ANNUAL REVIEW master Final3a - St Vincent's University Hospital

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St. Vincent’s Healthcare Group Limited - Annual Review 2007 Department of Endocrinology & Diabetes Mellitus Research Projects Thyroid Eye Disease Research Group Personnel: Dr Donal O’Shea and Dr Tom Cawood Dr Cawood completed his studies on the potential role of anti-cytokine therapies in thyroid eye disease, and has also investigated the link between smoking and thyroid eye disease. This in vitro work, funded by a Clinical Research Training Fellowship from the Health Research Board, has suggested that Interleukin 1 may be an attractive therapeutic target as Interleukin promotes numerous pathological processes in thyroid eye disease (including inflammation, glycosaminoglycan production and adipogenesis). Interleukin 1 also acts in synergy with cigarette smoke extract to promote adipogenesis, which may help explain why smoking worsens thyroid eye disease. Dr Cawood was awarded the O’Donovan Medal by the Irish Endocrine Society, and the Novartis Endocrinology Registrar Research Medal for this work and was awarded his Ph.D. in 2007. In July 2007 Dr Cawood moved to New Zealand to complete his specialist training. Diabetes & Obesity Research Group Personnel: Dr Donal O’Shea, Dr Jean O’Connell, Dr Lydia Lynch, Dr Mohammed Bashir Dr Conall Dennedy. Laboratory work is underway investigating the metabolic and immunological links between obesity and its consequences, such as type 2 diabetes and non-alcoholic fatty liver disease. A Newman Scholar post is being funded by Sanofi-Aventis, and the Diabetes Federation of Ireland and the Medical Research Charities group have recently awarded funding for a 3-year project entitled ‘Adipocyte size and type 2 diabetes; a study of patients undergoing bariatric surgery’. Dr. O’Connell has been awarded a HRB training fellowship to pursue this project. The group is increasingly focussing also on the link between obesity and cancer. Funding has been secured for another Newman Fellowship to start in early 2008. Dr Bashir is looking at novel urinary biomarkers and diabetes/obesity related kidney disease while Dr Dennedy plans to look at endocanabinoid regulation of adrenal and ovarian steroidogenesis. Clinical Studies (Dr Eoin Noctor, Dr T Smith) For the last ten years that Endocrine Laboratory has screened all blood samples with an elevated prolactin level for the presence of macroprolactin. When macroprolactin was found to account for hyperprolactinaemia, the interpretation was made that when corrected for the presence of macroprolactin, the prolactin level was normal. We have now commenced a study to review the subsequent clinical course of patients whose doctors received this result and interpretation. Questions to be addressed include what additional investigations were undertaken for these patients? What treatments did they receive? What were the final diagnoses? What was the diagnosis? Achievements and Distinctions Professor T J McKenna retired in August 2007 having been associated with St Vincent’s University Hospital since the 1960’s and on the staff as a Consultant since 1978. His retirement was marked by a day given over to reviewing the developments in Diabetes and Endocrinology over that time, with a particular emphasis Return to Contents 190
St. Vincent’s Healthcare Group Limited - Annual Review 2007 Department of Endocrinology & Diabetes Mellitus on his areas of interest. Former colleagues in St Vincent’s including Professor Frank Muldowney and Dr Andrew Heffernan were among the speakers as was Dr Frances Hayes, who has been appointed to take up Professor McKenna’s position in July 2008. Professor McKenna will maintain his academic links with the department. He has been appointed Chairman of the Irish Committee for Higher Medical Education and is a member of the Editorial Boards for the journals Clinical Endocrinology (Oxford) and The Endocrinologist (United States). Dr Donal O’Shea completed his four year term as Secretary of the Irish Endocrine Society. He was a member of the National Taskforce on Obesity and Chairman of the Detection and Treatment Subgroup. Dr O’Shea is Chairman of the Nutrition Council of the Irish Heart Foundation and Chairman of the St Vincent’s Healthcare Group, Drugs and Therapeutics Committee. He received a UCD Premier Award for Undergraduate Teaching Excellence in 2007. Dr Malachi McKenna is a member of the Editorial Board of Osteoporosis International. Dr Ronan Canavan joined the staff as Consultant Endocrinologist in July 2007. Conferences/Courses/Meetings Attended National Cystic Fibrosis Meeting. Killarney, 21st February 2007. Annual Abracadabra Diabetes Nursing Conference. London, 2nd March 2007. International Society for Clinical Densitometry. Tampa, USA, 14th– 7th March 2007. Diabetes Federation of Ireland Multi-disciplinary Diabetes Study Day. Croke Park, 9th March 2007. American Endocrine Society. Toronto, Canada. 2nd-5th June 2007. American Diabetes Association Annual General Meeting and Conference. Chicago, USA, 22nd–26th June 2007. DAFNE Collaborative Meeting, Manchester. 5th-7th July 2007. DAFNE Peer Review and Quality Assurance. Kings College, London. 13th September 2007. Insulin Pump Therapy Training Programme. Mater Misericordiae University Hospital, 27th-28th September 2007. American Society for Bone and Mineral Research. Honolulu, Hawaii, 16th–19th September 2007. Irish Diabetes Nurses Association Annual General Meeting. Dublin, 12th-13th October 2007. Irish Endocrine Society 31st Annual Meeting. Belfast, 2nd-3rd November 2007. DAFNE Ireland Collaborative Meeting. Galway, 1st December 2007. Return to Contents 191
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Review 2007 St. Vincent’s Healthc
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Celebrations • There was a great
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Research Studies Total Research Stu
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14 Research
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In collaboration with Prof. Kingsto
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Education & Research Poster Present
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Education & Research Pharmaceutical
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74 Quality
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St. Michael’s Hospital Nursing Th
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St. Vincent's Private Hospital Cons
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Cancer remains a significant focus
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Department - Urology Consults • 3
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Department - Radiology Radiography
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General Services The HACCP system i
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General Services necessitated in ex
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ICT Department Staffing In 2007 we
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St. Vincent’s University Hospital
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