The Safety and Tolerability of Atopaxar (E5555) in ... - summitMD.com
The Safety and Tolerability of Atopaxar (E5555) in ... - summitMD.com
The Safety and Tolerability of Atopaxar (E5555) in ... - summitMD.com
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Mean TRAP-<strong>in</strong>duced IPA (%)<br />
LANCELOT-ACS<br />
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Platelet Function Data<br />
- Ma<strong>in</strong>tenance Dose Phase -<br />
Thromb<strong>in</strong> receptor-activated peptide (TRAP, 15 µM)-<br />
<strong>in</strong>duced <strong>in</strong>hibition <strong>of</strong> platelet aggregation<br />
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50mg QD<br />
100mg QD<br />
200mg QD<br />
100<br />
80<br />
60<br />
95%<br />
95%<br />
90%<br />
84%<br />
77% 76%<br />
79%<br />
63%<br />
97%<br />
40<br />
20<br />
0<br />
Week 2 Week 4 Week 8<br />
n=42 n=37 n=39
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