Wetenschappelijk jaaroverzicht 2012 - Catharina Ziekenhuis
Wetenschappelijk jaaroverzicht 2012 - Catharina Ziekenhuis
Wetenschappelijk jaaroverzicht 2012 - Catharina Ziekenhuis
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other was noncompliant. None of the 116 relatives died of CPVT during a 6.7-year follow-up<br />
(range, 1.4-20.9 years).<br />
CONCLUSIONS: Relatives carrying an Ryr2 mutation show a marked phenotypic diversity. The<br />
vast majority do not have signs of supraventricular disease manifestations. Mutation<br />
location may be associated with severity of the phenotype. The arrhythmic event rate during<br />
follow-up was low.<br />
Impactfactor: --<br />
Bracke FA<br />
Is acute hemodynamic response a predictor of long-term outcome in cardiac<br />
resynchronization therapy?<br />
Prinzen FW, Houthuizen P*, Bogaard MD, Gelder B van*, Bracke F*, Cramer MJ,<br />
Leenders GE, Meine M<br />
J Am Coll Cardiol. <strong>2012</strong> Mar 27;59(13):1198; author reply 1198-9<br />
Impactfactor: 14.156<br />
Bracke FA<br />
Left ventricular endocardial pacing in cardiac resynchronisation therapy: Moving<br />
from bench to bedside<br />
Bracke FA*, Gelder BM van*, Dekker LR*, Houthuizen P*, Woorst JF ter*, Teijink JA*<br />
Neth Heart J. <strong>2012</strong> Mar;20(3):118-24. Epub 2011 Nov 9<br />
In cardiac resynchronisation therapy, failure to implant a left ventricular lead in a coronary<br />
sinus branch has been reported in up to 10% of cases. Although surgical insertion of<br />
epicardial leads is considered the standard alternative, this is not without morbidity and<br />
technical limitations. Endocardial left ventricular pacing can be an alternative as it has been<br />
associated with a favourable acute haemodynamic response compared with epicardial<br />
pacing in both animal and human studies. In this paper, we discuss left ventricular<br />
endocardial pacing and compare it with epicardial surgical implantation. Ease of application<br />
and procedural complications and morbidity compare favourably with epicardial surgical<br />
techniques. However, with limited experience, the most important concern is the still<br />
unknown long-term risk of thromboembolic complications. Therefore, for now endovascular<br />
implants should remain reserved for severely symptomatic heart failure patients and<br />
patients at high surgical risk of failed coronary sinus implantation.<br />
Impactfactor: 1.438<br />
Bracke FA<br />
Letter by van Gelder and Bracke Regarding Article, "Left Ventricular Versus<br />
Simultaneous Biventricular Pacing in Patients With Heart Failure and a QRS Complex<br />
>120 Milliseconds"<br />
Gelder BM van*, Bracke FA*<br />
Circulation. <strong>2012</strong> Oct 9;126(15):e238<br />
Impactfactor: 14.739<br />
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