ANNUAL REVIEW master Final3a - St Vincent's University Hospital

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Education & Research Poster Presentations in 2007 Fox E, Bielas J, Hyland J, O’Donoghue D, Sheahan K, O’Sullivan J and Loeb L. Mutator phenotype in colon cancer. AACR Special Conference in Cancer Research: Advances in Colon Cancer Research. Nov, 2007; Boston, USA. Cullen G, Tossetto M, Gorman S, Mulcahy HE, O’Donoghue DP, O’Sullivan J. Reduction of interleukin-1ß by cigarette smoke extract – a possible mechanism for disease protection in ulcerative colitis. Poster presentation, ISG Winter Meeting 2007 Milewski M, Moss C, O’Donoghue DP, Sheahan K, Leahy DT. Detection of BRAF mutation in colorectal cancer. 7th Annual UCD Conway Festival of Research, Dublin, September, 2007. E Fox, D Leahy, R Geraghty, H Mulcahy, J Hyland, D Fennelly, D O’Donoghue, K Sheahan Transcriptomic profiling may be useful in predicting recurrence in Stage II colorectal cancer. Irish Association for Cancer Research Annual Meeting, Cork, March, 2007. Coss A, Sheahan K, Sullivan S, Fox E, Hyland J, O'Donoghue D, Leahy D, Mulcahy H, O'Sullivan J Alterations of the topoisomerase II alpha gene and protein in colorectal cancer. Irish Association for Cancer Research Annual Meeting, Cork, March, 2007. A Coss, K Sheahan, S Sullivan, E Fox, J Hyland, D O'Donoghue, D Leahy, H Mulcahy, J O'Sullivan. Amplification of Topoisomerase II· Occurs in Colorectal Cancer and Its Expression Is Associated with Aggressive Disease. (Poster Presentation), Annual Meeting of the American Gastroenterological Association Institute and Digestive Disease Week, Washington, May, 2007. Sheridan J, Wang L, Tosetto M, Dave Kevans, Hyland J, Sheahan K, O’Donoghue D, Mulcahy H & O’Sullivan J. High levels of 8-Hydroxyguanine, a marker of oxidative DNA Damage predicts overall survival in sporadic colorectal cancer. AACR conference on colorectal cancer, Boston, Nov, 2007. S. Gorman, M. Tosetto, H. Mulcahy, O. Howe, F. Lyng, D. O’Donoghue, J. Hyland, D. Fennelly, Gibbons D, Winter D, K. Sheahan & J. O’Sullivan. Gamma ray-induced bystander effects in colorectal cancer: a specific study on cell cycle alterations, cytokine release and early genomic instability events. AACR, Boston, Nov 2007. S. Gorman, M. Tosetto, H. Mulcahy, O. Howe, F. Lyng, D. O’Donoghue, J. Hyland, D. Fennelly, K. Sheahan & J. O’Sullivan. Radiation and chemotherapy bystander effects in ex vivo tumour and matching normal colorectal explants; possible role in secondary tumour formation. IACR, Cork, March 2007. Return to Contents 48
St. Vincent’s Healthcare Group Limited - Annual Review 2007 Education & Research S. Gorman, M. Tosetto, H. Mulcahy, O. Howe, F. Lyng, D. O’Donoghue, J. Hyland, D. Fennelly, Gibbons D, Winter D, K. Sheahan & J. O’Sullivan. Gamma ray-induced bystander effects in colorectal cancer: a specific study on cell cycle alterations, cytokine release and early genomic instability events. ISG, Nov 2007. J Marry, R O’Cearbhaill, J Mackarel, J Crown , D Fennelly. Increased Incidence in Gastrointestinal Perforation associated with Bevacizumab. Irish Association for Cancer Research, Cork, 2 March 2007. Joseph Marry and David Fennelly. Management of Metastatic Colorectal Cancer in a Dublin Teaching Hospital Irish Society of Gastroenterology Spring 2007. J Marry, M Tosetto, H. Mulcahy, J. Hyland, D O’Donoghue, K.Sheahan, D Fennelly, JO’Sullivan. Assessing the effects of monoclonal antibody therapies and telomerase inhibition on pro-angiogenic growth factor secretions in individual human colorectal cancer explants. AACR Special Conference on Advances in Colorectal Cancer, Boston MA, Nov 2007. LM Wang, D Kevans, DP O’Donoghue, HE Mulcahy, J Hyland, J O’Sullivan and K Sheahan. Tumour budding as a prognostic factor in Stage II, pT3N0 colorectal cancer. ISG, April 2007. Kevans D, Foley J, O’Donoghue DP, Hyland JH, Sheahan K, Mulcahy H, O’Sullivan J. High Clusterin expression is associated with poorer prognosis in a cohort of stage II Colorectal Cancer patients. AACR Special Conference “Advances in Colon Cancer Research”Boston November 2007 and Irish Society of Gastroenterology Dublin, November 2007 Kevans D, Wang LM, O’Donoghue DP, Hyland JH, Mulcahy H, Sheahan K, O’Sullivan J. Epithelial- Mesenchymal Transition (EMT) protein expression and mismatch repair profiles in Stage II colorectal cancer with tumour budding status Irish Society of Gastroenterology, Dublin, November 2007. Published Abstracts A Coss, K Sheahan, S Sullivan, E Fox, J Hyland, D O'Donoghue, D Leahy, H Mulcahy, J O'Sullivan (2007) Gastroenterology 132: Suppl. 1, A-293 Amplification of Topoisomerase II· Occurs in Colorectal Cancer and Its Expression Is Associated with Aggressive Disease Cullen G, Keegan D, O’Donoghue DP. Infliximab in Crohn’s Disease: step-up or top-down? Gastroenterology 2007 April; 132:Supplement S1.Poster DDW Washington DC May 2007 Invited Talks Jacintha O’Sullivan. Radiation induced bystander events in colorectal cancer. Irish Society of Radiology Annual Conference, Dublin. October 2007. Jacintha O’Sullivan. Oncologic Therapies for late stage CRC. International CRC meeting. St. Vincents Hospital, Dublin. Sept 2007. Juliette Sheridan. Levels of DNA damage in normal mucosa following radiation. Radiation Conference, Belfast. April 2007. Sheeona Gorman. Examination of Bystander effects using an ex vivo colorectal cancer explant model, ISG, April 2007. Return to Contents 49
Page 3 and 4: Review 2007 St. Vincent’s Healthc
Page 5 and 6: St. Vincent’s Healthcare Group Li
Page 7 and 8: Celebrations • There was a great
Page 9 and 10: Research Studies Total Research Stu
Page 14 and 15: 14 Research
Page 30 and 31: The bioinformatics group moved with
Page 46 and 47: In collaboration with Prof. Kingsto
Page 56 and 57: Education & Research Pharmaceutical
Page 60 and 61: Prestigious Invitations/Honours for
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St. Vincent's Private Hospital Trai
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Report from the Director of Operati
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Report from the Director of Nursing
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Hospital Hygiene Services St. Vince
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Department of Medical Oncology inco
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Department - Medicine at UCD. This
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Department of Cardiology The demand
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Papers Published & Accepted Ponikow
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Department - Medicine Department of
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Department of Endocrinology & Diabe
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Department of Endocrinology & Diabe
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Lios Aoibhinn Cancer Support Centre
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Issues continuing to challenge the
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Department of Nephrology Staff Cons
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Service Developments Neurology in t
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Department of Respiratory Medicine
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Cancer remains a significant focus
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General Services The HACCP system i
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General Services necessitated in ex
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ICT Department Staffing In 2007 we
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Purchasing & Procurement Department
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St. Vincent’s University Hospital
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ANNUAL REVIEW master Final3a - St Vincent's University Hospital

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