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(3.2) Cell division is part of the cell cycle. - Durant Road Middle School

(3.2) Cell division is part of the cell cycle. - Durant Road Middle School

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KEY CONCEPT<br />

<strong>Cell</strong> <strong>div<strong>is</strong>ion</strong> <strong>is</strong> <strong>part</strong> <strong>of</strong><br />

<strong>the</strong> <strong>cell</strong> <strong>cycle</strong>.<br />

BEFORE, you learned<br />

• <strong>Cell</strong>s come from o<strong>the</strong>r <strong>cell</strong>s<br />

through <strong>cell</strong> <strong>div<strong>is</strong>ion</strong><br />

•A <strong>cell</strong> must have a full set <strong>of</strong><br />

genetic material to function<br />

• <strong>Cell</strong> <strong>div<strong>is</strong>ion</strong> enables multi<strong>cell</strong>ular<br />

organ<strong>is</strong>ms to develop,<br />

grow, and repair <strong>the</strong>mselves<br />

NOW, you will learn<br />

• About two main stages in <strong>the</strong><br />

<strong>cell</strong> <strong>cycle</strong><br />

• About <strong>the</strong> changes that occur<br />

in <strong>cell</strong>s before mitos<strong>is</strong><br />

• About <strong>the</strong> events that take<br />

place during mitos<strong>is</strong><br />

VOCABULARY<br />

<strong>cell</strong> <strong>cycle</strong> p. 80<br />

interphase p. 81<br />

mitos<strong>is</strong> p. 81<br />

cytokines<strong>is</strong> p. 81<br />

THINK ABOUT<br />

What <strong>is</strong> a <strong>cycle</strong>?<br />

Many things in your everyday life are<br />

<strong>cycle</strong>s. A <strong>cycle</strong> <strong>is</strong> any activity or set <strong>of</strong><br />

events that regularly repeats. Cycles<br />

can be short, like <strong>the</strong> sequence <strong>of</strong> events<br />

that make your heart beat, or <strong>the</strong>y can<br />

be very long, like <strong>the</strong> turning <strong>of</strong> our<br />

galaxy. One example <strong>of</strong> a <strong>cycle</strong> <strong>is</strong> shown<br />

at <strong>the</strong> right. The photographs show a<br />

tree during four seasons in a nor<strong>the</strong>rn<br />

climate. How are <strong>the</strong>se seasons a <strong>cycle</strong>?<br />

RESOURCE CENTER<br />

CLASSZONE.COM<br />

Learn about <strong>the</strong><br />

<strong>cell</strong> <strong>cycle</strong>.<br />

The <strong>cell</strong> <strong>cycle</strong> includes<br />

interphase and <strong>cell</strong> <strong>div<strong>is</strong>ion</strong>.<br />

All living things live, grow, reproduce, and die in a process called a life<br />

<strong>cycle</strong>. The life <strong>cycle</strong> <strong>of</strong> a tree, for example, begins with a seed. Under<br />

<strong>the</strong> right conditions, <strong>the</strong> seed begins to grow. It produces a very small<br />

plant, which may grow over many years into a towering tree. When it<br />

<strong>is</strong> mature, <strong>the</strong> tree makes its own seeds, and <strong>the</strong> <strong>cycle</strong> begins again.<br />

<strong>Cell</strong>s have a life <strong>cycle</strong> too, called <strong>the</strong> <strong>cell</strong> <strong>cycle</strong>. The <strong>cell</strong> <strong>cycle</strong> <strong>is</strong> <strong>the</strong><br />

normal sequence <strong>of</strong> development and <strong>div<strong>is</strong>ion</strong> <strong>of</strong> a <strong>cell</strong>. The <strong>cell</strong> <strong>cycle</strong><br />

cons<strong>is</strong>ts <strong>of</strong> two main phases: one in which <strong>the</strong> <strong>cell</strong> carries out its functions,<br />

called interphase, and one in which <strong>the</strong> <strong>cell</strong> divides, which can<br />

include mitos<strong>is</strong> and cytokines<strong>is</strong>. All <strong>cell</strong>s divide, but only eukaryotes<br />

undergo mitos<strong>is</strong>. Each phase in <strong>the</strong> <strong>cell</strong> <strong>cycle</strong> requires a certain period<br />

<strong>of</strong> time—from hours to days or years, depending on <strong>the</strong> type <strong>of</strong> <strong>cell</strong>.<br />

EA<br />

80 Unit: <strong>Cell</strong>s and Heredity


Interphase<br />

Interphase <strong>is</strong> <strong>the</strong> <strong>part</strong> <strong>of</strong> <strong>the</strong> <strong>cell</strong> <strong>cycle</strong> during which a <strong>cell</strong> <strong>is</strong> not<br />

dividing. Much activity takes place in th<strong>is</strong> phase <strong>of</strong> <strong>the</strong> <strong>cell</strong>’s life.<br />

During interphase, <strong>the</strong> <strong>cell</strong> grows to about twice <strong>the</strong> size it was when<br />

it was first produced. The <strong>cell</strong> also engages in normal life activities,<br />

such as transporting materials in and transporting wastes out. Also,<br />

<strong>cell</strong>ular respiration occurs, which provides <strong>the</strong> energy <strong>the</strong> <strong>cell</strong> needs.<br />

Changes that occur during interphase prepare a <strong>cell</strong> for <strong>div<strong>is</strong>ion</strong>.<br />

Before a <strong>cell</strong> can divide, it duplicates its DNA exactly. Correct copying<br />

<strong>of</strong> <strong>the</strong> DNA <strong>is</strong> very important. It ensures that, after <strong>cell</strong> <strong>div<strong>is</strong>ion</strong>, each<br />

new <strong>cell</strong> gets a complete set <strong>of</strong> DNA. During most <strong>of</strong> interphase, <strong>the</strong><br />

DNA <strong>is</strong> in chromatin form.<br />

VOCABULARY<br />

Make a frame game<br />

diagram for interphase.<br />

Check Your Reading<br />

What <strong>cell</strong> processes occur during interphase?<br />

<strong>Cell</strong> Div<strong>is</strong>ion Phase<br />

Mitos<strong>is</strong> <strong>is</strong> <strong>the</strong> <strong>part</strong> <strong>of</strong> <strong>the</strong> <strong>cell</strong> <strong>cycle</strong> during which <strong>the</strong> nucleus divides.<br />

Prokaryotes do not undergo mitos<strong>is</strong> because <strong>the</strong>y have only one chromosome<br />

and no nucleus. In most <strong>cell</strong>s, mitos<strong>is</strong> <strong>is</strong> <strong>the</strong> shortest period<br />

in <strong>the</strong> life <strong>cycle</strong>. The function <strong>of</strong> mitos<strong>is</strong> <strong>is</strong> to move <strong>the</strong> DNA and<br />

o<strong>the</strong>r material in <strong>the</strong> parent <strong>cell</strong> into position for <strong>cell</strong> <strong>div<strong>is</strong>ion</strong>. When<br />

<strong>the</strong> <strong>cell</strong> divides, each new <strong>cell</strong> gets a full set <strong>of</strong> DNA and o<strong>the</strong>r <strong>cell</strong><br />

structures. Cytokines<strong>is</strong> (SY-toh-kuh-NEE-sihs) <strong>is</strong> <strong>the</strong> <strong>div<strong>is</strong>ion</strong> <strong>of</strong> <strong>the</strong><br />

parent <strong>cell</strong>’s cytoplasm. Cytokines<strong>is</strong> occurs immediately after mitos<strong>is</strong>.<br />

<strong>Cell</strong> Cycle<br />

The events that happen during <strong>the</strong> life<br />

<strong>of</strong> a <strong>cell</strong> are called <strong>the</strong> <strong>cell</strong> <strong>cycle</strong>.<br />

1<br />

Interphase<br />

The <strong>cell</strong> <strong>cycle</strong> begins<br />

with interphase, which<br />

<strong>is</strong> <strong>the</strong> longest <strong>part</strong> <strong>of</strong><br />

<strong>the</strong> <strong>cell</strong> <strong>cycle</strong>.<br />

<strong>cell</strong> grows and carries<br />

out normal functions;<br />

organelles duplicate<br />

reading tip<br />

The arrows in <strong>the</strong> <strong>Cell</strong> Cycle<br />

diagram represent <strong>the</strong> passage<br />

<strong>of</strong> time. Interphase <strong>is</strong><br />

in red, mitos<strong>is</strong> <strong>is</strong> in purple,<br />

and cytokines<strong>is</strong> <strong>is</strong> in yellow.<br />

INTERPHASE<br />

2<br />

<strong>Cell</strong> Div<strong>is</strong>ion<br />

Phase<br />

After mitos<strong>is</strong> and<br />

cytokines<strong>is</strong> <strong>the</strong>re<br />

are two <strong>cell</strong>s. The <strong>cell</strong><br />

<strong>cycle</strong> <strong>the</strong>n begins<br />

again for each <strong>cell</strong>.<br />

MITOSIS<br />

CYTOKINESIS<br />

Telophase<br />

Anaphase<br />

Metaphase<br />

Prophase<br />

<strong>cell</strong> grows<br />

and prepares<br />

for mitos<strong>is</strong><br />

DNA replicates<br />

and chromosomes<br />

duplicate<br />

Chapter 3: <strong>Cell</strong> Div<strong>is</strong>ion 81<br />

EA


As a result <strong>of</strong> mitos<strong>is</strong> and cytokines<strong>is</strong>, <strong>the</strong> original—or parent—<br />

<strong>cell</strong> splits into two genetically identical daughter <strong>cell</strong>s. In th<strong>is</strong> case,<br />

<strong>the</strong> term daughter <strong>cell</strong> does not imply gender. It <strong>is</strong> a term scient<strong>is</strong>ts use<br />

to refer to <strong>the</strong>se new <strong>cell</strong>s. Each daughter <strong>cell</strong> comes from half <strong>of</strong> <strong>the</strong><br />

parent <strong>cell</strong>. Each daughter <strong>cell</strong> also receives a complete set <strong>of</strong> DNA<br />

from <strong>the</strong> parent <strong>cell</strong>.<br />

COMBINATION NOTES<br />

As you read, begin to take<br />

combination notes on <strong>the</strong><br />

main idea: <strong>Cell</strong> <strong>div<strong>is</strong>ion</strong><br />

produces two genetically<br />

identical <strong>cell</strong>s.<br />

<strong>Cell</strong> <strong>div<strong>is</strong>ion</strong> produces two genetically<br />

identical <strong>cell</strong>s.<br />

Recall that many <strong>cell</strong>s in your body are continually dividing into new<br />

<strong>cell</strong>s. The new <strong>cell</strong>s help your body grow, develop, repair itself, and<br />

replace worn-out <strong>part</strong>s. Though your body <strong>cell</strong>s divide at different<br />

rates, <strong>the</strong> same process—mitos<strong>is</strong>—divides <strong>the</strong>ir genetic material.<br />

<strong>Cell</strong> <strong>div<strong>is</strong>ion</strong> produces daughter <strong>cell</strong>s that are genetically identical<br />

to each o<strong>the</strong>r, as well as to <strong>the</strong>ir parent <strong>cell</strong>, which no longer ex<strong>is</strong>ts.<br />

Being genetically identical to <strong>the</strong>ir parent <strong>cell</strong> helps <strong>the</strong> new <strong>cell</strong>s function<br />

properly. A skin <strong>cell</strong>, for example, divides and produces skin <strong>cell</strong>s<br />

genetically identical to it. The new skin <strong>cell</strong>s will function in exactly<br />

<strong>the</strong> same way as <strong>the</strong> parent.<br />

Check Your Reading<br />

How are daughter <strong>cell</strong>s like <strong>the</strong> parent <strong>cell</strong>?<br />

VISUALIZATION<br />

CLASSZONE.COM<br />

Watch <strong>the</strong> process <strong>of</strong><br />

mitos<strong>is</strong> in action.<br />

Steps <strong>of</strong> Mitos<strong>is</strong><br />

The process <strong>of</strong> mitos<strong>is</strong> <strong>is</strong> essential in evenly dividing <strong>the</strong> genetic material<br />

between <strong>the</strong> daughter <strong>cell</strong>s. Although mitos<strong>is</strong> <strong>is</strong> a continuous<br />

process, scient<strong>is</strong>ts divide <strong>the</strong> events <strong>of</strong> mitos<strong>is</strong> into four phases.<br />

1<br />

2<br />

3<br />

Chromosomes form. During prophase, <strong>the</strong> DNA in <strong>the</strong> nucleus <strong>of</strong><br />

a <strong>cell</strong> forms chromosomes. Each chromosome cons<strong>is</strong>ts <strong>of</strong> two<br />

identical chromatids held toge<strong>the</strong>r by a centromere. The membrane<br />

around <strong>the</strong> nucleus d<strong>is</strong>appears.<br />

Chromosomes line up. The chromosomes line up in <strong>the</strong> middle<br />

<strong>of</strong> <strong>the</strong> <strong>cell</strong>. Th<strong>is</strong> stage <strong>is</strong> called metaphase.<br />

Chromosomes separate. During <strong>the</strong> stage called anaphase, <strong>the</strong><br />

chromatids split up, forming two chromosomes. The chromosomes<br />

are pulled to opposite sides <strong>of</strong> <strong>the</strong> <strong>cell</strong>.<br />

4 Nuclei form. A new nuclear membrane forms around each group<br />

<strong>of</strong> chromosomes during telophase. The chromosomes return to<br />

<strong>the</strong>ir threadlike chromatin form.<br />

Mitos<strong>is</strong> <strong>is</strong> fin<strong>is</strong>hed, and <strong>the</strong> <strong>cell</strong>’s genetic material has been divided.<br />

Following telophase <strong>the</strong> parent <strong>cell</strong>’s cytoplasm <strong>is</strong> divided to complete<br />

<strong>the</strong> parent <strong>cell</strong>’s <strong>div<strong>is</strong>ion</strong> into two entirely separate daughter <strong>cell</strong>s.<br />

EA<br />

82 Unit: <strong>Cell</strong>s and Heredity


<strong>Cell</strong> Div<strong>is</strong>ion<br />

Before mitos<strong>is</strong>, <strong>the</strong> <strong>cell</strong>’s DNA <strong>is</strong> copied during interphase.<br />

Interphase<br />

The <strong>cell</strong> has grown<br />

and <strong>is</strong> ready to divide.<br />

The nucleus contains<br />

two complete copies<br />

<strong>of</strong> DNA.<br />

Mitos<strong>is</strong> produces two new <strong>cell</strong>s with identical copies <strong>of</strong> DNA.<br />

1<br />

Chromosomes<br />

form.<br />

Prophase<br />

The nuclear membrane<br />

d<strong>is</strong>appears.<br />

Long strands <strong>of</strong> DNA<br />

condense to d<strong>is</strong>tinct<br />

chromosomes, each<br />

with two chromatids<br />

that are exact copies<br />

<strong>of</strong> each o<strong>the</strong>r.<br />

Chromosome<br />

chromatids<br />

centromere<br />

2<br />

Chromosomes<br />

line up.<br />

Metaphase<br />

Chromosomes line<br />

up in <strong>the</strong> middle <strong>of</strong><br />

<strong>the</strong> <strong>cell</strong>.<br />

3<br />

Chromosomes<br />

separate.<br />

Anaphase<br />

Each chromosome<br />

splits into<br />

two chromatids.<br />

Chromatids pull to<br />

<strong>the</strong> opposite ends<br />

<strong>of</strong> <strong>the</strong> <strong>cell</strong>.<br />

4<br />

Nuclei form.<br />

Telophase,<br />

Cytokines<strong>is</strong><br />

New nuclear<br />

membranes<br />

form.<br />

<strong>Cell</strong> pinches<br />

and divides<br />

Chapter 3: <strong>Cell</strong> Div<strong>is</strong>ion 83<br />

EA


eading tip<br />

As you read about<br />

cytokines<strong>is</strong> refer to <strong>the</strong><br />

images <strong>of</strong> plant and<br />

animal <strong>cell</strong>s on page 85.<br />

Div<strong>is</strong>ion <strong>of</strong> <strong>the</strong> Cytoplasm<br />

Cytokines<strong>is</strong>, or <strong>the</strong> <strong>div<strong>is</strong>ion</strong> <strong>of</strong> <strong>the</strong> parent <strong>cell</strong>’s cytoplasm, immediately<br />

follows mitos<strong>is</strong> in eukaryotic <strong>cell</strong>s. Cytokines<strong>is</strong> differs slightly in animal<br />

<strong>cell</strong>s and plant <strong>cell</strong>s.<br />

During cytokines<strong>is</strong> in an animal <strong>cell</strong>, a fiber ring forms in <strong>the</strong><br />

center <strong>of</strong> <strong>the</strong> dividing <strong>cell</strong>. The fiber ring contracts, pulling <strong>the</strong> <strong>cell</strong><br />

membrane inward. Eventually, <strong>the</strong> <strong>cell</strong> <strong>is</strong> pinched into two<br />

daughter <strong>cell</strong>s.<br />

In a plant <strong>cell</strong>, <strong>the</strong> <strong>cell</strong> wall prevents <strong>the</strong> <strong>cell</strong> membrane from<br />

being pulled inward. A structure called a <strong>cell</strong> plate grows between <strong>the</strong><br />

two new nuclei. The <strong>cell</strong> plate develops into a membrane and eventually<br />

becomes <strong>part</strong> <strong>of</strong> <strong>the</strong> <strong>cell</strong> wall <strong>of</strong> each <strong>of</strong> <strong>the</strong> new <strong>cell</strong>s.<br />

Check Your Reading<br />

How does cytokines<strong>is</strong> differ in plant <strong>cell</strong>s and animal <strong>cell</strong>s?<br />

<strong>Cell</strong> Div<strong>is</strong>ion<br />

How can you model mitos<strong>is</strong>?<br />

PROCEDURE<br />

1<br />

2<br />

Divide <strong>the</strong> poster board into six spaces, and draw arrows from one<br />

space to <strong>the</strong> next to indicate a <strong>cycle</strong>. Label <strong>the</strong> spaces, in order,<br />

“Interphase,” “Prophase,” “Metaphase,” “Anaphase,” “Telophase,”<br />

and “Cytokines<strong>is</strong>.”<br />

In each space, make a model <strong>of</strong> a <strong>cell</strong> and its DNA in <strong>the</strong> indicated phase.<br />

Make sure you represent <strong>the</strong> <strong>cell</strong> membrane, <strong>the</strong> nuclear membrane—when<br />

it <strong>is</strong> present—and <strong>the</strong> DNA.<br />

WHAT DO YOU THINK?<br />

• In which phases <strong>is</strong> <strong>the</strong> nuclear membrane present?<br />

• In which phases <strong>is</strong> <strong>the</strong> DNA present as chromosomes?<br />

• What do <strong>the</strong> arrows in your model show?<br />

SKILL FOCUS<br />

Making models<br />

MATERIALS<br />

• poster board<br />

• markers<br />

•pipe cleaners<br />

• packing peanuts<br />

•glue<br />

• sc<strong>is</strong>sors<br />

• yarn<br />

TIME<br />

30 minutes<br />

CHALLENGE How do you think <strong>cell</strong> <strong>div<strong>is</strong>ion</strong> would<br />

differ in prokaryotic <strong>cell</strong>s? Do you think <strong>cell</strong> <strong>div<strong>is</strong>ion</strong><br />

in prokaryotic <strong>cell</strong>s would be more or less complex<br />

than in eukaryotic <strong>cell</strong>s? Make drawings to show<br />

how you think a prokaryotic <strong>cell</strong> might divide.<br />

EA<br />

84 Unit: <strong>Cell</strong>s and Heredity


Cytokines<strong>is</strong><br />

Cytokines<strong>is</strong> happens in both plant and animal <strong>cell</strong>s.<br />

Animal <strong>cell</strong> The <strong>cell</strong><br />

membrane pinches; membrane<br />

forms around each <strong>cell</strong>.<br />

Plant <strong>cell</strong> A <strong>cell</strong> plate<br />

forms where <strong>the</strong> <strong>cell</strong> wall<br />

will divide <strong>the</strong> two <strong>cell</strong>s.<br />

COMPARE AND CONTRAST How does <strong>the</strong> process <strong>of</strong> cytokines<strong>is</strong> in <strong>the</strong><br />

animal <strong>cell</strong> on <strong>the</strong> left differ from that <strong>of</strong> <strong>the</strong> plant <strong>cell</strong> on <strong>the</strong> right?<br />

The two daughter <strong>cell</strong>s are now completely separated. Each <strong>is</strong><br />

surrounded by a <strong>cell</strong> membrane. Each daughter <strong>cell</strong> has about half<br />

<strong>of</strong> its parent <strong>cell</strong>’s cytoplasm. Though daughter <strong>cell</strong>s are identical to<br />

<strong>the</strong>ir parent <strong>cell</strong>, <strong>the</strong>y are smaller. After <strong>div<strong>is</strong>ion</strong>, <strong>cell</strong>s enter a period<br />

<strong>of</strong> growth, during which <strong>the</strong>y take in <strong>the</strong> resources <strong>the</strong>y need to<br />

increase <strong>the</strong> amount <strong>of</strong> <strong>the</strong>ir cytoplasm and to grow to full size. When<br />

<strong>cell</strong>s are fully grown, <strong>the</strong>y are about <strong>the</strong> same size as <strong>the</strong> parent <strong>cell</strong><br />

was before <strong>div<strong>is</strong>ion</strong>.<br />

Check Your Reading<br />

What happens to <strong>cell</strong>s after cytokines<strong>is</strong>?<br />

KEY CONCEPTS<br />

1. What are <strong>the</strong> two main <strong>part</strong>s<br />

<strong>of</strong> <strong>the</strong> <strong>cell</strong> <strong>cycle</strong>?<br />

2. Describe <strong>the</strong> state <strong>of</strong> a <strong>cell</strong><br />

about to start mitos<strong>is</strong>.<br />

3. How <strong>is</strong> <strong>the</strong> genetic material in<br />

two daughter <strong>cell</strong>s similar to<br />

<strong>the</strong> genetic material in a<br />

parent <strong>cell</strong>?<br />

CRITICAL THINKING<br />

4. Sequence Describe in<br />

order <strong>the</strong> steps that occur<br />

during mitos<strong>is</strong>.<br />

5. Compare and Contrast<br />

How <strong>is</strong> cytokines<strong>is</strong> in plant <strong>cell</strong>s<br />

similar to cytokines<strong>is</strong> in animal<br />

<strong>cell</strong>s? How <strong>is</strong> it different?<br />

CHALLENGE<br />

6. Infer You know that mitos<strong>is</strong><br />

does not happen in prokaryotes.<br />

Do you think cytokines<strong>is</strong><br />

happens in prokaryotes?<br />

Explain your answer.<br />

Chapter 3: <strong>Cell</strong> Div<strong>is</strong>ion 85<br />

EA

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