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Anaesthesia, Intensive Care and Pain Medicine - St Vincent's ...

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Department of Pathology<br />

<strong>St</strong>.Vincent’s Healthcare Group<br />

direction of hospital blood banks.The Department of Health<br />

with the interested parties are presently investigating the<br />

implications of this directive in an attempt to identify the issues<br />

which need to be addressed in order to be compliant with the<br />

directive.<br />

Future Plans<br />

Further development of software for the RAID Computer<br />

dosing program.<br />

Mr. Frank Dennehy was appointed as Surveillance Scientist.<br />

Ms.Ann Flynn <strong>and</strong> Ms.Alison Maguinness were appointed as<br />

Clinical Nurse Specialists in Infection Control.<br />

Service Developments/ Activities<br />

Nuclear <strong>Medicine</strong> Laboratory<br />

New <strong>St</strong>aff<br />

Anne-Marie Glynn BSc joined our staff as a basic-grade<br />

biochemist.<br />

160<br />

It is intended to introduce the next version of the laboratory<br />

computer software in the coming year, this will facilitate the<br />

availability of blood by electronic issue <strong>and</strong> will also improve<br />

traceability by computerising another step in the transfusion<br />

chain.The hospital Transfusion Committee is actively pursuing<br />

barcoding of patient wristb<strong>and</strong>s <strong>and</strong> staff identification badges,<br />

this will further improve safety in blood transfusion.<br />

Haematology Department<br />

<strong>St</strong>aff<br />

Ms Elaine Tallon took up the position of Anticoagulant Nurse<br />

Specialist in Anticoagulant Monitoring Service <strong>and</strong> liases with<br />

patients,GPs <strong>and</strong> hospital doctors. Ms Hazel Black took up a<br />

L a b o ra t o ry Aide position in Haematology.<br />

Service Development/ Activities<br />

The range <strong>and</strong> complexity of tests provided by the<br />

Haematology Laboratory continues to exp<strong>and</strong> in the areas of<br />

immunophenotyping <strong>and</strong> thrombophilia screening. The protocol<br />

for leukaemia typing has been exp<strong>and</strong>ed to include 3-colour<br />

analysis. This allows for more specific typing of tumour cells <strong>and</strong><br />

the detection of minimum residual disease. Since the<br />

introduction of the guidelines for investigation of venous<br />

thromboembolism by the Venous Thromboembolism (VTE)<br />

group, the dem<strong>and</strong> for D-Dimer assay has continued to rise,<br />

with an 18% increase over 2002.<br />

The number of patients attending the Anticoagulant Monitoring<br />

Service continues to increase with approximately 1000 patients<br />

being monitored.The computerised dosing system RAID has<br />

streamlined the service <strong>and</strong> allows for more consisted dosing.<br />

Achievements/ Conferences Attended<br />

Dr. Donald McCarthy became the President of the<br />

Haematology Association of Irel<strong>and</strong>.<br />

Dr. Karen Murphy became the National Specialist Director for<br />

Haematology.<br />

Histopathology Department<br />

<strong>St</strong>aff<br />

June Donnelly joined the secretarial staff.Julie Gorman was<br />

appointed as a Research Scientist with the Colorectal Research<br />

Group, funded through a grant from the <strong>St</strong> Luke’s Institute for<br />

Cancer Research.Shane Sullivan was appointed to a Research<br />

Scientist/Postgraduate Trainee Medical Scientist with the<br />

Colorectal Research Group.<br />

Service Developments<br />

The new mortuary, commissioned in August, is a state of the<br />

art facility, <strong>and</strong> includes an isolation room <strong>and</strong> high-quality<br />

teaching facilities. A ThinPrep instrument was purchased to allow<br />

for the automation <strong>and</strong> optimal preparation of cytology<br />

specimens.<br />

Outst<strong>and</strong>ing/Significant Achievements<br />

John Harford successfully completed the Diploma in Healthcare<br />

Management with the Institute of Public Administration<br />

Future Plans<br />

Introduction of fluorescence ISH for analysis of predictive<br />

markers including HER2 in breast cancer.<br />

Immunology Laboratory<br />

<strong>St</strong>aff<br />

Paul Mc Ardle joined the staff in November.<br />

Conferences<br />

"Automation in Immunology" organised by the Academy of<br />

Medical Laboratory Science, was attended by M.T. Cronin <strong>and</strong><br />

E.Hannigan.<br />

M.T. Cronin attended a "Sebia" User Group Meeting outlining<br />

developments in Immunofixation techniques.<br />

E.Hannigan attended the UK NEQAS User Group Meetings<br />

held in the North General Hospital in Sheffield in October 2003.<br />

The Surveillance Scientist is responsible for the collection <strong>and</strong><br />

analysis of antimicrobial resistance data, (SARI),the reporting of<br />

infectious disease data,(EARSS,CIDR) <strong>and</strong> the production of<br />

regular microbiological data reports as required.<br />

In collaboration with the Pharmacy Department,the<br />

Microbiology Laboratory began a validation of the processes<br />

<strong>and</strong> facilities in the new pharmacy clean room facility, <strong>and</strong><br />

continues to provide an environmental monitoring service on a<br />

daily basis.<br />

Outbreaks of norovirus infection brought its own workload<br />

increase as did the MRSA screening programme which was<br />

tailored to maximise the yield of this organism.<br />

Two large outbreaks of norovirus infection <strong>and</strong> the international<br />

SARS outbreak posed the greatest challenge during the year.<br />

Educational sessions <strong>and</strong> Infection Control audits were<br />

extended to cover all areas,<strong>and</strong> the team joined the <strong>St</strong><br />

Vincent’s Healthcare Group Environment Quality Improvement<br />

Team working towards hospital accreditation.<br />

Future Plans<br />

Microbiology hopes to be inspected for CPA accreditation<br />

within the new facility.The adoption of antibiotic sensitivity<br />

methods to meet NCCLS st<strong>and</strong>ards will begin immediately as<br />

well as development of microbiological PCR techniques within<br />

the Molecular Biology Laborator y. Environmental monitoring is a<br />

developing area <strong>and</strong> we hope to provide a more<br />

comprehensive service to the users of our service.<br />

Microbiology – Professorial Unit<br />

Achievements<br />

Prof.William Hall;Adjunct Professor,The Rockefeller University,<br />

New York,USA.Elected to the Board of the Institute of Human<br />

Virology, Baltimore, USA, <strong>and</strong> elected to the Membership<br />

committee, Kunkel Society, Rockefeller University, New York,<br />

USA.<br />

Outst<strong>and</strong>ing/Significant Achievements<br />

Dr. Joe Duffy was made an Adjunct Professor in the Medical<br />

Faculty at University College Dublin.Prof.Duffy was also invited<br />

to Chair the National Academy of Clinical Biochemistry (USA)<br />

Panel to establish new guidelines for the Clinical Use of Markers<br />

in Breast Cancer.<br />

Prof.Joe Duffy was invited to speak at a number of<br />

international meetings in 2003, including:<br />

Association of Clinical Biochemist (UK) Focus Meeting<br />

Manchester:Title of Lecture, Evidence for the use of tumor<br />

markers.<br />

XXXI International Society for Oncodevelomental Biology <strong>and</strong><br />

<strong>Medicine</strong> (ISOBM) Edinburgh:Title of Lecture, uPA <strong>and</strong> PAI-1:<br />

validated prognostic markers in breast cancer.<br />

Continuing Education Meeting in Clinical Biochemistry<br />

Windermere (UK):Title of lecture, Prostate cancer: to screen or<br />

not screen ?.<br />

Association of Clinical Biochemists Irel<strong>and</strong>,Annual Conference<br />

Dublin:Title of lecture:Tumor markers,current <strong>and</strong> future uses.<br />

Publications<br />

O’Donovan N, Crown J,<strong>St</strong>unell H, Hill A,McDermott E,<br />

O’Higgins N, Duffy MJ. Caspase 3 in breast cancer. Clin Cancer<br />

Res 2003;9:783-742.<br />

Duffy MJ,van Dalen A,Haglund L,Klapdor R, Lamerz R,<br />

Nilsson O, <strong>St</strong>urgeon C,Topolcan O. Clinical Utility of<br />

biochemical markers in colorectal cancer : European<br />

Group on Tumour Markers (EGTM) Guidelines. Eur J<br />

Cancer 2003;39:718.<br />

161<br />

Mr. Ivan Shirley became a member of the <strong>St</strong>eering Committee<br />

of the Irish External Quality Assessment Scheme.<br />

The following attended at <strong>and</strong> contributed to posters presented<br />

at the Haematology Association of Irel<strong>and</strong>: B. Collins, C. Fleming,<br />

I.Shirley, C. Waldron <strong>and</strong> P. Crosby.<br />

Microbiology Laboratory<br />

<strong>St</strong>aff<br />

Ms.Anne Brady <strong>and</strong> Ms. Elaine Garvey were promoted to<br />

Senior Medical Scientists.Ms.Deirdre Keating <strong>and</strong> Ms.Elizabeth<br />

Doyle took up permanent medical scientist posts in September.<br />

Prof.William Hall is on the editorial boards of:AIDS Research<br />

<strong>and</strong> Human Retroviruses,Neuropathology, Journal of<br />

Neurovirology <strong>and</strong> Journal of the Acquired Immunodeficiency<br />

Syndrome (JAIDS).

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