Anaesthesia, Intensive Care and Pain Medicine - St Vincent's ...
Anaesthesia, Intensive Care and Pain Medicine - St Vincent's ...
Anaesthesia, Intensive Care and Pain Medicine - St Vincent's ...
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Department of Metabolism<br />
<strong>St</strong>.Vincent’s Healthcare Group<br />
Department of<br />
Medical Oncology<br />
Departmental Review<br />
108<br />
compliance with Clinical Pathology Accreditation (CPA )<br />
requirements.<br />
Representative Functions<br />
Barbara Murray is a member of the Executive Committee of<br />
Eurachem Irel<strong>and</strong>.<br />
Meetings attended by Department Personnel<br />
Roche 2nd Irel<strong>and</strong> User Group Forum<br />
Dublin,27th – 29th May 2003<br />
Nutrition Society Meeting ( Optimal Nutrition for Osteoporosis<br />
Prevention )<br />
Cork,18th – 20th June 2003<br />
Irish Endocrine Society<br />
Armagh, 7th – 8th November 2003<br />
Annual Conference of the Association of Clinical Biochemists<br />
Malahide, 14th – 15th November 2003<br />
Publications<br />
Suliman AM, Freaney R,Smith TP, McBrinn Y, Murray B, McKenna<br />
TJ. The Impact of Different Glucocorticoid Replacement schedules<br />
on Bone Turnover <strong>and</strong> Insulin Sensitivity in Patients with Adrenal<br />
Insufficiency.<br />
Clin Endocrinol (Oxf) 2003 59(3): 380-87<br />
Murphy E,Freaney R,Bresnihan B, McKenna M, Fitzgerald O.<br />
Increased Bone Resorption <strong>and</strong> Failure to Respond to Antiresorptive<br />
Therapy in Progressive Dystrophic Calcification.<br />
Calcif Tissue Int.2003 Nov;73(5) :433-40<br />
Abstract<br />
Smith D, Murray B, Gibney J, McKenna TJ.<br />
Application of new Indices of Bone activity for evaluation of the<br />
response to treatment of Hyperthyroidism <strong>and</strong> Paget’s Disease.<br />
Ir. J.Med. Sci.2003;172(4):17<br />
2003 was a highly successful period of growth for the Medical<br />
Oncology Department of <strong>St</strong>.Vincent’s Healthcare Group. As<br />
before, patient activities were concentrated in the <strong>St</strong>.Anne’s<br />
Ward complex.As is the case throughout the medical oncology<br />
world,increasing the focus of acute cancer therapeutics in the<br />
ambulatory setting,<strong>and</strong> the oncology day ward / outpatients<br />
area,continued to provide a high quality service, to increasing<br />
numbers of cancer patients.<br />
Research protocols resumed in the division in the Summer of<br />
2003. The flagship clinical trials from the breast programme<br />
remained the BCIRG 006 <strong>and</strong> 007 studies,both of which<br />
neared the completion of their accrual during 2003.Both these<br />
studies are chaired/co-chaired by <strong>St</strong>.Vincent’s investigators.<br />
On the educational front,post-clinic teaching conferences are<br />
held approximately twice per week.<br />
Professor Crown was awarded the Thomas Baldwin Chair in<br />
Translational Cancer Research by Dublin City University, in<br />
recognition of an ongoing research affiliation between <strong>St</strong>.<br />
Vincent’s <strong>and</strong> that institution, which complements our existing<br />
relationships with University College Dublin.Research projects<br />
in drug resistance conducted by Dr. Michael O’Leary reached<br />
their completion during 2003. Ms Brigid Browne commenced<br />
work as a doctoral student in the area of HER-2 biology, jointly<br />
in DCU <strong>and</strong> UCLA.Professor Crown was elected to the<br />
Educational Committee of the American Society of Clinical<br />
Oncology.<br />
Meetings<br />
In 2003,Professor Crown lectured or presented at the Post San<br />
Antonio meeting for German Gynaecologists,Munich;the Miami<br />
Breast Cancer Conference;Anglo Celtic meetings,London,<br />
Sheffield & Leuven;Various Aventis Advisory Board Meetings;<br />
Herceptin meeting,Dublin;ESGO Congress,Brussels; Oncology<br />
Speakers Bureau,L.A.,New York <strong>and</strong> Chicago;ASCO, Chicago;<br />
ASCO Education Committee Meeting,Chicago;ECCO,<br />
Copenhagen;Austrian Society of Surgical Oncology meeting,<br />
Vienna;Third International Symposium on Translational<br />
Research,California;Breast Cancer Symposium,New Jersey;<br />
ICORG <strong>St</strong>rategy Meeting;Annual San Antonio Breast Cancer<br />
Symposium,December.<br />
Abstracts 2003<br />
Crown J, Leyvraz S,Verrill M,Guillem V, Efremedis A, Garcia<br />
Conde-Bru J, Welsh R, Montes A,Leonard R,Baselga J.<br />
Superiority of T<strong>and</strong>em High-Dose (HDC) Over Conventionally-<br />
Dosed Chemotherapy (CDC) in Patients (Pts) with Metastatic<br />
Breast Cancer (MBC):Updated Results of the International<br />
R<strong>and</strong>omised Breast Cancer Dose-Intensity <strong>St</strong>udy (IBDIS).Ann<br />
Meet Am Soc Clin Onco 22:88,2003.<br />
Crown J, Leyvraz S,Verrill M,Guillem V, Efremedis A, Garcia-<br />
Conde-Bru J, Welsh R, Montes A,Leonard R,Baselga J.<br />
Superiority of T<strong>and</strong>em High-Dose Over conventionally-dosed<br />
Chemotherapy in Patients with Metastatic Breast Cancer:<br />
Updated Results of the International R<strong>and</strong>omised Breast Cancer<br />
Dose-Intensity <strong>St</strong>udy (IBDIS).Eur J Can Supp 1: 5,S134,2003.<br />
Donnellan P, Crown J, Hall W. HTLV seroprevalence in Irish<br />
populations is low.Ann Meet Am Soc Clin Onco 22: 3 5 5 1 ,2 0 0 3 .<br />
Publications 2003<br />
O’Donovan N, Crown J,<strong>St</strong>unell H, Hill AD, McDermott E,<br />
O’Higgins N,Duffy MJ. Caspase 3 in breast cancer. Clin Cancer<br />
Res.2003 Feb;9(2):738-42.<br />
Ballot J,McDonnell D, Crown J. Successful treatment of<br />
thrombocytopenia due to marrow metastases of breast cancer with<br />
weekly docetaxel. J Natl Cancer Inst.2003 Jun 4;95(11):831-2.<br />
Crown J, Pegram M. Platinum-taxane combinations in metastatic<br />
breast cancer: an evolving era of molecularly targeted therapy.<br />
Breast Cancer Res Treat.2003; 79 Suppl 1:S11-8.Review.<br />
Crown J. Chemotherapy dose <strong>and</strong> schedule in adjuvant treatment<br />
of breast cancer: phoenix,turkey or dodo? Lancet 2003 Aug 30;<br />
362(9385):677-8.<br />
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