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Where Behavior and Brain Intersect

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TEL AVIV UNIVERSITY REVIEW<br />

Summer 2010<br />

emerging technology that can be<br />

morphed into a threat. “A particularly<br />

interesting trend is ‘swarm robotics,’<br />

whereby, inspired by the behavior of<br />

swarms in nature, large numbers of<br />

robots are programmed to coordinate<br />

their activities with one another,” says<br />

Dr. Hauptman, who notes that robots<br />

could become a st<strong>and</strong>ard terrorist<br />

weapon, even replacing the suicide<br />

bomber.<br />

In the coming months, FESTOS<br />

will survey international experts in<br />

the fields of interest in order to identify<br />

areas of concern <strong>and</strong> create a model<br />

for monitoring scientific advancements.<br />

One long-term objective of<br />

the program is to produce a database<br />

of ongoing scientific developments<br />

<strong>and</strong> potential future risks. According<br />

to Dr. Sharan, “this database will not<br />

only act as an ‘early warning system’<br />

which identifies potential threats to<br />

society, but it will also help assess preventative<br />

measures that might keep<br />

valuable information from those who<br />

seek to harm society, aiding in the<br />

creation of future EU security policy.”<br />

Targeting<br />

Cancer Cells<br />

TAU researchers uncover<br />

cancer-killing properties of an<br />

anti-stroke drug<br />

TAU scientists have tapped into a promising<br />

new cancer treatment through research<br />

involving a decade-old drug. Prof. Malka<br />

Cohen-Armon of TAU’s Sackler School of<br />

Medicine <strong>and</strong> her team of researchers have discovered<br />

a new use for a compound that was<br />

originally developed to prevent nerve cells<br />

from sustaining damage from stroke. Prof. Cohen-Armon has found<br />

that the drug is effective in killing cancer cells, while leaving healthy<br />

cells undamaged.<br />

Prof. Cohen-Armon was researching this anti-stroke drug to determine<br />

its effect on signal transmission within the cell nucleus, <strong>and</strong> decided<br />

to examine the compound’s effect on cell division.<br />

Experimentation showed that the compound blocks cell multiplication<br />

in both normal <strong>and</strong> cancer cells. However, healthy cells are able<br />

to recover, while cancer cells die out. “We’ve found a molecular triggering<br />

mechanism in cancer cells that, when set off, causes the cancer<br />

cells to die – they just stop multiplying,” explains Prof. Cohen-Armon.<br />

“Normal, healthy body cells are only temporarily arrested by the same<br />

mechanism. They overcome this cell cycle arrest within 12 hours <strong>and</strong><br />

continue to proliferate.”<br />

Prof. Cohen-Armon says that many human cancer cells the team has<br />

tested in the lab were eradicated by this compound, including breast,<br />

lung, colon, pancreas <strong>and</strong> ovary cancers. This discovery could lead to<br />

an entirely new class of cancer treatment. “If we can specifically target<br />

cancer cells, we will be able to produce a drug that destroys these cells<br />

without worrying about harming the patient’s normal tissue.”<br />

Prof. Cohen-Armon’s team was joined in this research by Asher<br />

Kastiel, a PhD student in Prof. Shai Izraeli’s team at the Department of<br />

Human Molecular Genetics <strong>and</strong> Biochemistry at the Sackler School of<br />

Medicine <strong>and</strong> the Institute for Cancer Research at the Sheba Medical<br />

Center.<br />

Prof. Malka<br />

Cohen-<br />

Armon<br />

Foreign Minister Golda Meir<br />

speaking with participants<br />

from Africa <strong>and</strong> Asia in a<br />

Gadna course, 1961.<br />

21

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