2010 Corporate Capabilities - Spectroscopy
2010 Corporate Capabilities - Spectroscopy
2010 Corporate Capabilities - Spectroscopy
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Volume 24 Number 12 SPECTROSCOPY CORPORATE CAPABILITIES ISSUE December 2009<br />
December 2009 Volume 24 Number 12<br />
www.spectroscopyonline.com<br />
<strong>2010</strong> <strong>Corporate</strong><br />
<strong>Capabilities</strong><br />
Get More Value from<br />
Your Spectrometer<br />
Group Theory and<br />
Symmetry, Part I<br />
®
te<br />
4 <strong>Spectroscopy</strong> 24(12) December 2009 www.spectroscopyonline.com<br />
®<br />
®<br />
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Joseph Loggia<br />
President, Chief Executive Officer<br />
Ted Alpert<br />
Executive Vice President, Finance & Chief Financial Officer<br />
Eric I. Lisman<br />
Executive Vice President, <strong>Corporate</strong> Development<br />
Tony Calanca<br />
Executive Vice President, Exhibitions<br />
Chris DeMoulin<br />
Executive Vice President, Fashion Group<br />
Danny Phillips<br />
Executive Vice President, Powersports, Veterinary & Dental Group<br />
Georgiann DeCenzo<br />
Executive Vice President, Market Development, Europe & Licensing Group<br />
Steve Morris<br />
Executive Vice President, Life Sciences Group<br />
Francis Heid<br />
Vice President, Media Operations<br />
J Vaughn<br />
Vice President, Information Technology<br />
Mike Alic<br />
Vice President, Electronic Media Group<br />
Nancy Nugent<br />
Vice President, Human Resources<br />
Ward D. Hewins<br />
Vice President, General Counsel<br />
David C. Esola<br />
Vice-President, General Manager<br />
s10-20% Post Consumer Wa<br />
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6 <strong>Spectroscopy</strong> 24(12) December 2009 www.spectroscopyonline.com<br />
Contents<br />
Volume 24 Number 12<br />
DECember 2009<br />
December 2009<br />
Volume 24 Number 12<br />
December 2009 Volume 24 Number 12<br />
www.spectroscopyonline.com<br />
<strong>2010</strong> <strong>Corporate</strong><br />
<strong>Capabilities</strong><br />
Get More Value from<br />
Your Spectrometer<br />
Group Theory and<br />
Symmetry, Part I<br />
Cover image courtesy of<br />
Robin MacDougall/Getty Images.<br />
®<br />
Columns<br />
THE BASELINE<br />
Group Theory and Symmetry, Part I: Symmetry Elements<br />
Group theory is the field of mathematics that includes, among other things, the treatment<br />
of symmetry. Well, it turns out that molecules have symmetry, so group theoretical<br />
principles can be applied to molecules. Because spectroscopy uses light to probe the<br />
properties of molecules, it might not be surprising that group theory has some application<br />
to spectroscopy. Here, we start a multipart discussion of symmetry and group theory.<br />
David W. Ball<br />
Are You Getting Value From Your Spectrometer?<br />
Getting the best business value from a spectrometer requires knowledge of the instrument<br />
and its operating abilities, any attachments, the sample including sampling procedure and<br />
presentation, and the software. All of these elements must be pulled together by a skilled<br />
and knowledgeable spectroscopist. Unfortunately, this is not always the case in many<br />
organizations.<br />
R.D. McDowall<br />
FOCUS ON QUALITY<br />
63<br />
67<br />
DEPARTMENTS<br />
From the Editor 10<br />
News Spectrum 11<br />
Articles<br />
2009 Editorial Index 73<br />
<strong>Spectroscopy</strong> presents its annual index of authors and articles as a resource for readers and<br />
researchers.<br />
www.spectroscopyonline.com<br />
● Article Archive<br />
● Calendar of Events<br />
● Information for Authors<br />
● Useful Links<br />
● Application Notes<br />
● Subscribe/Renew Information<br />
... and more!<br />
<strong>Spectroscopy</strong> (ISSN 0887-6703 [print], ISSN 1939-1900 [digital]) is published monthly by Advanstar Communications, Inc.,<br />
131 West First Street, Duluth, MN 55802-2065. <strong>Spectroscopy</strong> is distributed free of charge to users and specifiers of spectroscopic<br />
equipment in the United States. <strong>Spectroscopy</strong> is available on a paid subscription basis to nonqualified readers<br />
at the rate of: U.S. and possessions: 1 year (12 issues), $74.95; 2 years (24 issues), $134.50. Canada/Mexico: 1 year, $95; 2 years,<br />
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This Month in Wavelength:<br />
FT-IR/NIR<br />
Watch your e-mail inbox for the latest<br />
issue, or follow the link at<br />
www.spectroscopyonline.com to sign up to<br />
start receiving Wavelength.
8 <strong>Spectroscopy</strong> 24(12) December 2009<br />
www.spectroscopyonline.com<br />
December 2009 Volume 24 Number 12<br />
<strong>2010</strong> <strong>Corporate</strong> <strong>Capabilities</strong><br />
12 ABB Analytical<br />
14 Amptek, Inc.<br />
16 Applied Photophysics<br />
18 Andor Technology plc<br />
19 Avantes, Inc.<br />
20 B&W Tek, Inc.<br />
22 BaySpec, Inc.<br />
23 Bruker Corporation<br />
24 EDAX, Inc.<br />
26 CVI Melles Griot<br />
27 Fiberguide Industries, Inc.<br />
28 FOSS NIRSystems, Inc.<br />
29 Glass Expansion<br />
30 Harrick Scientific Products, Inc.<br />
31 Hitachi High Technologies America<br />
32 HORIBA Scientific<br />
33 OptiGrate Corp.<br />
34 International Centre for Diffraction<br />
Data (ICDD)<br />
36 IDEX Health & Science<br />
38 Inorganic Ventures<br />
40 KLASTECH Karpushko Laser<br />
Technologies<br />
42 Moxtek, Inc.<br />
44 Newport Corporation<br />
45 Nippon Instruments North<br />
America<br />
46 Ocean Optics, Inc.<br />
48 PANalytical<br />
50 Parker Hannifin Corporation<br />
51 PerkinElmer<br />
52 PHOTONIS USA<br />
54 PIKE Technologies<br />
55 Smiths Detection Scientific<br />
83 <strong>Spectroscopy</strong><br />
56 Shimadzu Scientific Instruments<br />
58 Specac, Inc.<br />
59 Spellman High-Voltage<br />
Electronics<br />
60 SPEX CertiPrep, Inc.<br />
61 Thermo Fisher Scientific<br />
62 WITec GmbH
www.spectroscopyonline.com December 2009 <strong>Spectroscopy</strong> 24(12) 9<br />
Editorial Advisory Board<br />
Ramon M. Barnes University of Massachusetts<br />
Paul N. Bourassa Lifeblood<br />
Chris W. Brown University of Rhode Island<br />
Kenneth L. Busch Wyvern Associates<br />
Ashok L. Cholli University of Massachusetts at Lowell<br />
David M. Coleman Wayne State University<br />
Patricia B. Coleman Ford Motor Company<br />
Bruce Hudson Syracuse University<br />
Kathryn S. Kalasinsky Armed Forces Institute of Pathology<br />
David Lankin University of Illinois at Chicago, College of Pharmacy<br />
Barbara S. Larsen DuPont Central Research and Development<br />
Ian R. Lewis Kaiser Optical Systems<br />
Jeffrey Hirsch ThermoFisher Scientific<br />
Howard Mark Mark Electronics<br />
R.D. McDowall McDowall Consulting<br />
Linda Baine McGown Rensselaer Polytechnic Institute<br />
Robert G. Messerschmidt Rare Light, Inc.<br />
Nancy Miller-Ihli M–I Research<br />
Francis M. Mirabella Jr. Equistar Technology Center<br />
John Monti Shimadzu Scientific Instruments<br />
Thomas M. Niemczyk University of New Mexico<br />
Anthony J. Nip CambridgeSoft Corp.<br />
John W. Olesik The Ohio State University<br />
Richard J. Saykally University of California, Berkeley<br />
Basil I. Swanson Los Alamos National Laboratory<br />
Jerome Workman Jr. Luminous Medical, Inc.<br />
Contributing Editors:<br />
Fran Adar Horiba Jobin Yvon<br />
David W. Ball Cleveland State University<br />
Kenneth L. Busch National Science Foundation<br />
John Coates Coates Consulting<br />
Howard Mark Mark Electronics<br />
Volker Thomsen Consultant<br />
Jerome Workman Jr. Luminous Medical, Inc.<br />
Process Analysis Advisory Panel:<br />
James M. Brown Exxon Research and Engineering Company<br />
Bruce Buchanan Sensors-2-Information<br />
Lloyd W. Burgess CPAC, University of Washington<br />
James Rydzak Glaxo SmithKline<br />
Robert E. Sherman CIRCOR Instrumentation Technologies<br />
John Steichen DuPont Central Research and Development<br />
D. Warren Vidrine Vidrine Consulting<br />
European Regional Editors:<br />
John M. Chalmers VSConsulting, United Kingdom<br />
David A.C. Compton Industrial Chemicals Ltd.<br />
<strong>Spectroscopy</strong>’s Editorial Advisory Board is a group of distinguished individuals<br />
assembled to help the publication fulfill its editorial mission to promote the effective<br />
use of spectroscopic technology as a practical research and measurement tool.<br />
With recognized expertise in a wide range of technique and application areas, board<br />
members perform a range of functions, such as reviewing manuscripts, suggesting<br />
authors and topics for coverage, and providing the editor with general direction and<br />
feedback. We are indebted to these scientists for their contributions to the publication<br />
and to the spectroscopy community as a whole.
10 <strong>Spectroscopy</strong> 24(12) December 2009 www.spectroscopyonline.com<br />
From the Editor<br />
Looking Forward with Optimism<br />
It has certainly been a long 12 months. With the economic recession, the housing crisis,<br />
and high unemployment dominating the news and impacting the spectroscopy marketplace<br />
in 2009, it is easy to see why many readers will not be sorry to see the end of 2009,<br />
and why they will be all too happy to welcome in <strong>2010</strong>.<br />
However, if the holidays are a time for looking forward with optimism, then it must also be<br />
said that even in these difficult economic times, there is ample reason to feel hopeful. A recent<br />
market analysis from Strategic Directions International points to high single-digit growth in<br />
all market segments in <strong>2010</strong>, with atomic spectroscopy, molecular spectroscopy, and mass spectrometry<br />
all predicted to grow in the coming year (see pp. 10–16 of <strong>Spectroscopy</strong>’s “Buyers’ Guide<br />
and Industry Trends,” August 2009). And with a modest yet steady rally brewing on Wall Street<br />
over the past few months and an improving housing market, there are indeed reasons to look<br />
forward to <strong>2010</strong>.<br />
Here at <strong>Spectroscopy</strong>, one thing we are looking forward to is bringing readers another year of<br />
practical technical advice and information to help them in their labs every day. For make no<br />
mistake, it is the everyday work being done on the frontlines of materials analysis and analytical<br />
chemistry in general that will help bring about the economic recovery we are all putting on our<br />
wish lists this holiday season.<br />
Finally, on behalf of all of us at <strong>Spectroscopy</strong>, I would like to take this opportunity to wish all<br />
of our readers and their families Happy Holidays and a Happy New Year. I think we can agree<br />
that all of life’s problems and challenges pale in comparison to the joy of celebrating the holidays<br />
with family and friends.<br />
David Walsh<br />
Editor-in-Chief<br />
David.Walsh@advanstar.com
www.spectroscopyonline.com<br />
News Spectrum<br />
Research<br />
Researchers at several different locations of the National<br />
Institute of Health (Bethesda, Maryland) have<br />
combined to perform a neuroimaging study of brain<br />
development in healthy, normally developing children<br />
from birth to young adulthood. The latest data released<br />
by the group include longitudinal imaging and clinical/<br />
behavioral data for children ages seven days to four years<br />
old.<br />
Here, MRI scan data are accompanied by corresponding<br />
data from physical neurological examinations, behavioral<br />
ratings, neuropsychological testing, structured psychiatric<br />
interviews, and hormonal measures from urine and saliva<br />
samples. This is the first release to include data from a<br />
technique called MR spectroscopy, a type of MRI scan that<br />
measures the levels of certain by-products of metabolism<br />
that can be used to gauge the health of brain tissues.<br />
It is hoped that raw data sharing such as this will help to<br />
optimize the burgeoning knowledge of conditions such as<br />
autism, among others. Accordingly, databases are being<br />
created in certain rapidly growing fields. Judith Rumsey,<br />
National Institute of Mental Health, explained: “These<br />
data-sharing efforts reflect a new approach to science.<br />
The database can be used to chart normal developmental<br />
trajectories in order to identify deviations in milestones<br />
associated with disease.”<br />
December 2009 <strong>Spectroscopy</strong> 24(12) 11<br />
Scientists with the Foundation for Scientific and<br />
Industrial Research (Trondheim, Norway) have<br />
developed a solution to sorting waste for recycling based<br />
upon infrared spectroscopy. Using halogen lamps as light<br />
sources, an instrument has been developed that can<br />
distinguish between plastic-coated cardboard, ordinary<br />
cardboard, and different kinds of plastics by small<br />
variations in the color of the reflected infrared light. In<br />
the selected range of infrared wavelengths, objects have<br />
different reflection properties than for ordinary visible<br />
light.<br />
Industry<br />
HORIBA (Edison, New Jersey) has received an order<br />
from the United States National Aeronautics and<br />
Space Administration (NASA, Washington, DC) to<br />
supply water quality sensors to be used in their medical<br />
intravenous (IV) fluid production device.<br />
IV fluid is essential for medical treatment and surgical<br />
procedures, and must be available at the International<br />
Space Station (ISS) for future long-duration exploration<br />
missions. It is impossible to deliver enough fresh IV fluid<br />
from the earth to the ISS. Therefore, NASA is developing<br />
an IVGEN (Intra Venous GENeration) system, which<br />
reuses the feedstock water in ISS to a purity level of<br />
pharmaceutical standards.<br />
Market Profile: Process FT-NIR<br />
Mass Fourier spectrometry transform–near (MS) infrared is a broadly (FT-NIR) used analytical spectroscopy<br />
technique is one of a that number is often molecular combined spectroscopy with some form techniques<br />
that are already to provide used a for second online dimension process analysis of<br />
of<br />
chromatography<br />
separation. across a number However, of industries, vendors recently but are still have seeing begun significant<br />
growth ion in mobility demand. separation FT-NIR technology (IMS) into has high-<br />
a<br />
incorporating<br />
end number LC–MS of inherent instruments, advantages thus providing for online analysis. additional<br />
level The combination of ion separation. of the FT<br />
analysis method and the<br />
NIR spectrum combine to<br />
Other (8%)<br />
make FT-NIR a very useful<br />
online analytical tool.<br />
Biofuels (7%)<br />
Pharmaceuticals (17%)<br />
The use of the FT technique<br />
allows for instantaneous<br />
analysis of the entire<br />
spectrum of a broadband<br />
light source, rather than<br />
Chemicals (21%)<br />
having to scan across the<br />
spectrum of interest or use<br />
only a single point of the<br />
electromagnetic spectrum<br />
for analysis. This is ideal for providing detailed analytical<br />
information of continuously flowing or changing<br />
processes. Although not as sensitive as mid-IR<br />
Process FT-NIR demand by industry in 2009.<br />
spectroscopy, NIR spectroscopy allows for deeper penetration<br />
of the sample, and is better for bulk materials.<br />
Online FT-NIR is used most heavily in refineries and<br />
general chemical facilities due to its strength in the<br />
analysis of petrochemical compounds. A rapidly growing<br />
niche is in the development of alternative<br />
biofuels. The global market<br />
for process FT-NIR is well<br />
over $20 million annually,<br />
and is expected to see midto-high<br />
single-digit growth.<br />
Petroleum (47%)<br />
The foregoing data was based<br />
upon SDi’s Market Analysis<br />
& Perspectives (MAP)<br />
report program. For more<br />
information, contact Stuart<br />
Press, Senior Consultant,<br />
Strategic Directions<br />
International, Inc., 6242<br />
Westchester Parkway, Suite<br />
100, Los Angeles, CA 90045, (310) 641-4982, fax:<br />
(310) 641-8851, www.strategic-directions.com.
12 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009<br />
ABB Analytical<br />
www.spectroscopyonline.com<br />
ABB Analytical<br />
585 boul. Charest E.<br />
suite 300<br />
Quebec, QC<br />
G1K 9H4<br />
Canada<br />
TELEPHONE<br />
(418) 877-2944<br />
FAX<br />
(418) 877-2834<br />
E-MAIL<br />
ftir@ca.abb.com<br />
WEB SITE<br />
www.abb.com/analytical<br />
NUMBER OF EMPLOYEES<br />
200<br />
YEAR FOUNDED<br />
1973<br />
Company Description<br />
Founded in 1973 as Bomem Inc., the Analytical Business<br />
Unit of ABB enables scientists around the world to perform<br />
through excellence in infrared spectroscopy. ABB is a market<br />
leader in Fourier Transform Infrared (FT-IR and FT-NIR) in<br />
terms of reliability and reproducibility. ABB Analytical designs,<br />
manufactures, and markets high-performance, affordable<br />
spectrometers as well as turnkey analytical solutions and<br />
spectroradiometers for remote sensing. ABB Analytical capabilities<br />
encompass one of the largest portfolios in the world<br />
for laboratory, at-line, and process FT-IR analyzers. They perform<br />
real-time analysis of the chemical composition and/or<br />
physical properties of a process sample stream.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
FT-IR<br />
FT-NIR<br />
Spectroradiometry and Remote Sensing<br />
Dedicated team of engineers offering simple and<br />
dependable solutions with reliable instruments<br />
Local point of contact for field service and technical<br />
support in most countries around the world with<br />
inventories for parts on all continents<br />
Markets Served<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Laboratory and Academic<br />
Life Sciences<br />
Pharmaceutical<br />
Fine Chemicals, Specialty Chemicals, and Commodity<br />
Chemicals<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Refining and Petrochemicals<br />
Metallurgical<br />
Semiconductor<br />
Original Equipment Manufacturer (OEM)<br />
Remote Sensing and Aerospace<br />
Major Products/Services<br />
ABB’s advanced solutions combine<br />
analyzers, advanced process control, data<br />
management, and process and application<br />
knowledge to improve the operational<br />
performance, productivity, capacity, and<br />
safety of industrial processes for customers.<br />
For all laboratory or process needs, ABB<br />
can be your partner and single-source<br />
provider of simple, low-cost, high performance,<br />
general-purpose FT-IR and FT-NIR<br />
spectrometers. The company also markets<br />
analyzers for hydrogen and inclusion<br />
measurement in liquid aluminum.<br />
Facility<br />
Our manufacturing facility located in<br />
Quebec City, Canada, employs more than<br />
200 people, including R&D, manufacturing,<br />
marketing, sales, and administrative<br />
groups. The ABB Group of companies<br />
operates in around 100 countries and<br />
employs about 120,000 people.
14 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
Amptek, Inc.<br />
instrument is ideal for both the laboratory<br />
and OEM industries.<br />
Completing Amptek’s XRF portable<br />
solutions for exact measurements are the<br />
new, USB-controlled Mini-X X-ray tube and<br />
the XRF-FP Quantitative Analysis Software.<br />
Please visit our web site for complete<br />
specifications.<br />
Amptek, Inc.<br />
14 DeAngelo Drive<br />
Bedford, MA 01730<br />
TELEPHONE<br />
(781) 275-2242<br />
FAX<br />
(781) 275-3470<br />
E-MAIL<br />
sales@amptek.com<br />
WEB SITE<br />
www.amptek.com<br />
NUMBER OF EMPLOYEES<br />
29<br />
YEAR FOUNDED<br />
1977<br />
Company Description<br />
Amptek, Inc. is a recognized world leader in the design and<br />
manufacture of state-of-the-art X-ray and gamma ray detectors,<br />
preamplifiers, instrumentation and components for<br />
portable instruments, laboratories, satellites, and analytical<br />
purposes. These products provide the user with high performance<br />
and high reliability together with small size and low<br />
power.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
X-ray fluorescence (EDXRF)<br />
Direct spectral measurements<br />
SEM<br />
PIXE<br />
TXRF<br />
Markets Served<br />
Amptek serves wherever X-ray detection is used; for example,<br />
hand-held and table-top XRF analyzers produced by OEMs;<br />
research facilities in universities, commercial enterprises and<br />
the military; nuclear medicine; space; museums; environmental<br />
monitoring; and geological analysis of soils and minerals.<br />
Major Products/Services<br />
Models XR-100CR and XR-100SDD are high-performance<br />
X-ray detector systems using a thermoelectric cooler and no<br />
liquid nitrogen, featuring a wide range of detection areas and<br />
efficiency and resolution of 129 eV FWHM. Power and shaping<br />
are provided by the PX4 Digital Pulse Processor. The<br />
XR-100 successfully analyzed the rocks and soil on Mars.<br />
The X-123 is a complete X-ray detector system in one small<br />
box that fits in your hand. The X-123 incorporates either the<br />
Amptek Si-Pin Diode Detector or Silicon Drift detector (SDD);<br />
Charge Sensitive Preamplifier; the Amptek DP5 Digital Pulse<br />
Processor and MCA; and the Amptek PC5 Power Supply. This<br />
small, low power, easy to operate, high-performance<br />
Applications<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
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⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
X-Ray Fluorescence<br />
Process Control<br />
OEM Instrumentation<br />
RoHS/WEEE Compliance Testing<br />
Nondestructive Analysis with XRF<br />
Restricted Metals Detection<br />
Environmental Monitoring<br />
Medical and Nuclear Electronics<br />
Heavy Metals in Plastics<br />
Lead Detectors<br />
Toxic Dump Site Monitoring<br />
Semiconductor Processing<br />
Nuclear Safeguards Verification<br />
Plastic & Metal Separation<br />
Coal & Mining Operations<br />
Sulfur in Oil and Coal Detection<br />
Smoke Stack Analysis<br />
Plating Thickness<br />
Oil Logging<br />
Electro-Optical Systems<br />
Research Experiments & Teaching<br />
Art and Archaeology<br />
Jewelry Analysis
16 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
Applied Photophysics<br />
Applied Photophysics<br />
203–205 Kingston Road<br />
Leatherhead<br />
Surrey KT22 7PB<br />
United Kingdom<br />
TELEPHONE<br />
UK +44 (0)1372 386537<br />
Toll-Free (from USA only)<br />
1-800 543 4130<br />
E-MAIL<br />
Sales Department:<br />
sales@photophysics.com<br />
Technical Support:<br />
techsup@photophysics.com<br />
WEB SITE<br />
www.photophysics.com<br />
YEAR FOUNDED<br />
1971<br />
Company Description<br />
Applied Photophysics is a world-leading manufacturer and<br />
supplier of precision spectrometers to researchers working in<br />
pharmaceutical, biotechnology, and academic environments.<br />
Our instruments are used to determine structural, thermodynamic,<br />
and kinetics properties of a wide range of samples in<br />
solution. Established in 1971, Applied Photophysics has an<br />
enviable reputation for outstanding performance and<br />
innovative technology.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
Circular dichroism (CD) spectroscopy<br />
Stopped-flow spectroscopy<br />
Laser-flash photolysis spectroscopy<br />
Markets Served<br />
Applied Photophysics offers precision spectrometers to academic<br />
and industrial markets. The Chirascan spectrometers<br />
are now the CD instruments of choice in pharmaceutical and<br />
biotechnology markets for use in drug development, formulation<br />
testing, biocomparability studies, and quality control. The<br />
SX20 and LKS.60 spectrometers are established leaders for<br />
stopped-flow and laser-flash research in the academic market,<br />
addressing applications in protein structure, folding, and conformation,<br />
together with biomolecular reaction kinetics and<br />
the study of chemical reaction mechanisms.<br />
Major Products/Services<br />
Chirascan and Chirascan-plus circular dichroism<br />
spectrometers (CD)<br />
Outstanding sensitivity, novel detection techniques, and powerful<br />
software combine to establish these instruments as the<br />
world’s most advanced CD spectrometers.<br />
SX20 stopped-flow spectrometer<br />
The SX20 is the market-leading stoppedflow<br />
reaction analyzer capable of measuring<br />
fast reactions with a minimum of<br />
material.<br />
LKS.60 nanosecond laser-flash<br />
photolysis spectrometer<br />
The LKS.60 offers unmatched sensitivity<br />
for single and multiwavelength kinetics of<br />
very short-lived species, such as free radicals<br />
and excited-state species.<br />
RX.2000 rapid mixing stopped-flow<br />
unit<br />
Adds stopped-flow rapid reaction kinetics<br />
to any UV-visible spectrometer or<br />
fluorometer.<br />
Pro-Data software<br />
Stopped-flow and circular dichroism spectrometers<br />
incorporate common software<br />
enabling cross-platform compatibility.<br />
Accessories<br />
With all products, a wide range of accessories<br />
is available to expand the system as<br />
research interests evolve.<br />
Customer Support<br />
Support is provided for the lifetime of the<br />
product and every instrument comes with<br />
a warranty of at least 12 months that can<br />
be easily extended. A world-class service<br />
team is on hand for support and applications<br />
advice.<br />
Facilities<br />
Headquartered close to London, UK. See<br />
www.photophysics.com/agents.php for<br />
worldwide distribution network.
18 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
Andor Technology plc<br />
semiconductors), chemical analysis, and<br />
astronomy, as well as industrial applications<br />
such as food and safety, process<br />
control, drug screening, forensic, environment/water<br />
monitoring, and solar panel<br />
inspection.<br />
Andor Technology plc<br />
7 Millennium Way<br />
Springvale Business Park<br />
Belfast BT12 7AL,<br />
United Kingdom<br />
TELEPHONE<br />
International Free Phone:<br />
+ 800 9027 0899<br />
UK: + 44 (0)28 9023 7126<br />
US: (800) 296-1579<br />
FAX<br />
+ 44 (0)28 9031 0792<br />
E-MAIL<br />
marketing@andor.com<br />
WEB SITE<br />
www.andor.com<br />
NUMBER OF EMPLOYEES<br />
USA: 25<br />
Elsewhere: 189<br />
YEAR FOUNDED<br />
1989<br />
Company Description<br />
Andor Technology plc (Andor) is a world leading manufacturer<br />
of high performance modular spectroscopy detection<br />
solutions. Based around best-in-class, research grade CCDs,<br />
exclusive Electron Multiplying CCDs, and Intensified CCD detectors,<br />
as well as seamlessly configurable spectrometers and<br />
dedicated spectroscopy software, Andor’s robust detection<br />
solutions offer a unique combination of sensitivity, speed, and<br />
ease-of-use. Andor’s core technology Ultravac, combines<br />
thermo-electric cooling and vacuum sealing, guaranteeing<br />
sustained detector performance year after year. Andor is also<br />
involved in numerous collaborations with academic<br />
institutions worldwide.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
UV-VIS-NIR Optical Emission <strong>Spectroscopy</strong><br />
Raman (Pulsed, Resonance, SERS, SORS, CARS, TERS, TR 3 )<br />
Fluorescence / Photoluminescence<br />
Plasma studies<br />
Laser Induced Breakdown <strong>Spectroscopy</strong> (LIBS)<br />
Micro-<strong>Spectroscopy</strong><br />
Absorption/Transmission/Reflection (ATR)<br />
Hyper-spectral Imaging<br />
Light Detection and Ranging (LIDAR)<br />
X-Ray Diffraction and Fluorescence (XRD/XRF)<br />
Markets Served<br />
In the analytical and life sciences markets Andor products<br />
are particularly suited to fundamental research in the field of<br />
biology, nanotechnology, material characterization (polymers,<br />
Major Products/Services<br />
Andor’s spectroscopy range features a<br />
high performance CCD platform (Newton)<br />
with exclusive dedicated <strong>Spectroscopy</strong><br />
EMCCD for rapid, light-starved applications.<br />
Andor’s most popular CCD/InGaAs<br />
platform is the iDUS, for all general<br />
<strong>Spectroscopy</strong> applications, alongside the<br />
market leading ICCD camera, iStar, for ns<br />
gated applications. The Shamrock family<br />
is Andor’s versatile spectrometer platform,<br />
with USB connectivity and seamless<br />
configuration with a wide range of accessories,<br />
including fiber optics bundles, and<br />
interface to microscopes. Solis software<br />
boasts a dedicated interface, integrating<br />
data acquisition and cameras/spectrometers<br />
simultaneous control. Andor’s X-Ray<br />
detector range features a wide range of<br />
Direct/Indirect detection options on the<br />
Newton and iKon platform.
www.spectroscopyonline.com<br />
Avantes, Inc.<br />
DECEMBER 2009 SPECTROSCOPY CORPORATE CAPABILITIES 19<br />
Avantes, Inc.<br />
9769 W 119th Ave, Suite 4<br />
Broomfield, CO 80021<br />
TELEPHONE<br />
(303) 410-8668<br />
FAX<br />
(303) 410-8669<br />
E-MAIL<br />
infoUSA@avantes.com<br />
NUMBER OF EMPLOYEES<br />
40<br />
YEAR FOUNDED<br />
1993<br />
Company Description<br />
Avantes is a leading innovator<br />
in the development and<br />
application of miniature<br />
spectrometers. Avantes<br />
continues to develop and introduce<br />
new instruments for<br />
Fiber Optic <strong>Spectroscopy</strong> to<br />
meet our customer’s application<br />
needs. Avantes instruments<br />
and accessories are<br />
also deployed into a variety<br />
of OEM applications in a variety<br />
of industries in markets throughout the world. With more<br />
than 15 years of experience in Fiber Optic <strong>Spectroscopy</strong> and<br />
thousands of instruments in the field, Avantes is eager to help<br />
our customers find their Solutions in <strong>Spectroscopy</strong>®.<br />
Chief Spectroscopic Techniques Supported<br />
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⦁<br />
⦁<br />
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UV–VIS/NIR <strong>Spectroscopy</strong><br />
Process Control<br />
Raman <strong>Spectroscopy</strong><br />
Absorbance/Transmittance/Reflectance<br />
Laser-Induced Breakdown <strong>Spectroscopy</strong><br />
CIE Color <strong>Spectroscopy</strong><br />
Portable Spectrophotometers<br />
Fluorescence <strong>Spectroscopy</strong><br />
Custom Applications<br />
Irradiance<br />
OEM Application Development<br />
Markets Served<br />
Avantes works with customers in a variety of markets, including<br />
chemical, biomedical, aerospace, semiconductor, gemological,<br />
paper, pharmaceutical, and food processing technology.<br />
Additionally, Avantes works with research organizations<br />
and universities, aiding in developing research and teaching<br />
opportunities. Our OEM program is designed to work with our<br />
customers to identify needs and customize an Avantes’ spectroscopy<br />
solution based our customer’s needs and Avantes<br />
technical know experience. Avantes’ continued growth is<br />
based upon a commitment to providing exceptional technology<br />
and superb customer satisfaction.<br />
Major Products/Services<br />
⦁<br />
Low-cost, high-resolution, miniature fiber optic spectrometers:<br />
System solutions and OEM instruments for<br />
applications from 185 nm to 2,500 nm. Detector choices:<br />
PDA, CMOS, CCD, back-thinned CCD, and InGaAs. Optical<br />
⦁<br />
⦁<br />
⦁<br />
benches with focal lengths of 45, 50 or<br />
75 mm and a revolutionary new straylight<br />
reduction optimized optical bench<br />
(ULS). Other features: 14 and 16 bit<br />
A/D converters, TE cooling, multi-channel<br />
instrument configurations enabling<br />
simultaneous signal acquisition, USB2<br />
communication, support for multiple instruments<br />
from a single computer, and<br />
14 programmable digital I/O ports.<br />
Standard Application Solutions: Raman<br />
<strong>Spectroscopy</strong>, Gemology, Oxygen Sensing,<br />
Chemometric Analysis, Thin-Film<br />
Measurement, Color, Fluorescence, Laser-Induced<br />
Breakdown <strong>Spectroscopy</strong>,<br />
Irradiance and LED measurements, and<br />
Process Control.<br />
Light Sources: Tungsten-halogen, Deuterium,<br />
LED, Xenon, Calibration sources<br />
for wavelength and irradiance.<br />
<strong>Spectroscopy</strong> Accessories: Fiber optic<br />
cables and probes, integrating spheres,<br />
cuvette holders, flow cells, collimating<br />
lenses, cosine correctors, vacuum feedthroughs,<br />
fiber optic multiplexer.<br />
Facilities<br />
Avantes engineering manufacturing, sales,<br />
and service headquarters is in the Netherlands.<br />
The company also operates direct<br />
offices in China and North America. In addition,<br />
Avantes has a growing worldwide<br />
distribution network of more than 35<br />
qualified distributors to meet our customers’<br />
needs worldwide.
20 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009<br />
B&W Tek, Inc.<br />
www.spectroscopyonline.com<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Portable Raman and<br />
fluorescence instruments<br />
Process Raman, UV, visible,<br />
and NIR analyzers<br />
Broadband superluminescent<br />
light sources<br />
High power turn-key<br />
diode laser systems<br />
Low noise lasers, DPSS lasers,<br />
diode lasers, and fiber lasers<br />
Confocal Microscope<br />
Facilities<br />
Three facilities in the US and three<br />
facilities in international locations.<br />
Company Description<br />
B&W Tek is an advanced instrumentation company producing<br />
optical spectroscopy and laser instruments for biomedical,<br />
physical, chemical, and research communities. With a strong<br />
vertical integration capability, B&W Tek also provides custom<br />
product development, design, and manufacturing.<br />
B&W Tek, Inc.<br />
19 Shea Way<br />
Newark, DE 19713<br />
TELEPHONE<br />
(302) 368-7824<br />
FAX<br />
(302) 368-7830<br />
E-MAIL<br />
info@bwtek.com<br />
WEB SITE<br />
www.bwtek.com<br />
NUMBER OF EMPLOYEES<br />
USA: 100<br />
Elsewhere: 100<br />
YEAR FOUNDED<br />
1997<br />
Chief Spectroscopic Techniques Supported<br />
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UV<br />
Visible<br />
NIR<br />
Raman<br />
Laser<br />
Microscopy<br />
Markets Served<br />
B&W Tek’s OED and OEM services provide innovative solutions<br />
for the design, development, and quality manufacturing<br />
to the most demanding requirements for analytical, industrial,<br />
medical, biophotonic, and diagnostic applications. Markets<br />
include industries, universities, research labs, oil and refining<br />
facilities, paper production, optical products manufacturers,<br />
drug and agricultural, health care, process analysis, gemological<br />
R&D, etc.<br />
Major Products/Services<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Customized design and development services<br />
Customized photonic instrumentation manufacturing<br />
End User and OEM spectrometer and laser products<br />
UV/Visible and NIR array spectrophotometer systems
22 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
BaySpec, Inc.<br />
Markets Served<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
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Biomedical<br />
Pharmaceuticals<br />
Chemical<br />
Food<br />
Semiconductor<br />
Industrial controls<br />
Homeland security<br />
Fiber sensing<br />
Optical telecommunications<br />
Major Products/Services<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
UV-VIS-NIR spectrographs and spectrometers<br />
Handheld/Portable/Benchtop Raman<br />
Instruments<br />
Narrowband and Wideband Light<br />
Sources<br />
Fiber Optic Probes<br />
Fiber Optic Accessories<br />
BaySpec, Inc.<br />
101 Hammond Avenue<br />
Fremont, CA 94539<br />
TELEPHONE<br />
(510) 661-2008<br />
FAX<br />
(510) 661-2009<br />
E-MAIL<br />
sales@bayspec.com<br />
WEB SITE<br />
www.bayspec.com<br />
NUMBER OF EMPLOYEES<br />
USA: 50-100<br />
YEAR FOUNDED<br />
1999<br />
Company Description<br />
BaySpec, Inc., founded in 1999 with 100% manufacturing in<br />
the USA (Fremont, California), is a vertically integrated spectral<br />
sensing company. The company designs, manufactures,<br />
and markets advanced spectral instruments, from UV-VIS-NIR<br />
spectrometers to handheld and portable NIR and Raman<br />
analyzers for a diverse customer base around the world.<br />
The telecommunication market “boom and bust” has produced<br />
an array of components and technologies, which collectively<br />
for the first time in instrumentation history, realized<br />
the dream of a low-cost yet highly accurate spectral device.<br />
Out of the ashes comes new growth. Stemming from Bay-<br />
Spec’s revolutionary Volume Phase Gratings (VPG(®)) -based<br />
telecom modules, customers in optical test & measurement,<br />
fiber sensing, UV-VIS-NIR and Raman spectroscopy, are benefiting<br />
and building innovative systems to meet the world’s<br />
most current optical system challenges.<br />
While our customer base already spans from the traditional<br />
areas of optical telecommunication and NIR spectroscopy,<br />
we are changing and revolutionizing the way of Raman, Fluorescence,<br />
absorption/reflection, handheld, and OCT spectroscopic<br />
instruments are applied.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
UV-VIS-NIR specroscopy<br />
Raman spectroscopy<br />
Facilities<br />
22,000 sq ft facility in Fremont, California<br />
(Silicon Valley).
www.spectroscopyonline.com<br />
Bruker Corporation<br />
DECEMBER 2009 SPECTROSCOPY CORPORATE CAPABILITIES 23<br />
Bruker Corporation<br />
40 Manning Road<br />
Billerica, MA 01821<br />
TELEPHONE<br />
(978) 663-3660<br />
FAX<br />
(978) 667-5993<br />
E-MAIL<br />
info@bruker.com<br />
WEB SITE<br />
www.bruker.com<br />
Company Description<br />
Right from the beginning, which is now fifty years ago, Bruker<br />
has been driven by a single idea: to provide the best technological<br />
solution for each analytical task. Today, more than<br />
4000 employees worldwide are working on this permanent<br />
challenge at over 90 locations on all continents. Bruker<br />
systems cover a broad spectrum of applications in all fields<br />
of research and development and are used in all industrial<br />
production processes for the purpose of ensuring quality and<br />
process reliability.<br />
Bruker continues to build upon its extensive range of products<br />
and solutions, its broad base of installed systems and<br />
a strong reputation amongst its customers. Indeed, as our<br />
customers would expect, Bruker as one of the world’s leading<br />
analytical instrumentation companies, continues to develop<br />
state-of-the-art technologies and innovative solutions for<br />
today’s analytical questions.<br />
Chief Spectroscopic Techniques<br />
Supported<br />
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⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Atomic Force Microscopy<br />
Combustion Analysis<br />
EPR <strong>Spectroscopy</strong><br />
Fourier Transform Infrared <strong>Spectroscopy</strong><br />
and Microscopy (FT-IR)<br />
Fourier Transform Mass Spectrometry<br />
(FT-MS)<br />
Fourier Transform Near Infrared<br />
<strong>Spectroscopy</strong> (FT-NIR)<br />
Handheld X-ray (XRF) Spectrometers<br />
Ion Mobility Spectrometry<br />
Ion Trap Mass Spectrometry<br />
Low Resolution Benchtop<br />
NMR Analyzers<br />
Magnetic Resonance Imaging (MRI)<br />
MALDI-TOF (/TOF) Mass Spectrometry<br />
Mass Spectrometry (LC-MS)<br />
NMR <strong>Spectroscopy</strong><br />
Optical Emission <strong>Spectroscopy</strong><br />
(Spark-OES)<br />
Portable Mass Spectrometers (GC–MS)<br />
Raman <strong>Spectroscopy</strong> and Microscopy<br />
Terahertz <strong>Spectroscopy</strong> and Imaging<br />
X-ray Crystallography<br />
X-ray Diffraction (XRD)<br />
X-ray Fluorescence (XRF)<br />
X-ray Microanalysis (EDS, EBSD)
24 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
EDAX, Inc.<br />
academic, and industrial R&D laboratories,<br />
ROHS/WEEE, renewable energy, pharmaceuticals,<br />
mining, security, forensics,<br />
catalysts, petrochemicals, metallurgy, and<br />
manufacturing operations.<br />
EDAX, Inc.<br />
91 McKee Drive<br />
Mahwah, NJ 07430<br />
TELEPHONE<br />
(201) 529-4880<br />
FAX<br />
(201) 529-3156<br />
E-MAIL<br />
info.edax@ametek.com<br />
WEB SITE<br />
www.edax.com<br />
YEAR FOUNDED<br />
1962<br />
Company Description<br />
EDAX Inc is an ISO-9001 certified manufacturer with over 45<br />
years of experience building instrumentation for the elemental<br />
and structural analysis of materials. EDAX’s founding technology<br />
was the detection and measurement of fluorescent<br />
X-rays for qualitative and quantitative elemental analysis — for<br />
example, elemental analysis on electron beam microscopes.<br />
Since that time, EDAX has sought to expand our product offering<br />
through new technologies and complementary techniques<br />
to provide our customers with the latest analytical instrumentation<br />
available. EDAX continues to be the world leader in the<br />
X-ray microanalysis market while providing new products for<br />
micro X-ray fluorescence and electron backscatter diffraction.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Energy Dispersive <strong>Spectroscopy</strong><br />
Energy Dispersive X-ray Fluorescence<br />
Electron Back Scatter Diffraction<br />
Wavelength Dispersive <strong>Spectroscopy</strong><br />
Markets Served<br />
EDAX instrumentation for elemental and structural analysis is<br />
found in a broad spectrum of industrial, academic, and<br />
government applications from the field or warehouse to the<br />
most advanced research & development laboratory. Typical<br />
markets served include semiconductor and microelectronics,<br />
Major Products/Services<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Energy Dispersive X-ray Fluorescence:<br />
EDAX manufactures micro XRF<br />
analyzers for the laboratory.<br />
Electron BackScatter Diffraction:<br />
EDAX supplies instrumentation for<br />
materials structural analysis on SEM<br />
electron-beam microscopes.<br />
Energy Dispersive <strong>Spectroscopy</strong>:<br />
EDAX provides a full range of EDS<br />
products for elemental analysis on SEM<br />
and TEM electron-beam microscopes.<br />
Wavelength Dispersive <strong>Spectroscopy</strong>:<br />
EDAX offers parallel beam WDS<br />
products for elemental analysis on<br />
SEM electron-beam microscopes.<br />
Fluorescent X-ray Detectors: EDAX supplies<br />
Si(Li) Detectors and Silicon Drift<br />
Detectors, which are capable of<br />
handling count rates of over<br />
1,000,000 cps and parallel beam<br />
wavelength dispersive spectrometers.<br />
Facilities<br />
EDAX headquarters is located in Mahwah,<br />
New Jersey, housing sales, technical<br />
support and manufacturing operations.<br />
EDAX is committed to providing the best<br />
possible support for our customers worldwide<br />
with sales, service, and applications<br />
support offices located in Japan, China,<br />
Singapore, The Netherlands, Germany, UK,<br />
and the United States.
26 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
CVI Melles Griot<br />
CVI Melles Griot<br />
Lasers<br />
2051 Palomar Airport Road, 200<br />
Carlsbad, CA 92011<br />
TELEPHONE<br />
(760) 438-2131<br />
E-MAIL<br />
lasers@cvimellesgriot.com<br />
CVI Melles Griot<br />
Optics & Assemblies:<br />
200 Dorado Place SE<br />
Albuquerque, NM 87123<br />
TELEPHONE<br />
(505) 296-9541<br />
E-MAIL<br />
optics@cvimellesgriot.com<br />
WEB SITE<br />
www.cvimellesgriot.com<br />
ASIA<br />
+81 3 3407-3614<br />
EUROPE<br />
+31 316 333 041<br />
Company Description<br />
CVI Melles Griot is a leading global<br />
supplier of OEM and fast turn catalog<br />
photonics products including lasers at<br />
over 38 wavelengths, optics, coatings<br />
covering the deep ultraviolet to the<br />
infrared, opto-mechanics, and positioning<br />
equipment. The company’s unique<br />
breadth of manufacturing and design<br />
expertise in electronics, lasers, optics, coatings, and thermal<br />
management is evident in everything from simple components<br />
to precision integrated electro-optic assemblies.<br />
Chief Spectroscopic Techniques Supported<br />
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⦁<br />
⦁<br />
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⦁<br />
<strong>Spectroscopy</strong>; Microscopy<br />
Capillary electrophoresis<br />
Biotech/Medical<br />
Laser-induced fluorescence<br />
Pharmaceutical<br />
Particle characterization<br />
Semiconductor<br />
Non-contact inspection<br />
Industrial<br />
Interferometry<br />
Environmental<br />
Velocimetry<br />
Government/Military<br />
Markets Served<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Design, development, and manufacturing on 3 continents<br />
Lasers, optics, thin films, mechanics, drive electronics<br />
Over 39 years of volume production<br />
Over 2.9 million lasers and 120 million optics shipped<br />
www.spectroscopyonline.com DECEMBER 2009 SPECTROSCOPY CORPORATE CAPABILITIES 27<br />
Fiberguide Industries, Inc.<br />
Major Products/Services<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Optical Fibers<br />
Multimode: 50 μm ~ 2000 μm Core<br />
(Silica and Hard Clad)<br />
Single Mode: 633 nm and 1550 nm<br />
Polyimide, Nylon, Tefzel, Acrylate, Hard<br />
Clad Buffers<br />
Sterilizeable: ETO, Steam, E-beam,<br />
Gamma<br />
All Material Certified to USP Class VI<br />
Biocompatibility<br />
All Materials RoHS Compliant<br />
Custom Bundles and Assemblies<br />
High Power Laser Delivery<br />
Collimators and Focus Guides<br />
Fiberguide Industries, Inc.<br />
1 Bay Street<br />
Stirling, NJ 07980<br />
TELEPHONE<br />
(908) 647-6601<br />
FAX<br />
(908) 647-8464<br />
E-MAIL<br />
info@fiberguide.com<br />
WEB SITE<br />
www.fiberguide.com<br />
NUMBER OF EMPLOYEES<br />
67<br />
YEAR FOUNDED<br />
1977<br />
Company Description<br />
Support OEM’s worldwide in taking concepts and ideas to<br />
market with line of multimode, single mode, and graded<br />
index optical fibers from UV-IR, and temperature ranges from<br />
−269 ∘C to 700 ∘C. Design/engineer assemblies using not<br />
only our own pure silica core/silica clad, silica core/plastic<br />
clad fibers, but borosilicate glass fiber, ESKA plastic optical<br />
fiber, fluoride fiber, chalcogenide fiber, erbium-doped fiber,<br />
and polarization maintaining fiber as well, with widest range<br />
of custom and standard endfittings/connectors and outer<br />
jackets to tailor a product to technical and economic requisites.<br />
Design/manufacture of ultra precision high density 2D<br />
arrays, V-Groove arrays designed for optical switches, WDM/<br />
DWDM, and arrayed active devices; and reflection/backscattering<br />
probes for measuring specular or diffuse reflection from<br />
a surface. FDA registered as a Contract Manufacturer.<br />
Chief Spectroscopic Techniques Supported<br />
All optical fiber–based assemblies for Mass Spectrometry,<br />
ICP-MS, Infrared, FT-IR, UV-VIS, Raman, NMR, X-ray, and<br />
Fluorescence.<br />
Markets Served<br />
Lifes Sciences, <strong>Spectroscopy</strong>/Instrumentation, Laser, Defense/<br />
Military, Semiconductor/Wafer Processing, Industrial, and<br />
Academic.<br />
Facilities<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
NJ — 10,000 square feet with fiber<br />
draw capacity up to 150 km fiber/day.<br />
ID — 28,000 square feet vertically integrated<br />
engineering and manufacturing.<br />
FDA QSR Registered<br />
ISO9001:2008 compliant<br />
Class 10,000 assembly areas<br />
OEM cables and assemblies
28 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
FOSS NIRSystems, Inc.<br />
⦁<br />
⦁<br />
Reaction monitoring<br />
Endpoint determination.<br />
FOSS NIRSystems, Inc.<br />
7703 Montpelier Road<br />
Laurel, MD 20723<br />
TELEPHONE<br />
(301) 680-9600<br />
FAX<br />
(301) 236-0134<br />
E-MAIL<br />
info@foss-nirsystems.com<br />
WEB SITE<br />
www.foss-nirsystems.com<br />
NUMBER OF EMPLOYEES<br />
USA: 100<br />
Elsewhere: 1200<br />
YEAR FOUNDED<br />
1956<br />
Company Description<br />
FOSS NIRSystems, Inc. is a unit of FOSS A/S and the world’s<br />
leading supplier of laboratory, at-line, and process nearinfrared<br />
(NIR) solutions. FOSS NIRSystems has more than<br />
40 years of industry experience and over 18,000 successful<br />
installations worldwide. As a strategic partner to the world’s<br />
major pharmaceutical, chemical, and petrochemical companies,<br />
FOSS is committed to providing the most accurate and<br />
precise rapid test and measurement products to meet our<br />
customer’s needs.<br />
FOSS’ global distribution and support network ensure<br />
consistent product and application knowledge and superior<br />
customer technical support and training in over 65 countries<br />
worldwide. Our customers are provided with the most integrated<br />
and tested solutions including hardware, software,<br />
method development, and documentation. Following the<br />
Good Automated Manufactured Practice (GAMP), FOSS<br />
created Vision to cover both the software and hardware<br />
compliance elements of 21 CFR Part 11.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
Near-Infrared <strong>Spectroscopy</strong> (NIR)<br />
Markets Served<br />
We provide laboratory, at-line, and process near-infrared (NIR)<br />
solutions for use in the pharmaceutical, chemical, petrochemical,<br />
and related industries. Applications include:<br />
⦁<br />
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Raw material inspection<br />
Inspection of solids, powders and liquids<br />
Content uniformity of solid dosage forms<br />
Blending, mixing, granulation, and drying processes<br />
Major Products/Services<br />
As a Process Analytical Technology (PAT)<br />
tool, the XDS NIR Analyzer is the next<br />
generation of dedicated NIR technology<br />
for analyzing solid and liquid chemical<br />
and pharmaceutical formulations. The<br />
patented design of XDS NIR offers superior<br />
analytical performance with increased sensitivity<br />
and precise instrument matching to<br />
enhance method development, minimize<br />
implementation time and ensure seamless<br />
method transferability. XDS NIR analyzers<br />
can be used throughout your manufacturing<br />
processes – from raw material<br />
inspection and in-process testing to final<br />
product release. XDS NIR analyzers feature<br />
hot-swappable sample modules for easeof-use<br />
and sampling flexibility that can<br />
be used in both the laboratory and plant<br />
environments. Process XDS NIR analyzers<br />
are available in single and multiple point<br />
configurations, meeting most electrical<br />
area classifications. XDS NIR brings new<br />
levels of reliability, versatility, and efficiency<br />
to your applications. With XDS<br />
NIR from FOSS, you can reduce operating<br />
overhead, improve the consistency and<br />
quality of your products and optimize your<br />
manufacturing operations – XDS is the<br />
best solution for your cost effective and efficient<br />
analytical requirements.<br />
Facilities<br />
FOSS has manufacturing facilities in Sweden,<br />
Denmark, and the U.S.
www.spectroscopyonline.com<br />
Glass Expansion<br />
DECEMBER 2009 SPECTROSCOPY CORPORATE CAPABILITIES 29<br />
Glass Expansion<br />
4 Barlows Landing Road<br />
Unit #2A<br />
Pocasset, MA 02559<br />
TELEPHONE<br />
(508) 563-1800<br />
(800) 208-0097<br />
FAX<br />
(508) 563-1802<br />
E-MAIL<br />
enquiries@geicp.com<br />
WEB SITE<br />
www.geicp.com<br />
YEAR FOUNDED<br />
1985<br />
Company Description<br />
Glass Expansion has been manufacturing sample introduction<br />
components for ICP emission and mass spectrometers since<br />
the early 1980s. Today we support both new and old instruments<br />
for 16 different manufacturers, representing sample<br />
introduction systems for over 50 different ICP-AES and ICP-MS<br />
models. Glass Expansion has developed unique and proprietary<br />
manufacturing methods, which have resulted in the<br />
production of components of high mechanical strength and<br />
micron-level dimensional accuracy to satisfy the narrowest of<br />
analytical specifications, each and every time. Our products<br />
are recognized worldwide for their excellent precision,<br />
cost-effectiveness, and reproducibility of results.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
ICP-AES<br />
ICP-MS<br />
Markets Served<br />
Glass Expansion’s products are used widely in private and<br />
government analytical laboratories within agricultural, environmental,<br />
food, forensic, geological, metallurgical, petrochemical,<br />
and pharmaceutical industries. We support leading<br />
ICP models including Thermo Fisher, PerkinElmer, Varian,<br />
Agilent, SPECTRO Ametek, and Horiba J-Y. Whether you need<br />
just a nebulizer, a complete sample introduction system, or<br />
the answer for a tricky sample, we have the innovative, highquality<br />
products and applications expertise to assist.<br />
Major Products/Services<br />
Nebulizers<br />
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SeaSpray — High Dissolved Solids<br />
Nebulizer<br />
MicroMist — Low Uptake Nebulizer for<br />
all ICPs<br />
Conikal — An Industry Standard<br />
Slurry — For Slurries and Suspensions<br />
PolyCon — Routine High-Precision HF<br />
Analyses<br />
OpalMist — Ideal for Geochemistry and<br />
Semiconductor Industry<br />
VeeSpray — Handles High Particle and<br />
TDS Loads Best.<br />
Spray Chambers<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Tracey Cyclonic — An Industry Standard<br />
Twister Cyclonic — Reduces Solvent<br />
Load<br />
Cinnabar Cyclonic — Low-Volume Spray<br />
IsoMist programmable temperature<br />
spray chamber<br />
Torches<br />
⦁<br />
⦁<br />
⦁<br />
Fully Demountable D-Torches<br />
Semi-Demountable Torches<br />
Fixed Quartz Torches<br />
RF Coils<br />
Replacement RF Coils with optional silver<br />
or gold coating.<br />
Accesories<br />
⦁<br />
⦁<br />
⦁<br />
Niagara Plus – Enhanced productivity<br />
accessory<br />
Capricorn – Argon humidifier<br />
TruFlo – sample uptake monitor<br />
Facilities<br />
Today, Glass Expansion has two global<br />
offices located in Australia and the United<br />
States. Between our two offices and<br />
network of distributors, we service every<br />
region of the globe, 24 hours a day. This<br />
ensures you receive a rapid response and<br />
timely order deliveries each and every<br />
time.
30 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
Harrick Scientific Products, Inc.<br />
Harrick Scientific<br />
Products, Inc.<br />
141 Tompkins Ave,<br />
2nd Floor<br />
Pleasantville, NY 10570<br />
TELEPHONE<br />
(800) 248-3847<br />
FAX<br />
(914) 747-7209<br />
E-MAIL<br />
info@harricksci.com<br />
WEB SITE<br />
www.harricksci.com<br />
NUMBER OF EMPLOYEES<br />
21<br />
YEAR FOUNDED<br />
1969<br />
Company Description<br />
Harrick Scientific Products specializes in designing and<br />
manufacturing instruments for optical spectroscopy. Since<br />
being established in 1969, Harrick Scientific has advanced<br />
the frontiers of optical spectroscopy through its innovations<br />
in all spectroscopic techniques. The founder of the company,<br />
Dr. N.J. Harrick, pioneered ATR (attenuated total reflection)<br />
spectroscopy and became the principal developer of this<br />
technique. Harrick Scientific offers a complete selection of<br />
sampling accessories, including both standard and custom<br />
designs, as well as an extensive line of optical elements.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
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Transmission<br />
Specular reflection<br />
Diffuse reflection<br />
ATR<br />
Fiberoptics<br />
Markets Served<br />
Harrick Scientific serves analytical markets worldwide.<br />
Harrick’s customers typically are from research or quality<br />
control laboratories of industrial, governmental, research, and<br />
academic institutions throughout the world. Industries served<br />
include chemical, electronic, pharmaceutical, forensics, and<br />
biomedical.<br />
Major Products/Services<br />
Harrick Scientific offers the most complete<br />
line of spectroscopy sampling products,<br />
including:<br />
⦁<br />
⦁<br />
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Video Meridian — a diamond micro ATR<br />
accessory with built-in camera<br />
MVP Pro Star — an affordable<br />
monolithic diamond ATR accessory<br />
Praying Mantis — a diffuse reflectance<br />
accessory available with environmental<br />
chambers/reaction cells<br />
Seagull — a variable angle specular<br />
reflection and ATR accessory<br />
VariGATR — a variable angle grazing<br />
angle ATR accessory for monolayers on<br />
Gold and Silicon substrates<br />
FiberMate 2 — an interface between<br />
spectrometers and fiberoptic applications<br />
MultiLoop, Omni-Diff, and<br />
Omni-Spec — fiberoptic probes for ATR,<br />
diffuse reflection, and specular<br />
reflection<br />
A variety of liquid and gas transmission<br />
cells<br />
Custom design development<br />
Facilities<br />
Harrick Scientific Products is located 30<br />
miles north of New York City in Pleasantville,<br />
New York. Our products are also<br />
available through FT-IR and UV/Vis spectrometer<br />
manufacturers, as well as distributors<br />
in the United States and throughout<br />
the world.
www.spectroscopyonline.com<br />
DECEMBER 2009 SPECTROSCOPY CORPORATE CAPABILITIES 31<br />
Hitachi High Technologies America<br />
Markets Served<br />
Hitachi offers a wide variety of high-quality<br />
UV-Vis/NIR and Fluorescence spectroscopy<br />
systems designed for various applications<br />
from simple, routine analyses to leading<br />
edge research-grade experiments.<br />
Hitachi High<br />
Technologies America<br />
5100 Franklin Drive<br />
Pleasanton, CA 94588<br />
TELEPHONE<br />
(800) 548-9001<br />
FAX<br />
(925) 218-2900<br />
E-MAIL<br />
Sales-LS@hitachi-hta.com<br />
WEB SITE<br />
http://www.hitachi-hta.com/<br />
LShome<br />
NUMBER OF EMPLOYEES<br />
450<br />
YEAR FOUNDED<br />
1979<br />
Company Description<br />
Hitachi High Technologies America, Inc. (HTA), located in<br />
Schaumburg, Illinois, is the North American Division headquarters<br />
for Hitachi High Technologies Corporation (Tokyo,<br />
Japan). Hitachi has a distinguished 40 year history of providing<br />
a very broad range of high-quality analytical equipment<br />
and services in North America. HTA comprises many divisions,<br />
including the Life Sciences Division located in Pleasanton,<br />
California. HTA’s Life Sciences Division markets, sells, and services<br />
LC–MS, UV-Vis/Fluorescence spectroscopy, liquid chromatography,<br />
and amino acid analysis instrumentation. HTA’s<br />
activities include application development, customer support<br />
and service, product development, application, training, sales,<br />
and marketing.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
UV <strong>Spectroscopy</strong><br />
Fluorescence <strong>Spectroscopy</strong><br />
Liquid chromatography – mass spectrometry<br />
Ultra high-speed liquid chromatography<br />
High performance liquid chromatography<br />
Dedicated amino acid analysis<br />
Diffraction gratings<br />
Major Products/Services<br />
The state-of-the-art spectrofluorometer,<br />
the Model F-7000, has set a new standard<br />
in performance with ultra-high sensitivity<br />
(S/N: 800) and high-speed scanning<br />
(60,000 nm/min).<br />
The Model U-3900 double-beam singlemonochromator<br />
system and the Model<br />
U-3900H double-beam double-monochromator<br />
system are high-performance,<br />
comprehensive, research-grade solutions<br />
for a variety of applications.<br />
Hitachi’s new LachromUltra is a flexible<br />
new Ultra High-Speed Liquid Chromatograph,<br />
delivering ultra-fast analysis, higher<br />
resolution, increased sensitivity and the<br />
flexibility to run both conventional and ultra-high<br />
resolution LC analyses on a single<br />
system. LaChromUltra is the practical next<br />
generation LC solution that meets the<br />
needs and budget of analytical<br />
laboratories.<br />
The Hitachi LaChrom Elite HPLC System<br />
and the L-8900 Amino Acid Analyzer continue<br />
to set the standard for performance<br />
and reliability, demonstrating unparalleled<br />
analytical sensitivity.<br />
Facilities<br />
Pleasanton, California, is the headquarters<br />
for the Life Sciences Division and includes<br />
R&D, sales, marketing, service, and customer<br />
support. HTA also offers extensive<br />
field sales, service, and support capabilities<br />
throughout the US, Canada, and Mexico.
32 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
HORIBA Scientific<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Forensic Science<br />
Life Sciences<br />
Medical<br />
Metals, Plastics, Polymers, etc.<br />
Optoelectronics<br />
Petroleum<br />
Pharmaceuticals<br />
Semiconductors<br />
HORIBA Scientific<br />
3880 Park Avenue<br />
Edison, NJ 08820<br />
TELEPHONE<br />
(732) 494-8660<br />
FAX<br />
(732) 494-5125<br />
E-MAIL<br />
info.sci@horiba.com<br />
WEB SITE<br />
www.horiba.com/scientific<br />
NUMBER OF EMPLOYEES<br />
USA: 600<br />
Elsewhere: 5000<br />
YEAR FOUNDED<br />
1819<br />
Company Description<br />
HORIBA Scientific is a leading manufacturer of innovative<br />
spectroscopic systems and components, and we are committed<br />
to serving our customers with superior products and<br />
technical support in optical spectroscopy.<br />
HORIBA Scientific is part of the HORIBA Group, which employs<br />
5000 people worldwide, with annual sales in excess of<br />
$1.5 billion. HORIBA Jobin Yvon, Sofie, Dilor, Spex®, and IBH<br />
are some of our well-known and respected brand names.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Molecular Fluorescence <strong>Spectroscopy</strong><br />
Optical <strong>Spectroscopy</strong><br />
Raman <strong>Spectroscopy</strong> and Microscopy<br />
Ellipsometry and Thin-Film Analysis<br />
Atomic Emission <strong>Spectroscopy</strong><br />
Fluorescence<br />
Forensic Science<br />
Markets Served<br />
⦁<br />
⦁<br />
⦁<br />
Academia<br />
Coatings<br />
Environmental<br />
Major Products/Services<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
<strong>Spectroscopy</strong> and Analysis<br />
Elemental Analyzers<br />
Ellipsometers<br />
End-Point Detectors<br />
Fluorescence<br />
Gratings<br />
ICP & GD Spectrometers<br />
Lifetime Fluorescence<br />
Microscopy<br />
OEM Components<br />
Particle-Size Analyzers<br />
Process Control<br />
Raman & FT-IR<br />
Spectrographs<br />
Spectrometers and CCDs<br />
VUV equipment<br />
X-Ray Fluorescence<br />
Surface Plasmon Resonance Imaging<br />
(SPRi)<br />
Particle-Size Systems<br />
Facilities<br />
HORIBA Scientific manufactures quality<br />
instruments in Edison, New Jersey, as well<br />
as France and Japan.<br />
Sales, service, and applications facilities<br />
are located around the world. We are an<br />
ISO 9001:2008-certified company.
www.spectroscopyonline.com<br />
OptiGrate Corp.<br />
DECEMBER 2009 SPECTROSCOPY CORPORATE CAPABILITIES 33<br />
OptiGrate Corp.<br />
3267 Progress Drive<br />
Orlando, FL 32826<br />
TELEPHONE<br />
(407) 381-4115<br />
FAX<br />
(407) 384-5995<br />
E-MAIL<br />
info@optigrate.com<br />
WEB SITE<br />
www.OptiGrate.com<br />
NUMBER OF EMPLOYEES<br />
20<br />
YEAR FOUNDED<br />
1999<br />
Company Description<br />
OptiGrate Corp. designs and manufactures ultra narrow band<br />
optical filters based on volume Bragg grating (VBG) technologies<br />
in proprietary photosensitive glass. Filters with bandwidth<br />
as low as 30 pm are formed by holographic techniques in the<br />
bulk of glass material and demonstrate superior optical quality,<br />
outstanding durability, and high optical damage threshold.<br />
OptiGrate is a pioneer and world leader in VBG technologies<br />
and, for over 10 years, OptiGrate has delivered custom build<br />
and volume orders of holographic optical elements (HOE) to<br />
government contractors, industrial manufacturers, and key<br />
academic players. OptiGrate has an exclusive license to a full<br />
portfolio of unique VBG-based products deployed in various<br />
industries.<br />
Markets Served<br />
OptiGrate supplied ultra narrow band filters to hundreds of<br />
customers on 5 continents. The filters are used in a wide<br />
range of applications in optoelectronic, analytical, defense,<br />
and semiconductor industries. Major markets include:<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Raman spectroscopy and microscopy<br />
Semiconductor, solid state, and fiber lasers<br />
Hyperspectral and Raman imaging<br />
Photonics applications in defense sector<br />
Ultrafast laser systems<br />
Optical recording and storage<br />
Medical diagnostics and treatment<br />
Major Products/Services<br />
⦁<br />
Notch Filters — laser line rejection filters with bandwidth<br />
less than 10 cm -1<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Bandpass Filters — laser side-mode<br />
suppression filters with bandwidth less<br />
than 10 cm -1<br />
Laser resonator mode selection filter for<br />
spectral narrowing and thermal stabilization<br />
of lasers<br />
Deflectors — transmitting volume Bragg<br />
grating for angular filtering and deflection<br />
of laser light<br />
Chirped volume Bragg grating for ultrashort<br />
laser pulse stretching and<br />
compression<br />
Spectral Beam Combiner — angular<br />
and spectral filters for high-power laser<br />
spectral beam combining<br />
Facilities<br />
OptiGrate designs, develops, and makes<br />
all products in Orlando, Florida. The volume<br />
Bragg grating filters are manufactured<br />
in a unique, vertically integrated facility<br />
that includes photosensitive glass production<br />
facility, holographic facility, and laser<br />
development facility. OptiGrate’s internal<br />
capability to develop, fine-tune, and mass<br />
produce photosensitive glass, the core of<br />
VBG technology, provides better process<br />
control and stability and also enables<br />
fabrication of filters with record characteristics.
34 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
International Centre for Diffraction Data<br />
International Centre for<br />
Diffratcion Data<br />
12 Campus Boulevard<br />
Newton Square, PA 19073<br />
TELEPHONE<br />
(610) 325-9814<br />
(866) 378- 9331<br />
FAX<br />
(610) 325-9823<br />
E-MAIL<br />
info@icdd.com<br />
WEB SITE<br />
www.icdd.com<br />
YEAR FOUNDED<br />
1941<br />
Company Description<br />
ICDD, a not-for-profit corporation, is dedicated to the collecting,<br />
editing, and publishing of the Powder Diffraction File<br />
(PDF ® ). Our mission is to be the world center for quality diffraction<br />
data meeting the needs of the technical community.<br />
We promote the application of materials characterization<br />
methods by sponsoring the Denver X-ray Conference; its proceedings,<br />
Advances in X-ray Analysis, and the journal, Powder<br />
Diffraction. ICDD and its members conduct workshops and<br />
clinics on materials characterization at our headquarters in<br />
Newton Square, Pennsylvania and at X-ray analysis workshops<br />
around the world.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
X-ray Diffraction<br />
Electron Diffraction<br />
Electron Backscatter Diffraction<br />
Markets Served<br />
The Powder Diffraction File is designed for materials identification<br />
and characterization. ICDD databases are used worldwide<br />
by scientists in academia, government, and industry who<br />
are actively engaged in the field of X-ray powder diffraction<br />
and related disciplines.<br />
Major Products/Services<br />
Release 2009 of the Powder Diffraction File contains over<br />
662,000 unique material data sets. Each data set contains<br />
diffraction, crystallographic, and bibliographic data, as well as<br />
experimental, instrument, and sampling conditions and select<br />
physical properties in common standardized<br />
format. The PDF’s large size and comprehensive<br />
material coverage is achieved<br />
through ICDD’s historial sources of powder<br />
diffraction data, ICDD’s Grant-in-Aid<br />
Program, contributions, and bibliographic<br />
searches, as well as collaborations with<br />
international crystallographic database<br />
organizations. The database is designed<br />
and produced in several different formats<br />
(PDF-4+, PDF-2, PDF-4/Minerals, and<br />
PDF-4/Organics) in order to serve different<br />
groups of users.<br />
PDF-4+ 2009 is our advanced database<br />
with comprehensive material coverage<br />
for inorganic materials. The database is a<br />
powerful tool for phase identification using<br />
physical, chemical, and crystallographic<br />
data. It contains numerous features, such<br />
as 291,440 data sets, digitized patterns,<br />
molecular graphics, and atomic parameters.<br />
Many new features have been incorporated<br />
into the PDF-4+ to enhance the<br />
ability to do quantitative analysis by any<br />
of three methods: Rietveld Analysis, Reference<br />
Intensity Ratio (RIR) method, or Total<br />
Pattern Analysis. PDF-4+ also features<br />
electron diffraction simulations based on<br />
atomic structure and electron diffraction<br />
scattering factors on >260,000 data sets.<br />
The simulations include electron diffraction<br />
powder pattern, spot pattern, and<br />
electron diffration backscatter pattern.
36 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
IDEX Health & Science<br />
Major Products/Services<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Precision fluidic research, development,<br />
and engineering<br />
Integrated fluidic subassemblies<br />
Liquid handling systems<br />
Low volume, high precision pumps,<br />
including positive displacement, peristaltic,<br />
piston and gear technologies<br />
Shear valves<br />
Debubbler and degassing systems<br />
Manifolds and precision machined<br />
plastic components<br />
Custom tubing and assemblies<br />
Connections and flow control products<br />
IDEX Health & Science<br />
619 Oak Street<br />
Oak Harbor, WA 98277<br />
TELEPHONE<br />
(866) 339-4653<br />
FAX<br />
(360) 682-4151<br />
E-MAIL<br />
HealthandScience@idexcorp.com<br />
WEB SITE<br />
www.idex-hs.com<br />
Company Description<br />
IDEX Health & Science designs, develops, and manufactures<br />
liquid subassemblies and precision components for a wide<br />
range of applications requiring precise control and measurement.<br />
We specialize in component integration that results in<br />
innovative and optimized OEM fluidic systems. IDEX Health<br />
& Science is the synthesis of leading component and technology<br />
suppliers to the analytical instrument, diagnostics,<br />
biotechnology, industrial, and semiconductor markets. Our<br />
brands include Eastern Plastics, Innovadyne, Ismatec, Isolation<br />
Technologies, Rheodyne, Sapphire Engineering, Systec, and<br />
Upchurch Scientific.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
UV/Visible<br />
Infrared (including FT-IR & NIRS)<br />
Fluorescence<br />
Mass <strong>Spectroscopy</strong><br />
Laser (including Raman)<br />
Markets Served<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Analytical Instrumentation<br />
Biotech<br />
In Vitro Diagnostics<br />
Medical Device<br />
Medical Equipment<br />
Industrial<br />
Semiconductor<br />
Facilities<br />
Manufacturing facilities in North America<br />
and Asia. Class 1,000, 10,000, and<br />
100,000 Clean Rooms.<br />
.
38 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
Inorganic Ventures<br />
Development, Textile, Transportation, and<br />
Wastewater Treatment, to name a few.<br />
Inorganic Ventures<br />
300 Technology Drive<br />
Christiansburg, VA 24073<br />
TELEPHONE<br />
(800) 669-6799 (US &<br />
Canada)<br />
(540) 585-3030<br />
FAX<br />
(540) 585-3012<br />
E-MAIL<br />
info@inorganicventures.com<br />
WEB SITE<br />
inorganicventures.com<br />
YEAR FOUNDED<br />
1985<br />
Company Description<br />
Inorganic Ventures is the only standard manufacturer to specialize<br />
in the formulation of custom inorganic solutions. We<br />
excel in providing service and support tailored to your specific<br />
needs. In short, we flex to your specs.<br />
Our specialization in custom blending means that we can<br />
create precise standards faster than other manufacturers. Over<br />
99% of our custom blends ship within five business days or<br />
less. In addition to customization, we offer a wide selection<br />
of stock inorganic standards. Contact us to receive our new<br />
catalog.<br />
For nearly a decade, Inorganic Ventures has been registered<br />
to ISO Guide 34, ISO/IEC 17025 and ISO 9001:2000 by<br />
A2LA and QMI.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
ICP-OES/AES<br />
ICP-MS<br />
IC<br />
AA<br />
GFAA<br />
DCP<br />
Markets Served<br />
We provide custom and conventional certified reference materials<br />
for dozens of markets, including Aeronautical, Agricultural,<br />
Automotive, Chemical, Colleges and Universities, Construction,<br />
Cosmetic, Energy, Environmental, Food Industries,<br />
Government Agencies, Medical, Metallurgical, Military, Mining,<br />
Nuclear, Petroleum, Pharmaceutical, Plastics, Research and<br />
Major Products/Services<br />
Our specialists customize and manufacture<br />
inorganic standards for laboratories<br />
worldwide. We create aqueous calibration<br />
standards, quality control standards, and<br />
chemical reagents, plus a wide selection<br />
of ion chromatography standards and<br />
CRMs for the latest EPA methods. Over<br />
99% of our custom solutions ship within<br />
five business days. Stock orders ship<br />
same-day prior to 4:00 pm EST. Experts<br />
are available during regular business hours<br />
to provide in-depth technical support. Furthermore,<br />
the Inorganic Ventures’ website,<br />
inorganicventures.com, has been cited by<br />
chemists as one of the best sources for<br />
analytical support on the Web.<br />
Facilities<br />
In 2009 we completed our corporate relocation<br />
to our new state-of-the-art manufacturing<br />
laboratory in Christiansburg,<br />
Virginia. This eco-friendly laboratory offers<br />
contamination-free manufacturing during<br />
every stage of production. Most foreign<br />
orders ship from our European distribution<br />
center in Madrid, Spain.
40 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
KLASTECH Karpushko Laser<br />
Technologies<br />
Major Products/Services<br />
KLASTECH CW DPSS portfolio includes<br />
lasers at 1064 nm (SENZA), 694.3 nm<br />
(CRESCENDO) , 532 nm (SYMPHONY &<br />
SCHERZO), 488 nm (BLUE NOTE), 266<br />
nm (VERVE), and 442 nm (Concerto) with<br />
other wavelengths in development. All<br />
KLASTECH lasers are inherently single frequency<br />
in performance.<br />
Facilities<br />
KLASTECH manufactures all its lasers in<br />
its state of the art facility in Dortmund,<br />
Germany that includes the latest ESD protected<br />
laboratories and production clean<br />
rooms.<br />
KLASTECH Karpushko<br />
Laser Technologies<br />
Konrad-Adenauer-Allee 11<br />
44263 Dortmund, Germany<br />
TELEPHONE<br />
49 (0) 231 477 30 648<br />
FAX<br />
49 (0) 231 477 30 620<br />
E-MAIL<br />
n.steinkretzer@klastech.de<br />
WEB SITE<br />
www.klastech.com<br />
NUMBER OF EMPLOYEES<br />
USA: 1<br />
Elsewhere: 24<br />
Company Description<br />
KLASTECH specializes in the manufacturing of an entirely<br />
new and completely revolutionary range of CW DPSS lasers.<br />
Powered by our patented intra-cavity frequency doubling<br />
technology our range includes the world’s first and only true<br />
CW ruby laser, a revolutionary new CW 266 nm laser and due<br />
for release in December, a direct DPSS alternative to the He-<br />
Cd gas laser. Our 1064 nm, 532 nm, and 488 nm lasers complete<br />
our comprehensive portfolio. Our technology inherently<br />
delivers lasers that produce Pitch Perfect, ultra quiet, single<br />
frequency laser light with diffraction limited beam profiles,<br />
enabling analytical instrument designers and researchers alike<br />
to surpass their highest expectations.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
Raman<br />
Bio-fluorescence<br />
Markets Served<br />
KLASTECH DPSS lasers are used widely by spectroscopists in<br />
research and by instrument designers due to their inherent<br />
single frequency nature and their long term power and beam<br />
pointing stability.<br />
YEAR FOUNDED<br />
2005
42 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
Moxtek, Inc.<br />
Major Products/Services<br />
ProFlux Wiregrid polarizers<br />
High transmission and contrast inorganic<br />
polarizers for UV, Visible, and IR<br />
applications.<br />
Magnum miniature x-ray sources<br />
The leading x-ray source technology for<br />
handheld and bench top x-ray analysis<br />
applications<br />
XPIN Detectors<br />
The latest generation of affordable<br />
Si-PIN detectors for x-ray fluorescence<br />
spectrometry<br />
AP3 and ProLINE windows<br />
Ultrathin polymer windows for energy and<br />
wavelength dispersive spectroscopy<br />
DuraBeryllium windows<br />
Most rugged and reliable beryllium windows<br />
available for x-ray applications<br />
MX series JFET<br />
The lowest noise JFET available for x-ray<br />
detection systems.<br />
Facilities<br />
Headquarters in Orem, Utah.<br />
Moxtek, Inc.<br />
452 W 1260 N<br />
Orem, UT 84057<br />
TELEPHONE<br />
(801) 225-0930<br />
Toll-free: (800) 758-3110<br />
FAX<br />
(801) 221-1121<br />
E-MAIL<br />
Moxtek@moxtek.com<br />
WEB SITE<br />
www.moxtek.com<br />
NUMBER OF EMPLOYEES<br />
105<br />
YEAR FOUNDED<br />
1986<br />
Company Description<br />
We are a leading supplier of x-ray and optical components for<br />
analytical instrumentation and display electronics. Products<br />
include the new XPIN high-performance Si-PIN x-ray<br />
detectors; Magnum miniature low-power x-ray sources;<br />
AP3 and DuraBeryllium x-ray windows for EDS; ProLINE<br />
windows for WDS; and ProFlux wire-grid polarizers and beam<br />
splitters for UV, Visible, and IR spectroscopy. MOXTEK is well<br />
known for advanced technology, innovative solutions, and<br />
excellent customer service.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Energy dispersive x-ray spectroscopy<br />
Wavelength dispersive x-ray spectroscopy<br />
X-ray diffraction<br />
Microanalysis<br />
UV, Visible, IR spectrometry<br />
Markets Served<br />
Moxtek, Inc. serves the analytical instrumentation and<br />
projection display markets.<br />
Customer Support<br />
Technical support is provided by our team<br />
of skilled electronics, mechanical, and<br />
process engineers.
44 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
Newport Corporation<br />
of product innovation and expertise.<br />
Together they deliver a synergy of knowledge<br />
across a broad spectrum of products,<br />
along with the ability to deliver unsurpassed<br />
solutions and integration.<br />
Newport Corporation<br />
1791 Deere Avenue<br />
Irvine, CA 92606<br />
TELEPHONE<br />
(800) 222-6440<br />
FAX<br />
(949) 253-1800<br />
E-MAIL<br />
sales@newport.com<br />
WEB SITE<br />
www.newport.com<br />
YEAR FOUNDED<br />
1969<br />
Company Description<br />
Newport is a world leading supplier of innovative photonic<br />
solutions to Make, Manage, and Measure Light SM . The company’s<br />
broad product portfolio includes an extensive selection<br />
of lasers, high-quality light sources, optomechanics, optics,<br />
filters, gratings, crystals, optical tables, and motion systems.<br />
As the industry’s first and only integrated supplier of laser and<br />
photonic components, Newport does more than just deliver<br />
components. They also leverage a unique ability to integrate<br />
multiple core technologies, a full range of engineering design<br />
services, metrology certification, manufacturing control programs,<br />
and world-class service and support, and offer a wide<br />
variety of subsystems, subassembly, and turnkey systems to<br />
our customers.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
UV–Vis<br />
Infrared<br />
Fluorescence<br />
Raman<br />
Ultrafast<br />
Markets Served<br />
Newport provides advanced-technology products to the<br />
research, aerospace and defense, life and health sciences,<br />
photovoltaics, semiconductor, and microelectronics markets.<br />
For over 40 years Newport has continued to grow and<br />
today is built upon world-class brands such as; Corion ® ,<br />
New Focus, Oriel ® Instruments, Richardson Gratings and<br />
Spectra-Physics ® . Alone, each of these brands has a rich history<br />
Major Products/Services<br />
As a combined force, Newport, and its<br />
family of brands, is a premier global<br />
resource for solutions to Make, Manage,<br />
and Measure light. Newport’s breadth<br />
of product offerings combined with our<br />
experience and expertise allow us to<br />
meet our customers at any place on the<br />
technology roadmap. Our lasers, photonic<br />
instrumentation, optical tables, motion<br />
control solutions, optics, filters, gratings,<br />
opto-mechanics, and spectroscopy instruments<br />
are used in research and scientific<br />
laboratories, microelectronics and semiconductor<br />
manufacturing, life & health sciences,<br />
aerospace & defense, and industrial<br />
manufacturing. Expanding upon its 40+<br />
year history of innovation in photonics,<br />
Newport is a single-source provider for all<br />
your laser and photonics needs.<br />
Facilities<br />
Newport Corporation has offices in over<br />
10 countries worldwide, including over<br />
600,000 square feet of office and manufacturing<br />
space. The company is headquartered<br />
in Irvine, California. This facility<br />
houses sales, marketing, engineering,<br />
and manufacturing, including facilities for<br />
optics, opto-mechanical assemblies, and<br />
instrumentation. The Spectra-Physics and<br />
New Focus laser manufacturing facilities<br />
are headquartered in Santa Clara, California.<br />
Other offices include Oriel spectroscopy<br />
products in Stratford, Connecticut;<br />
Richardson gratings in Rochester, New<br />
York; Corion filter products and replicated<br />
mirrors in Franklin, Massachusetts; manufacturing<br />
facilities in Darmstadt, Germany,<br />
and Evry, France; and numerous local<br />
sales offices throughout Europe and Asia.
www.spectroscopyonline.com<br />
DECEMBER 2009 SPECTROSCOPY CORPORATE CAPABILITIES 45<br />
Nippon Instruments North America<br />
⦁<br />
⦁<br />
budget requirements. These analyzers<br />
provide simple, highly effective results<br />
for such methods as EPA 245.1.<br />
Model RA-3420 Mercury Analyzer: A<br />
unique analyzer that performs the typical<br />
EPA Method 245.1 analysis in a fully<br />
automatic sequence, including sample<br />
preparation.<br />
Model PE-1000 Mercury Analyzer: A<br />
specifically designed mercury analyzer<br />
for direct, automated analysis of mercury<br />
in liquid and gaseous hydrocarbons.<br />
Nippon Instruments<br />
North America<br />
1511 Texas Ave S #270<br />
College Station, TX 77840<br />
TELEPHONE<br />
(979) 774-3800<br />
FAX<br />
(979) 774-3807<br />
E-MAIL<br />
sales@hg-nic.us<br />
WEB SITE<br />
www.hg-nic.us<br />
NUMBER OF EMPLOYEES<br />
19<br />
YEAR FOUNDED<br />
2003<br />
Company Description<br />
Nippon Instruments North America is the regional office for<br />
Nippon Instruments Corporation-Japan. Nippon Instruments<br />
has over 30 years of experience in the design and manufacture<br />
of high-quality mercury analyzers. With an absolute focus<br />
on mercury analyzers, Nippon Instruments offers mercury<br />
analyzers for just about every application. From systems for<br />
most EPA Methods to direct mercury analyzers to online<br />
monitoring systems to specially designed systems for the petrochem<br />
industry, Nippon Instruments has a mercury analyzer<br />
for your laboratory.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
Atomic Absorption <strong>Spectroscopy</strong><br />
Atomic Fluorescence <strong>Spectroscopy</strong><br />
Markets Served<br />
Nippon Instruments provides mercury analyzers for EPA compliance<br />
monitoring in the environmental, government,and<br />
industrial markets. We provide highly versatile systems for the<br />
research and education markets, as well as mercury analyzers<br />
that are specifically designed for the unique tasks of the<br />
industrial and petrochem markets.<br />
Major Products/Services<br />
⦁<br />
⦁<br />
Model MA-2000 Mercury Analyzer: A direct mercury<br />
analyzer that allows for mercury analysis of just about any<br />
matrix without the need for sample preparation.<br />
Model RA-3000 Series Mercury Analyzers: Mercury analyzers<br />
with several configurations available to fit various<br />
Facilities<br />
Nippon Instruments North America is in<br />
the final stages of building a new office in<br />
College Station, Texas, in order to continue<br />
to expand our capabilities. Nippon Instruments<br />
Corporation currently maintains offices<br />
in Osaka and Tokyo, Japan, as well as<br />
an additional office in Singapore.
46 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
Ocean Optics, Inc.<br />
the research community has embraced<br />
our systems and components for everything<br />
from cancer detection to solar cell<br />
analysis. In fact, you can find Ocean Optics<br />
products in virtually any application from<br />
food safety to forensics and from semiconductors<br />
to marine biology.<br />
Ocean Optics<br />
830 Douglas Ave.<br />
Dunedin, FL 34698<br />
TELEPHONE<br />
727-733-2447<br />
FAX<br />
727-733-3962<br />
E-MAIL<br />
Info@oceanoptics.com<br />
WEB SITE<br />
www.OceanOptics.com<br />
NUMBER OF EMPLOYEES<br />
250<br />
YEAR FOUNDED<br />
1989<br />
Company Description<br />
Ocean Optics invented the world’s first miniature spectrometer<br />
and has delivered over 130,000 of them since its inception<br />
in 1989. The company provides solutions for diverse applications<br />
of optical sensing in medical and biological research,<br />
environmental regulation, science education, production, and<br />
process control. Ocean Optics also provides a comprehensive<br />
range of complementary technologies including chemical sensors,<br />
metrology instrumentation, optical fibers, probes, filters,<br />
coatings, and many more spectroscopic peripherals and accessories.<br />
Our spectrometers and sensors are also ideal for<br />
OEM applications — with modular options that meet virtually<br />
any application requirement.<br />
Chief Spectroscopic Techniques Supported<br />
Absorbance, transmission, reflectance, irradiance, fluorescence,<br />
Raman, UV/VIS/NIR, spectroradiometry, color spectroscopy,<br />
laser-induced breakdown spectroscopy (LIBS), fiber<br />
optic chemical sensing, flow injection analysis, elemental<br />
analysis, endpoint detection, headspace monitoring, laser<br />
characterization, nondestructive testing, multi-spectral<br />
imaging.<br />
Markets Served<br />
Ocean Optics technologies can be found in a diverse range of<br />
industries and disciplines. Our products are used by innovators,<br />
researchers, scientists, OEMs, medical and healthcare<br />
professionals, and in manufacturing facilities in every country<br />
on the planet. Military and security concerns have incorporated<br />
Ocean Optics technologies into their equipment while<br />
Major Products/Services<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Spectrometers: UV/VIS/NIR, highresolution,<br />
time-gated fluorescence,<br />
spectrofluorometers, absorbance, laserinduced<br />
breakdown, LED measurement,<br />
reflectance, Raman, remote sensing,<br />
field measurement.<br />
Optical Sensors: Oxygen sensors, pH<br />
sensors, transducing materials.<br />
Software: Spectrometer operating,<br />
device drivers, irradiance, reflective and<br />
emissive color, compound identification.<br />
Sampling Accessories: Collimating<br />
lenses, cuvettes and holders, standards,<br />
filters and holders, flow cells, cosine<br />
correctors, integrating spheres.<br />
Light Sources: Deuterium, tungsten<br />
halogen, LED, excitation sources, lasers.<br />
Optical Fibers and Probes: Premium<br />
grade assemblies, bare fiber, custom<br />
options, reflection and transmission<br />
probes, vacuum feedthroughs,<br />
complete fiber kits.<br />
Facilities<br />
Ocean Optics is headquartered in Dunedin,<br />
Florida and has full-service locations<br />
in Europe as well as China. Ocean Optics<br />
is part of Halma p.l.c., a safety and environmental<br />
technology group in the United<br />
Kingdom.
48 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
PANalytical<br />
steel, nanomaterials, plastics, polymers<br />
and petrochemicals, industrial minerals,<br />
glass, catalysts, semiconductors thin films<br />
and advanced materials, pharmaceutical<br />
solids, recycled materials and environmental<br />
samples.<br />
PANalytical<br />
117 Flanders Road<br />
Westborough, MA 01581<br />
TELEPHONE<br />
(508) 647-1100<br />
FAX<br />
(508) 647-1115<br />
E-MAIL<br />
amec.info@panalytical.com<br />
WEB SITE<br />
www.panalytical.com<br />
NUMBER OF EMPLOYEES<br />
USA: 100<br />
Worldwide: 800<br />
YEAR FOUNDED<br />
1954<br />
Company Description<br />
PANalytical is the world’s leading supplier of analytical instrumentation<br />
and software for X-ray diffraction (XRD) and X-ray<br />
fluorescence spectrometry (XRF), with more than half a century<br />
of experience. The materials characterization equipment<br />
is used for scientific research and development, for industrial<br />
process control applications, and for semiconductor<br />
metrology.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
X-ray Diffraction: X-ray diffraction is a versatile, nondestructive<br />
technique that reveals detailed information about the<br />
chemical composition and crystallographic structure of<br />
natural and engineered materials.<br />
X-ray Fluorescence Spectrometry: X-ray fluorescence spectrometry<br />
is a nondestructive analytical technique used to<br />
identify and determine the concentrations of elements<br />
present in solid, powdered, and liquid samples. The spectrometer<br />
measures the fluorescent emission produced by a<br />
sample when irradiated with X-rays.<br />
Markets Served<br />
The product portfolio includes a broad range of XRD and XRF<br />
systems and software widely used for the analysis and materials<br />
characterization of products such as cement, metals and<br />
Major Products/Services<br />
The X-ray fluorescence product line offers<br />
a range of WDXRF and EDXRF instrumentation,<br />
from the MinPal4 benchtop systems<br />
to the industry leading Axios family<br />
of WDXRF spectrometers. In 2009, PANalytical<br />
has set the new benchmark in standardless<br />
XRF analysis with the introduction<br />
of Omnian software. The Epsilon5 EDXRF<br />
system offers unparalleled performance<br />
in ultra trace element analysis. All XRF<br />
instrumentation is backed by complete<br />
application solutions including standards<br />
for many industries, and the largest global<br />
network of application support and service<br />
of any analytical X-ray vendor. The Diffraction<br />
product line includes the proven<br />
choice for speed, resolution and true<br />
flexibility, X’Pert PRO MPD with the PIXcel<br />
detector; Alpha-1, the highest resolution<br />
powder diffractometer available; X’Pert<br />
PRO MRD and MRD-XL, diffractometers<br />
specializing in advanced material characterization<br />
such as semiconductor wafers;<br />
and CubiX3, our latest generation of successful<br />
industrial diffractometers, now<br />
the fastest diffractometer with the PIXcel<br />
detector on board.<br />
Facilities<br />
PANalytical’s headquarters are in Almelo,<br />
the Netherlands. Fully equipped application<br />
laboratories are established in Japan,<br />
China, the USA, and the Netherlands.<br />
PANalytical’s research activities are based<br />
in Almelo (NL) and on the campus of the<br />
University of Sussex in Brighton (UK). Supply<br />
and competence centers are located in<br />
Almelo and Eindhoven (NL). A sales and<br />
service network in more than 60 countries<br />
ensures unrivaled levels of customer<br />
support.
50 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
Parker Hannifin Corporation<br />
Filtration and Separation Division<br />
Markets Served<br />
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Agriculture<br />
Biotechnology<br />
Chemicals<br />
Chemical and explosives detection<br />
Energy<br />
Environmental<br />
Inorganic chemicals<br />
Instrument development<br />
Life science<br />
Organic chemicals<br />
Paints and coatings<br />
Petrochemicals<br />
Pharmaceuticals<br />
Plastics<br />
Parker Hannifin<br />
Corporation<br />
Filtration and Separation<br />
Division<br />
242 Neck Road<br />
Haverhill, MA 01835<br />
TELEPHONE<br />
(978) 858-0505<br />
FAX<br />
(978) 858-0625<br />
WEB SITE<br />
www.labgasgenerators.com<br />
NUMBER OF EMPLOYEES<br />
6,000<br />
YEAR FOUNDED<br />
1924<br />
Company Description<br />
Safety: Parker Balston gas generators completely eliminate<br />
the safety hazards involved with handling high-pressure gas<br />
cylinders. Enjoy hassle-free automation with no tanks to<br />
change and no downtime.<br />
Reliability: Thousands of laboratories worldwide have Parker<br />
Balston gas generators in routine use. Parker Balston gas<br />
generators are recommended and used by major instrument<br />
manufacturers. We offer the best technology at an affordable<br />
price from the brand you trust.<br />
Quality: Each Parker Balston gas generator is manufactured<br />
under a strict total quality management program. We have a<br />
world-class ISO 9001–certified manufacturing facility in the<br />
United States. All Parker Balston gas generators are backed by<br />
a complete satisfaction guarantee.<br />
Products: Hydrogen gas generators produce 99.99999%<br />
pure hydrogen for gas chromatographs. Zero air generators<br />
produce zero grade air for gas chromatographs. UHP nitrogen<br />
generators produce 99.9999% pure nitrogen for GCs or ICP<br />
spectrometers. FTIR gas generators produce dry, CO 2<br />
-free<br />
purge gas for FTIR spectrometers. Pure air and nitrogen generators<br />
produce dry, ultrapure compressed gas for laboratory<br />
instruments, including LC–MS instruments.<br />
Chief Spectroscopic Techniques Supported<br />
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Optical<br />
Atomic<br />
Infrared<br />
Hyphenated Techniques<br />
Major Products/Services<br />
Gas generators for the following analytical<br />
instruments:<br />
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Gas chromatographs<br />
LC–MS<br />
FTIR spectrometers<br />
ICP emission spectrometers<br />
TOC analyzers<br />
Atomic absorption spectrophotometers<br />
Nuclear magnetic resonance (NMR)<br />
Rheometers/Thermal analyzers<br />
Sample evaporators/Concentrators<br />
Facilities<br />
Parker Hannifin manufactures all gas<br />
generator products in Haverhill, Massachusetts.<br />
All Parker Balston products are manufactured<br />
in accordance with a strict Total<br />
Quality Management Program, ensuring<br />
top performance and long-term reliability.<br />
Distribution points stretch across the<br />
United States and worldwide, including<br />
Canada, the UK, China, India, Germany,<br />
France, Japan, and Singapore.
www.spectroscopyonline.com<br />
PerkinElmer<br />
DECEMBER 2009 SPECTROSCOPY CORPORATE CAPABILITIES 51<br />
PerkinElmer, Inc.<br />
940 Winter Street<br />
Waltham, MA 02451<br />
TELEPHONE<br />
(781) 663-6900<br />
FAX<br />
(203) 944-4904<br />
E-MAIL<br />
info@perkinelmer.com<br />
WEB SITE<br />
www.perkinelmer.com<br />
NUMBER OF EMPLOYEES<br />
Worldwide: 8500<br />
YEAR FOUNDED<br />
1937<br />
Company Description<br />
PerkinElmer, Inc. is a global leader focused on improving the<br />
health and safety of people and their environment. Engaged<br />
in a proactive fight against illness, including contamination<br />
and other threats to our well-being, PerkinElmer conceives<br />
and delivers scientific solutions to meet society’s ever-changing<br />
needs. Our mission ranges from fostering earlier insights<br />
and more effective therapies to facilitating cleaner water and<br />
safer buildings where we work, learn, and play. For people<br />
and the environment, we take action to create a better<br />
tomorrow.<br />
Chief Chromatographic Techniques Supported<br />
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Gas Chromatography (GC)<br />
Gas Chromatography/Mass Spectrometry (GC–MS)<br />
Headspace Sampling (HS)<br />
Thermal Desorption (TD & ATD)<br />
Liquid Chromatography (HPLC & UHPLC)<br />
Chromatography Data Systems (CDS)<br />
Markets Served<br />
PerkinElmer is a leading provider of precision instrumentation,<br />
reagents and chemistries, software, and services for a<br />
wide range of scientific and industrial laboratory applications,<br />
including environmental monitoring, food and beverage quality/safety,<br />
and chemical analysis, as well as genetic screening,<br />
drug discovery, and development.<br />
Major Products/Services<br />
PerkinElmer, Inc. offers a wide breadth<br />
of instrumentation and solutions to meet<br />
your analytical measurement needs:<br />
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Gas Chromatography: Clarus® 600,<br />
500, and 400 GCs<br />
Gas Chromatography/Mass Spectrometry:<br />
Clarus® 600 and 560 GC–MS<br />
GC Sample Handling: TurboMatrix®<br />
Headspace and Thermal Desorption<br />
HPLC and UHPLC: Flexar, FX-15, FX-10<br />
Data handling & LIMS: LABWORKS<br />
LIMS, Chromera® CDS, TotalChrom®<br />
CDS<br />
Atomic <strong>Spectroscopy</strong>: AA, ICP-OES,<br />
ICP-MS<br />
Molecular <strong>Spectroscopy</strong>: FTIR & FTNIR,<br />
Raman <strong>Spectroscopy</strong>, UV/Vis & UV/Vis/<br />
NIR, Fluorescence <strong>Spectroscopy</strong><br />
Thermal Analysis: DSC, TGA, STA, DMA<br />
Hyphenated Techniques: TG-IR, TG-MS,<br />
TG-GC/MS, DSC-Raman<br />
Organic Elemental Analysis: CHN/O,<br />
CHNS/O<br />
Consumables: Chromatography, Atomic<br />
<strong>Spectroscopy</strong>, Molecular <strong>Spectroscopy</strong>,<br />
Thermal Analysis, Elemental Analysis<br />
EcoAnalytix: Application-focused solutions<br />
to help ensure the preservation of<br />
our ecosystem and public health and<br />
safety<br />
Laboratory Services/OneSource®<br />
Facilities<br />
PerkinElmer, Inc. operates globally in 125<br />
countries.
52 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
PHOTONIS USA<br />
PHOTONIS USA<br />
Sturbridge Business Park<br />
660 Main Street<br />
Sturbridge, MA 01566<br />
TELEPHONE<br />
(508) 347-4000<br />
(800) 648-1800<br />
FAX<br />
(508) 347-3849<br />
E-MAIL<br />
sales@usa.photonis.com<br />
WEB SITE<br />
www.photonis.com<br />
NUMBER OF EMPLOYEES<br />
USA: 150<br />
Elsewhere: 900<br />
YEAR FOUNDED<br />
1937<br />
Company Description<br />
PHOTONIS is a leading developer,<br />
manufacturer, and<br />
supplier of Scientific Detector<br />
products and components<br />
for scientific and<br />
analytical instrumentation<br />
systems. We specialize in<br />
ion, electron, and photon<br />
detection with unrivaled<br />
expertise in designing and<br />
delivering standard and<br />
custom products to meet<br />
the most demanding applications.<br />
Our engineering and<br />
manufacturing expertise<br />
delivers solutions for<br />
virtually every detection<br />
application. With the PHO-<br />
TONIS worldwide manufacturing<br />
capability and support network, we can both design<br />
and manufacture your most challenging detection needs.<br />
Chief Spectroscopic Techniques Supported<br />
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Mass Spectrometry<br />
Time of Flight MS<br />
Raman <strong>Spectroscopy</strong><br />
Nuclear <strong>Spectroscopy</strong><br />
UV and X-Ray <strong>Spectroscopy</strong><br />
Charged Particle Imaging<br />
Electron Microscopy<br />
Residual Gas Analysis/Leak Detection<br />
E-Beam/X-Ray Lithography<br />
Luminescence<br />
Fluorescence<br />
Atomic Absorption<br />
Deep UV/X-Ray Optics<br />
Markets Served<br />
PHOTONIS detection products are found in most of today’s<br />
high technology-based markets, including Scientific and<br />
Analytical Instrumentation, Medical Diagnostics, Chemistry,<br />
Scientific Research, Life Sciences, Space and Geophysical Exploration,<br />
Environmental and Process Monitoring, Homeland<br />
Security, Control, and Communications.<br />
Major Products/Services<br />
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Micro Pore Optics<br />
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⦁<br />
Channeltron® Electron Multipliers<br />
MAGNUM ® Electron Multipliers<br />
Long-Life Microchannel Plates<br />
Time-of-Flight MCP Detectors<br />
MCP Detector Assemblies<br />
FieldMaster Ion Guides and Drift<br />
Tubes<br />
Glass Capillary Arrays<br />
Resistive Glass Products<br />
Electron Generator Arrays<br />
MCP-based PMTs<br />
Image Intensifier Tubes<br />
Intensified Camera Units<br />
Hybrid Photo Detectors<br />
Streak Tubes<br />
High Voltage Power Supplies<br />
Power Tubes<br />
Neutron and Gamma Detectors<br />
Glass-coated Wire<br />
Flexible Fiber Optics<br />
Facilities<br />
PHOTONIS in Sturbridge, Massachusetts<br />
manufactures Channeltron® Electron<br />
Multipliers, Microchannel Plates, MCP<br />
Detectors, Ion Guides, prototype detectors<br />
and other custom glass products. The Lancaster,<br />
Pennsylvania facility manufactures<br />
Power Tubes and other related products.<br />
PHOTONIS in Roden, Netherlands<br />
manufactures Image Intensifier Tubes,<br />
Intensified Camera Units and Hybrid Photo<br />
Detectors. PHOTONIS in Brive, France<br />
manufactures Image Intensifier Tubes and<br />
related products.
54 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
PIKE Technologies<br />
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Integrating Spheres, NIR, and Mid-IR<br />
versions for FTIR spectrometers<br />
Transmission supplies, including IR<br />
optics, and windows of all sizes and<br />
designs<br />
Automation and temperature control<br />
are available for many of our spectroscopy<br />
accessories to speed sampling and<br />
to provide precise thermal analysis<br />
Markets Served<br />
PIKE products are designed for molecular<br />
spectrometers in the petrochemical, food,<br />
forensic, biochemical, pharmaceutical,<br />
semiconductor, agriculture, and material<br />
science industries. In addition, PIKE<br />
specializes in custom design of products<br />
for specific applications. PIKE products are<br />
designed and built with craftsmanship and<br />
care to exceed customer expectations.<br />
PIKE Technologies<br />
6125 Cottonwood Drive<br />
Madison, WI 53719<br />
TELEPHONE<br />
(608) 274-2721<br />
FAX<br />
(608) 274-0103<br />
E-MAIL<br />
sales@piketech.com<br />
WEB SITE<br />
www.piketech.com<br />
NUMBER OF EMPLOYEES<br />
26<br />
YEAR FOUNDED<br />
1989<br />
Company Description<br />
PIKE Technologies was established in the summer of 1989,<br />
specializing in the development and manufacture of accessories<br />
and optical systems that enhance the performance of<br />
commercial spectrometers.<br />
PIKE concentrates on making the life of laboratory personnel<br />
easier. This is achieved through replacing traditional,<br />
tedious sampling routines with a range of innovative products<br />
and techniques.<br />
Chief Spectroscopic Techniques Supported<br />
PIKE Products are designed to work with FTIR and molecular<br />
spectrometers and are based upon the principles of transmission<br />
and reflection spectroscopy measurements. The sampling<br />
techniques offered can be divided into seven major groups:<br />
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Attenuated Total Reflectance (ATR), for analysis of liquids,<br />
pastes, and soft solid materials<br />
Diffuse Reflectance (DRIFTS), used in sampling of powders<br />
and solids<br />
Specular Reflectance, useful in thin film composition and<br />
thickness measurements<br />
Microsampling Products, FTIR microscope and beam<br />
condensers to analyze microsamples<br />
Major Products/Services<br />
⦁<br />
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MIRacle — Patented “universal” sampling<br />
accessory — Diamond, ZnSe, Ge,<br />
Si, and AMTIR crystals<br />
GladiATR and GladiATR Vision—<br />
Highest performance diamond ATR<br />
VeeMax — Patented variable angle<br />
Specular Reflection and the ATR Max<br />
used for variable depth of penetration<br />
experiments and studies<br />
A wide range of fully automated FTIR<br />
and NIR products with easy to integrate<br />
AutoPRO software<br />
Valu-Line Kits combining the most<br />
often used sampling accessories and<br />
transmission kits containing sampling<br />
holders, cells, and optics<br />
Integrating Spheres for IR and NIR<br />
Facilities<br />
PIKE Technologies is located in Madison,<br />
Wisconsin. We distribute direct to our<br />
customers worldwide and OEM worldwide<br />
for packaging with spectrometers of all<br />
manufacturers. Please call or visit our web<br />
site for additional contact and product<br />
information.
www.spectroscopyonline.com<br />
Smiths Detection Scientific<br />
DECEMBER 2009 SPECTROSCOPY CORPORATE CAPABILITIES 55<br />
Smiths Detection<br />
Scientific<br />
21 Commerce Drive<br />
Danbury, CT 06810<br />
TELEPHONE<br />
(203) 207-9700<br />
FAX<br />
(203) 207-9780<br />
E-MAIL<br />
danbury@smithsdetection.com<br />
WEB SITE<br />
www.smithsdetection.com<br />
NUMBER OF EMPLOYEES<br />
31,000<br />
Company Description<br />
Smiths Detection Scientific simplifies science by developing<br />
rapid, easy-to-use application-focused tools for cleaning<br />
validation, material, research and identification, manufacturing,<br />
industrial hygiene, and quality control.<br />
Increase the speed and reliability of your chemical analysis<br />
with solutions that include:<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
IlluminatIR II – FT-IR Accessory for Light Microscopy<br />
IdentifyIR ® – Portable FT-IR Spectrometer<br />
IONSCAN-LS ® – Ion Mobility Spectrometer<br />
FT-IR Accessories & Libraries<br />
Smiths Detection Scientific is part of the global business<br />
Smiths Group, a leading developer and manufacturer of<br />
advanced technology solutions for civil and military markets<br />
worldwide.<br />
Chief Spectroscopic Techniques Supported<br />
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Coating characterization<br />
Compound validation<br />
Consistency verification<br />
Containment studies<br />
Contamination analysis<br />
Counterfeit analysis<br />
Crystal characterization<br />
Drug precursor identification<br />
Explosives identification<br />
Failure analysis<br />
Fiber or film recognition<br />
Forensic analysis<br />
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Illicit drug identification<br />
Laminate characterization<br />
Pharmaceutical research<br />
Process chemistry<br />
Quality control<br />
Reaction monitoring<br />
Research and development<br />
Reverse engineering<br />
Soil identification<br />
White powder identification<br />
WMD identification<br />
Markets Served<br />
Smiths Detection Scientific is solely committed<br />
to providing user-focused solutions<br />
to help improve analytical practices within<br />
highly specific markets, including:<br />
⦁<br />
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Forensic Sciences<br />
Homeland Security<br />
Industrial<br />
Military<br />
Pharmaceutical<br />
Public Health Laboratories<br />
Chemical<br />
Custom<br />
Major Products/Services<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
IlluminatIR II – FT-IR Accessory for Light<br />
Microscopy<br />
IdentifyIR – Portable FT-IR Spectrometer<br />
IONSCAN-LS– Ion Mobility Spectrometer<br />
FT-IR Accessories & Libraries<br />
Facilities<br />
Smiths Detection – Danbury is a registered<br />
ISO14001:2004 company dedicated to<br />
customer satisfaction with a commitment<br />
to quality. Our quality platform is built on<br />
our Six Sigma Certification Program and<br />
our Quality Management Data System designed<br />
for consistency and quality in our<br />
products as well as continuous improvement<br />
in our business processes. In addition<br />
Smiths Detection – Danbury offers 21<br />
CFR part 11 compliant solutions, enabling<br />
our customers to meet the needs of<br />
government regulations.
56 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
Shimadzu Scientific Instruments<br />
Shimadzu Scientific<br />
Instruments<br />
7102 Riverwood Drive<br />
Columbia, MD 21046<br />
TELEPHONE<br />
800-477-1227<br />
410-381-1227<br />
FAX<br />
410-381-1222<br />
E-MAIL<br />
webmaster@shimadzu.com<br />
WEB SITE<br />
www.ssi.shimadzu.com<br />
NUMBER OF EMPLOYEES<br />
USA: 335<br />
Worldwide: 9600<br />
YEAR FOUNDED<br />
Shimadzu Scientific<br />
Instruments: 1975<br />
Shimadzu Corporation: 1875<br />
Company Description<br />
Shimadzu Scientific Instruments (SSI) is the North American<br />
subsidiary of Shimadzu Corp., headquartered in Kyoto, Japan.<br />
Founded in 1875, Shimadzu Corporation has a distinguished<br />
history of innovation built on the foundation of contributing<br />
to society through science and technology. SSI was established<br />
in 1975 to provide analytical solutions to a wide range<br />
of laboratories in the Americas. Steady and controlled growth<br />
has seen the opening of ten regional offices across the United<br />
States; a state-of-the-art Customer Training and Education<br />
Center; and, most recently, a Life Sciences Applications<br />
Laboratory in California.<br />
Chief SpectroscopicTechniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
UV-Vis<br />
FT-IR<br />
Fluorescence<br />
Atomic (AA/ICP)<br />
X-Ray (EDX/XRD/XRF)<br />
GC–MS<br />
LC–MS<br />
Markets Served<br />
Shimadzu offers more spectroscopy instrumentation, with<br />
more software and accessory options, than any other company.<br />
This flexibility enables spectroscopists in virtually any<br />
laboratory, from biotechnology, pharmaceutical, and industrial<br />
to academic, forensic, and environmental, to select the instrument<br />
best suited to their application. Shimadzu provides free<br />
technical support for the life of the instruments and encourages<br />
customer alliances to further product development.<br />
Major Products/Services<br />
UV-VIS: Shimadzu meets your needs for ruggedness, ease of<br />
use, validation and applications with a variety of UV-Vis<br />
spectrophotometers.<br />
⦁<br />
Compact, high-resolution UV-1800<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Easy-to-use UV-Mini<br />
Bioscience-oriented BioSpec-mini<br />
Life science-dedicated BioSpec-nano<br />
Single monochromator UV-2450<br />
Double-blazed, double monochromator<br />
UV-2550<br />
Research-grade UV-3600 UV-VIS-NIR<br />
SolidSpec-3700 UV-VIS-NIR<br />
FT-IR: Our robust, yet stable, FT-IR spectrophotometers<br />
deliver optimum performance,<br />
sensitivity, and reliability at an exceptional<br />
price, and we offer more of the<br />
sampling accessories you need, including<br />
an automated microscope.<br />
FLUORESCENCE: High-performance spectrofluorophotometer<br />
handles a range of<br />
applications from routine analysis to highlevel<br />
R&D.<br />
AA/ICP: High-quality spectrometers<br />
represent the ultimate in technology by<br />
delivering exceptional performance and<br />
maximum value.<br />
X-ray: Our EDX/XRF/XRD systems are<br />
packed with powerful features to provide<br />
users with versatile, easy-to-use solutions.<br />
Facilities<br />
Shimadzu’s U.S. headquarters includes<br />
customer service and technical support, as<br />
well as a customer training and education<br />
center. Ten regional facilities, strategically<br />
located around the U.S., provide customers<br />
with local sales, service, and technical<br />
support.
58 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
Specac, Inc.<br />
Company Description<br />
Specac delivers quality products engineered to meet your needs. Our accessories and systems are<br />
easy to use and built to last. From thin plastic film preparation accessories, used for routine quality<br />
checks, to sophisticated remote sampling systems for reaction monitoring.<br />
Specac is now part of Smiths Group, who acquired Specac Ltd from Graseby in 1997. Specac now<br />
employs around 55 people worldwide, with offices in the U.S. and the U.K., and a network of distributors<br />
and dealers worldwide. Smiths Group is an international company employing 16,000 people in<br />
some 50 different businesses located in the U.K., U.S., and Europe.<br />
Specac does not support chromatographic techniques.<br />
Markets Served<br />
Specac provides accurate and reliable IR and FT-IR sample handling accessories to academic,<br />
industrial, and research institutions worldwide. Specific areas include oil refineries, petrochemicals,<br />
chemical, pharmaceutical, food, observatories, military, and universities.<br />
Specac Limited<br />
River House<br />
97 Cray Avenue<br />
Orpington<br />
Kent<br />
BR5 4HE<br />
TELEPHONE<br />
01689 873134<br />
FAX<br />
01689 878527<br />
Specac, Inc.<br />
50 Sharpe Drive<br />
Cranston, RI 02920<br />
Major Products/Services<br />
Specac’s products fall into 4 areas: IR Sampling Accessories, Sample Preparation, Polarisers, and<br />
Products and Process.<br />
We can provide everything you need, from classic hydraulic presses (up to 40 ton) to handheld<br />
dies for producing smaller samples, a grinding mill or a high-temperature constant thickness film<br />
maker system — whatever type of sample you are preparing, you can be sure of a perfect reading.<br />
Our range of gas cells allows us to offer sampling solutions in a wide variety of pathlengths,<br />
volumes, construction materials, and windows.<br />
Facilities<br />
Specac moved to its current purpose-built location in 1995, based in Orpington, Kent.<br />
There has been a substantial manufacturing investment, and we have a team of optical and<br />
mechanical engineering experts using the latest in 3D CAD systems and optical design software.<br />
TELEPHONE<br />
(401) 854-5281<br />
FAX<br />
(401) 463-6206<br />
E-MAIL<br />
sales@specac.co.uk<br />
WEB SITE<br />
www.specac.com<br />
NUMBER OF EMPLOYEES<br />
USA: 3<br />
UK: 55<br />
YEAR FOUNDED<br />
1971
www.spectroscopyonline.com<br />
DECEMBER 2009 SPECTROSCOPY CORPORATE CAPABILITIES 59<br />
Spellman High-Voltage Electronics<br />
Spellman High-Voltage<br />
Electronics<br />
475 Wireless Blvd.<br />
Hauppauge, NY 11788<br />
TELEPHONE<br />
(631) 630-3000<br />
FAX<br />
(631) 435-1620<br />
E-MAIL<br />
sales@spellmanhv.com<br />
WEB SITE<br />
www.spellmanhv.com<br />
NUMBER OF EMPLOYEES<br />
1000<br />
YEAR FOUNDED<br />
1947<br />
Company Description<br />
When manufacturers around the world require high-precision,<br />
well-regulated power, one name most often comes to mind:<br />
Spellman High Voltage. Over the past 60 years, Spellman<br />
has helped innovative system developers succeed by custom<br />
designing and manufacturing the best high voltage DC power<br />
supplies for their unique requirements.<br />
Spellman’s global direct sales and technical support professionals,<br />
and our specialized sales representatives, focus on<br />
adding value over the long term. They amplify our customers’<br />
voices within Spellman, ensuring that the right people are<br />
aware, the right resources are allocated and the right<br />
response is generated.<br />
You can rely on the world’s largest and most experienced<br />
high voltage engineering staff to design the best solutions for<br />
your system requirements. World-class project teams, experienced<br />
in specific applications and technologies, are dedicated<br />
not only to new designs but also to sustaining engineering<br />
throughout the life of each product.<br />
Markets Served<br />
With the broadest range of products in our market and over<br />
1000 employees located in North America, Europe and Asia,<br />
choosing Spellman makes it possible for many customers to<br />
reduce their vendor base. Our seven integrated manufacturing<br />
facilities permit us to locate production to minimize cost and<br />
support individual customer needs. Low-cost manufacturing<br />
centers in Mexico and China provide high quality products at<br />
competitive prices. Spellman’s purchasing power and global<br />
supply chain alliances with superior vendors enables us to<br />
negotiate competitive pricing, stocking and<br />
delivery programs.<br />
C-TPAT certification reduces international<br />
shipment transit times, as well as<br />
the risk of lengthy delays due to sudden<br />
increases in border security. Lean manufacturing<br />
techniques such as value stream<br />
mapping, focused factories, mixed and<br />
single model cells, and visual control systems<br />
are some of the tools used to reduce<br />
cost and lead time.<br />
In-house expertise in sub-assembly<br />
manufacturing processes - including sheet<br />
metal fabrication, machining, welding and<br />
finishing, high voltage coil winding, printed<br />
circuit board assembly (surface mount and<br />
thru-hole) and encapsulation - increase<br />
control of quality, reduce time-to-market<br />
and permit quick reaction to design or<br />
market changes. Spellman’s quality system<br />
focuses on understanding and providing<br />
what our customers value. Lean and Six<br />
Sigma initiatives empower individuals<br />
and teams to conduct systematic root<br />
cause analyses, and implement effective<br />
corrective prevention measures. In 1994,<br />
Spellman demonstrated its long-standing<br />
commitment to rigorous standards of<br />
quality by becoming the first high voltage<br />
company to achieve ISO 9001 certification.<br />
Major Products/Services<br />
We offer power converters with well regulated<br />
outputs from
60 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
SPEX CertiPrep, Inc<br />
cement facilities, state and federal government<br />
agencies, industrial laboratories,<br />
manufacturing facilities, clinical laboratories,<br />
colleges and universities, public utilities,<br />
oil refiners, nuclear plants, wineries,<br />
wastewater and drinking water labs, and<br />
wastewater treatment plants, etc.<br />
SPEX CertiPrep, Inc.<br />
203 Norcross Ave.<br />
Metuchen, NJ 08840<br />
TELEPHONE<br />
(800) 522-7739<br />
FAX<br />
(732) 603-9647<br />
E-MAIL<br />
CRMsales@spexcsp.com<br />
WEB SITE<br />
www.spexcsp.com<br />
NUMBER OF EMPLOYEES<br />
50<br />
YEAR FOUNDED<br />
1954<br />
Company Description<br />
SPEX CertiPrep is a leading manufacturer of Certified Reference<br />
Materials (CRMs) and calibration standards for analytical<br />
spectroscopy and chromatography. We offer a full range of<br />
organic and inorganic CRMs for ICP, ICP-MS, AA, GC, GC–MS,<br />
and HPLC. We are proud to be accredited by A2LA for both<br />
Organic and Inorganic CRMs under ISO 17025:2005 and ISO<br />
Guide 34-2000. The scope of our accreditation is the most<br />
comprehensive in the industry and encompasses all our<br />
manufactured products. We also offer customers the option<br />
to create their own custom standards with quick turn-around<br />
time at no additional cost.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
ICP<br />
ICP-MS<br />
IC<br />
AA<br />
GC<br />
GC–MS<br />
HPLC<br />
ISE<br />
XRF<br />
XRD<br />
Markets Served<br />
SPEX CertiPrep supplies Certified Reference Materials to the<br />
following markets: research and development laboratories,<br />
environmental laboratories, wastewater treatment facilities,<br />
Major Products/Services<br />
SPEX CertiPrep products include aqueous<br />
and organometallic certified reference<br />
materials for ICP-MS, ICP and AA; organic<br />
standards for GC, GC–MS and HPLC; Ion<br />
Chromatography and Ion Selective Electrode<br />
Standards; Inorganic and Organic<br />
Quality Control; Fusion Fluxes for XRF; and<br />
OdorEroder. Our newest products include<br />
a RoHS/WEEE check standard and various<br />
solid reference materials. Stock items<br />
generally ship within 24–48 hours from<br />
our Metuchen, New Jersey facility. Technical<br />
customer service is available Monday<br />
through Friday 8:00 am – 5:30 pm EST by<br />
phone or Live Chat through our website<br />
at www.spexcsp.com. Look for our newly<br />
designed and updated website coming in<br />
early <strong>2010</strong>!!<br />
Facilities<br />
Our US headquarters is located in<br />
Metuchen, New Jersey. All our products<br />
are manufactured and shipped from this<br />
facility. SPEX CertiPrep, Ltd. is the European<br />
subsidiary of SPEX CertiPrep, Inc. and is<br />
located in Middlesex, England. Distributors<br />
throughout Europe support this branch.
www.spectroscopyonline.com<br />
Thermo Fisher Scientific<br />
DECEMBER 2009 SPECTROSCOPY CORPORATE CAPABILITIES 61<br />
Thermo Fisher Scientific<br />
Instruments<br />
5225 Verona Road<br />
Madison, WI 53711<br />
TELEPHONE<br />
(800) 532-4752<br />
FAX<br />
(608) 273-5046<br />
E-MAIL<br />
analyze@thermofisher.com<br />
WEB SITE<br />
www.thermo.com<br />
Company Description<br />
Thermo Fisher Scientific is the world leader in serving science,<br />
enabling our customers to make the world healthier, cleaner,<br />
and safer. Our goal is to make our customers more productive<br />
and to enable them to solve their analytical challenges,<br />
from routine testing to complex research and discovery. We<br />
offer a wide range of products including analytical instruments,<br />
equipment, reagents and consumables, software, and<br />
services for research, analysis, discovery, and diagnostics. Our<br />
manufacturing sites in the United States and Europe provide<br />
products for customers within pharmaceutical and biotech<br />
companies, hospitals and clinical diagnostic labs, universities,<br />
research institutions, and government and environmental<br />
industries.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
AA<br />
ICP<br />
ICP-MS<br />
Combustion Analyzers<br />
FT-IR<br />
FT-NIR<br />
UV-Vis<br />
Raman<br />
EDS/WDS<br />
OES<br />
XRD<br />
XRF<br />
Markets Served<br />
Our growing portfolio of products includes<br />
innovative technologies for a multitude<br />
of markets including mass spectrometry,<br />
elemental analysis, molecular spectroscopy,<br />
sample preparation, informatics, fine<br />
and high-purity chemistry production, cell<br />
culture, RNA interference analysis and immunodiagnostic<br />
testing, as well as air and<br />
water quality monitoring process control.<br />
Major Products/Services<br />
Thermo Scientific spectroscopy instruments<br />
are ideal for investigative analysis<br />
or quality control applications.<br />
<strong>Spectroscopy</strong> systems are used to determine<br />
the molecular or elemental composition<br />
of a wide range of complex samples,<br />
including liquids, solids, and gases. We offer<br />
an expansive range of techniques, such<br />
as FT-IR, FT-NIR, Infrared microsampling,<br />
Raman spectroscopy, AA, ICP, ICP-MS and<br />
ARL OES, XRD and XRF spectrometers.
62 SPECTROSCOPY CORPORATE CAPABILITIES DECEMBER 2009 www.spectroscopyonline.com<br />
WITec GmbH<br />
WITec GmbH<br />
Main Address:<br />
Lise-Meitner-Str. 6, 89081<br />
Ulm, Germany<br />
WITec Instruments Corp.,<br />
200 East Broadway Ave.,<br />
Suite 30, Maryville, TN 37804<br />
TELEPHONE<br />
+49 (0) 731 140 700<br />
USA: (865) 984-4445<br />
FAX<br />
+49 (0) 731 140 7020<br />
USA: (865) 984-4441<br />
E-MAIL<br />
info@witec.de<br />
WEB SITE<br />
www.witec.de<br />
NUMBER OF EMPLOYEES<br />
33<br />
YEAR FOUNDED<br />
1997<br />
Company Description<br />
WITec is a manufacturer of high-resolution optical and scanning<br />
probe microscopy solutions for scientific and industrial<br />
applications. A modular product line allows the combination<br />
of different microscopy techniques such as Raman, NSOM, or<br />
AFM in one instrument. The company’s product line features<br />
a Near-field Scanning Optical Microscope, using unique cantilever<br />
technology, a Confocal Raman Microscope designed<br />
for highest sensitivity and resolution, and an AFM for material<br />
research and nanotechnology. Focusing on innovations and<br />
constantly introducing new technologies, WITec is the leading<br />
expert for a vide variety of optical, structural, and chemical<br />
imaging tasks.<br />
Chief Spectroscopic Techniques Supported<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
⦁<br />
Raman <strong>Spectroscopy</strong><br />
Confocal Raman Imaging<br />
Ultrafast Confocal Raman Imaging<br />
Confocal and Near-field Fluorescence <strong>Spectroscopy</strong><br />
Upgradeable with Atomic Force and Near-field Microscopy<br />
<strong>Capabilities</strong><br />
Markets Served<br />
WITec products are delivered worldwide to academic and<br />
industrial research labs focusing on high-resolution chemical<br />
imaging and materials characterization. Areas of application<br />
for WITec’s Confocal Raman Imaging systems include Polymer<br />
Sciences, Pharmaceutics, Life Science, Geoscience, Thin Films<br />
and Coating Analysis, Semiconductors, and Nanotechnology.<br />
Major Products/Services<br />
WITec alpha300 Confocal Raman<br />
Microscope: The alpha300 R is a Raman<br />
imaging systems, focusing on high-resolution<br />
as well as high-speed spectra and<br />
image acquisition. The acquisition time<br />
for a single Raman spectrum is in the<br />
range of one millisecond or even below;<br />
thus, a complete Raman image consisting<br />
of tens of thousands of spectra can be<br />
obtained in one minute or less. Differences<br />
in chemical composition, although<br />
completely invisible in the optical image,<br />
will be apparent in the Raman image and<br />
can be analyzed with a resolution down<br />
to 200 nm.<br />
WITec alpha500 Automated Confocal<br />
Raman & Atomic Force Microscope: The<br />
alpha500 is an automated Confocal Raman<br />
and Atomic Force Microscopy System<br />
incorporating a motorized sample stage<br />
for large samples and customized multiarea/multi-point<br />
measurements. It allows<br />
nondestructive chemical imaging with<br />
Confocal Raman Microscopy as well as<br />
high-resolution topography imaging with<br />
AFM using the integrated piezo scan-stage.<br />
Both modes can be run fully automatically,<br />
guaranteeing the most comprehensive<br />
surface inspection possibilities for systematic<br />
and routine research tasks or highlevel<br />
quality control.<br />
Facilities<br />
WITec Headquarters is located in Ulm,<br />
Germany, and includes the R&D department,<br />
production, sales & marketing, and<br />
administration. WITec Instruments Corp.<br />
in Savoy, Illinois, is responsible for North<br />
American sales activities.
www.spectroscopyonline.com<br />
December 2009 <strong>Spectroscopy</strong> 24(12) 63<br />
The Baseline<br />
Group Theory and Symmetry,<br />
Part I: Symmetry Elements<br />
Group theory is the field of mathematics that includes, among other things, the treatment of<br />
symmetry. Well, it turns out that molecules have symmetry, so group theoretical principles<br />
can be applied to molecules. Because spectroscopy uses light to probe the properties of molecules,<br />
it might not be surprising that group theory has some application to spectroscopy.<br />
Here, we start a multipart discussion of symmetry and group theory.<br />
David W. Ball<br />
Symmetry is one of those things that people recognize<br />
but is hard to define. For example, most people recognize<br />
that a square is more symmetric than a rectangle,<br />
but they would have a difficult time defining why a square is<br />
more symmetric than a rectangle.<br />
For our purposes, symmetry can be defined as a sort of<br />
shape similarity. A square is more symmetric than a rectangle<br />
because all four of its sides are equal, whereas in a<br />
rectangle, only two sides are equal.<br />
However, the mathematical treatment of symmetry has<br />
more to it than that. There are certain specific operations<br />
that can be performed on an object to reorient that object in<br />
space, and if the exact same-looking shape is generated, the<br />
object has symmetry. The more of these sorts of operations<br />
that can be performed to regenerate the exact same shape<br />
in space, the “higher” the symmetry of the object. Here, we<br />
will introduce the different operations that are used to define<br />
the symmetry of an object.<br />
Rotational Symmetry<br />
Consider the square in Figure 1. One of the corners has<br />
been marked by an asterisk. If we rotate the square by<br />
90°, note that the asterisk moves position but the square<br />
remains looking like, well, a square. The resulting square<br />
looks exactly like the initial square. Consider, however, the<br />
rectangle in Figure 1. When it is rotated by 90°, it is still the<br />
same rectangle to be sure, but now it is oriented differently.<br />
It is not the same-looking rectangle in space that we started<br />
with. We say, then, that the square has a rotational axis of<br />
symmetry that the rectangle doesn’t. In this case, the symmetry<br />
axis would be going through the center of the square,<br />
right through the plane of the printed paper. Because we<br />
turned the square by one fourth of a full circle, we say that<br />
the square has a fourfold rotational axis of symmetry. (Axes<br />
of symmetry are named for the number of times an object<br />
has to rotate to return to its original starting position; in this<br />
case, the square would be rotated four times to return to its
64 <strong>Spectroscopy</strong> 24(12) December 2009 www.spectroscopyonline.com<br />
* *<br />
*<br />
starting position.) The rectangle has a<br />
twofold axis of symmetry, because we<br />
can rotate the rectangle by one half of<br />
a circle, 180° and generate a similarlooking<br />
rectangle in the same<br />
orientation.<br />
A rotational axis of symmetry is one<br />
type of symmetry element. The actual<br />
performance of the rotation by the<br />
object is called a symmetry operation.<br />
An object is said to “have a symmetry<br />
element” if the operation performed<br />
by the symmetry element yields a new<br />
shape that is oriented exactly like the<br />
original shape is oriented, even though<br />
the parts of the shape have moved. Rotational<br />
axes of symmetry are labeled<br />
as C n<br />
, with the n standing for the 1/nth<br />
of a circle the object is rotated. Hence,<br />
the square has a C 4<br />
axis of symmetry<br />
going through its center, while the<br />
rectangle does not. The square is said<br />
to have a “fourfold” axis of symmetry,<br />
and the value of four is called the order<br />
of the axis.<br />
An object can have more than one<br />
of the same type of symmetry element.<br />
For instance, coincident with the C 4<br />
axis of the square is also a C 2<br />
axis,<br />
because you can also rotate a square<br />
by one half of a circle and get the same<br />
square back. The C 2<br />
can be thought<br />
of as performing a C 4<br />
-type of rotation<br />
twice, but the C 2<br />
symmetry element<br />
is in fact a unique symmetry element.<br />
90°<br />
Figure 1: A square (top) has a symmetry element that allows it to be rotated by 90° and a similar<br />
square is generated. A rectangle does not; after 90° rotation, the long axis is vertical rather than<br />
horizontal. We say that the square has “higher” symmetry than the rectangle. The symmetry<br />
element is an axis going through center of the square, perpendicular to the page, and is labeled<br />
a C 4<br />
axis.<br />
90°<br />
The square also has some other C 2<br />
axes, as shown in Figure 2. The rectangle<br />
shares some of these axes, but<br />
not others. It is partly because of this<br />
that the square is considered higher<br />
symmetry than the rectangle — it has<br />
more symmetry elements.<br />
Reflection Symmetry<br />
Another type of symmetry element<br />
is the reflection plane, which is symbolized<br />
by the lowercase Greek letter<br />
sigma σ. This symmetry element is<br />
exactly what it sounds like: a plane that<br />
acts as a mirror, reflecting all points<br />
of a shape to the other side of the mirror.<br />
If the exact same shape oriented in<br />
space is produced, the object is said to<br />
have a reflection plane of symmetry.<br />
Figure 3 demonstrates a reflection<br />
plane of symmetry. The pentagon<br />
on top is split by a mirror that goes<br />
through the plane of the page. As is<br />
demonstrated by the indicated point, if<br />
that point is reflected to the other side<br />
of the plane, it falls back on the pentagon<br />
shape. Reflecting all points on the<br />
pentagon will end up reproducing the<br />
original pentagon, so this pentagon<br />
has a reflection plane of symmetry as a<br />
symmetry element. However, the crescent<br />
on the bottom does not have the<br />
indicated plane of symmetry, because<br />
reflecting all points on the crescent<br />
through the plane would not<br />
*<br />
regenerate the original shape. In this<br />
regard, the crescent is acting like your<br />
hands — they are reflections of each<br />
other, but not the same orientation in<br />
space. (You can verify this by putting<br />
your hands on a table palm-down and<br />
trying to superimpose your thumbs<br />
and pinkies — you won’t be able to!)<br />
Note that the plane of the page also<br />
forms a reflection plane of symmetry<br />
for both shapes in Figure 3. Each point<br />
on the shape is reflected on itself.<br />
Reflection planes are classified<br />
by whether or not they contain the<br />
rotational axis of highest order, the<br />
so-called principal axis. If a reflection<br />
plane contains the principal axis, it<br />
is called a vertical plane of symmetry<br />
and given the symbol σ v<br />
. There can be<br />
more than one vertical plane of symmetry<br />
in an object. If the reflection<br />
plane of symmetry is perpendicular<br />
to the principal axis, it is called a<br />
horizontal plane of symmetry and<br />
given the symbol σ h<br />
. If a shape has a<br />
horizontal plane of symmetry, it has<br />
only one; you cannot have more than<br />
one horizontal plane of symmetry in<br />
an object. As it is conventional to orient<br />
an object to put the principal axis<br />
in an up-and-down orientation, these<br />
descriptions of reflection planes make<br />
sense.<br />
Some shapes have vertical planes<br />
that bisect two different C 2<br />
axes. If this<br />
is the case, these vertical planes are<br />
called dihedral planes, and are given<br />
the symbol σ d<br />
. However, dihedral<br />
planes are just another type of vertical<br />
plane.<br />
Identity and Center of Inversion<br />
Likely the most simple symmetry<br />
element is identity, represented by E<br />
(from the German word “einheit”,<br />
meaning unity). Identity is the symmetry<br />
element of existence; all objects<br />
have this symmetry element, even if<br />
they have no other symmetry element.<br />
This begs the question, then: Why is<br />
this symmetry element even necessary?<br />
The answer is that it’s necessary<br />
because of the mathematical requirements<br />
of group theory. Just like the<br />
number zero is an important part of<br />
arithmetic, so is identity important in<br />
group theory and symmetry.
www.spectroscopyonline.com<br />
December 2009 <strong>Spectroscopy</strong> 24(12) 65<br />
180°<br />
180°<br />
180°<br />
i<br />
180°<br />
180°<br />
i<br />
?<br />
?<br />
180°<br />
Figure 2: The square has more C 2<br />
axes of<br />
rotational symmetry than the rectangle does.<br />
Again, the square has a higher symmetry than<br />
the rectangle.<br />
The next symmetry element is the<br />
center of inversion, symbolized by i.<br />
This symmetry operation is a reflection<br />
through a point at the center of<br />
an object in the same direction and at<br />
the same angle. Figure 4 shows a shape<br />
that has a center of inversion and a<br />
shape that does not. As its name implies,<br />
if an object does have a center of<br />
inversion symmetry element, the point<br />
that everything is reflected through is<br />
in the center of the object.<br />
Improper Rotation<br />
The last symmetry element we will<br />
consider is the most unusual. It is<br />
called an improper axis of rotation,<br />
and is denoted S n<br />
. It is a rotation by<br />
1/nth of a circle followed by reflection<br />
through a plane that is perpendicular<br />
to the rotational axis. Figure 5 demonstrates<br />
the improper rotational axis.<br />
The scroll is rotated by 180° about<br />
an axis, and then reflected through a<br />
plane that is perpendicular to that axis.<br />
Note that the original shape in space<br />
is reproduced, so this scroll has an S 2<br />
symmetry element.<br />
Improper axes of rotation can be notoriously<br />
difficult to find or visualize.<br />
Figure 3: Illustration of a reflection plane of<br />
symmetry. The pentagon on top has the given<br />
reflection of symmetry, while the crescent<br />
on the bottom does not. (The crescent does,<br />
however, have a different reflection plane of<br />
symmetry; can you find it?)<br />
Why, then, are they necessary? For the<br />
same reason that identity is defined as<br />
a symmetry element: the mathematical<br />
properties of groups require them.<br />
Point Groups<br />
As it turns out, not every random combination<br />
of symmetry elements exist<br />
for any real object. In fact, only certain<br />
combinations of symmetry elements<br />
are possible for any real three-dimensional<br />
object. These combinations are<br />
called point groups. They are called<br />
this because all of the symmetry elements<br />
of the shape will intersect at (at<br />
least) a point. While technically there<br />
are an infinite number of point groups<br />
(for example, a rotational axis can have<br />
any number as its order), only a few are<br />
scientifically relevant. For example, in<br />
crystallography, it has been demonstrated<br />
that there are only 32 different<br />
ways that a crystal can fill three-dimensional<br />
space (this is known as the<br />
crystallographic restriction theorem<br />
and applies to true crystals, not quasicrystals).<br />
Figure 4: The square has a center of inversion<br />
symmetry element, while the equilateral<br />
triangle does not.<br />
180°<br />
Rotation by ½ of a circle<br />
Reflection through plane<br />
perpendicular to axis<br />
Figure 5: Demonstration of an improper axis<br />
of rotation symmetry element. This scroll has<br />
an S 2<br />
symmetry element.
66 <strong>Spectroscopy</strong> 24(12) December 2009 www.spectroscopyonline.com<br />
v<br />
v<br />
C 2<br />
Figure 6: An object with four, and only four, symmetry elements. This combination of symmetry<br />
elements defines the C 2v<br />
point group.<br />
v<br />
+ E<br />
How does this apply to spectroscopy?<br />
Well, molecules have shapes<br />
too. Consider Figure 7. It is the same<br />
as Figure 6 but has a water molecule<br />
drawn instead of an arch. See how the<br />
water molecule has the same symmetry<br />
elements as the arch does? As such,<br />
it has the same symmetry point group:<br />
C 2v<br />
. Because of this, the water molecule<br />
will have certain properties that<br />
it shares with the arch. For example,<br />
the electrons in the water molecule are<br />
imbalanced in such a way that the molecule<br />
has a dipole moment. If the arch<br />
in Figure 6 were composed of electron<br />
density, it too, would have a dipole<br />
moment. Because the shape of the molecule<br />
is dictated by electronic wavefunctions,<br />
it should come as no surprise<br />
that the wavefunctions will have<br />
C 2v<br />
symmetry as well. <strong>Spectroscopy</strong> is<br />
the interaction of light with wavefunctions,<br />
so symmetry ultimately becomes<br />
very important in spectroscopy. But we<br />
have a ways to go before we can consider<br />
wavefunctions.<br />
In our next installment, we will find<br />
out what a mathematical group is and<br />
how these symmetry elements do indeed<br />
satisfy the definition of a group.<br />
Stay tuned . . .<br />
H<br />
v<br />
OC 2<br />
+ E<br />
H<br />
Figure 7: The water molecule has the same symmetry elements as the arch in Figure 6, so it has<br />
the same symmetry point group and will have similar properties.<br />
David W. Ball is a<br />
professor of chemistry at<br />
Cleveland State University<br />
in Ohio. Many of his<br />
“Baseline” columns have<br />
been reprinted in book<br />
form by SPIE Press as The<br />
Basics of <strong>Spectroscopy</strong>, available through<br />
the SPIE Web Bookstore at www.spie.org.<br />
Another book, Field Guide to <strong>Spectroscopy</strong><br />
(published in May 2006), is available from<br />
SPIE Press. He can be reached at d.ball@<br />
csuohio.edu; his website is<br />
academic.csuohio.edu/ball.<br />
Consider the arch in Figure 6. It<br />
has four, and only four, symmetry<br />
elements, which are superimposed<br />
on the arch: it has the E identity element,<br />
a C 2<br />
axis of rotation, and two<br />
different planes of reflection (one<br />
of which is arbitrarily labeled with<br />
a prime). That’s all, nothing else.<br />
These four symmetry elements constitute<br />
a mathematical group labeled<br />
C 2v<br />
(spoken as “sea-two-vee”). By<br />
virtue of having this point group,<br />
this shape will have certain physical<br />
properties.<br />
For more information on<br />
this topic, please visit:<br />
www.spectroscopymag.com/ball
www.spectroscopyonline.com<br />
December 2009 <strong>Spectroscopy</strong> 24(12) 67<br />
Focus on Quality<br />
Are You Getting Value From Your<br />
Spectrometer?<br />
Getting the best business value from a spectrometer requires knowledge of the instrument<br />
and its operating abilities, any attachments, the sample including sampling procedure and<br />
presentation, and the software. All of these elements must be pulled together by a skilled<br />
and knowledgeable spectroscopist. Unfortunately, this is not always the case in many<br />
organizations.<br />
R.D. McDowall<br />
In a dark, dark cupboard far, far away from the boss’s prying<br />
eyes, somewhere in your laboratory, is usually that<br />
spectrometer you wish you’d never bought. It was purchased<br />
at phenomenal expense and with great promise but it<br />
did not match reality when used operationally. So over time,<br />
alternative analytical procedures have been developed or<br />
you stick with the existing ones that the new instrument was<br />
meant to replace and you push the spectrometer into the<br />
cupboard and hope nobody notices. We’ve all done this at<br />
some time in our careers, mainly because we did not specify<br />
our requirements in sufficient detail or understand exactly<br />
why we were purchasing the system. Provided that we learn<br />
from the experience and don’t repeat it, we know that we<br />
should get better at instrument selection by documenting<br />
our user needs in the first place. Hiding an instrument from<br />
view keeps the management heat from you but does not assuage<br />
your conscience. This is the most obvious case of poor<br />
instrument selection.<br />
However, the purpose of this “Focus on Quality” installment<br />
is to look at what happens after you have purchased<br />
a system and determine the factors you need to get right<br />
to enable the system to deliver what was promised. This is<br />
especially so for molecular spectrometers such as infrared,<br />
near infrared (NIR), and Raman instruments, which offer<br />
the potential for great business benefit but often can fail<br />
to deliver. During laboratory audits that I have conducted<br />
in the past year, I have seen examples where spectrometers<br />
have failed to meet their full expectation and potential.<br />
Therefore, I want to discuss with you some of the main<br />
points that I think need to be considered to get the most out<br />
of your spectrometers and save resources at the same time.<br />
The Promise: Taking the Laboratory to the Sample<br />
Molecular spectroscopy (for example, IR, NIR, and Raman)<br />
is an analytical technique that promises rapid identity<br />
verification or qualitative analysis of most chemicals by<br />
nondestructive testing, often in situ. Furthermore, it also is<br />
capable of quantitative analysis using chemometric models<br />
contained in the instrument software, provided that the<br />
system has been correctly set up. In both modes, it is quicker<br />
than the alternative of destructive testing that occurs in<br />
conventional quality control laboratories where production<br />
needs to wait while the laboratory checks if the material<br />
meets the appropriate specification.<br />
The basis of a spectrometric verification test, often carried<br />
out in a warehouse, is that the supplier of the material<br />
has tested and certified the material against your specification<br />
and all you are doing is identity confirmation. However,
68 <strong>Spectroscopy</strong> 24(12) December 2009 www.spectroscopyonline.com<br />
there is the ability to use spectroscopic<br />
analysis to differentiate chemicals<br />
with the same structure but different<br />
physical properties — for example, differentiating<br />
different particle sizes of<br />
microcrystalline cellulose. However,<br />
to be successful, a library of spectra<br />
needs to be built up and where necessary,<br />
the postspectrum analysis models<br />
need to be established as part of the<br />
overall analytical procedure and then<br />
the overall analytical procedure must<br />
be validated.<br />
If the procedure is set up correctly, it<br />
can save a company a lot of money and<br />
time and avoid errors. For example, if a<br />
system is installed in a goods-inwards<br />
warehouse, as the containers of material<br />
come off the delivery truck, they<br />
can be sampled and tested almost immediately.<br />
If the identity is wrong, the<br />
containers can be loaded back on the<br />
track and returned to the supplier. The<br />
company has not paid for the shipment<br />
and the material has not been<br />
taken through a long and expensive<br />
QC testing process before the error<br />
has been found. Thus, there is an immediate<br />
benefit on company cash flow.<br />
Furthermore, it can enable a just-intime<br />
approach to manufacturing and<br />
hold less stock, further improving its<br />
cash position. As it can differentiate<br />
between polymorphs of the same compound,<br />
it also can be used to detect<br />
counterfeit products or subtle changes<br />
in the manufacturing process of the<br />
compound.<br />
When these spectroscopic techniques<br />
are used for quantitative analysis,<br />
there is the possibility to determine<br />
the purity of a material, either as a<br />
raw material or a finished product as<br />
well as large levels of contaminants or<br />
impurities (down to ~1%). Also, many<br />
users of spectrometers don’t realize<br />
the wider benefits of the technique as<br />
the instrument gathers much data that<br />
are unused: for example, moisture can<br />
be determined simultaneously and<br />
time saved by avoiding a separate Karl<br />
Fischer test. With the rise of counterfeit<br />
goods, molecular spectroscopy<br />
is being used both qualitatively and<br />
quantitatively to analyze suspected<br />
goods and compare with the genuine<br />
article. The ability to achieve analyses<br />
such as these requires that the system<br />
is set up correctly. However, to reach<br />
this spectroscopic nirvana, the laboratory<br />
must overcome some obstacles<br />
that might not always be considered<br />
and hence, the predestined journey to<br />
that dark, dark cupboard.<br />
However, to reach<br />
this spectroscopic<br />
nirvana, the laboratory<br />
must overcome<br />
some obstacles that<br />
might not always<br />
be considered and<br />
hence, the predestined<br />
journey to<br />
that dark, dark<br />
cupboard.<br />
But Often Reality Does Not<br />
Match the Promise<br />
So the theory and promise are great,<br />
but what happens in reality? The workflow<br />
goes something like this after the<br />
selection and purchase of the instrument<br />
(any similarity to your laboratory<br />
is merely coincidental):<br />
• You will have written down your requirements<br />
for the system and have<br />
a good understanding of what analyses<br />
it will be undertaking when operational.<br />
You’ll have compared the<br />
instruments available on the market<br />
with your specification and made<br />
the selection based upon fit to requirements,<br />
ease of use, price versus<br />
budget, and support by the potential<br />
vendor. Why are pigs flying around<br />
my office as I write this section?<br />
• The selected system is delivered by<br />
the vendor to your laboratory.<br />
• In a minority of cases, mainly regulated<br />
laboratories, the system will sit<br />
in the boxes for three to six months<br />
as the spectroscopists do not have<br />
time to validate the system. In the<br />
majority of cases, we will move immediately<br />
onto the next phase of the<br />
process.<br />
• The vendor’s service engineer will<br />
unpack the system, place it in the<br />
location where it will be used, install<br />
the components including the software<br />
and any sampling attachments<br />
purchased, and then integrate them<br />
into a system.<br />
• The service engineer will then test<br />
the system to be confident that it<br />
works from the vendor’s perspective.<br />
There will be varying degrees of formality<br />
at this stage depending if the<br />
laboratory is regulated or not and<br />
how much the company has paid for<br />
this part of the service.<br />
• Finally, the service engineer will<br />
hand the system over to the laboratory<br />
as now it is working from the<br />
vendor’s perspective.<br />
This part of the workflow is shown<br />
in the top half of Figure 1. This is the<br />
easy bit and you are now the proud<br />
owner of a brand spanking new spectrometer<br />
that has been commissioned<br />
by the vendor! So all you have established<br />
at this stage of the process is that<br />
the instrument and the other system<br />
components meet the vendor’s specifications.<br />
However, this does not mean<br />
that your analytical procedures or the<br />
software analysis models used in them<br />
have been established or validated, nor<br />
does it mean they are usable.<br />
So what are you going to do now?<br />
Establish or transfer and validate<br />
existing analytical procedures and<br />
methods using the new system. Alternatively,<br />
you will need to develop<br />
and validate new ones. You will probably<br />
need to configure the software<br />
to do what you want and spend time<br />
building the spectroscopic library if<br />
you want to perform identity tests.<br />
Furthermore, you may need to develop<br />
the chemometric models if you need<br />
to interpret the spectra acquired from<br />
sample analysis if performing quantitative<br />
analysis. Of course, this work<br />
has all been planned in advance and<br />
you have allowed time for all of these<br />
activities? Here’s where the fun starts.<br />
You are now at a crossroads with two<br />
paths ahead of you, one to the left<br />
and the other to the right. Where are
www.spectroscopyonline.com<br />
December 2009 <strong>Spectroscopy</strong> 24(12) 69<br />
Validation delay<br />
for some<br />
regulated<br />
laboratories<br />
No planning to<br />
get the system<br />
operational<br />
Instrument fails<br />
to deliver<br />
promise<br />
Relocate<br />
instrument to<br />
dark cupboard<br />
we going? The signpost for the righthand<br />
path reads “Heaven” and for the<br />
left-hand path it says “Hell.” Reading<br />
the guidebook, we find that Heaven is<br />
the spectroscopic nirvana where the<br />
system provides business benefits and<br />
is used well. Conversely, Hell closely<br />
resembles the dark, dark cupboard in<br />
your laboratory that you use to hide<br />
your mistakes. Are we going to turn<br />
left or right?<br />
Write user<br />
requirements<br />
(DQ) and select<br />
instrument<br />
Order<br />
instrument and<br />
take delivery<br />
Vendor unpacks<br />
and installs<br />
instrument and<br />
components<br />
Vendor<br />
commissioning<br />
and hand over<br />
to user<br />
Figure 1: Process flows for implementation of a spectrometer.<br />
Planning to use<br />
the instrument<br />
Validation of<br />
analytical<br />
procedures and<br />
software models<br />
Effective<br />
operational use<br />
of the system<br />
There are a number of factors that<br />
could influence which path you will<br />
eventually take. Listed below are some<br />
of the major issues to consider along<br />
with a brief description of each. How<br />
many of these will apply to your laboratory<br />
will depend upon how you will<br />
use the system.<br />
• Defined purpose for the spectrometer:<br />
You will have done this by writing<br />
down your requirements used to<br />
select the instrument. However, have<br />
you captured all of the ways you will<br />
use the instrument or just the main<br />
one? Just documenting the user<br />
needs does not ensure that the system<br />
will deliver it. So you will need<br />
to know the operational limits of the<br />
instrument — will you be working<br />
close to any limits?<br />
• Analytical technique and procedure:<br />
The procedure is documented and<br />
has been validated is a given to ensure<br />
that the results are scientifically<br />
sound. However, how are you using<br />
the instrument? Is the method qualitative<br />
or quantitative? Does it use<br />
transmittance or reflectance mode?<br />
• Sampling and the container that will<br />
be used will be either established or<br />
must be investigated as well as the<br />
way the sample is presented to the<br />
instrument.<br />
• The use of any attachments used in<br />
an analysis,such as an autosampler<br />
or a fiber-optic probe, should be understood<br />
• Software, including the development<br />
of any chemometric models used to<br />
analyze or interpret acquired spectra<br />
or reference library generation and<br />
maintenance, will be known and<br />
understood by the developer<br />
Unfortunately, as you failed to plan<br />
for this work, you have just turned<br />
onto the left-hand path. Furthermore,<br />
you have just been joined on your journey<br />
by the devil’s disciple: laboratory<br />
management! The common management<br />
mantra is get the instrument<br />
working, and now (I could say yesterday<br />
but do not want to spoil your day<br />
so early into this column). The rational<br />
is understandable, as there has been<br />
a large investment in purchasing the<br />
system and a return on investment is<br />
required for senior management. However,<br />
the old maxim “failing to plan is<br />
planning to fail” rears its ugly head at<br />
this point, and the spectrometer is on<br />
the downward spiral to that dark, dark<br />
cupboard.<br />
What Do We Need to Achieve the<br />
Promise?<br />
The first thing to remember is that<br />
for many applications, spectrometers<br />
do not simply come with on buttons.
70 <strong>Spectroscopy</strong> 24(12) December 2009 www.spectroscopyonline.com<br />
0.48<br />
0.46<br />
0.44<br />
0.42<br />
0.40<br />
Normal jar<br />
0.38<br />
0.36<br />
Absorbance<br />
0.34<br />
0.32<br />
0.30<br />
0.28<br />
0.26<br />
22-mm vial<br />
0.24<br />
0.22<br />
0.20<br />
0.18<br />
5000 4900 4800 4700 4600 4500 4400 4300 4200 4100 4000<br />
Wavenumber (cm -1 )<br />
Figure 2: NIR analysis of aureomycin showing the influence of the sample container on the spectrum. (C. Burgess, personal communication.)<br />
There is more to using the instrument<br />
and system effectively than<br />
that. The purchase, installation, and<br />
vendor commissioning phases of the<br />
work are relatively straightforward<br />
as we can see from Figure 1. The<br />
problems come when a laboratory<br />
wants to use the system for a specific<br />
analytical procedure that requires<br />
the spectrometer and the software<br />
to do more than just print a spectral<br />
scan. We will consider just a few of<br />
the factors that will influence the<br />
path you will take with your spectrometer.<br />
Of the critical factors needed to<br />
reach the promise offered by spectroscopy,<br />
we will discuss the following<br />
ones:<br />
• Instrument capability: What can<br />
the instrument can do versus the<br />
job you want it to do? Are the two<br />
congruent?<br />
• Software skills: Understanding<br />
what the software can do and its<br />
limitations for your specific analytical<br />
applications and chemometric<br />
models.<br />
• Accessories: Do you know how to<br />
use them and what impact they<br />
have on the resulting spectra?<br />
• Sample presentation: Putting the<br />
sample in a suitable container<br />
before analysis is always critical<br />
to the outcome of any analytical<br />
procedure and then presenting the<br />
sample to the instrument.<br />
If we return to the situation in<br />
which a spectrometer is to be used to<br />
verify the identity of chemicals entering<br />
a warehouse, we will need to<br />
generate a spectral library that will<br />
use the instrument and the software.<br />
The amount of time that you will<br />
need will depend upon the amount<br />
of discrimination you require. For<br />
example, if you want to discriminate<br />
lactose from methylene chloride,<br />
you will only require one or two<br />
sample spectra of each compound.<br />
For materials that are more closely<br />
related then, you will need to use up<br />
to 30 batches from the same supplier<br />
who used the same manufacturing<br />
process for each chemical. The<br />
reason for this is that differences<br />
in the manufacturing process over<br />
time will result in small changes in<br />
spectra. To ensure good discriminatory<br />
power of the instrument, the library<br />
must have sufficient examples.<br />
You can build a library with fewer<br />
samples but you will lose discrimination.<br />
If you decide to go down this<br />
route, consider what could happen if<br />
a mistake were made and the wrong<br />
material accepted.<br />
Taking the library-development<br />
discussion further, if very closely related<br />
material must be discriminated,<br />
then chemometric models, using<br />
partial least squares (PLS), principal<br />
components regression (PCR), or soft<br />
independent modeling of class analogy<br />
(SIMCA) analysis as examples,<br />
must be developed and validated.<br />
These will take correspondingly<br />
more time, and the complex ones<br />
can require 3–9 months before they<br />
are fully developed, validated, and<br />
operational. The problem is that<br />
management needs to be aware of the<br />
time needed to do this and plan<br />
accordingly.
www.spectroscopyonline.com<br />
December 2009 <strong>Spectroscopy</strong> 24(12) 71<br />
Therefore, for qualitative analysis,<br />
the message is: You need to plan for<br />
some or all of the following questions:<br />
• What you will use the library to<br />
identify?<br />
• How many compounds will be entered<br />
in the library?<br />
• How closely related chemically are<br />
the compounds?<br />
• How many batches do you need for<br />
each chemical?<br />
• Do you need to consider chemometric<br />
models?<br />
So far, we have just looked at factors<br />
influencing the library. Another<br />
factor in the mix will be if sample<br />
accessories for the spectrometer are<br />
used in an analytical procedure:<br />
• Autosampler for vials, powders, or<br />
tablets<br />
• Liquid sipper<br />
• Diffuse reflectance module<br />
• Remote fiber-optic probes for either<br />
solids or liquids<br />
Accessory choice can be critical, and<br />
when each is used in an analytical procedure,<br />
it can influence the outcome.<br />
Therefore, accessory choice needs to be<br />
understood. The choice of accessory or<br />
accessories will impart their own effects<br />
on the spectra obtained by the instrument<br />
and therefore, the laboratory<br />
must know which ones will be used<br />
at the beginning of method development<br />
so that the library or model can<br />
be built using them from the start and<br />
avoid repeating work unnecessarily.<br />
Consider also the method: How<br />
robust or accurate does the procedure<br />
have to be as the users of the procedure<br />
might not be spectroscopists or even<br />
analytical scientists? For example,<br />
there is always a balance between accuracy<br />
and robustness of the method.<br />
There can be many reasons for this<br />
but one is based upon the beam size of<br />
the instrument used in the procedure,<br />
which illustrates the need to know<br />
and understand this relationship. If<br />
you want a robust assay then typically<br />
a larger beam size is used, but this is<br />
at the cost of the accuracy of the result.<br />
Conversely if you want accuracy<br />
a smaller beam size can be used but<br />
at the cost of method robustness. In<br />
turn, this decision can result in more<br />
work on developing a library of the<br />
model used in the assay. Does this<br />
matter? Only you can decide based<br />
upon your analytical needs but the<br />
point I am making is that you need to<br />
understand how the instrument and<br />
software operate so that you can make<br />
an informed decision: Know the performance<br />
characteristics and operating<br />
envelope of the instrument you are<br />
using.<br />
How the sample is presented to<br />
the instrument is also important and<br />
is shown in Figure 2. The standard<br />
sample jars used for QC analysis were<br />
suggested for use with a new NIR spectrometer<br />
to be used for sample identification<br />
in a warehouse. When sample<br />
jars were checked, there was a high<br />
background caused by the curvature of<br />
the bottom of the jar, which dispersed<br />
the light beam. This is shown as the<br />
blue line in Figure 2. A 22-mm vial was<br />
better suited to the analysis as the base<br />
of the container was flat and the glass<br />
thinner than the standard jar, resulting<br />
in lower absorbance losses. As can be<br />
Trained user<br />
User<br />
continuum<br />
Figure 3: Diagram of the spectrometer user continuum.<br />
Instrument<br />
capability<br />
Use of<br />
instrument<br />
accessories<br />
Sample<br />
presentation<br />
Figure 4: Skills of an expert spectroscopist.<br />
Software<br />
knowledge<br />
Spectroscopist<br />
(expert user)<br />
Development<br />
of analytical<br />
methods<br />
seen in Figure 2, with the red line, the<br />
resulting spectrum has a lower background<br />
and shows more detail than<br />
using the standard jar. Interestingly,<br />
which container did the laboratory<br />
select for their sample container, the<br />
jar or the vial? Yes, you guessed right,<br />
it was the jar. Not for scientific reasons,<br />
but mainly for cost, as the vials were<br />
more expensive than the vials and<br />
they did not wish to modify existing<br />
working practices. Furthermore, the<br />
compounds in the spectral library<br />
were relatively divergent and therefore,<br />
the spectral detail obtained from using<br />
the vial was not needed. However, if<br />
the spectral library is increased and<br />
closely related compounds needed to<br />
be identified, this changes the whole<br />
approach. The downside of the decision<br />
is that the vial probably will be<br />
needed for high-resolution work and<br />
the library would need to be completely<br />
regenerated and validated. The<br />
message of the sample container saga<br />
is that you must think through your<br />
Chemometric<br />
models<br />
Spectroscopic<br />
knowledge<br />
Validation of<br />
analytical<br />
methods<br />
Expert user
72 <strong>Spectroscopy</strong> 24(12) December 2009 www.spectroscopyonline.com<br />
use of the spectrometer carefully and<br />
to plan ahead as much as possible.<br />
This is not an all-inclusive list of<br />
factors that can influence the use of a<br />
spectrometer. Some of the others are<br />
• Interoperability between instruments<br />
from the same vendor<br />
• Interoperability between instruments<br />
from different vendors<br />
• Interchangeable custom spectral<br />
libraries<br />
• Library maintenance over time<br />
• Use of third-party software<br />
Key to a Successful Solution Is an<br />
Expert User<br />
We have discussed a number of technical<br />
and scientific issues surrounding<br />
the effective deployment of a<br />
spectrometer but we have omitted the<br />
one key factor that will ensure success<br />
by integrating all of these factors<br />
together: an expert user. The decision<br />
of this debate is who is going to drive<br />
the instrument? This, in my view, will<br />
determine if you are going to be successful<br />
or if the dark cupboard will<br />
loom large in your thoughts.<br />
To understand how a spectrometer<br />
can be used effectively, it is important<br />
to understand the continuum of users<br />
of a system, and this is shown simply<br />
in Figure 3. We have on the left-hand<br />
side of the continuum a trained user<br />
or operator who would follow a set of<br />
instructions to perform a method but<br />
perhaps without understanding the<br />
technical issues of the instrument. On<br />
the right-hand side we have the expert<br />
user who understands the technical<br />
issues and can develop and validate<br />
methods for the trained users to perform.<br />
These are the extremes of the<br />
continuum. In the middle of the continuum<br />
there may be users who have<br />
more technical understanding of the<br />
system and others who are analytical<br />
scientists but have had little training<br />
in the instrument other than that<br />
offered by the service engineer augmented<br />
by reading the manuals. So<br />
if you want to develop complex spectroscopic<br />
methods, who will you be<br />
calling (as a clue it will not be Ghostbusters)?<br />
That’s right, the expert user!<br />
It was the lack of these individuals<br />
that caused me to write this column in<br />
the first place when I was auditing two<br />
laboratories.<br />
Let us look in a little more detail<br />
at the skills this group should have<br />
for effective development of spectroscopic<br />
methods. This is shown diagrammatically<br />
in Figure 4.<br />
The issue in a climate of strict cost<br />
control: Do you invest in the skills of<br />
an expert spectroscopist who understands<br />
the theory of the technique,<br />
knows the instrument and its capabilities,<br />
and how to use the accessories<br />
effectively, along with the appropriate<br />
software skills? Or do you use a<br />
generalist user? To get the most from<br />
your instrument and software, you<br />
will need a spectroscopist with some<br />
or all of the skills shown in Figure<br />
4. In the current economic climate,<br />
senior management often does not<br />
understand this and will cut specialists<br />
and aim for generalists, which is<br />
a mistake in my view. Another skill<br />
that is required by the spectroscopist<br />
is management of expectations, as it<br />
is clear from reading this column that<br />
you will not be able to roll out a complex<br />
analytical procedure in 5 min.<br />
Keeping management aware of the<br />
timeframes required is important.<br />
<strong>Spectroscopy</strong> has great potential<br />
to save time and money and the scientists<br />
who can deliver this may not<br />
be retained by an organization. So if<br />
you don’t have this in-house, it could<br />
be outsourced either from a specialist<br />
consultancy or from the instrument<br />
vendor. Regardless of the source<br />
of skill, a laboratory will need this<br />
knowledge and skill if a laboratory is<br />
to realize fully the benefits of investing<br />
in spectroscopic analysis.<br />
Summary<br />
We have looked at some of the factors<br />
necessary for effective and efficient<br />
deployment of spectroscopic methods<br />
of analysis within an organization.<br />
The key element is that an expert<br />
spectroscopist is critical for success.<br />
How you get this expertise (internal<br />
or external available) is up to the<br />
organization. However, specialist<br />
user expertise is the critical success<br />
factor to achieve the promise of spectrometry<br />
and get the most value and<br />
return on investment from your spectrometer.<br />
References<br />
(1) ASTM E 1790–04; Standard Practice<br />
for Near Infrared Qualitative Analysis<br />
(2004).<br />
(2) ASTM E 2056–04; Standard Practice<br />
for Qualifying Spectrometers and<br />
Spectrophotometers for Use in Multivariate<br />
Analyses, Calibrated Using<br />
Surrogate Mixtures (2004).<br />
(3) European Pharmacopeia 5.0, 2005;<br />
Section 2.2.40 Near-Infrared Spectrophotometry.<br />
(4) United States Pharmacopeia XXXII,<br />
2009 General Chapter Near-<br />
Infrared Spectrophotometry<br />
(5) Guidelines for the development and<br />
validation of Near Infrared (NIR) spectroscopic<br />
methods; Pharmaceutical<br />
Analytical Sciences Group (PASG)<br />
October 2001 (http://www.pasg.org.<br />
uk/NIR/NIR.htm).<br />
(6) Note for Guidance on the use of Near<br />
Infrared spectroscopy by the pharmaceutical<br />
industry and the data required<br />
for new submissions and variations;<br />
CPMP/QWP/3309/01, February<br />
2003 (www.emea.europa.eu/pdfs/<br />
human/qwp/330901en.pdf).<br />
R.D. McDowall<br />
is principal of Mc-<br />
Dowall Consulting<br />
and director<br />
of R.D. McDowall<br />
Limited, and “Questions<br />
of Quality” column<br />
editor for<br />
LCGC Europe,<br />
<strong>Spectroscopy</strong>’s sister magazine. Address<br />
correspondence to him at 73 Murray<br />
Avenue, Bromley, Kent, BR1 3DJ, UK.<br />
For more information on<br />
this topic, please visit:<br />
www.spectroscopymag.com/adar
www.spectroscopyonline.com<br />
December 2009 <strong>Spectroscopy</strong> 24(12) 73<br />
Volume 24, 2009<br />
Annual Editorial Index<br />
AUTHORS<br />
A<br />
Adar, Fran. “FT-IR and Raman: A Synergism, Not Competing<br />
Technologies,” in Molecular <strong>Spectroscopy</strong> Workbench.<br />
October, p. 16.<br />
Adar, Fran. “Raman <strong>Spectroscopy</strong> for Biomedical Applications,”<br />
in Molecular <strong>Spectroscopy</strong> Workbench. March, p.<br />
26.<br />
Adar, Fran. “Raman <strong>Spectroscopy</strong> of Carbon — More Information<br />
Than You Would Think,” in Molecular <strong>Spectroscopy</strong><br />
Workbench. February, p. 28.<br />
Adar, Fran; Lee, Eunah; and Whitley, Andrew. Transmission<br />
Raman Offers Improved Quantitation of Pharmaceutical<br />
Solids. Raman Technology for Today’s Spectroscopists, June,<br />
p. 26.<br />
Akao, Ken-ichi. See Larsen, Richard A.<br />
Almeida, Manuel. See Mahar, Maura.<br />
Asa, Darwin. High Performance Mass Spectrometry for<br />
Small Molecule and Protein Applications. Current Trends<br />
in Mass Spectrometry, May, p. 30.<br />
Athanas, Michael. See Sarracino, David.<br />
Bol´shakov, Alexander; Yoo, Jong H.; Liu, Chunyi; and<br />
Russo, Richard. Discrimination of Complex Substances<br />
with Laser-Induced Breakdown <strong>Spectroscopy</strong>. October, p.<br />
36.<br />
Botonjic-Sehic, Edita; Brown, Chris W.; Lamontagne, Marc;<br />
and Tsaparikos, Mary. Forensic Application of Near-Infrared<br />
<strong>Spectroscopy</strong>: Aging of Bloodstains. February, p. 42.<br />
Bowerbank, Christopher R. See Later, Douglas W.<br />
Boyle, Ross. See Lowry, Steve.<br />
Bradley, Mike. See Lowry, Steve.<br />
Briggs, Jenni. See Feustel, Manfred.<br />
Brown, Chris W. See Botonjic-Sehic, Edita.<br />
Brown, Peter. See Mahar, Maura.<br />
B<br />
Ball, David W. “Auger <strong>Spectroscopy</strong>,” in The Baseline. June,<br />
p. 14.<br />
Ball, David W. “Color,” in The Baseline. September, p. 16.<br />
Ball, David W. “Group Theory and Symmetry, Part I: Symmetry<br />
Elements,” in The Baseline. December, p. 63.<br />
Ball, David W. “The Seven Base Units, Part I,” in The Baseline.<br />
January, p. 22.<br />
Ball, David W. “The Seven Base Units, Part II,” in The Baseline.<br />
April, p. 14.<br />
Becker, Christopher; Fernandez-Lima, Francisco A.; and<br />
Russell, David H. Ion Mobility-Mass Spectrometry: A<br />
Tool for Characterizing the Petroleome. April, p. 38.<br />
Bluck, Les, and Volmer, Dietrich A. The Role of Naturally<br />
Occurring Stable Isotopes in Mass Spectrometry, Part II:<br />
The Instrumentation. February, p. 50.<br />
Bluck, Les, and Volmer, Dietrich A. The Role of Naturally<br />
Occurring Stable Isotopes in Mass Spectrometry, Part III:<br />
Small Gas Molecule Calculations. September, p. 34.
74 <strong>Spectroscopy</strong> 24(12) December 2009 www.spectroscopyonline.com<br />
Network. February, p. 58.<br />
Churley, Melissa. See Latiff, Aishah.<br />
Curtis, Matthew. See Sparkman, O.<br />
David.<br />
D<br />
Dalrymple, Dave. See Lowry, Steve.<br />
Davies, Gavin. See Murphy, Terry.<br />
De Lucia Jr., Frank C.; Gottfried, Jennifer<br />
L.; Munson, Chase A.; and<br />
Miziolek, Andrzej. Current Status of<br />
Standoff LIBS Security Applications<br />
at the United States Army Research<br />
Laboratory. June, p. 32.<br />
Dolic, Vesna. See Dulude, Jerry.<br />
Dong, Jing. See Yin, Liangliang.<br />
Downs, Robert T. See Lowry, Steve.<br />
Duchoslav, Eva. See Simons, Brigitte.<br />
Dulude, Jerry, and Dolic, Vesna. Optimizing<br />
Productivity for Environmental<br />
Applications of ICP. Application of<br />
ICP & ICP-MS Techniques for Today’s<br />
Spectroscopist, November, p. 16.<br />
Burrell, Michael C. See Lesaicherre,<br />
Marie.<br />
Busch, Kenneth L. “Development of<br />
Mass Spectrometry in the United<br />
States: The First 50 Years,” in Mass<br />
Spectrometry Forum. March, p. 18.<br />
Busch, Kenneth L. “Higher Resolution<br />
Mass Analysis in Inductively Coupled<br />
Plasma–Mass Spectrometry,” in<br />
Mass Spectrometry Forum. January,<br />
p. 30.<br />
Busch, Kenneth L. “Ion Lenses,” in<br />
Mass Spectrometry Forum. September,<br />
p. 20.<br />
Busch, Kenneth L. A Mass Spectrometry<br />
Glossary. Current Trends in Mass<br />
Spectrometry, October, p. 10.<br />
Busch, Kenneth L. “Pressure and Vacuum:<br />
Not Really Trivial,” in Mass<br />
Spectrometry Forum. November, p.<br />
16.<br />
Busch, Kenneth L. “Sampling in Mass<br />
Spectrometry,” in Mass Spectrometry<br />
Forum. July, p. 14.<br />
C<br />
Cai, Changqun; Chen, Xiaoming; and<br />
Gong, Hang. Interaction of Indigo<br />
Carmine with Nucleic Acids in the<br />
Presence of Cetyltrimethylammonium<br />
Bromide: Spectral Studies<br />
and the Confirmation of Combined<br />
Points. November, p. 34.<br />
Castro-Perez, Jose. See Yu, Kate.<br />
Chakraborty, Asish; Xie, Hongwei;<br />
Skilton, St John; Gebler, John C.;<br />
and Chen, Weibin. Improving the<br />
Analytical Workflow for Protein<br />
Biopharmaceutical Characterization<br />
with a Novel LC–MS System Solution.<br />
Current Trends in Mass Spectrometry,<br />
July, p. 26.<br />
Chamberland, Martin; Farley, Vincent;<br />
Lagueux, Philippe; and Villemaire,<br />
André. Chemical Warfare Agent<br />
Spectral Imaging for Real-Time Identification<br />
and Localization. Homeland<br />
Security, April, p. 20.<br />
Champion, Matthew. See Scott, Greg.<br />
Chen, Shizhong. See Yin, Liangliang.<br />
Chen, Weibin. See Chakraborty, Asish<br />
B.<br />
Chen, Xiaoming. See Cai, Changqun.<br />
Chen, Yougen. See Yu, Kate.<br />
Cheng, Cungui; Xiong, Wei; Tian,<br />
Yumei; and Zhang, Changjiang. A<br />
Novel Recognition of Three Kinds of<br />
Sibling Plants Using FT-IR with Continuous<br />
Wavelet Feature Extraction<br />
Combined with an Artificial Neural<br />
E<br />
Evans, Megan. 57th ASMS Conference<br />
Review. Current Trends in Mass Spectrometry,<br />
July, p. 10.<br />
Evans, Megan. Salary Survey: Salaries<br />
and Stress on the Rise. March, p. 32.<br />
F<br />
Fadgen, Keith. See Stapels, Martha.<br />
Farley, Vincent. See Chamberland,<br />
Martin.<br />
Fernandez-Lima, Francisco A. See<br />
Becker, Christopher.<br />
Feustel, Manfred, and Briggs, Jenni.<br />
Rapid Analysis of Inks on Paper by<br />
Viewing FT-IR–ATR <strong>Spectroscopy</strong>.<br />
FT-IR Technology for Today’s Spectroscopists,<br />
August, p. 16.<br />
Fischer, H. See Schmidt, U.<br />
Fu, Xintong. See Yu, Kate.<br />
G<br />
Gabriele, Peter D. See Reffner, John<br />
A.<br />
Garner, Mark M. See Ghobarah, Hesham.<br />
Gayraud, Nicolas; Kornaszewski, Lukasz;<br />
Stone, James M.; Knight, Jonathan<br />
C.; Reid, Derryck T.; MacPherson,<br />
William N.; and Hand, Duncan<br />
P. Mid-Infrared Gas Sensing Using<br />
a Photonic Bandgap Fiber as a Gas<br />
Cell. January, p. 46.
www.spectroscopyonline.com<br />
December 2009 <strong>Spectroscopy</strong> 24(12) 75<br />
Gebler, John C. See Chakraborty, Asish<br />
B.<br />
Gelsinger-Austin, Paul. “Advantages<br />
of High OD Filters to Microscopy,”<br />
in Laser and Optics Interface. July,<br />
p. 24.<br />
Ghobarah, Hesham; Jones, Elliott B.;<br />
and Garner, Mark M. Metabolite<br />
Profiling Applications in Early Drug<br />
Discovery. Current Trends in Mass<br />
Spectrometry, October, p. 44.<br />
Ghosh, Dipankar. See Kellman,<br />
Markus.<br />
Gong, Hang. See Cai, Changqun.<br />
Gottfried, Jennifer L. See De Lucia Jr.,<br />
Frank C.<br />
Guo, Hongzhu. See Yu, Kate.<br />
H<br />
Hahn, David W. Laser-Induced Breakdown<br />
<strong>Spectroscopy</strong> for Analysis of<br />
Aerosol Particles: The Path Toward<br />
Quantitative Analysis. September, p.<br />
26.<br />
Hail, M. See Scott, G.<br />
Hamester, Meike; McSheehy, Shona;<br />
and Rodushkin, Ilia. Magnet or Cell?<br />
A Comparison of High-Resolution<br />
Sector Field ICP-MS and Collision–<br />
Reaction Cell Quadrupole ICP-MS.<br />
Current Trends in Mass Spectrometry,<br />
October, p. 26.<br />
Hand, Duncan P. See Gayraud, Nicolas.<br />
Hanold, Karl A. See Syage, Jack A.<br />
Heim, John, and Pugh, Scott. Nonderivatized<br />
Drug-Screen Analysis in<br />
Urine with Automated Solid Phase<br />
Microextraction and Comprehensive<br />
Two-Dimensional GC–TOF-MS.<br />
Current Trends in Mass Spectrometry,<br />
March, p. 26.<br />
Hobbs, Steve. See Neyer, David.<br />
Hodkiewicz, Joe and Wall, Mark.<br />
Raman <strong>Spectroscopy</strong> as a Rapid<br />
Characterization Tool for Heterogeneous<br />
Solids. Raman Technology for<br />
Today’s Spectroscopists, June, p. 18.<br />
Hollricher, O. See Schmidt, U.<br />
Huhmer, Andreas. Successfully Identifying<br />
Proteins and Their Modifications<br />
Using Electron Transfer Dissociation<br />
Linear Ion Trap Mass Spectrometry.<br />
Current Trends in Mass Spectrometry,<br />
March, p. 22.<br />
I<br />
Ibach, W. See Schmidt, U.<br />
Impey, Gary. See Simons, Brigitte.<br />
J<br />
Jasinevicius, Renata. See Lowry,<br />
Steve.<br />
Jones, Elliott B. See Ghobarah, Hesham.<br />
Jones, Patrick R. See Sparkman, O.<br />
David.<br />
K<br />
Kansal, Monika. See Sanchez, A.<br />
Carl.<br />
Kellman, Markus; Wieghaus, Andreas;<br />
Muenster, Helmut; Taylor, Lester;<br />
and Ghosh, Dipankar. Using High-<br />
Resolution LC–MS to Analyze Complex<br />
Sample. Current Trends in Mass<br />
Spectrometry, May, p. 38.<br />
Knight, Jonathan C. See Gayraud,<br />
Nicolas.<br />
Kornaszewski, Lukasz. See Gayraud,<br />
Nicolas.<br />
Koshoubu, Jun. See Larsen, Richard<br />
A.<br />
Krastins, Bryan. See Sarracino,<br />
David.<br />
L<br />
Lagueux, Philippe. See Chamberland,<br />
Martin.<br />
Lamontagne, Marc. See Botonjic-Sehic,<br />
Edita.<br />
Larsen, Richard A.; Akao, Ken-ichi;<br />
Sugiyama, Hiroshi; and Koshoubu,<br />
Jun. Advanced Infrared Imaging for<br />
Sample Analysis. FT-IR Technology<br />
for Today’s Spectroscopists, August,<br />
p. 42.<br />
Later, Douglas W.; Wirth, Tiffany C.;<br />
Bowerbank, Christopher R.; Lee,<br />
Edgar D.; and Sadowski, Charles S.<br />
Rapid Field Detection of Chemical<br />
Warfare Agents and Toxic Industrial<br />
Chemicals Using a Hand-Portable<br />
GC–TMS System. Homeland Security,<br />
April, p. 6.<br />
Latiff, Aishah, and Churley, Melissa.<br />
The Role of Triple Quadrupole<br />
GC–MS in Steroid Analysis. Current<br />
Trends in Mass Spectrometry, May, p.<br />
33.<br />
Leary, Pauline E. See Reffner, John A.<br />
Lee, Edgar D. See Later, Douglas W.<br />
Lee, Eunah. See Adar, Fran.<br />
Leroy, Emmanuel. See Whitley, Andrew.<br />
Lesaicherre, Marie; Paxon, Tracy L.;<br />
Burrell, Michael C.; Sunderland,<br />
William Scott; Linsebigler, Amy;<br />
and Mondello, Frank J. Dual-Use<br />
Raman <strong>Spectroscopy</strong> for Chemical<br />
and Biological Agent Identification.<br />
Raman Technology for Today’s Spectroscopists,<br />
June, p. 6.<br />
Lin, Dayin. See Miller, Christine.<br />
Linsebigler, Amy. See Lesaicherre,<br />
Marie.<br />
Liu, Chunyi. See Bol´shakov, Alexander.<br />
Lopez, Mary F. See Sarracino, David.<br />
Lowry, Steve; Boyle, Ross; and Bradley,<br />
Mike. Analysis of Solar Silicon Using<br />
High-Throughput <strong>Spectroscopy</strong>.
76 <strong>Spectroscopy</strong> 24(12) December 2009 www.spectroscopyonline.com<br />
FT-IR Technology for Today’s Spectroscopists,<br />
August, p. 28.<br />
Lowry, Steve; Wieboldt, Dick; Dalrymple,<br />
Dave; Jasinevicius, Renata;<br />
and Downs, Robert T. The Use of a<br />
Raman Spectral Database of Minerals<br />
for the Rapid Verification of Semiprecious<br />
Gemstones. May, p. 52.<br />
M<br />
Macho, Jorge. Low-Resolution Raman<br />
<strong>Spectroscopy</strong>, the Photonic Engine<br />
Behind Materials Identification’s<br />
Promising Future. Raman Technology<br />
for Today’s Spectroscopists, June,<br />
p. 46.<br />
MacPherson, William N. See Gayraud,<br />
Nicolas.<br />
Magarini, Riccardo. ICP-MS Determination<br />
of Micro and Macro Elements<br />
in Waters. Application of ICP & ICP-<br />
MS Techniques for Today’s Spectroscopist,<br />
November, p. 45.<br />
Mahar, Maura; Almeida, Manuel; and<br />
Brown, Peter. Determination of<br />
Toxic Elements Leached from Toys<br />
and Household Structures by Inductively<br />
Coupled Plasma–Optical Emission<br />
<strong>Spectroscopy</strong>. Application of ICP<br />
& ICP-MS Techniques for Today’s<br />
Spectroscopist, November, p. 24.<br />
Mark, Howard. Pittcon New Product<br />
Review. May, p. 22.<br />
Mark, Howard, and Workman Jr.,<br />
Jerome. “The Long, Complicated,<br />
Tedious, and Difficult Route to<br />
Principal Components: Coda,” in<br />
Chemometrics in <strong>Spectroscopy</strong>. May,<br />
p. 14.<br />
Mark, Howard, and Workman Jr.,<br />
Jerome. “The Long, Complicated,<br />
Tedious and Difficult Route to Principal<br />
Components: Part VI,” in Chemometrics<br />
in <strong>Spectroscopy</strong>. February,<br />
p. 16.<br />
McCurdy, Ed. Comparing Collision–<br />
Reaction Cell Modes for the Measurement<br />
of Interfered Analytes in<br />
Complex Matrices. Current Trends in<br />
Mass Spectrometry, October, p. 30.<br />
McDowall, R.D. “Are You Getting Value<br />
from Your Spectrometer?” in Focus<br />
on Quality. December, p. 67.<br />
McDowall, R.D. “The Tiger Has Sharp<br />
New Teeth,” in Focus on Quality. November,<br />
p. 23.<br />
McDowall, R.D. “Understanding and<br />
Interpreting the New GAMP 5 Software<br />
Categories,” in Focus on Quality.<br />
June, p. 22.<br />
McDowall, R.D. “USP on Analytical<br />
Instrument Qualification and<br />
the Laboratory Impact,” in Focus on<br />
Quality. April, p. 20.<br />
McGinley, M. See Scott, G.<br />
McGinley, Michael. See Scott, Greg.<br />
McSheehy, Shona. Using GC–ICP-MS<br />
for Speciation of Sulfur in Reformulated<br />
Fuels. Application of ICP & ICP-<br />
MS Techniques for Today’s Spectroscopist,<br />
November, p. 40.<br />
McSheehy, Shona. See Hamester,<br />
Meike.<br />
McSheehy, Shona, and Sperling, Michael.<br />
“Hyphenated ICP-MS Techniques<br />
for Speciation Analysis,” in<br />
Atomic Perspectives. March, p. 14.<br />
Menard, Kevin P., and Spragg, Richard.<br />
Combining Raman <strong>Spectroscopy</strong> and<br />
Differential Scanning Calorimetry.<br />
Raman Technology for Today’s Spectroscopists,<br />
June, p. 39.<br />
Miller, Christine, and Lin, Dayin.<br />
Microfluidic Chip-Based Technology<br />
as a Growing Trend in LC–MS<br />
Analysis. Current Trends in Mass<br />
Spectrometry, March, p. 8.<br />
Miziolek, Andrzej. See De Lucia Jr.,<br />
Frank C.<br />
Mondello, Frank J. See Lesaicherre,<br />
Marie.<br />
Morris, Rob. “How Will Distributed<br />
Sensing Inspire Changes in Optical-<br />
Sensing R&D?” in Laser and Optics<br />
Interface. January, p. 40.<br />
Muenster, Helmut. See Kellman,<br />
Markus.<br />
Munson, Chase A. See De Lucia Jr.,<br />
Frank C.<br />
Murphy, Brian. See Yu, Kate.<br />
Murphy, Terry; Roberts, Gareth; and<br />
Davies, Gavin. Chemical Warfare<br />
Agents and Use of Thermal Desorption–GC–MS<br />
to Achieve Improved<br />
Trace-Level Detection. Homeland<br />
Security, April, p. 29.<br />
N<br />
Neubauer, Kenneth. “Advantages and<br />
Disadvantages of Different Column<br />
Types for Speciation Analysis by<br />
LC–ICP-MS,” in Atomic Perspectives.<br />
November, p. 30.<br />
Neufeld, Lawrence. Cone Care and<br />
Maintenance. Application of ICP &<br />
ICP-MS Techniques for Today’s Spectroscopist,<br />
November, p. 32.<br />
Newbury, Dale E. The Revolution in<br />
Energy Dispersive X-Ray Spectrometry:<br />
Spectrum Imaging at Output<br />
Count Rates Above 1 MHz with the<br />
Silicon Drift Detector on a Scanning<br />
Electron Microscope. July, p. 32.<br />
Neyer, David, and Hobbs, Steve. Application<br />
of Microbore UHPLC–MS-<br />
MS to the Quantitation of In Vivo<br />
Pharmacokinetic Study Samples.<br />
Current Trends in Mass Spectrometry,<br />
July, p. 40.<br />
Nielsen, Claus Hélix. See Petersen,<br />
Frederic N. R.<br />
P<br />
Paxon, Tracy L. See Lesaicherre,<br />
Marie.<br />
Petersen, Frederic N.R.; and Nielsen,<br />
Claus Hélix. Raman <strong>Spectroscopy</strong> as<br />
a Tool for Investigating Lipid–Protein<br />
Interactions. October, p. 26.<br />
Prakash, Amol. See Sarracino, David.<br />
Pugh, Scott. See Heim, John.<br />
R<br />
Reffner, John A.; Gabriele, Peter D.;<br />
and Leary, Pauline E. Detection<br />
and Sourcing of Counterfeit Pharmaceutical<br />
Products and Consumer<br />
Goods. FT-IR Technology for Today’s<br />
Spectroscopists, August, p. 10.<br />
Reid, Derryck T. See Gayraud, Nicolas.<br />
Rivera, B. See Scott, G.
www.spectroscopyonline.com<br />
December 2009 <strong>Spectroscopy</strong> 24(12) 77<br />
Roberts, Gareth. See Murphy, Terry.<br />
Rodushkin, Ilia. See Hamester,<br />
Meike.<br />
Russell, David H. See Becker, Christopher.<br />
Russo, Richard. See Bol´shakov,<br />
Alexander.<br />
S<br />
Sadowski, Charles S. See Later,<br />
Douglas W.<br />
Sanchez, A. Carl, and Kansal, Monika.<br />
Structured Approach to Method Development<br />
for Bioanalytical HILIC–<br />
MS-MS Applications. Current Trends<br />
in Mass Spectrometry, May, p. 44.<br />
Sarracino, David; Krastins, Bryan;<br />
Prakash, Amol; Lopez, Mary F.;<br />
Wong, Waichi; Zorn, Emmanuel;<br />
and Athanas, Michael. Quantitative<br />
Proteomic Workflow for Discovery<br />
of Early Rejection Kidney Transplant<br />
Peptide Biomarkers and Subsequent<br />
Development of SRM Assays in<br />
Urine. Current Trends in Mass Spectrometry,<br />
July, p. 34.<br />
Schmid, Lawrence S. <strong>Spectroscopy</strong>:<br />
Enduring During Uncertain Times.<br />
March, p. 38.<br />
Schmidt, U.; Ibach, W.; Fischer, H.; and<br />
Hollricher, O. Analysis of Multicomponent<br />
Polymer Blends with Confocal<br />
Raman Imaging and Atomic<br />
Force Microscopy. Raman Technology<br />
for Today’s Spectroscopists, June,<br />
p. 32.<br />
Schreiber, André, and von Czaplewski,<br />
Kristin. Recent Trends in the Use of<br />
LC–MS-MS for the Testing of Food<br />
and Environmental Contaminants.<br />
Current Trends in Mass Spectrometry,<br />
March, p. 16.<br />
Scott, G.; Hail, M.; Rivera, B.; and Mc-<br />
Ginley, M. ADME/Pharmacokinetic<br />
Studies from Serum and Plasma: Improvements<br />
in Sample Preparation<br />
and LC–MS Analysis of Therapeutic<br />
Oligonucleotides. Current Trends in<br />
Mass Spectrometry, July, p. 44.<br />
Scott, Greg; Champion, Matthew;<br />
and McGinley, Michael. Improving<br />
Oligonucleotide Sensitivity and<br />
Separation for LC–MS Applications.<br />
Current Trends in Mass Spectrometry,<br />
March, p. 30.<br />
Shockcor, John. See Yu, Kate.<br />
Simons, Brigitte; Impey, Gary; and<br />
Duchoslav, Eva. Accelerated Discovery<br />
and Quantitation of Lipids in<br />
Complex Extracts. Current Trends in<br />
Mass Spectrometry, May, p. 12.<br />
Skilton, St John. See Chakraborty,<br />
Asish B.<br />
Sparkman, O. David; Jones, Patrick R.;<br />
and Curtis, Matthew. Anatomy of an<br />
Ion’s Fragmentation After Electron<br />
Ionization, Part I. Current Trends in<br />
Mass Spectrometry, May, p. 18.<br />
Sparkman, O. David; Jones, Patrick R.;<br />
and Curtis, Matthew. Anatomy of an<br />
Ion’s Fragmentation After Electron<br />
Ionization, Part II. Current Trends in<br />
Mass Spectrometry, July, p. 12.<br />
Sperling, Michael. See McSheehy,<br />
Shona.<br />
Spragg, Richard. See Menard, Kevin<br />
P.<br />
Stapels, Martha, and Fadgen, Keith.<br />
A Reproducible Online 2D Reversed<br />
Phase–Reversed Phase High–Low pH<br />
Method for Qualitative and Quantitative<br />
Proteomics. Current Trends in<br />
Mass Spectrometry, March, p. 14.<br />
Stone, James M. See Gay raud,<br />
Nicolas.<br />
Sugiyama, Hiroshi. See Larsen, Richard<br />
A.<br />
Sunderland, William Scott. See Lesaicherre,<br />
Marie.<br />
Sword, Duane. Portable FT-IR and<br />
Raman <strong>Spectroscopy</strong> for Explosives<br />
Identification. Homeland Security,<br />
April, p. 16.<br />
Syage, Jack A., and Hanold, Karl A.<br />
Combating Terrorism with Mass<br />
Spectrometry — Screening People for<br />
Explosives. Current Trends in Mass<br />
Spectrometry, July, p. 26.<br />
T<br />
Taday, Philip F. “Terahertz Pulsed Imaging<br />
for Nondestructive Testing of<br />
Pharmaceutical Products,” in Lasers<br />
and Optics Interface. April, p. 28.<br />
Takeuchi, Seiji. Polarization Measurement<br />
of Film Using Single-Reflection<br />
FT-IR–ATR. FT-IR Technology<br />
for Today’s Spectroscopists, August,<br />
p. 22.<br />
Taylor, Lester. See Kellman, Markus.<br />
Thompson, Laura. “Software Features
78 <strong>Spectroscopy</strong> 24(12) December 2009 www.spectroscopyonline.com<br />
Jose; Fu, Xintong; Chen, Yougen;<br />
Guo, Hongzhu; Shockcor, John; and<br />
Murphy, Brian. Using LC–oa-TOF<br />
MS E with a Multivariate Statistical<br />
Sample Profiling Strategy to Distinguish<br />
Chinese Red Ginseng from Korean<br />
Red Ginseng. Current Trends in<br />
Mass Spectrometry, October, p. 36.<br />
Yuki, Hashi. See Yin, Liangliang.<br />
Z<br />
Zhang, Changjiang. See Cheng, Cungui.<br />
Zorn, Emmanuel. See Sarracino,<br />
David.<br />
SUBJECTS<br />
to Improve Quality Control and Data<br />
Validation in the Inorganic Laboratory,”<br />
in Atomic Perspectives. July,<br />
p. 20.<br />
Tian, Yumei. See Cheng, Cungui.<br />
Tsaparikos, Mary. See Botonjic-Sehic,<br />
Edita.<br />
V<br />
Villemaire, André. See Chamberland,<br />
Martin.<br />
Volmer, Dietrich A. See Bluck, Les.<br />
von Czaplewski, Kristin. See Schreiber,<br />
André.<br />
W<br />
Wall, Mark. See Hodkiewicz, Joe.<br />
Weng, Chao; Chen, Xiaoming; and<br />
Cai, Changqun. Spectral Studies on<br />
the Interaction of [Ru(bpy) 2<br />
(BTIP)] 2+<br />
with DNA and Determination of<br />
Nucleic Acids at Nanogram Levels.<br />
June, p. 39.<br />
Whitley, Andrew; Leroy, Emmanuel;<br />
and Adar, Fran. FT-IR–Raman<br />
Combination: The Perfect Analytical<br />
Solution for Vibrational Spectroscopists.<br />
FT-IR Technology for Today’s<br />
Spectroscopists, August, p. 35.<br />
Whitley, Andrew. See Adar, Fran.<br />
Wieboldt, Dick. See Lowry, Steve.<br />
Wieghaus, Andreas. See Kellman,<br />
Markus.<br />
Wilbur, Steven M. Factors Determining<br />
Sensitivity in ICP-MS. Application of<br />
ICP & ICP-MS Techniques for Today’s<br />
Spectroscopist, November, p. 10.<br />
Wilbur, Steven. “Universal Quantification<br />
— The Uncelebrated Strength<br />
of ICP-MS,” in Atomic Perspectives.<br />
May, p. 16.<br />
Wirth, Tiffany C. See Later, Douglas<br />
W.<br />
Wong, Waichi. See Sarracino, David.<br />
Workman Jr., Jerome. See Mark, Howard.<br />
Workman Jr., Jerome, and Mark, Howard.<br />
“Statistics and Chemometrics<br />
for Clinical Data Reporting, Part I,”<br />
in Chemometrics in <strong>Spectroscopy</strong>.<br />
June, p. 18.<br />
Workman Jr., Jerome, and Mark, Howard.<br />
“Statistics and Chemometrics<br />
for Clinical Data Reporting, Part II:<br />
Using Excel for Computations,” in<br />
Chemometrics in <strong>Spectroscopy</strong>. October,<br />
p. 20.<br />
X<br />
Xie, Hongwei. See Chakraborty, Asish<br />
B.<br />
Xin, Mintong. See Yu, Kate.<br />
Xiong, Wei. See Cheng, Cungui.<br />
Y<br />
Yin, Liangliang; Dong, Jing; Yuki,<br />
Hashi; and Chen, Shizhong. Online<br />
Identification of Flavones from Flos<br />
Chrysanthemi by LC–MS-IT-TOF.<br />
Current Trends in Mass Spectrometry,<br />
October, p. 22.<br />
Yoo, Jong H. See Bol´shakov, Alexander.<br />
Yu, Kate; Xin, Mintong; Castro-Perez,<br />
ATOMIC PERSPECTIVES COLUMN<br />
“Advantages and Disadvantages of Different<br />
Column Types for Speciation<br />
Analysis by LC–ICP-MS,” in Atomic<br />
Perspectives. Kenneth Neubauer. November,<br />
p. 30.<br />
“Hyphenated ICP-MS Techniques for<br />
Speciation Analysis,” in Atomic Perspectives.<br />
Shona McSheehy and Michael<br />
Sperling. March, p. 14.<br />
“Software Features to Improve Quality<br />
Control and Data Validation in the<br />
Inorganic Laboratory,” in Atomic<br />
Perspectives. Laura Thompson. July,<br />
p. 20.<br />
“Universal Quantification — The Uncelebrated<br />
Strength of ICP-MS,” in<br />
Atomic Perspectives. Steven Wilbur.<br />
May, p. 16.<br />
ATOMIC SPECTROSCOPY<br />
“Advantages and Disadvantages of Different<br />
Column Types for Speciation<br />
Analysis by LC–ICP-MS,” in Atomic<br />
Perspectives. Kenneth Neubauer. November,<br />
p. 30.<br />
“Higher Resolution Mass Analysis in<br />
Inductively Coupled Plasma–Mass<br />
Spectrometry,” in Mass Spectrometry<br />
Forum. Kenneth L. Busch. January,<br />
p. 30.<br />
“Hyphenated ICP-MS Techniques for<br />
Speciation Analysis,” in Atomic Perspectives.<br />
Shona McSheehy and Michael<br />
Sperling. March, p. 14.<br />
“Software Features to Improve Quality<br />
Control and Data Validation in the<br />
Inorganic Laboratory,” in Atomic<br />
Perspectives. Laura Thompson. July,
www.spectroscopyonline.com<br />
December 2009 <strong>Spectroscopy</strong> 24(12) 79<br />
p. 20.<br />
“Universal Quantification — The Uncelebrated<br />
Strength of ICP-MS,” in<br />
Atomic Perspectives. Steven Wilbur.<br />
May, p. 16.<br />
BASELINE COLUMN<br />
“Auger <strong>Spectroscopy</strong>,” in The Baseline.<br />
David W. Ball. June, p. 14.<br />
“Color,” in The Baseline. David W. Ball.<br />
September, p. 16.<br />
“Group Theory and Symmetry, Part I:<br />
Symmetry Elements,” in The Baseline.<br />
David Ball. December, p. 63.<br />
“The Seven Base Units, Part I,” in The<br />
Baseline. David W. Ball. January, p.<br />
22.<br />
“The Seven Base Units, Part II,” in The<br />
Baseline. David W. Ball. April, p. 14.<br />
BIOLOGICAL AND MEDICAL<br />
ANALYSIS<br />
Interaction of Indigo Carmine with<br />
Nucleic Acids in the Presence of Cetyltrimethylammonium<br />
Bromide:<br />
Spectral Studies and the Confirmation<br />
of Combined Points. Changqun<br />
Cai, Xiaoming Chen, and Hang Gong.<br />
November, p. 34.<br />
“Raman <strong>Spectroscopy</strong> for Biomedical<br />
Applications,” in Molecular <strong>Spectroscopy</strong><br />
Workbench. Fran Adar. March,<br />
p. 26.<br />
Raman <strong>Spectroscopy</strong> as a Tool for Investigating<br />
Lipid–Protein Interactions.<br />
Frederic N.R. Petersen and Claus<br />
Hélix Nielsen. October, p. 26.<br />
Spectral Studies on the Interaction of<br />
[Ru(bpy) 2<br />
(BTIP)] 2+ with DNA and<br />
Determination of Nucleic Acids<br />
at Nanogram Levels. Chao Weng,<br />
Xiaoming Chen, and Changqun Cai.<br />
June, p. 39.<br />
CHEMOMETRICS IN<br />
SPECTROSCOPY COLUMN<br />
“The Long, Complicated, Tedious, and<br />
Difficult Route to Principal Components:<br />
Coda,” in Chemometrics<br />
in <strong>Spectroscopy</strong>. Howard Mark and<br />
Jerome Workman Jr. May, p. 14.<br />
“The Long, Complicated, Tedious and<br />
Difficult Route to Principal Components:<br />
Part VI,” in Chemometrics in<br />
<strong>Spectroscopy</strong>. Howard Mark and Jerome<br />
Workman Jr. February, p. 16.<br />
“Statistics and Chemometrics for<br />
Clinical Data Reporting, Part I,”<br />
in Chemometrics in <strong>Spectroscopy</strong>.<br />
Jerome Workman Jr. and Howard<br />
Mark. June, p. 18.<br />
“Statistics and Chemometrics for Clinical<br />
Data Reporting, Part II: Using Excel<br />
for Computations,” in Chemometrics<br />
in <strong>Spectroscopy</strong>. Jerome Workman Jr.<br />
and Howard Mark. October, p. 20.<br />
FIBER OPTICS<br />
Mid-Infrared Gas Sensing Using a Photonic<br />
Bandgap Fiber as a Gas Cell.<br />
Nicolas Gayraud, Lukasz Kornaszewski,<br />
James M. Stone, Jonathan C.<br />
Knight, Derryck T. Reid, William N.<br />
MacPherson, and Duncan P. Hand.<br />
January, p. 46.<br />
FOCUS ON QUALITY COLUMN<br />
“Are You Getting Value from Your<br />
Spectrometer?” in Focus on Quality.<br />
R.D. McDowall. December, p. 67.<br />
“The Tiger Has Sharp New Teeth,” in<br />
Focus on Quality. R.D. McDowall.<br />
November, p. 23.<br />
“Understanding and Interpreting the<br />
New GAMP 5 Software Categories,”<br />
in Focus on Quality. R.D. McDowall.<br />
June, p. 22.<br />
“USP on Analytical Instrument<br />
Qualification and the Laboratory<br />
Impact,” in Focus on Quality. R.D.<br />
McDowall. April, p. 20.<br />
FORENSIC APPLICATIONS<br />
Forensic Application of Near-Infrared<br />
<strong>Spectroscopy</strong>: Aging of Bloodstains.<br />
Edita Botonjic-Sehic, Chris W. Brown,<br />
Marc Lamontagne, and Mary Tsaparikos.<br />
February, p. 42.<br />
FT-IR SPECTROSCOPY<br />
“FT-IR and Raman: A Synergism, Not<br />
Competing Technologies,” in Molecular<br />
<strong>Spectroscopy</strong> Workbench. Fran<br />
Adar. October, p. 16.<br />
A Novel Recognition of Three Kinds of<br />
Sibling Plants Using FT-IR with Continuous<br />
Wavelet Feature Extraction<br />
Combined with an Artificial Neural<br />
Network. Cungui Cheng, Wei Xiong,<br />
Yumei Tian, and Changjiang Zhang.<br />
February, p. 58.<br />
FUELS<br />
Ion Mobility-Mass Spectrometry: A Tool<br />
for Characterizing the Petroleome.<br />
Christopher Becker, Francisco A.<br />
Fernandez-Lima, and David H. Russell.<br />
April, p. 38.<br />
ICP AND ICP-MS<br />
“Advantages and Disadvantages of Different<br />
Column Types for Speciation<br />
Analysis by LC–ICP-MS,” in Atomic<br />
Perspectives. Kenneth Neubauer. November,<br />
p. 30.<br />
“Higher Resolution Mass Analysis in<br />
Inductively Coupled Plasma–Mass<br />
Spectrometry,” in Mass Spectrometry<br />
Forum. Kenneth L. Busch. January,<br />
p. 30.<br />
“Hyphenated ICP-MS Techniques for<br />
Speciation Analysis,” in Atomic Perspectives.<br />
Shona McSheehy and Michael<br />
Sperling. March, p. 14.<br />
“Universal Quantification — The Uncelebrated<br />
Strength of ICP-MS,” in<br />
Atomic Perspectives. Steven Wilbur.<br />
May, p. 16.<br />
INFRARED SPECTROSCOPY<br />
Mid-Infrared Gas Sensing Using a Photonic<br />
Bandgap Fiber as a Gas Cell.<br />
Nicolas Gayraud, Lukasz Kornaszewski,<br />
James M. Stone, Jonathan C.<br />
Knight, Derryck T. Reid, William N.<br />
MacPherson, and Duncan P. Hand.<br />
January, p. 46.<br />
LASERS AND OPTICS INTERFACE<br />
COLUMN<br />
“Advantages of High OD Filters to Microscopy,”<br />
in Laser and Optics Interface.<br />
Paul Gelsinger-Austin. July,<br />
p. 24.<br />
“How Will Distributed Sensing Inspire<br />
Changes in Optical-Sensing R&D?”<br />
in Laser and Optics Interface. Rob<br />
Morris. January, p. 40.<br />
“Terahertz Pulsed Imaging for Nondestructive<br />
Testing of Pharmaceutical<br />
Products,” in Lasers and Optics Interface.<br />
Philip F. Taday. April, p. 28.<br />
LASERS<br />
Current Status of Standoff LIBS Security<br />
Applications at the United States<br />
Army Research Laboratory. Frank<br />
C. De Lucia Jr., Jennifer L. Gottfried,<br />
Chase A. Munson, and Andrzej<br />
Miziolek. June, p. 32.<br />
Discrimination of Complex Substances
80 <strong>Spectroscopy</strong> 24(12) December 2009 www.spectroscopyonline.com<br />
with Laser-Induced Breakdown <strong>Spectroscopy</strong>.<br />
Alexander Bol´shakov, Jong<br />
H. Yoo, Chunyi Liu, and Richard<br />
Russo. October, p. 36.<br />
“How Will Distributed Sensing Inspire<br />
Changes in Optical-Sensing R&D?”<br />
in Laser and Optics Interface. Rob<br />
Morris. January, p. 40.<br />
Laser-Induced Breakdown <strong>Spectroscopy</strong><br />
for Analysis of Aerosol Particles: The<br />
Path Toward Quantitative Analysis.<br />
David W. Hahn. September, p. 26.<br />
“Terahertz Pulsed Imaging for Nondestructive<br />
Testing of Pharmaceutical<br />
Products,” in Lasers and Optics Interface.<br />
Philip F. Taday. April, p. 28.<br />
MARKET PROFILE<br />
<strong>Spectroscopy</strong>: Enduring During Uncertain<br />
Times. Lawrence S. Schmid.<br />
March, p. 38.<br />
MASS SPECTROMETRY FORUM<br />
COLUMN<br />
“Development of Mass Spectrometry<br />
in the United States: The First<br />
50 Years,” in Mass Spectrometry<br />
Forum. Kenneth L. Busch. March,<br />
p. 18.<br />
“Higher Resolution Mass Analysis in<br />
Inductively Coupled Plasma–Mass<br />
Spectrometry,” in Mass Spectrometry<br />
Forum. Kenneth L. Busch. January,<br />
p. 30.<br />
“Ion Lenses,” in Mass Spectrometry<br />
Forum. Kenneth L. Busch. September,<br />
p. 20.<br />
“Pressure and Vacuum: Not Really Trivial,”<br />
in Mass Spectrometry Forum.<br />
Kenneth L. Busch. November, p. 16.<br />
“Sampling in Mass Spectrometry,” in<br />
Mass Spectrometry Forum. Kenneth<br />
L. Busch. July, p. 14.<br />
MASS SPECTROMETRY<br />
“Development of Mass Spectrometry<br />
in the United States: The First<br />
50 Years,” in Mass Spectrometry<br />
Forum. Kenneth L. Busch. March,<br />
p. 18.<br />
“Higher Resolution Mass Analysis in<br />
Inductively Coupled Plasma–Mass<br />
Spectrometry,” in Mass Spectrometry<br />
Forum. Kenneth L. Busch. January,<br />
p. 30.<br />
“Ion Lenses,” in Mass Spectrometry<br />
Forum. Kenneth L. Busch.<br />
September, p. 20.<br />
Ion Mobility-Mass Spectrometry: A<br />
Tool for Characterizing the Petroleome.<br />
Christopher Becker, Francisco<br />
A. Fernandez-Lima, and David<br />
H. Russell. April, p. 38.<br />
“Pressure and Vacuum: Not Really<br />
Trivial,” in Mass Spectrometry<br />
Forum. Kenneth L. Busch. November,<br />
p. 16.<br />
The Role of Naturally Occurring Stable<br />
Isotopes in Mass Spectrometry, Part<br />
II: The Instrumentation. Les Bluck<br />
and Dietrich A. Volmer. February,<br />
p. 50.<br />
The Role of Naturally Occurring Stable<br />
Isotopes in Mass Spectrometry,<br />
Part III: Small Gas Molecule Calculations.<br />
Les Bluck and Dietrich A.<br />
Volmer. September, p. 34.<br />
“Sampling in Mass Spectrometry,” in<br />
Mass Spectrometry Forum. Kenneth<br />
L. Busch. July, p. 14.<br />
“Universal Quantification — The Uncelebrated<br />
Strength of ICP-MS,” in<br />
Atomic Perspectives. Steven Wilbur.<br />
May, p. 16.<br />
MOLECULAR SPECTROSCOPY<br />
WORKBENCH COLUMN<br />
“FT-IR and Raman: A Synergism, Not<br />
Competing Technologies,” in Molecular<br />
<strong>Spectroscopy</strong> Workbench.<br />
Fran Adar. October, p. 16.<br />
“Raman <strong>Spectroscopy</strong> for Biomedical<br />
Applications,” in Molecular <strong>Spectroscopy</strong><br />
Workbench. Fran Adar. March,<br />
p. 26.<br />
“Raman <strong>Spectroscopy</strong> of Carbon —<br />
More Information Than You Would<br />
Think,” in Molecular <strong>Spectroscopy</strong><br />
Workbench. Fran Adar. February,<br />
p. 28.<br />
NEAR-IR SPECTROSCOPY<br />
Forensic Application of Near-Infrared<br />
<strong>Spectroscopy</strong>: Aging of Bloodstains.<br />
Edita Botonjic-Sehic, Chris<br />
W. Brown, Marc Lamontagne, and<br />
Mary Tsaparikos. February, p. 42.<br />
NMR SPECTROSCOPY<br />
Interaction of Indigo Carmine with<br />
Nucleic Acids in the Presence of<br />
Cetyltrimethylammonium Bromide:<br />
Spectral Studies and the Confirmation<br />
of Combined Points. Changqun<br />
Cai, Xiaoming Chen, and Hang<br />
Gong. November, p. 34.<br />
OPTICS<br />
“Advantages of High OD Filters to Microscopy,”<br />
in Laser and Optics Interface.<br />
Paul Gelsinger-Austin. July,<br />
p. 24.<br />
“Group Theory and Symmetry, Part I:<br />
Symmetry Elements,” in The Baseline.<br />
David Ball. December, p. 63.<br />
PHARMACEUTICAL<br />
APPLICATIONS<br />
“Are You Getting Value from Your<br />
Spectrometer?” in Focus on Quality.<br />
R.D. McDowall. December, p. 67.<br />
“Terahertz Pulsed Imaging for<br />
Nondestructive Testing of Pharmaceutical<br />
Products,” in Lasers and<br />
Optics Interface. Philip F. Taday.<br />
April, p. 28.<br />
“The Tiger Has Sharp New Teeth,” in<br />
Focus on Quality. R.D. McDowall.<br />
November, p. 23.<br />
“USP on Analytical Instrument<br />
Qualification and the Laboratory<br />
Impact,” in Focus on Quality. R.D.<br />
McDowall. April, p. 20.<br />
PRODUCT REVIEW<br />
Pittcon 2009 New Product Review.<br />
Howard Mark. May, p. 22.
www.spectroscopyonline.com<br />
December 2009 <strong>Spectroscopy</strong> 24(12) 81<br />
RAMAN SPECTROSCOPY<br />
“FT-IR and Raman: A Synergism, Not<br />
Competing Technologies,” in Molecular<br />
<strong>Spectroscopy</strong> Workbench.<br />
Fran Adar. October, p. 16.<br />
“Raman <strong>Spectroscopy</strong> for Biomedical<br />
Applications,” in Molecular <strong>Spectroscopy</strong><br />
Workbench. Fran Adar.<br />
March, p. 26.<br />
“Raman <strong>Spectroscopy</strong> of Carbon —<br />
More Information Than You Would<br />
Think,” in Molecular <strong>Spectroscopy</strong><br />
Workbench. Fran Adar. February,<br />
p. 28.<br />
Raman <strong>Spectroscopy</strong> as a Tool for Investigating<br />
Lipid–Protein Interactions.<br />
Frederic N.R. Petersen and Claus<br />
Hélix Nielsen. October, p. 26.<br />
The Use of a Raman Spectral Database<br />
of Minerals for the Rapid Verification<br />
of Semiprecious Gemstones.<br />
Steve Lowry, Dick Wieboldt, Dave<br />
Dalrymple, Renata Jasinevicius, and<br />
Robert T. Downs. May, p. 52.<br />
REGULATORY ISSUES<br />
“Are You Getting Value from Your Spectrometer?”<br />
in Focus on Quality. R.D.<br />
McDowall. December, p. 67.<br />
“The Tiger Has Sharp New Teeth,” in<br />
Focus on Quality. R.D. McDowall.<br />
November, p. 23.<br />
“Understanding and Interpreting the<br />
New GAMP 5 Software Categories,”<br />
in Focus on Quality. R.D. McDowall.<br />
June, p. 22.<br />
“USP on Analytical Instrument<br />
Qualification and the Laboratory<br />
Impact,” in Focus on Quality. R.D.<br />
McDowall. April, p. 20.<br />
SALARY SURVEY<br />
2009 Salary Survey: Salaries and Stress<br />
on the Rise. Megan Evans. March,<br />
p. 32.<br />
SPECTRAL INTERPRETATION<br />
Spectral Studies on the Interaction of<br />
[Ru(bpy) 2<br />
(BTIP)] 2+ with DNA and<br />
Determination of Nucleic Acids<br />
at Nanogram Levels. Chao Weng,<br />
Xiaoming Chen, and Changqun Cai.<br />
June, p. 39.<br />
The Use of a Raman Spectral Database<br />
of Minerals for the Rapid Verification<br />
of Semiprecious Gemstones.<br />
Steve Lowry, Dick Wieboldt, Dave<br />
Dalrymple, Renata Jasinevicius, and<br />
Robert T. Downs. May, p. 52.<br />
SUPPLEMENT: APPLICATION OF<br />
ICP & ICP-MS TECHNIQUES FOR<br />
TODAY’S SPECTROSCOPIST<br />
Cone Care and Maintenance. Lawrence<br />
Neufeld. November, p. 32.<br />
Determination of Toxic Elements<br />
Leached from Toys and Household<br />
Structures by Inductively Coupled<br />
Plasma–Optical Emission <strong>Spectroscopy</strong>.<br />
Maura Mahar, Manuel<br />
Almeida, and Peter Brown. November,<br />
p. 24.<br />
Factors Determining Sensitivity in ICP-<br />
MS. Steven M. Wilbur. November, p.<br />
10.<br />
ICP-MS Determination of Micro and<br />
Macro Elements in Waters. Riccardo<br />
Magarini. November, p. 45.<br />
Optimizing Productivity for Environmental<br />
Applications of ICP. Jerry<br />
Dulude and Vesna Dolic. November,<br />
p. 16.<br />
Using GC–ICP-MS for Speciation of<br />
Sulfur in Reformulated Fuels. Shona<br />
McSheehy. November, p. 40.<br />
SUPPLEMENT: CURRENT TRENDS<br />
IN MASS SPECTROMETRY<br />
57th ASMS Conference Review. Megan<br />
Evans. July, p. 10.<br />
Accelerated Discovery and Quantitation<br />
of Lipids in Complex Extracts.<br />
Brigitte Simons, Gary Impey, and<br />
Eva Duchoslav. May, p. 12.<br />
ADME/Pharmacokinetic Studies from<br />
Serum and Plasma: Improvements<br />
in Sample Preparation and LC–MS<br />
Analysis of Therapeutic Oligonucleotides.<br />
G. Scott, M. Hail, B. Rivera,<br />
and M. McGinley. July, p. 44.<br />
Anatomy of an Ion’s Fragmentation<br />
After Electron Ionization, Part I. O.<br />
David Sparkman, Patrick R. Jones,<br />
and Matthew Curtis. May, p. 18.<br />
Anatomy of an Ion’s Fragmentation<br />
After Electron Ionization, Part II. O.<br />
David Sparkman, Patrick R. Jones,<br />
and Matthew Curtis. July, p. 12.<br />
Application of Microbore UHPLC–MS-<br />
MS to the Quantitation of In Vivo<br />
Pharmacokinetic Study Samples.<br />
David Neyer and Steve Hobbs. July,<br />
p. 40.<br />
Combating Terrorism with Mass Spectrometry<br />
— Screening People for<br />
Explosives. Jack A. Syage and Karl<br />
A. Hanold. July, p. 26.<br />
Comparing Collision–Reaction Cell<br />
Modes for the Measurement of Interfered<br />
Analytes in Complex Matrices.<br />
Ed McCurdy. October, p. 30.<br />
High Performance Mass Spectrometry<br />
for Small Molecule and Protein Applications.<br />
Darwin Asa. May, p. 30.<br />
Improving the Analytical Workflow for<br />
Protein Biopharmaceutical Characterization<br />
with a Novel LC–MS System<br />
Solution. Asish Chakraborty,<br />
Hongwei Xie, St John Skilton, John<br />
C. Gebler, and Weibin Chen. July,<br />
p. 26.<br />
Improving Oligonucleotide Sensitivity<br />
and Separation for LC–MS Applications.<br />
Greg Scott, Matthew<br />
Champion, and Michael McGinley.<br />
March, p. 30.<br />
Magnet or Cell? A Comparison of<br />
High-Resolution Sector Field ICP-<br />
MS and Collision–Reaction Cell<br />
Quadrupole ICP-MS. Meike Hamester,<br />
Shona McSheehy, and Ilia Rodushkin.<br />
October, p. 26.<br />
A Mass Spectrometry Glossary.<br />
Kenneth L. Busch. October, p. 10.<br />
Metabolite Profiling Applications in<br />
Early Drug Discovery. Hesham Ghobarah,<br />
Elliott B. Jones, and Mark M.
82 <strong>Spectroscopy</strong> 24(12) December 2009 www.spectroscopyonline.com<br />
Garner. October, p. 44.<br />
Microfluidic Chip-Based Technology as<br />
a Growing Trend in LC–MS Analysis.<br />
Christine Miller and Dayin Lin.<br />
March, p 8.<br />
Nonderivatized Drug-Screen Analysis<br />
in Urine with Automated Solid<br />
Phase Microextraction and Comprehensive<br />
Two-Dimensional GC–TOF-<br />
MS. John Heim and Scott Pugh.<br />
March, p. 26.<br />
Online Identification of Flavones from<br />
Flos Chrysanthemi by LC–MS-IT-<br />
TOF. Liangliang Yin, Jing Dong,<br />
Hashi Yuki, and Shizhong Chen.<br />
October, p. 22.<br />
Quantitative Proteomic Workflow for<br />
Discovery of Early Rejection Kidney<br />
Transplant Peptide Biomarkers and<br />
Subsequent Development of SRM<br />
Assays in Urine. David Sarracino,<br />
Bryan Krastins, Amol Prakash,<br />
Mary F. Lopez, Waichi Wong, Emmanuel<br />
Zorn, and Michael Athanas.<br />
July, p. 34.<br />
Recent Trends in the Use of LC–MS-MS<br />
for the Testing of Food and Environmental<br />
Contaminants. André Schreiber<br />
and Kristin von Czaplewski.<br />
March, p. 16.<br />
A Reproducible Online 2D Reversed<br />
Phase–Reversed Phase High–Low<br />
pH Method for Qualitative and<br />
Quantitative Proteomics. Martha<br />
Stapels and Keith Fadgen. March,<br />
p. 14.<br />
The Role of Triple Quadrupole GC–MS<br />
in Steroid Analysis. Aishah Latiff<br />
and Melissa Churley. May, p. 33.<br />
Structured Approach to Method Development<br />
for Bioanalytical HILIC–<br />
MS-MS Applications. A. Carl Sanchez<br />
and Monika Kansal. May, p.<br />
44.<br />
Successfully Identifying Proteins and<br />
Their Modifications Using Electron<br />
Transfer Dissociation Linear Ion<br />
Trap Mass Spectrometry. Andreas<br />
Huhmer. March, p. 22.<br />
Using High-Resolution LC–MS to<br />
Analyze Complex Sample. Markus<br />
Kel lman, Andreas Wieghaus,<br />
Helmut Muenster, Lester Taylor, and<br />
Dipankar Ghosh. May, p. 38.<br />
Using LC–oa-TOF MS E with a Multivariate<br />
Statistical Sample Profiling<br />
Strategy to Distinguish Chinese Red<br />
Ginseng from Korean Red Ginseng.<br />
Kate Yu, Mintong Xin, Jose Castro-<br />
Perez, Xintong Fu, Yougen Chen,<br />
Hongzhu Guo, John Shockcor, and<br />
Brian Murphy. October, p. 36.<br />
SUPPLEMENT: FT-IR<br />
TECHNOLOGY FOR TODAY’S<br />
SPECTROSCOPISTS<br />
Advanced Infrared Imaging for Sample<br />
Analysis. Richard A. Larsen, Kenichi<br />
Akao, Hiroshi Sugiyama, and<br />
Jun Koshoubu. August, p. 42.<br />
Analysis of Solar Silicon Using High-<br />
Throughput <strong>Spectroscopy</strong>. Steve<br />
Lowry, Ross Boyle, and Mike Bradley.<br />
August, p. 28.<br />
Detection and Sourcing of Counterfeit<br />
Pharmaceutical Products and Consumer<br />
Goods. John A. Reffner, Peter<br />
D. Gabriele, and Pauline E. Leary.<br />
August, p. 10.<br />
FT-IR–Raman Combination: The<br />
Perfect Analytical Solution for Vibrational<br />
Spectroscopists. Andrew<br />
Whitley, Emmanuel Leroy, and Fran<br />
Adar. August, p. 35.<br />
Polarization Measurement of Film<br />
Using Single-Reflection FT-IR–ATR.<br />
Seiji Takeuchi. August, p. 22.<br />
Rapid Analysis of Inks on Paper by<br />
Viewing FT-IR–ATR <strong>Spectroscopy</strong>.<br />
Manfred Feustel and Jenni Briggs.<br />
August, p. 16.<br />
SUPPLEMENT: HOMELAND<br />
SECURITY<br />
Chemical Warfare Agent Spectral Imaging<br />
for Real-Time Identification and<br />
Localization. Martin Chamberland,<br />
Vincent Farley, Philippe Lagueux,<br />
and André Villemaire. April, p. 20.<br />
Chemical Warfare Agents and Use of<br />
Thermal Desorption–GC–MS to<br />
Achieve Improved Trace-Level Detection.<br />
Terry Murphy, Gareth Roberts,<br />
and Gavin Davies. April, p. 29.<br />
Portable FT-IR and Raman <strong>Spectroscopy</strong><br />
for Explosives Identification. Duane<br />
Sword. April, p. 16.<br />
Rapid Field Detection of Chemical<br />
Warfare Agents and Toxic Industrial<br />
Chemicals Using a Hand-Portable<br />
GC–TMS System. Douglas W.<br />
Later, Tiffany C. Wirth, Christopher<br />
R. Bowerbank, Edgar D. Lee, and<br />
Charles S. Sadowski. April, p. 6.<br />
SUPPLEMENT: RAMAN<br />
TECHNOLOGY FOR TODAY’S<br />
SPECTROSCOPISTS<br />
Analysis of Multicomponent Polymer<br />
Blends with Confocal Raman Imaging<br />
and Atomic Force Microscopy. U.<br />
Schmidt, W. Ibach, H. Fischer, and O.<br />
Hollricher. June, p. 32.<br />
Combining Raman <strong>Spectroscopy</strong> and<br />
Differential Scanning Calorimetry.<br />
Kevin P. Menard and Richard Spragg.<br />
June, p. 39.<br />
Dual-Use Raman <strong>Spectroscopy</strong> for<br />
Chemical and Biological Agent Identification.<br />
Marie Lesaicherre, Tracy L.<br />
Paxon, Michael C. Burrell, William<br />
Scott Sunderland, Amy Linsebigler,<br />
and Frank J. Mondello. June, p. 6.<br />
Low-Resolution Raman <strong>Spectroscopy</strong>,<br />
the Photonic Engine Behind Materials<br />
Identification’s Promising Future.<br />
Jorge Macho. June, p. 46.<br />
Raman <strong>Spectroscopy</strong> as a Rapid Characterization<br />
Tool for Heterogeneous<br />
Solids. Joe Hodkiewicz and Mark<br />
Wall. June, p. 18.<br />
Transmission Raman Offers Improved<br />
Quantitation of Pharmaceutical Solids.<br />
Fran Adar, Eunah Lee, and Andrew<br />
Whitley. June, p. 26.<br />
UV SPECTROSCOPY<br />
Interaction of Indigo Carmine with Nucleic<br />
Acids in the Presence of Cetyltrimethylammonium<br />
Bromide: Spectral<br />
Studies and the Confirmation of<br />
Combined Points. Changqun Cai,<br />
Xiaoming Chen, and Hang Gong.<br />
November, p. 34.<br />
Spectral Studies on the Interaction of<br />
[Ru(bpy) 2<br />
(BTIP)] 2+ with DNA and<br />
Determination of Nucleic Acids<br />
at Nanogram Levels. Chao Weng,<br />
Xiaoming Chen, and Changqun Cai.<br />
June, p. 39.<br />
X-RAY SPECTROSCOPY<br />
The Revolution in Energy Dispersive X-<br />
Ray Spectrometry: Spectrum Imaging<br />
at Output Count Rates Above 1<br />
MHz with the Silicon Drift Detector<br />
on a Scanning Electron Microscope.<br />
Dale E. Newbury. July, p. 32. ◾
<strong>Spectroscopy</strong><br />
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DATE FOUNDED<br />
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November 2009 Volume 24 Number 11<br />
<strong>Spectroscopy</strong><br />
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Nucleic Acid Analysis<br />
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