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Understanding Anesthesiology - The Global Regional Anesthesia ...

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current recommendations from the American Heart Association<br />

are much more restrictive than they have<br />

been in the past.<br />

As discussed, aspiration prophylaxis may be ordered in<br />

high risk patients. This includes agents which decrease<br />

the volume and/or acidity of gastric secretions (ranitidine,<br />

sodium citrate) as well as agents which increase<br />

gastric emptying (metoclopramide).<br />

A history of systemic steroid use may require the delivery<br />

of a peri-operative course of steroids in order to<br />

avoid the consequences of adrenal suppression which<br />

may present as an Addisonian crisis. Adrenal suppression<br />

occurs when a patient receives longterm exogenous<br />

steroids in daily dose equal to or greater than 10<br />

mg. Once adrenal suppression has occurred, the adrenal<br />

gland takes approximately 3 months to recover<br />

function (after steroid discontinuation). <strong>The</strong>refore, steroid<br />

supplementation is required for patients who are<br />

currently on exogenous steroids or have discontinued a<br />

longterm course in the past three months. <strong>The</strong> amount<br />

and duration of supplemental steroid coverage required<br />

depends on the invasiveness of the surgery. For<br />

minor surgery, a single dose of hydrocortisone (25 mg)<br />

suffices, while for major surgery, the patient requires<br />

100 mg of hydrocortisone daily for 2-3 days.<br />

37

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