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ANNUAL REVIEW master Final3a - St Vincent's University Hospital

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<strong>St</strong>. Vincent’s Healthcare Group Limited - Annual Review 2007<br />

Department of Respiratory Medicine<br />

ECG signal, based on characteristic changes in the ECG that accompany apnoea. In collaboration with Dr.<br />

Lowery, we have developed new surface electrode configurations to record genioglossus EMG with a view<br />

to studying the role of skeletal muscle fatigue in the pathophysiology of OSA.<br />

Honours and Distinctions<br />

Professor McNicholas continues as Chair of a EU COST Action (B26) on obstructive sleep apnoea and as the<br />

founding President of the Irish Sleep Society. Geraldine Nolan continues as Secretary of the Irish Sleep Society.<br />

Visiting Professorship: Prof McNicholas at the <strong>University</strong> of Sydney, August 2007.<br />

Invited Lectures<br />

Prof. McNicholas:<br />

Seventh Annual Ludwig Engel memorial lecture. <strong>University</strong> of Sydney Aug 2007<br />

World Sleep Conference, Cairns Australia Sept 2007<br />

10th International Sleep and Breathing Symposium Palm Cove Australia, Sept 2007.<br />

ERS Research symposium on chronic co-morbidities, Rome Feb 2007<br />

<strong>St</strong>ate of the Art Respiratory Symposium, <strong>University</strong> of Athens, April 2007<br />

Joint COST/ERS Research symposium on interactions of obesity and sleep apnoea, Düsseldorf , Nov 2007<br />

Dr. Silke Ryan: European Respiratory Society, September.<br />

Presentations of original research were given by members of the research team at the annual meeting of the<br />

American Thoracic Society in San Francisco in May (Dr. John Garvey), and the annual meeting of the<br />

European Respiratory Society in <strong>St</strong>ockholm in September (Dr. John Garvey and Dr. Silke Ryan).<br />

Selected Publications 2007 - Prof. McNicholas (see ERC report for complete list).<br />

McNicholas WT, Bonsignore MR; Management Committee of EU COST ACTION B26. Sleep apnoea as<br />

an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research<br />

priorities. Eur Respir J. 2007 Jan;29(1):156-78. Review. PMID: 17197482 [PubMed - indexed for MEDLINE]<br />

Doherty LS, Kiely JL, Deegan PC, Nolan G, McCabe S, Green AJ, Ennis S, McNicholas WT. Late-onset<br />

central hypoventilation syndrome: a family genetic study. Eur Respir J. 2007 Feb;29(2):312-6. PMID:<br />

17264323 [PubMed - indexed for MEDLINE]<br />

McSharry DG, McElwaine P, Segadal L, McNicholas WT. All that wheezes is not asthma. Lancet. 2007 Sep<br />

1;370(9589):800. PMID: 17765530 [PubMed - indexed for MEDLINE]<br />

4. Ryan S, McNicholas WT, Taylor CT. A critical role for p38 map kinase in NF-kappaB signaling during<br />

intermittent hypoxia/reoxygenation. Biochem Biophys Res Commun. 2007 Apr 13;355(3):728-33. Epub<br />

2007 Feb 9. PMID: 17316568 [PubMed - indexed for MEDLINE]<br />

Ryan S, Nolan GM, Hannigan E, Cunningham S, Taylor C, McNicholas WT. Cardiovascular risk markers in<br />

obstructive sleep apnoea syndrome and correlation with obesity. Thorax. 2007 Jun;62(6):509-14. Epub<br />

2007 Jan 24. PMID: 17251313 [PubMed - indexed for MEDLINE]<br />

Return to Contents<br />

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