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The Safety and Tolerability of Atopaxar (E5555) in ... - summitMD.com

The Safety and Tolerability of Atopaxar (E5555) in ... - summitMD.com

The Safety and Tolerability of Atopaxar (E5555) in ... - summitMD.com

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LANCELOT-ACS<br />

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Inclusion Criteria<br />

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• Male or female; aged 18-80 years<br />

• Present<strong>in</strong>g with features <strong>of</strong> unstable ang<strong>in</strong>a or non-<br />

ST-elevation MI<br />

• At least one <strong>of</strong> the follow<strong>in</strong>g:<br />

1. Tropon<strong>in</strong> T or I or CK-MB upper limit <strong>of</strong> normal<br />

2. ECG changes <strong>com</strong>patible with ischemia (i.e. ST depression<br />

at least 1 mm <strong>in</strong> 2 contiguous leads or T wave <strong>in</strong>version > 3<br />

mm or any dynamic ST shift or transient ST elevation)<br />

• R<strong>and</strong>omization <strong>and</strong> treatment ≤ 72 hours <strong>of</strong> the<br />

onset <strong>of</strong> symptoms

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