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Clinical Approach to Acid-base Disorders - University at Buffalo

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Rule #5: Is it a simple or a mixed<br />

disturbance?<br />

• A simple acid-<strong>base</strong> disorder is present if an<br />

expected compensa<strong>to</strong>ry response is seen.<br />

• A mixed d( (acidosis i and alkalosis) l )disorder d is<br />

present if the P a CO 2 or AG is abnormal and the pH<br />

is normal or unchanged, or if the pH is abnormal<br />

and the P a CO 2 is normal or unchanged. These can<br />

be.<br />

– Mixed metabolic and respira<strong>to</strong>ry disorders.<br />

– Mixed metabolic disorders.<br />

– Complex mixed disorders.

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