Clinical Approach to Acid-base Disorders - University at Buffalo

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Rules of Acid-Base Problem Interpretation 1. Check for internal consistency 2. Examine the pH 3. Determine if the primary problem is metabolic or respiratory 4. Calculate the anion gap 5. Is it a simple or a mixed disturbance? 6. Determine the underlying clinical problem
Rule #1: Check for Internal Consistency • The pH and P a CO 2 is measured from an arterial blood gas (ABG) sample and the [HCO 3 ] - is then calculated using the Henderson-Hasselbach equation. • Serum measured [HCO 3 ] - should be within 2 mmol/L of the calculated [HCO -. 3 ]
Page 1 and 2: Clinical Approach to Acid-base Diso
Page 3 and 4: Acid-Base Disorders • Metabolic D
Page 5: Maintenance of Acid-Base Balance
Page 9 and 10: Rule #2: Examine the pH • A reduc
Page 11 and 12: Rule #4:Calculate the anion gap •
Page 13 and 14: Mixed Disturbance • Acidosis •
Page 15 and 16: Mixed Disturbance (contd) • Alkal
Page 17 and 18: Expected Compensatory Responses •
Page 19 and 20: Metabolic Acidosis 2. High AG acido
Page 21 and 22: Metabolic Alkalosis 1. Chloride sen
Page 23: Respiratory Alkalosis 1.Problem cau

Clinical Approach to Acid-base Disorders - University at Buffalo

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