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PRODUCT CATALOGUE - Stop TB Partnership

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GLOBAL DRUG FACILITY<br />

<strong>PRODUCT</strong> <strong>CATALOGUE</strong><br />

First, second and third line<br />

anti-<strong>TB</strong> medicines<br />

The Global Drug Facility (GDF)<br />

aims to ensure the timely<br />

delivery of first- and secondline<br />

tuberculosis drugs and<br />

diagnostics at sustainable prices.<br />

www.stoptb.org/gdf


The benefits of GDF quality-assured products<br />

GDF products enable physicians to treat patients according to the latest WHO treatment guidelines. All GDF products are on the<br />

WHO Essential Medicines List, which facilitates registration and importation. The use of Fixed Dose Combination (FDC) tablets<br />

greatly contributes to rational drug use and assists in effective implementation and expansion of the STOP <strong>TB</strong> Strategy. FDC tablets<br />

reduce the number of tablets a patient needs to take, while avoiding mono-therapy and thereby reduce the risks of developing<br />

Multidrug-Resistant <strong>TB</strong> (MDR-<strong>TB</strong>).<br />

GDF has adopted standards for blister design which specify the layout, materials, markings and colour coding that should be used.<br />

These blister packs offer the same shelf life as loose drugs at similar or lower costs, help health workers identify the drugs needed,<br />

provide better protection for the tablets once the container is opened and can be used in all situations and health facilities.<br />

FIRST LINE ANTI-TUBERCULOSIS MEDICINES<br />

Oral solid dosage forms: Fixed Dose Combinations for adults<br />

<strong>PRODUCT</strong> DESCRIPTION PRICE EXW (USD)<br />

4FDC/RHZE 150/75/400/275<br />

(blister)<br />

4FDC/RHZE 150/75/400/275<br />

(loose)<br />

3FDC/RHE 150/75/275<br />

(blister)<br />

3FDC/RHE 150/75/275<br />

(loose)<br />

2FDC/RH 150/75<br />

(blister)<br />

2FDC/RH 150/75<br />

(loose)<br />

2FDC/EH 400/150<br />

(blister)<br />

Rifampicin 150 mg / Isionazid 75 mg / Pyrazinamide 400 mg / Ethambutol 275 mg film-coated<br />

tablets. PvC/Alu film blister pack of 28 tablets x 24 blisters<br />

Rifampicin 150 mg / Isionazid 75 mg / Pyrazinamide 400 mg / Ethambutol 275 mg film-coated<br />

tablets. 1000 loose tablets in HDPE container<br />

Rifampicin 150 mg / Isionazid 75 mg / Ethambutol 275 mg film-coated tablets. PvC/Alu film<br />

blister pack of 28 tablets x 24 blisters<br />

Rifampicin 150 mg / Isionazid 75 mg / Ethambutol 275 mg film-coated tablets. 1000 loose tablets<br />

in HDPE container<br />

Rifampicin 150 mg / Isionazid 75 mg film-coated tablets. PvC/Alu film blister pack of<br />

28 tablets x 24 blisters<br />

Rifampicin 150 mg / Isionazid 75 mg film-coated tablets. 1000 loose tablets in HDPE container<br />

Ethambutol 400 mg / Isionazid 150 mg film-coated tablets. PvC/Alu film blister pack of 28 tablets<br />

x 24 blisters<br />

43.70<br />

57.29<br />

53.57<br />

77.90<br />

20.10<br />

24.92<br />

20.80<br />

Oral solid dosage forms: Single dose formulations for adults<br />

<strong>PRODUCT</strong> DESCRIPTION PRICE EXW (USD)<br />

Ethambutol 400 mg<br />

(blister)<br />

Isoniazid 300 mg<br />

(blister)<br />

Pyrazinamide 400 mg<br />

(blister)<br />

Ethambutol 400mg film-coated tablets. PvC/Alu film blister pack of 28 tablets x 24 blisters<br />

Isoniazid 300mg film-uncoated tablets. PvC/Alu film blister pack of 28 tablets x 24 blisters<br />

Pyrazinamide 400mg film- uncoated tablets. Alu/PvC film blister pack of 28 tablets x 24 blisters<br />

* This price is for indicative purposes. Lower prices may be available following a request for quotations (RFQ) for consolidated orders.<br />

Oral solid dosage forms: Fixed dose combinations for children<br />

<strong>PRODUCT</strong> DESCRIPTION PRICE EXW (USD)<br />

3FDC/RHZ 60/30/150<br />

(blister)<br />

2FDC/RH 60/60<br />

(blister)<br />

2FDC/RH 60/30<br />

(blister)<br />

Rifampicin 60 mg/ Isionazid 30 mg/ Pyrazinamide 150 mg dispersible tablets.<br />

PvC/Alu film blister pack of 28 tablets x 3 blisters<br />

Rifampicin 60 mg / Isionazid 60 mg dispersible tablets. PvC/Alu film blister pack of<br />

28 tablets x 3 blisters<br />

Rifampicin 60 mg/Isionazid 30 mg dispersible tablets. PvC/Alu film blister pack of<br />

28 tablets x 3 blisters<br />

18.30<br />

13.52*<br />

10.75<br />

6.00<br />

3.00<br />

4.00<br />

Oral solid dosage forms: Single dose formulations for children<br />

<strong>PRODUCT</strong> DESCRIPTION PRICE EXW (USD)<br />

Isoniazid 100 mg<br />

(blister)<br />

Ethambutol 100 mg<br />

(blister)<br />

Isoniazid 100 mg dispersible tablets. PvC/Alu film blister pack of 10 tablets<br />

x 10 blisters<br />

Ethambutol 100 mg dispersible tablets. PvC/Alu film blister pack of 10 tablets<br />

x 10 blisters<br />

2.02<br />

3.26<br />

Parenteral injectables<br />

<strong>PRODUCT</strong> DESCRIPTION PRICE EXW (USD)<br />

Streptomycin 1 g inj<br />

(vial)<br />

Streptomycin 1 g powder for injection. 100 vials in a box<br />

68.00


Pre-shipment inspection is conducted on all orders by an international agency, independent of the manufacturer, to verify the<br />

shipment documentation, quantity and integrity of products, labelling and expiry dates. Randomized sampling and testing is<br />

conducted by an accredited laboratory to ensure that batches comply with established quality specifications.<br />

GDF is able to achieve very competitive prices for quality assured products through competitive bidding and bulk procurement.<br />

Prices listed indicate the base cost of the product and do not include costs for procurement agent fees, quality control, pre-shipment<br />

inspection, transport (air freight or sea freight) or insurance. Prices are provided for indicative purposes only and are based on the<br />

highest price offered for a product by a contracted supplier. It is noted that for many products, GDF has multiple suppliers and<br />

cheaper prices may be available upon a request for quotation, in addition to consolidation of orders and bulk quantity discounts.<br />

SECOND LINE ANTI-TUBERCULOSIS MEDICINES<br />

Oral solid dosage forms: Fluoroquinolones<br />

<strong>PRODUCT</strong> DESCRIPTION PRICE EXW (USD)<br />

Ofloxacin 200 mg<br />

(blister)<br />

Ofloxacin 400 mg<br />

(blister)<br />

Levofloxacin 250 mg<br />

(blister)<br />

Levofloxacin 500 mg<br />

(blister)<br />

Moxifloxacin 400 mg<br />

(blister)<br />

Ofloxacin 200 mg film-coated tablets. PvC/Alu film blister pack of 10 tablets / 10 blisters<br />

in a carton box<br />

Ofloxacin 400 mg film-coated tablets. PvC/Alu film blister pack of 10 tablets / 10 blisters<br />

in a carton box<br />

Levofloxacin 250mg film-coated tablets. PvC/Alu film blister pack of 100 tablets<br />

Levofloxacin 500mg film-coated tablets. PvC/Alu film blister pack of 100 tablets<br />

Moxifloxacin 400mg film-coated tablets. PvC/Alu or Alu/Alu film blister pack of 5 tablets<br />

5.00<br />

9.00<br />

5.50<br />

7.85<br />

8.40<br />

Oral solid dosage forms: Bacteriostatics Second Line Drugs<br />

<strong>PRODUCT</strong> DESCRIPTION PRICE EXW (USD)*<br />

Ethionamide 250 mg<br />

(blister)<br />

Prothonamide 250 mg<br />

(blister)<br />

Prothonamide 250 mg<br />

(loose)<br />

Cycloserine 250 mg<br />

(strips)<br />

Cycloserine 250 mg<br />

(loose-100 caps)<br />

PAS Acid<br />

(sachets)<br />

PAS Sodium<br />

(powder for oral solution- sachets)<br />

PAS Sodium<br />

(enteric coated granules- container)<br />

PAS Sodium<br />

(enteric coated granules- sachets)<br />

Terizidone 250 mg<br />

(blister)<br />

Ethionamide 250mg film-coated tablets. PvC/Alu and Alu/Alu strips of 10 tablets x 10 blisters<br />

in a carton box<br />

Prothonamide 250mg film-coated tablets. PvC/Alu film blister of 10 tablets x 10 blisters<br />

in a carton box<br />

Prothonamide 250 mg film-coated tablets. 50 tablets on LPDE bag placed in HDPE container<br />

Cycloserine 250mg hard capsules. Alu/Alu strip pack of 10 capsules x 10 blisters in a carton box<br />

Cycloserine 250mg hard capsules. 100 capsules on LPDE bag placed in HDPE container<br />

P-aminosalycilic acid (PAS) 4 g enteric coated delayed-release granules in sachets.<br />

30 Alu/PET/Alu/LLDPE sachets in a carton box<br />

P-aminosalicylate sodium salt powder for oral solution 5.52 g sachet. 25 Alu/PET/Alu/LLDPE<br />

laminated sachets / 1 carton box<br />

P-aminosalicylate sodium enteric coated delayed-release granules 60% w/w, 100 g HDPE container.<br />

100gr in LPDE bag placed in HDPE container<br />

P-aminosalicylate sodium enteric coated delayed-release granules 60% w/w, 9.2 g sachets.<br />

30 PET/Alu/LLDPE sachets of 9.2 g/ 1 carton box<br />

Terizidone 250 mg capsules. Alu/PvC blister pack of 10 hard capsules x 5 blisters in a carton box<br />

8.25<br />

€ 10.15<br />

4.07<br />

59.09<br />

78.14**<br />

46.00<br />

37.50<br />

16.00<br />

43.50<br />

€ 59.00<br />

* Unless otherwise stated<br />

** Procurement of this product is on a case by case basis if countries specifically request this packaging size<br />

Parenteral Injectables<br />

<strong>PRODUCT</strong> DESCRIPTION PRICE EXW (USD)<br />

Capreomycin 1 g inj<br />

(Powder for injection)<br />

Kanamycin 1 gr inj<br />

(Solution for injection)<br />

Amikacin 500 mg inj<br />

(Solution for Injection)<br />

Capreomycin 1 g powder for injection. 1 vial/ampoule in a carton box<br />

Kanamycin 1 g solution for injection (4 ml). 10 vials/ampoules in a carton box<br />

Amikacin 500mg solution for injection (2 ml). 10 vials/ampoules in a carton box<br />

8.00<br />

25.8<br />

€ 7.63


THIRD LINE ANTI-TUBERCULOSIS MEDICINES<br />

<strong>PRODUCT</strong> DESCRIPTION PRICE EXW (USD)<br />

Amoxicilin clavunate 875 + 125 mg<br />

Amoxicilin clavunate 875+ 125 mg film coated tablets. PvC/ALU film blister pack of<br />

14 tablets in a carton box<br />

€ 3.48<br />

STOP <strong>TB</strong> PATIENT KITS<br />

<strong>PRODUCT</strong> DESCRIPTION PRICE EXW (USD)<br />

Cat I & III Kit A<br />

<strong>Stop</strong> <strong>TB</strong> Cat. I+III Patient Kit A: 6 blisters (168) 4-FDC tablets<br />

(R150/H75/Z400/E275); 12 blisters (336) 2-FDC tablets (R150/H75)<br />

22.30<br />

Cat I & III Kit B<br />

<strong>Stop</strong> <strong>TB</strong> Cat. I+III Patient Kit B: 6 blisters (168) 4-FDCs<br />

(R150/H75/Z400/E275); 18 blisters (504) 2-FDC tablets (E400/H150)<br />

32.27<br />

MEDICAL DEVICES AND WATER FOR INJECTION<br />

<strong>PRODUCT</strong> DESCRIPTION PRICE EXW (USD)<br />

Water for injection 5 ml ampoule<br />

Hypodermic AD syringes with reuse<br />

prevention feature, 5 ml (21G)<br />

Hypodermic AD syringes with reuse<br />

prevention feature, 5 ml (23G)<br />

Safety box for used syringes<br />

and needles 5lt<br />

Water for injection, sterile, 5 ml plastic ampoules. 100 ampoules in a box<br />

Hypodermic syringes with automatic disabling (AD) feature, capacity of 5ml, sterile,<br />

for reconstitution and injection. 100 pieces in a box<br />

Hypodermic syringes with automatic disabling (AD) feature, capacity of 5ml, sterile,<br />

for reconstitution and injection. 100 pieces in a box<br />

Safety box for used syringes/needles, 5 lt box of 25<br />

10.60<br />

5.75<br />

5.75<br />

17.25<br />

Global Drug Facility<br />

<strong>Stop</strong> <strong>TB</strong> <strong>Partnership</strong><br />

c/o World Health Organization<br />

20 Avenue Appia<br />

1211 Geneva 27<br />

Switzerland<br />

www.stoptb.org/gdf

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