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Understanding Anesthesiology - The Global Regional Anesthesia ...

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Malignant hyperthermia<br />

Malignant hyperthermia (MH) is a potentially life-threatening pharmacogenetic disorder<br />

characterized by the onset of a hypermetabolic crisis in response to certain triggers. Since the<br />

usual triggers are succinylcholine and volatile anesthetics, MH is known as “the anesthesiologist’s<br />

disease”.<br />

Immediate discontinuation of triggering agents is key if an MH reaction is suspected. Dantrolene,<br />

a direct skeletal muscle relaxant, is the only specific treatment for an MH reaction.<br />

Active cooling of the hyperthermic patient may also be required.<br />

Related Glossary Terms<br />

Dantrolene, Desflurane, Forced air warming system, Isoflurane, Myoglobinuria, Ryanodine,<br />

Sevoflurane, Succinylcholine<br />

Index<br />

Find Term<br />

Chapter 3 - General <strong>Anesthesia</strong><br />

Chapter 3 - General <strong>Anesthesia</strong><br />

Chapter 3 - General <strong>Anesthesia</strong><br />

Chapter 5 - Malignant Hyperthermia<br />

Chapter 6 - Muscle Relaxants<br />

Chapter 6 - Muscle Relaxants<br />

Chapter 6 - Inhaled Agents<br />

Chapter 6 - Inhaled Agents<br />

Chapter 6 - Inhaled Agents<br />

Chapter 6 - Inhaled Agents<br />

Chapter 6 - Inhaled Agents<br />

Chapter 6 - Inhaled Agents<br />

Chapter 6 - Miscellaneous

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