The Safety and Tolerability of Atopaxar (E5555) in ... - summitMD.com
The Safety and Tolerability of Atopaxar (E5555) in ... - summitMD.com
The Safety and Tolerability of Atopaxar (E5555) in ... - summitMD.com
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Adapted from Schafer. Am J Med. 1996;101:199-209.<br />
LANCELOT-ACS<br />
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Oral Anti-Platelet <strong>The</strong>rapies<br />
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P2Y 12 Inhibition:<br />
Clopidogrel<br />
Ticlodip<strong>in</strong>e<br />
Prasugrel<br />
Ticagrelor<br />
El<strong>in</strong>ogrel<br />
ADP<br />
ADP<br />
Thromb<strong>in</strong><br />
P2Y 12<br />
ADP<br />
PAR-1 Inhibition:<br />
<strong>Atopaxar</strong> (<strong>E5555</strong>)<br />
Vorapaxar<br />
PAR-1<br />
PLATELET<br />
cAMP<br />
Activation<br />
Collagen<br />
TXA 2<br />
COX<br />
GP IIb/IIIa<br />
(Fibr<strong>in</strong>ogen<br />
receptor)<br />
Aspir<strong>in</strong><br />
TXA 2
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