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Understanding Anesthesiology - The Global Regional Anesthesia ...

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Pseudocholinesterase deficiency<br />

Pseudocholinesterase deficiency is an inheritable enzyme deficiency of the enzyme that<br />

breaks down succinylcholine. Those affected will demonstrate prolonged effect of succinylcholine.<br />

Deficiency can result as a genetic defect, as a consequence of various medications or a result<br />

of liver disease. <strong>The</strong> latter two causes are usually relative while the genetic defect can produce<br />

a complete lack of pseudocholinesterase function in homozygous individuals. Individuals<br />

who are heterozygous have reduced (but still measurable) pseudocholinesterase activity.<br />

Related Glossary Terms<br />

Succinylcholine<br />

Index<br />

Find Term<br />

Chapter 3 - General <strong>Anesthesia</strong><br />

Chapter 6 - Muscle Relaxants<br />

Chapter 6 - Muscle Relaxants

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