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EEG and Brain Connectivity: A Tutorial - Bio-Medical Instruments, Inc.

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Yoo, S. S. et al. <strong>Inc</strong>reasing cortical activity in auditory areas through<br />

neurofeedback functional magnetic resonance imaging. neuroreport 17,<br />

1273–1278 (2006).<br />

A.1 – Minimization of RMS Error<br />

43- Appendix - A<br />

Time series are sequences, discrete or continuous, of quantitative data of specific<br />

moments in time. They may be simple such as a single numerical observation at each<br />

moment of time <strong>and</strong> studied with respect to their distribution in time, or multiple in which<br />

case they consist of a number of separate quantities tabulated according to a common<br />

time base (e.g., a mixture of sine waves beginning at time = 0).<br />

The statistics of a time series is the science of predicting an immediate or long<br />

time future sequence based on a sample of past sequential quantitative data. In general,<br />

the longer the sample of past quantitative moments of time then the greater the accuracy<br />

of predicting future sequence(s).<br />

The fine details of accuracy of prediction of the future based upon past samples is<br />

generally governed by the relationship of 1 / sq rt. of N. To underst<strong>and</strong> why this is the<br />

case let us define a statistic of a time series based on the “signal” or “message” that is<br />

transmitted <strong>and</strong> the “noise” or r<strong>and</strong>omness that the signal is embedded in. This<br />

relationship was described by the Nobel laureate Normbet Wiener (N. Wiener, Time<br />

Series, MIT Press, Cambridge, Mass., 1949) in which a time series is a combination of a<br />

signal + noise or the signal f(t) <strong>and</strong> the message g(t) + noise, where noise is defined as<br />

f(t) – g(t). In other words noise is defined as the difference between the “message” <strong>and</strong><br />

the measured quantitative values or f(t) – g(t). For example, noise = 0 when f(t) – g(t) =<br />

0.<br />

Let us consider the output of an electrical circuit with input f(t). If the circuit has<br />

the response A (t) to a unit-step function, then the output is given by:<br />

+∞<br />

∫<br />

0<br />

F( t)<br />

= A'<br />

( τ ) f ( t −τ<br />

) dτ<br />

+ A(0)<br />

f ( t)<br />

The goal is to have F(t) approximate as closely as possible the message g(f). That<br />

is, we want to minimize [F(t) – g(t)]. As a criterion<br />

The Ergotic goal of time series statistics is to minimize the difference between the<br />

measured values f(t) <strong>and</strong> the “signal” g(t).

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