Clinical Approach to Acid-base Disorders - University at Buffalo
Clinical Approach to Acid-base Disorders - University at Buffalo
Clinical Approach to Acid-base Disorders - University at Buffalo
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Maintenance of <strong>Acid</strong>-Base<br />
Balance<br />
• Kidneys alter the r<strong>at</strong>e of absorption of [HCO 3 ] - by<br />
increasing its absorption when P a CO 2 increases<br />
(respira<strong>to</strong>ry acidosis) and decreasing the r<strong>at</strong>e of<br />
absorption of [HCO 3 ] - when P a CO 2 decreases<br />
(respira<strong>to</strong>ry alkalosis)<br />
• Lungs compens<strong>at</strong>e for a change in [HCO 3 ] - by<br />
increasing the ventil<strong>at</strong>ion <strong>to</strong> reduce P a CO 2 in<br />
metabolic acidosis and decreasing the ventil<strong>at</strong>ion<br />
<strong>to</strong> reduce P a aCO 2 in metabolic alkalosis.