<br />
Microvessel density<br />
NMR<br />
Nuclear magnetic resonance<br />
PBS<br />
Phosphate buffered saline<br />
PD<br />
Pharmacodynamic<br />
PDGF<br />
Platelet-derived growth factor<br />
PET<br />
Positron emission tomography<br />
PK<br />
Pharmacokinetics<br />
PTX<br />
Paclitaxel<br />
P-gp P-glycoprotein 1<br />
QAR<br />
Quantitative autoradiography<br />
RD<br />
Embryonal rhabdomyosarcoma cell line<br />
RH30<br />
Alveolar rhabdomyosarcoma cell line<br />
RMS<br />
Rhabdomyosarcoma<br />
SD<br />
Standard deviation<br />
x