Final Programme - The British Society for Rheumatology

Final Programme
BSR Annual Meeting 08-11 May 2007
& BHPR Spring Meeting 09-11 May 2007
International Convention Centre, Birmingham, UK
www.bsrconference.org.uk
Printed with the assistance of:

Acknowledgements
The British Society for Rheumatology would like to thank the following
companies for their contribution to the success of the 2007 Annual
Meeting, in particular for support in the areas listed below:
Abbott for their support of the BSR Innovations in Rheumatology Awards.
Eli Lilly & Co Ltd for their support of the BSR Osteoporosis Award
Pfizer for their support of the BSR Medical Student Bursaries
Roche for supporting the printing of the event announcements and final
programme as well as their sponsorship of the delegate bags
Schering Plough for their support of the BSR Young Investigator Awards.
Servier Laboratories Ltd for providing the delegate pads and pens.
Wyeth for sponsoring the Abstracts on CD-Rom and the registration area,
and for providing lanyards for delegates.
Abbott, Actelion, Roche, Schering Plough and Wyeth for supporting the
provision of educational satellite symposia for delegates.
Additionally, we would like to thank all exhibitors for their continued
support in providing added depth and colour to the BSR Annual Meeting
through an interactive exhibition.
BSR, Bride House, 18-20 Bride Lane, London EC4Y 8EE
Telephone: +44 (0) 207 842 0900 Fax: +44 (0) 207 842 0901
Email: conferences@rheumatology.org.uk
Website: www.rheumatology.org.uk www.bsrconference.org.uk
A Company limited by guarantee with charitable status VAT No. 404 5637 66
Company Reg. No. 3470316 Charity Reg. No. 1067124

Contents
General Information 2
BSR Prizes and Awards 4
Venue Layout Diagram 6
Meeting at a glance 7
Scientific Programme Tuesday 11
Scientific Programme Wednesday 19
Scientific Programme Thursday 29
Scientific Programme Friday 37
Poster Viewing 1 Wednesday 43
Poster Viewing 2 Thursday 61
Poster Viewing 3 Friday 79
Exhibition Floor Plan 95
Exhibitors Details 96
Abstract Reviewers 104
1

General Information for Delegates:
Delegate Code of Conduct
By registering to attend the BSR Annual Meeting or the BHPR Spring Meeting, you have agreed to abide by a code of
conduct. Failure to do so may result in your expulsion from the meeting. No refund will be due in this instance.
• The BSR cannot guarantee capacity in any particular session. Although we will do our best to avoid
disappointment, there may be occasions when a room is full. Legally we are not allowed to let you into
a room in this circumstance and neither BSR or venue staff will tolerate verbal abuse.
• Badges must been worn, in plain sight, at all times. If your badge is lost, immediately report to the
registration desk for a replacement.
• Delegates are responsible for all their property. Neither the BSR or the venue accept liability for loss
or damage of personal items.
• Bags and packages must be in your possession at all times. The safety and security of delegates is
paramount and unattended items may cause security alerts.
Name Badges
Your name badge permits you access to all scientific sessions on the days for which you have registered. Exceptions
apply only where previously specified (ie. Meet the Expert Workshops) or where the session room has reached its
capacity. You are also permitted access to the Exhibition Hall during open hours.
The new electronic badging system has been put in place for your safety and to ensure spaces in sessions are only
taken by people who are entitled to be there.
It is essential that you visibly display your badge at all times as BSR personnel will not allow persons without badges to
access sessions or exhibition areas.
We appreciate your patience and understanding should badge scanning delay your entry to a session and ask that you
arrive as early as possible to ensure access.
Important Fire Safety Information
Seating capacity in all sessions is set according to Fire Safety regulations and cannot be exceeded.
Standing in the aisles or against walls is not permitted in any circumstances and will result in you
being asked to leave the session room.
To assist in the smooth and prompt running of all sessions we ask that delegates do the following:
• Seat yourself as far forward as possible and start seating in the centre of the row.
• Fill all seats from the centre, ensuring that spare seats are on the outside of rows and therefore
obvious and easy to access for late comers.
• If you are not permitted entry to a full session, please step back from the door and form a queue.
You will only be admitted entry if others leave.
Abstract Supplement
As usual, all accepted abstracts have been published as a supplement the journal Rheumatology. In 2007 a
complimentary copy of this supplement has been provided for all delegates on arrival at the event, this will already be
in your delegate pack given to you at the registration desk. Subscribers to the journal will also have received a CD-Rom
version in advance of the meeting and abstracts are available online at http://rheumatology.oxfordjournals.org.
A limited number of additional hard copies will be available at a cost of £10 from the registration desk.
Catering
Your registration fee for the conference includes lunch, tea and coffee for each day that you are registered. All catering
will be served within the main exhibition in Hall 3, please refer to the “Meeting at a Glance” section for timings.
2

CPD
We have been informed by the CPD office of the Royal College of Physicians that we are limited to
6 credits per day. Therefore, the annual meeting will accrue you the following:
Tuesday 08 May 2007 6 Wednesday 09 May 2007 6
Thursday 10 May 2007 6 Friday 11 May 2007 4
A certificate of attendance is included in your delegate bag.
Speaker Preview
Check-in is expected of all speakers - The speaker preview room is located in the Media Suite on the
registration level near Hall 1. Please check-in to the speaker preview room to upload or check your
presentation on arrival at the ICC and no later than 2 hours prior to your session start time.
Disclaimer
Please note that the BSR accepts no responsibility for views expressed by speakers at the event.
Onsite Contacts
If you have a query onsite regarding the BSR Annual Meeting, please contact a member of the
organising secretariat through the registration desk.
Hannah Gardner – BSR Events Officer
Stephanie Tame – BSR Senior Events Officer
Julia Kermode – BSR Head of Education and Events
Local Information
If your query relates to the ICC or the local area, please visit the ICC Information Desk.
Accommodation Agents Contact Details
Please do not contact the BSR with any accommodation queries as unfortunately we will unable to assist you.
However, if you have booked through our appointed accommodation agents, Virtuoso, you can contact them directly
on: Tel: 00 44 (0) 1707 373 464 Fax: 00 44 (0) 1707 373 078 Email: hotels@virtuosoltd.com
Prayer space
A quiet, non-denominational room will be available to anyone requiring space and privacy for prayer during
the meeting. This is located on the concourse level, near Café Vite.
Under 16s
Unfortunately it is not permissible for children under the age of 16 to have access to the meeting
because we do not have sufficient liability insurance to cover a minor should it be required.
No Smoking
Please note that all areas of the conference and exhibition are designated non-smoking.
We ask that you refrain from smoking within the venue.
First Aid
Trained first-aiders will be on duty throughout the events opening hours; please contact one of the
Organisers or the ICC staff.
Business Centre
The ICC offer limited complimentary wireless access for delegates to the conference, please ask at the
registration desk for more details.
Fax, photocopying etc is available via the ICC Business Centre / Information Desk. This is located off
the main concourse, near the box office. Charges will apply.
3

BSR Prizes and Awards
Prize giving ceremony
The Prize giving ceremony will be held at the beginning of the Interactive Evening,
Hall 1, Tuesday 08 May 2007 at 19:30hrs.
Prizes poster displays
The prize winning posters will be displayed in the Prizes section of the poster boards, which will be situated in
the registration area outside Hall 3
Innovation in Rheumatology Awards supported by
Abbott Immunology
Present from Abbott will be: Dr Jackie Harris, Divisional Director, Abbott UK
Innovation in Practice (Category 1)
Cristina Estrach
Title: Aintree Early Arthritis Clinic
Innovation in Development (Category 2)
Lesley Kay
Title: Research Based Education in Rheumatology
Young Investigator Award supported by Schering Plough
Present from Schering Plough will be: Dr Gordon Coutts,
General Manager, Schering Plough UK and Ireland
Shahir Hamdulay (#OP25)
Title: Statins and Rapamycin: Therapeutic Synergy in Vascular Cytoprotection
Sara Carty (#OP55)
Title: Combination Therapy with Etanercept and Sgp130 for Rheumatoid Arthritis is More Effective than Monotherapy
Karolina Wartolowska (#OP19)
Title: Clinical and Experimental Pain Processing in Rheumatoid Arthritis Patients Treated With Anti-TNF
Hector Chinoy (#OP28)
Title: The Diagnostic Utility of Serology Testing for Predicting the Risk of Cancer-Associated Myositis
Francesca Barone (#OP33)
Title: Aberrant Expression of B Cell Survival Factors in Salivary Gland’s Malt Lymphomas during Sjogren’s Syndrome
Zoe Betteridge (#OP32)
Title: Anti-Sumo E1: A Novel Autoantibody in Dermatomyositis Directed Against the Small Ubiquitin-Like Modifier
Activating Enzyme
4

Osteoporosis Award supported by Ely Lilly
Present from Eli Lilly will be: Mr Jeffrey Howe, National Sales Manager
Nicholas Harvey (#OP8)
Title: Childhood Physical Activity is Associated with Bone Mass at 4 Years
Medical Student Bursaries
These posters will be displayed in the Prizes Section, which is situated in registration area,
on Wednesday 9th and Thursday 10th May only. Please take the time to go along and talk
to the Students about their abstracts and interest in Rheumatology.
Michael O’Malley
Correlates of Sleep Disturbance in Rheumatoid Arthritis Patients
Gillian Norrie
Socio-Economic Position in Childhood and Adulthood Independently Predict Chronic Widespread Pain in
Adult Life - Results from a Large Prospective Cohort Study (The 1958 British Birth Cohort Study)
Natalie Smith
A Comparison of the Efficacy of Etanercept in the Treatment of Rheumatoid Arthritis and Psoriatic Arthritis
Thomas Fairfax
Oxygen-Sensitive Acid Extrusion in Articular Chondrocytes
Eleanor Romaine
Can an Aggressive DMARDStrategy Prevent the Need for Biological Therapy? A Pragmatic Observational Study
5

Additional Meetings
By Invitation Only
Date & Time Meeting Name Room
Tuesday 08 May 2007
13:00-14:30 Rheumatology Editorial Board Meeting Hall 7a
Wednesday 09 May 2007
13:00-14:30 Physiotherapists Meeting Hall 4
13:00-14:30 Musculoskeletal Care Editorial Board Meeting Hall 7a
13:00-17:00 CAC and Peer Review Meetings Hall 7b
15:00-16:30 CARDERA 2 Trials Meeting Artists Lounge
Thursday 10 May 2007
08:00-09:00 ERAN AGM Hall 7b
08.00-10.00 ESC Working Group on Undergraduate Education Artists Lounge
14:30-16:30 Website Editorial Board Meeting Artists Lounge
Friday 11 May 2007
07:30-08:30 BSR BR Control Centre Meeting Hall 7a
11:45-12:45 UK Scleroderma Study Group Meeting Artists Lounge
13:00-14:30 MIPA Meeting Artists Lounge
Open Meetings
Date & Time Meeting Name Room
Tuesday 08 May 2007
13:00-14:30 BSR Standards, Guidelines and Audit Working Group Open Meeting Hall 8
Wednesday 09 May 2007
13:00-14:30 BSR Biologics Register Open Meeting Hall 11
13:00-14:30 RATs Meeting Hall 9
13:00-14:30 Delivering higher Standards of Care: ARMA’s tools for service improvement Hall 8
Thursday 10 May 2007
07:00-08:30 Christian Medical Fellowship Breakfast Hall 7a
Friday 11 May 2007
15:15-17:00 PRCA/COT SS Meetings Hall 10 a/b
As usual all rooms are in high demand throughout the BSR Annual Meeting and the turnaround time between sessions
is very tight, therefore it is essential that all meetings/sessions commence and conclude in a timely fashion. Any overrun
will have a severe impact on the remainder of a scientific programme.
If you are attending any of the above meetings please ensure that you arrive promptly in order to avoid a
late start, and any resultant over-run.
7

BSR and BHPR Scientific Programme 2007
Tuesday 08 May 2007
09:30-10:30 Meet the Expert Workshops Executive Rooms
• Sjogrens Syndrome - Exec 1 Simon Bowman & John Hamburger
• Hypermobility - Exec 10 Alan Hakim
• Management of cardiovascular risk in rheumatic disease - Exec 2
George Kitas & Matthew Banks
• Paediatric Rheumatology - Exec 7 Helen Foster
• Difficult Osteoporosis - Exec 8 Roger Francis
• The Rheumatoid Spine - Exec 9 John Mathews
10:30-11:00 Tea/Coffee Hall 3
11:00-13:00 BSR: Role of Protein Modifications in Neo-Antigenicity Hall 10
Chair: Paul Eggleton
• Brief introduction and background from session chair Paul Eggleton
Major self proteins in general should not be antigenic when they appear so it can lead to the
generation of autoantibodies. Some of these autoantibodies have the potential to interfere with
normal physiological processes leading to pathological states.
• Post-transitional modifications of self-antigens Hester Doyle
One way in which immune tolerance can by bypassed is through the post-translational modification
of self-proteins, effectively creating new autoantigens. These modifications occur during a variety of
cellular processes, and alter how both B and T cells respond to the proteins in which they occur .
• Proteomics approaches to the study of modified proteins in human autoimmune diseases
David Perrett
Inflammation can lead via free radical systems to modified proteins. Such changes can be studied
in vitro and in vivo using 3-D fluorescence and proteomic methods such as 2-D electrophoresis and
mass spectrometry
• Generation of neoantigenic epitopes after the post-translational modification of type ll
collagen by factors present within the inflamed joint Ahuva Nissim
Chemical modification of self antigens by oxidants linked to inflammation as a cause of formation
of neoepitopes.
11:00-13:00 BSR: How to manage difficult systemic vasculitis Hall 4
Chair: David G I Scott
• Diagnosis of the systemically ill patient Richard Watts
This talk will cover the major diagnostic features of the systemic vasculitides. It will enable the
participant to make a diagnosis of vasculitis in a systemically unwell patient.
• How to induce and maintain remission David Carruthers
Recent multi-centre clinical trials have provided a firm evidence base for the management of
patients with systemic vasculitis. Data from these studies will be presented as part of this vasculitis
therapy update.
• Treatment after cyclophosphamide David Jayne
Newer treatments for vasculitis will be reviewed. This will include immunesuppressive, such as
leflunomide and mycophenolate mofetil, and biological therapies including rituximab, alemtuzumab
and TNF alpha blockade.
11

13:00-14:30 Lunch Hall 3
• The ENT Enigma: Infection, Vasculitis, something else or a combination Niels Rasmussen
The presentation addresses the complicated aspects of the possible pathogenetic role of Staph.
aureus and the implications for diagnosis, monitoring of disease activity and treatment in
vasculitis (i.e.Wegener's granulomatosis) with involvement of the upper respiratory tract.
BSR Standards, Guidelines and Audit Working Group Open Meeting Hall 8
(Lunch will be available at the meeting)
• Welcome and Introduction – Tom Kennedy
- Welcome to the new Chair of Standards, Guidelines and Audit Working Group
• Guideline Presentations
- The Management of Polymyalgia Rheumatica (PMR) and GCA
Dr. Bhaskar Dasgupta, Consultant Rheumatologist, Southend Hospital
- Pain Guideline
Dr Anthony Jones, Consultant Rheumatologist, Manchester University Rheumatic Disease Centre
- The Management of Rheumatoid Arthritis – After 2 years
Dr Raashid Luqmani, Consultant Rheumatologist, Nuffield Orthopaedic Centre
2007 – 2009 guideline cycle: Discussion – Tom Kennedy
14:30-16:40 BSR: Post-Translational Modifications, Apoptosis and Lipid Oxidation Hall 10
Chair: Paul Winyard
• Brief introduction and background from session chair Paul Winyard
The dysregulation of apoptosis and apoptotic cell clearance has been linked to autoimmune
diseases. This short talk will briefly introduce the concept that apoptotic cells provide a reservoir of
post-translationally modified, antigenic, proteins. Antigenic proteins might arise from modifications
including oxidation and proteolysis, as will be discussed in the talks to follow.
• Altered “self” in dying cells: apoptotic proteases Antony Rosen
This talk will focus on modifications of autoantigen expression and structure in the target tissue in
systemic autoimmunity, and the potential relevance to the initiation and propagation of systemic
autoimmune diseases.
• Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory
Joseph L. Witztum MD
Cells undergoing apoptosis are subject to oxidative stress and consequently a variety of cellularlipids
and proteins are modified generating a variety of post-translational "oxidation-specific" epitopes. We
have shown that many of these are immunogenic. In addition to adaptive immune responses these
epitopes are the target of innate immunity, including natural antibodies and scavenger receptors.
Such defenses are necessary as some of these oxidized lipids have proinflammatory properties.
• Abstract presentations (16:00 – 16:40)
• Functional Consequences of Post-translation Collagen-II Nitration in the joint: A novel
mechanism for perpetuating inflammation? M Whiteman & J-T Schantz
• Title to be confirmed H R Griffiths et al
• Are rheumatoid arthritis associated sugar changes exclusive to IgG or a reflection of a broader
shift in galactosylation? A Alavi et al
12

14:30-16:30 BSR: Osteoarthritis Hall 4
Chair: Fraser Birrell
• Clinical & Epidemiological Perspective Nigel Arden
This talk will summarise the latest updates on the epidemiology and risk factors for osteoarthritis,
focusing mainly on osteoarthritis of the knee.
• Imaging Phil Conaghan
Whereas radiographs have been the standard for evaluating structural progression, modern
imaging offers the potential to improve osteoarthritis patient phenotypes with whole organ
evaluation. Imaging advances related to both OA pathogenesis and outcome assessment will be
reviewed.
• Biomarkers Virginia Kraus
Considerations related to the use of osteoarthritis biomarkers for investigation of osteoarthritis
pathogenesis, as clinical trial endpoints, and for incorporation into an evidence based medicine
approach to clinical care.
• Exercise & Orthotics Mike Hurley
This presentation reviews the current evidence supporting the use of exercise and orthotics in the
management of osteoarthritis. The emphasis will be on those interventions that are practicable
within the current clinical context of the health service
• Symptomatic Treatment Mike Doherty
Evidence-based recommendations concerning pharmacological and non-pharmacological
treatments to relieve symptoms of osteoarthritis will be presented and discussed in terms of
efficacy, side-effects, logistics and patient acceptability.
• Disease Modifying Treatment Paul Dieppe
First we need to define what is meant by 'disease modifying therapy' and think hard about what we
are trying to do for people with OA and why. Three therapeutic approaches that might be 'disease
modifying' will be briefly discussed - mechanical interventions, behavioural changes, and drugs.
14:30-16:30 BSR: Biological therapy for rheumatic disease – new agents and novel indications Hall 1
Chairs: Andy Cope
• Beyond rheumatoid arthritis – the future of TNFα antagonism Peter Taylor
Chronic inflammatory disorders share generic features of inflammation. For many such disorders,
but not all, the therapeutic success of anti-TNF therapy confirms a pathogenic role for TNF .
• Blocking innate immune responses and combination biological therapy Iain McInnes
Based on the success of TNF blockade, there is considerable interest in identifying new cytokine
targets. The relative potential of IL-6, IL-17, IL-12 superfamily and IL-1 superfamily members will be
explored.
• T cell directed biological therapies for rheumatoid arthritis John Isaacs
Therapies that target T-cells have the potential to reset tolerance mechanisms, thereby providing
long-term benefit from a short-term intervention. Anti-CD3 has proved beneficial in type 1 diabetes
and trials are now being planned in rheumatoid arthritis. A key requirement is the definition of
biomarkers of therapeutic tolerance induction.
• Antagonising co-stimulatory molecules in rheumatoid arthritis Paul Emery
The need for a second signal to fully activate T-cells has been known for some time.
Co-stimulatory blockers are capable of blocking this signal and limiting T-cell activation. This
inhibition has a number of consequences. The basic principles of this approach and the practical
data will be reviewed in this talk.
16:30-17:00 Tea/Coffee Hall 3
13

17:00-18:30 BSR: Post-Translationally Modified Proteins in the Discovery of New Diagnostic Markers
Hall 10
Chair: Antony Rosen
• Proteomics of articular cartilage; a disease phenotype in osteoarthritis? Robin Wait
Proteomic strategies provide powerful methods for comparison of protein expression in diseased and
healthy tissue, and reveal a characteristic molecular signature in cartilage from osteoarthritis patients
• Phosphorylation – PTPN22 gene variant Ann Begovich
A large-scale genetic association study has identified a functional missense SNP in the
hematopoietic-specific protein tyrosine phosphatase, PTPN22, that is a risk allele for RA.
The natural history of this SNP and it's role in RA pathogenesis as well as the role of other putative
autoimmune risk alleles will be discussed.
17:00-18:30 BSR Concurrent Oral presentations of abstracts
Cardiovascular Aspects Of Rheumatic Disease Hall 4
Chair: Deborah Symmons
• OP1 Protein Kinase C (pkc)ε protects human vascular endothelial cells against apoptosis
through induction of BCL-2 and inhibition of Caspase-3
R Steinberg 1 , OA Harari 1 , E Lidington 1 , J Boyle 1 , M Nohadani 1 , M Ohba 2 , A Samarel 3 , DO
Haskard 1 , JC Mason 1 .
1
Eric Bywaters Centre, Imperial College, London, United Kingdom; 2 Inst Molecular Medicine, Showa
University, Tokyo, Japan; 3 Cardiovascular Institute, Loyola University, Chicago, IL, United States
• OP2 Methotrexate does not contribute to hyperhomocysteinaemia in rheumatoid arthritis
KMJ Douglas 1 , V Panoulas 1 , J Smith 2 , G Metsios 3 , A Stavropoulas-Kalinogloun 3 , P Nightingale 4 ,
GJ Treharne 1 , GD Kitas 1 .
1
Department of Rheumatology, Dudley Group of Hospitals, Dudley, West Midlands, United Kingdom;
2
Department of Biochemistry, Dudley Group of Hospitals, Dudley, West Midlands, United Kingdom;
3
School of Sport, Performing Arts and Leisure, University of Wolverhampton, Wolverhampton, West
Midlands, United Kingdom; 4 Department of Medical Statistics, University of Birmingham,
Birmingham, West Midlands, United Kingdom
• OP3 Do measurements of carotid intima-media thickness and exercise tolerance test help in
the assessment of cardiovascular risk in ankylosing spondylitis patients? A prospective
matched-cohort study
MM Bakr, A Beale, E Barnes, K Bescod, D Collins, E Price, L Williamson.
1
Rheumatology, Great Western Hospital, Swindon, United Kingdom; 2 Radiology, Great Western
Hospital, Swindon, United Kingdom; 3 Cardiology, Great Western Hospital, Swindon, United Kingdom;
4
Radiology, Great Western Hospital, Swindon, United Kingdom; 5 Rheumatology, Great Western
Hospital, Swindon, United Kingdom; 6 Rheumatology, Great Western Hospital, Swindon, United
Kingdom; 7 Rheumatology, Great Western Hospital, Swindon, United Kingdom
• OP4 Association of cardiovascular risk with renal dysfunction in patients with
rheumatoid arthritis
DG Daoussis 1 , KMJ Douglas 1 , VF Panoulas 1 , IA Antonopoulos 1 , GJ Treharne 1 , PG Nightingale 2 ,
GD Kitas 1 .
1
Rheumatology, Russell’s Hall Hospital, DGOH, Dudley, Birmingham, United Kingdom; 2 Wellcome
Trust, Clinical Research Facility, Queen Elizabeth Hospital, Birmingham, United Kingdom
14

• OP5 Hospital admissions for cardiovascular disease are increased in patients with
inflammatory arthritis: results from a primary-care based inception cohort
JP Franklin 1 , M Lunt 1 , D Bunn 2 , DPM Symmons 1 .
1
arc Epidemiology Unit, The University of Manchester, Manchester, United Kingdom; 2 Norfolk
Arthritis Register, Norfolk and Norwich University Hospital, Norwich, United Kingdom
• OP6 The interaction between the HLA-DBR1 shared epitope, smoking and anti-CCP
antibodies is associated with high premature all cause and CVD mortality in patients with
inflammatory polyarthritis
TM Farragher 1 , NJ Goodson 1 , H Nasseem 1 , D Bunn 2 , W Thomson 1 , DPM Symmons 1 , A Barton 1 .
1
arc Epidemiology Unit, The University of Manchester, Manchester, United Kingdom; 2 Norfolk
Arthritis Register, Norfolk and Norwich Hospital, Norfolk, United Kingdom
Osteoporosis Hall 8
Chair: Nigel Arden
• OP7 Maternal diet during pregnancy and childhood bone mass at aged 9 years:
a longitudinal study
ZA Cole 1 , MK Javaid 1 , P Taylor 1 , C Gale 1 , S Robinson 1 , EM Dennison 1 , KM Godfrey 1 , C Cooper 1 .
1
Medical Research Council Epidemiology Resource Centre, Southampton General Hospital,
Southampton, Hampshire, United Kingdom
• OP8 Osteoporosis Award Winner: Childhood physical activity is associated with bone
mass at 4 years
NC Harvey 1 , K Westgate 2 , S Brage 2 , L Greenaway 1 , J Poole 1 , P Taylor 1 , E Dennison 1 , K Godfrey 1 ,
H Inskip 1 , N Wareham 2 , U Ekelund 2 , C Cooper 1 .
1
MRC Epidemiology Resource Centre, Southampton, Hampshire, United Kingdom;
2
MRC Epidemiology Unit, Cambridge, Cambridgeshire, United Kingdom
• OP9 Vigorous physical activity at aged 9 increases the risk of childhood fractures,
despite also increasing bone mass
EM Clark 1 , AR Ness 2 , JH Tobias 1 .
1
Department of Rheumatology, University of Bristol, Bristol, United Kingdom; 2 Department of
Social Medicine, University of Bristol, Bristol, United Kingdom
• OP10 Do early environment and adult lifestyle interact to determine osteoporosis risk?
Results from the Hertfordshire cohort study
MM Moinuddin 1 , K Jameson 1 , AA Sayer 1 , H Martin 1 , S Robinson 1 , C Cooper 1 , EM Dennison 1 .
1
MRC Epidemiology Resource Centre, University of Southampton, Southampton, Hampshire,
United Kingdom
15

• OP11 Effect of once-yearly infusion of zoledronic acid 5 mg in postmenopausal women
with osteoporosis
R Eastell 1,16 , DM Black 5,16 , JA Cauley 8,16 , F Cosman 9,16 , SR Cummings 5,16 , PD Delmas 6,16 , EF Eriksen 13,16 ,
WD Fraser 4,16 , T Hue 5,16 , P Lakatos 10,16 , PC Leung 11,16 , Z Man 12,16 , AR McLellan 3,16 , P Mesenbrink 14,16 ,
DM Reid 2,16 , IR Reid 7,16 , SR Boonen 15,16 .
1
Metabolic Bone Centre, Northern General Hospital, Sheffield, South Yorkshire, United Kingdom;
2
Medicine and Therapeutics, Medical School Foresterhill, Aberdeen, United Kingdom; 3 Division of
Cardiovascular Sciences and Medicine, Gardner Institute, Western Infirmary, Glasgow, United
Kingdom; 4 Department of Clinical Chemistry, University of Liverpool, Liverpool, United Kingdom;
5
Department of Epidemiology and BioStatistics, University of California at San Francisco, San
Francisco, CA, United States; 6 Service de Rhumatologie et de Pathophysiologie Osseuse, University
Claude Bernard, Lyon, France; 7 Dept of Medicine, University of Aukland, Aukland, New Zealand;
8
Dept of Epidemiology, University of Pittsburgh, Pittsburgh, PA, United States; 9 Clinical Research
Center, Helen Hayes Hospital, West Haverstraw, NY, United States; 10 Belgyogyaszati Klinika,
Semmelweis University, Budapest, Hungary; 11 Dept of Orthopaedics and Traumatology, Chinese
University of Hong Kong, Hong Kong, China; 12 Centro Tiempo, Buenos Aires, Argentina; 13 CRD,
Novartis Pharma AG, Basel, Switzerland; 14 BioStatistics, Novartis Pharma AG, East Hanover, NJ,
United States; 15 Centre for Metabolic Bone Diseases, Leuvan Univsersity, Leuvan, Belgium; 16 For the
HORIZON-Pivotal Fracture Trial (PFT) Research Group, San Francisco, CA, United States
• OP12 Prevalence and factors associated with injury falls among adults aged 45+
with arthritis
JM Hootman 1 , LC McGuire 1 , J Stevens 2 .
1
Division of Adult and Community Health, Centers for Disease Control and Prevention, Atlanta, GA,
United States; 2 Division of Unintentional Injury Prevention, Centers for Disease Control and
Prevention, Atlanta, GA, United States
Connective Tissue Diseases Hall 5
Chair: Simon Bowman
• OP13 Scleroderma renal crisis – patient characteristics and outcomes in 110 cases from a
single centre
H Penn 1 , AJ Howie 2 , EJ Kingdon 3 , CC Bunn 4 , RJ Stratton 1 , CM Black 1 , A Burns 5 , CP Denton 1 .
1
Department of Rheumatology, Royal Free Hospital, London, United Kingdom; 2 Department of
Pathology, University College London, London, United Kingdom; 3 Department of Nephrology, Royal
Sussex County Hospital, Brighton, United Kingdom; 4 Department of Clinical Immunology, Royal Free
Hospital, London, United Kingdom; 5 Department of Nephrology, Royal Free Hospital, London, United
Kingdom
• OP14 Reduction of fatigue in sjogren’s syndrome with rituximab: results of a randomised,
placebo-controlled study
S Dass 1 , SJ Bowman 2 , EM Vital 1 , K Ikeda 1 , CT Pease 1 , P Emery 1 .
1
Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, West Yorkshire, United
Kingdom; 2 Department of Rheumatology, University Hospitals NHS Trust, Birmingham, West
Midlands, United Kingdom
• OP15 1H magnetic resonance spectroscopy reveals abnormalities in the basal ganglia of
patients with neuropsychiatric lupus
PL Peterson 1 , FA Howe 2 , JS Axford 1 .
1
Rheumatology Department, St George’s Hospital NHS Trust, London, United Kingdom; 2 Basic
Medical Sciences, St George’s, University London, London, United Kingdom
16

• OP16 Is intimal hyperplasia on temporal artery biopsy a marker of neuro-ophthalmic
complications of GCA?
D Makkuni 1 , K Wolfe 2 , A Hutchings 3 , B Dasgupta 1 .
1
Rheumatology, Southend University Hospital, Westcliff on Sea, Essex, United Kingdom;
2
Pathology, Southend University Hospital, Westcliff on Sea, Essex, United Kingdom; 3 Health
Services Research Unit, London School of Hygiene & Tropical Medicine, London, United Kingdom
• OP17 Recombinant domain I of β2Glycoprotein I ameliorates thrombosis induced by
antiphospholipid antibodies in mice
Y Ioannou 1 , T Harper 2 , Z Romay-Penabad 2 , I Giles 1 , C Pericleous 1 , A Rahman 1 , S Pierangeli 2 .
1
Centre for Rheumatology, University College London, London, United Kingdom; 2 Division of
Rheumatology, The University of Texas Medical Branch, Galveston, TX, United States
• OP18 Epidemiology of anca-associated vasculitis in the UK and Japan
RA Watts 1 , DG Scott 1 , DJ Jayne 2 , S Kobayashi 3 , K Suzuki 4 , H Hashimoto 3 , S Fujimoto 5 , T Ito-Ihara 6 ,
H Nunoi 5 .
1
School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, United
Kingdom; 2 Department of Medicine, Addenbrooke’s Hospital, Cambridge, United Kingdom;
3
Juntendo University School of Medicine, Tokyo, Japan; 4 Institute of Infectious Diseases, Tokyo,
Japan; 5 Miyazaki University, Miyazaki, Japan; 6 Division of Nephrology, Kyoto University Graduate
School of Medicine, Kyoto, Japan
The Patients Perspective Hall 1
Chair: Ross Wilkie
• OP19 Young Investigator Award Winner: Clinical and experimental pain processing in
rheumatoid arthritis patients treated with ANTI-TNF
K Wartolowska 1,2 , P Schweinhardt 1,2 , P Wordsworth 3 , BA Chizh 4 , C Bountra 4 , I Chessell 4 , I Tracey 1,2 .
1
Department of Physiology, Anatomy & Genetics, University of Oxford, Oxford, United Kingdom;
2
Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical
Neurology, University of Oxford, Oxford, United Kingdom; 3 Nuffield Department of Orthopaedic
Surgery, Nuffield Orthopaedic Centre, Oxford, United Kingdom; 4 Pain Research Department,
Neurology and GI Centre of Excellence for Drug Discovery, GlaxoSmithKline Research and
Development Ltd. GlaxoSmithKline, Harlow, United Kingdom
• OP20 Women with fibromyalgia (FMS) produce dramatic and distinctive pain drawings with
diagnostic and therapeutic possibilities
MA Kirkham, JG Jones.
1
School of Sports Health and Exercise Science, University of Wales Bangor, Bangor, North Wales,
United Kingdom; 2 Department of Rheumatology, Ysbyty Gwynedd, Bangor, North Wales, United
Kingdom
• OP21 Differences between patients of asian and caucasian origin in beliefs about disease
modifying anti-rheumatic drugs
K Kumar 1 , C Gordon 1 , V Toescu 1 , CD Buckley 1 , R Horne 2 , P Nightingale 3 , K Raza 1 .
1
Rheumatology, The University of Birmingham, Birmingham, United Kingdom; 2 Centre for
Behavioural Medicine, The School of Pharmacy, University of London, London, United Kingdom;
3
Wellcome Trust Clinical Research Facility, Queen Elizabeth Hospital, Birmingham, United Kingdom
17

• OP22 Health status measures in rheumatoid arthritis: non-equivalent assessments of status
and treatment effects
GH Kingsley 1,2 , B Khoshaba 1 , EH Choy 1,3 , DL Scott 1,3 .
1
Department of Rheumatology, Kings College London School of Medicine, London, United
Kingdom; 2 Department of Rheumatology, University Hospital Lewisham, London, United Kingdom;
3
Department of Rheumatology, Kings College Hospital, London, United Kingdom
• OP23 Why do patients with rheumatoid arthritis often score “states worse than death”
on the EQ-5D?
MJ Harrison 1 , LM Davies 2 , NJ Bansback 3 , MJ McCoy 1 , A Hassell 4 , DPM Symmons 1 .
1
arc Epidemiology Unit, The University of Manchester, Manchester, United Kingdom; 2 HER@M,
The University of Manchester, Manchester, United Kingdom; 3 Centre for Health Evaluation and
Outcome Sciences, St. Paul’s Hospital, Vancouver, Canada; 4 Department of Rheumatology,
University Hospital of North Staffordshire NHS Trust, Stoke-on-Trent, United Kingdom
• OP24 Improved work stability and reduced job loss with adalimumab plus methotrexate in
early rheumatoid arthritis: results of the PRevention Of Work Disability (PROWD) study
V Bejarano 1 , M Quinn 1 , PG Conaghan 1 , AM Keenan 1 , R Reece 1 , D Walker 2 , AK Gough 1 , P Emery 1 .
1
Academic Unit of Musculoskeletal Disease, Univeristy of Leeds, Leeds, West Yorkshire, United
Kingdom; 2 Freeman Hospital, Newcastle, United Kingdom
17:00-18:30 BHPR/arc/BSR: Research training and academic career development tutorials
Executive Rooms
Following the success of the 2006 Academic careers workshops we are again giving you the
opportunity to book a 20 minute one-on-one tutorial with a leading figure in the academic and
research fields. Places will be allocated on a strictly first come, first served basis.
• Krysia Dziedzic
• Elaine Hay
• Dorian Haskard
• Sarah Hewlett
• Tony Redmond
• Alan Silman
• Alison Hammond
18:30-19:30 Welcome Buffet Reception Hall 3
19:30-20:30 Presentation of Prizes & Awards 2007 Hall 1
Immediately preceeding the Interactive Evening join the BSR President in congratulating the 2007
winners of the Innovations in Rheumatology, Young Investigator and Osteoporosis Awards
The Interactive Evening
Chair: Chris Deighton
An interactive audience participation quiz in which Juniors will take on Seniors, and the best
performers will be selected to compete head to head on a non-esoteric clinical case.
18

Wednesday 09 May 2007
07:00-08:30 Satellite Symposia
Schering Plough Hall 5
MISSION: CONTROL
Pushing the frontiers of RA management
Launch Control: - Chairman’s introduction
Iain McInnes, Glasgow University
Gravity of the mission - The burden of inflammation
Chris Edwards, Southampton General Hospital
Mission: Control - Early RA
Mark Quinn, York Hospital NHS Trust
Mission: Control – Established RA
Iain McInnes, Glasgow University
Ground Control – Use of imaging in RA
David Kane, Tallaght Hospital, Dublin
Interactive Q&A session
Mission achieved?
Iain McInnes, Glasgow University
Roche Hall 9
Breaking News at Breakfast
Chair: Kate Silverton
Introduction
Highlighting the Unmet need in RA
Andrew Östör
Measurement of Disease Activity
Ernest Choy
Targeted B-Cell Therapy
Paul Emery
Future of RA Therapy/Treatment
Peter Taylor
Close and Final Q+A
08:30-10:00 BSR: Poster viewing Hall 3
10:00-11:00 Poster Discussions
RA Treatment Hall 5
Chair: Raashid Luqmani
43 Patterns of DMARDand corticosteroid use in newly diagnosed RA patients enrolled in the
early rheumatoid arthritis network (ERAN) database
PDW Kiely, CA Mayes, A Young, Participating ERAN Centers.
1
The Early Rheumatoid Arthritis Network, St Albans City Hospital, St Albans, Herts, United Kingdom
31 Can goal oriented therapy for rheumatoid arthritis improve functional outcome?
NJ Gullick, G Panayi, T Gibson, S Oakley, B Mason, A Vincent, B Kirkham.
1
Department of Rheumatology, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom
19

17 Remission and major clinical response in active rheumatoid arthritis (RA) patients after
adalimumab (Humira®) treatment
GM Burmester 1 , P Wordsworth 2 , F McKenna 3 , GF Farraccioli 4 , R-M Flipo 5 , S Kary 6 , H Kupper 6 .
1
Charité – University Medicine Berlin, Berlin, Germany; 2 Nuffield Orthopaedic Centre, Oxford, United
Kingdom; 3 Trafford General Hospital, Manchester, United Kingdom; 4 Catholic University of Rome, Rome,
Italy; 5 University Hospital, Lille, France; 6Abbott GmbH & Co. KG, Ludwigshafen, Germany
20 Lack of response to first anti-TNFα agent should not preclude alternative anti-TNFα therapy
J Pringle, A Stirling, MM Gordon.
1
Department of Rheumatology, Gartnavel General Hospital, Glasgow, United Kingdom
50 Lipid-lowering with either simvastatin or ezetimibe alters immunological function in patients
with rheumatoid arthritis
SP Fairchild 1 , M Schenk 1 , C Bryson 1 , KM Maki-Petaja 2 , A Furlong 1 , OA Rosenwasser 1 , IB Wilkinson 2 ,
FC Hall 1 .
1
University of Cambridge Department of Clinical Medicine, Addenbrooke’s Hospital, Cambridge, Cambs,
United Kingdom; 2 Clinical Pharmacology Unit, University of Cambridge, Cambridge, United Kingdom
41 Musculoskeletal ultrasound guided joint injections are significantly more accurate than
clinical examination guided joint injections
JR Cunnington 1,2 , PN Platt 2 , G Hide 2 , DJ Kane 1 .
1
School of Clinical Medical Sciences (Dept Rheumatology), Newcastle University, Newcastle upon Tyne,
Tyne and Wear, United Kingdom; 2 Rheumatology, Freeman Hospital, Newcastle upon Tyne, Tyne and
Wear, United Kingdom
Spondylarthropathies Hall 11
Chair: Ellie Korendowych
86 Adalimumab is effective in patients with preradiographic axial spondyloarthritis:
results of a 12-week, randomized controlled trial
H Haibel 1 , M Rudwaleit 1 , F Heldmann 2 , J Listing 3 , R Wong 4 , H Kupper 5 , J Braun 6 , J Sieper 1 .
1
Charité Universitätsmedizin Berlin, Berlin, Germany; 2 St. Josefs-Krankenhaus, Herne, Germany; 3 German
Rheumatism Research Center, Berlin, Germany; 4 Abbott, Parsippany, NJ, United States; 5 Abbott GmbH &
Co KG, Ludwigshafen, Germany; 6 Ruhr University Bochum, Bochum, Germany
92 Non-response to biologic drugs in psoriatic arthritis – “switching” should always
be considered
LC Coates 1 , H Marzo-Ortega 1 , DJ Bryer 1 , A Bennett 1 , AD Fraser 1 , P Emery 1 .
1
Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, West Yorkshire,
United Kingdom
90 The Glasgow MRI Sacroiliitis Score (GMSS) – the application of a new MRI scoring system
to a cohort of ankylosing spondylitis patients
MG Sambrook 1 , K Ong 1 , C Noble 2 , L Mackenzie 3 , D Kane 4 , RD Sturrock 3 .
1
Department of Radiology, Glasgow Royal Infirmary, Glasgow, United Kingdom; 2 Department of
Physiotherapy, Glasgow Royal Infirmary, Glasgow, United Kingdom; 3 Centre for Rheumatic Diseases,
Glasgow Royal Infirmary, Glasgow, United Kingdom; 4 Medicine, St James Hospital, Dublin, Ireland
20

81 Diagnostic reliability of low-field magnetic resonance imaging (MRI) for the study of nail
and distal interphalangeal (DIP) joint in psoriatic arthritis (PsA)
R Scarpa 1 , E Soscia 2 , R Peluso 1 , M Atteno 1 , C Sirignano 2 , L Costa 1 , MND Di Minno 1 , S Iervolino 1 , MA
Cimmino 3 , U Balestrieri 1 , L Satragno 4 , M Salvatore 2 .
1
Dpt of Clinical and Experimental Medicine, Rheumatology Research Unit, University Federico II,
Naples, Italy, Italy; 2 National Council of Research, Radiology Unit - Biostructures and Bioimaging
Institute, University Federico II, Naples, Italy, Italy; 3 Dpt of Internal Medicine, Rheumatology Unit,
University of Genoa, Genoa, Italy, Italy; 4 ESAOTE Group Italy, ESAOTE, Genoa, Italy, Italy
104 Regulatory IL4+CD8+ T cells in as patients and healthy controls
LB Zhang 1 , LB Jarvis 1 , JS Gaston 1 .
1
Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom
94 Genetic susceptibility for psoriatic arthritis – investigation of genes NAT9, SCL9A3R1
AND RAPTOR on chromosome 17q25
CE Filer 1 , A Barton 1 , IN Bruce 1 , J Worthington 1 , P Ho 1 .
1
arc-Epidemiology Unit, The University of Manchester, Manchester, United Kingdom
Genetics Hall 9
Chair: Tim Vyse
70 The relationship of inflammatory and genetic factors with fibrinolysis in rheumatoid
arthritis
KMJ Douglas 1 , V Panoulas 1 , J Smith 2 , M Labib 2 , P Nightingale 3 , GJ Treharne 1 , GD Kitas 1 .
1
Department of Rheumatology, Dudley Group of Hospitals, Dudley, West Midlands, United Kingdom;
2
Department of Biochemistry, Dudley Group of Hospitals, Dudley, West Midlands, United Kingdom;
3
Department of Medical Statistics, University of Birmingham, Birmingham, West Midlands, United
Kingdom
74 A novel splice mutation in TNFRSF1A in a 16 year old male and his mother, both of whom
have TNF-receptor associated periodic syndrome (TRAPS)
SM Churchman 1 , LD Church 1 , B Hayward 1 , S Savic 2 , HC Gooi 2 , P Emery 1 , MF McDermott 1 .
1
Leeds Institute of Molecular Medicine, University of Leeds, Leeds, West Yorkshire, United Kingdom;
2
Immunology, St. James University Hospital, Leeds, West Yorkshire, United Kingdom
68 The search for susceptibility variants for rheumatoid arthritis within the PADI region in a
caucasian population
HM Naseem 1 , J Worthington 1 , AC Barton 1 .
1
ARC Epidemiology Unit, University of Manchester, Manchester, Greater Manchester, United Kingdom
75 Radiological damage in rheumatoid arthritis is associated with IL-6 and IL-10 genotypes
independent of autoantibody production
I Marinou 1 , J Healy 1 , D Mewar 1 , DJ Moore 1 , MC Dickson 2 , MH Binks 2 , DS Montgomery 2 , K Walters 1 ,
AG Wilson 1 .
1
Section of Musculoskeletal Sciences, School of Medicine & Biomedical Sciences, The University of
Sheffield, Sheffield, United Kingdom; 2 GlaxoSmithKline R&D, Stevenage, United Kingdom
69 A whole genome by association of chronic inflammatory arthritis
S John 1 , A Hinks 1 , N Shephard 1 , E Wang 2 , M Cargill 2 , Y Turpaz 2 , A Barton 1 , S Eyre 1 , J Bowes 1 ,
W Thomson 1 , G Kennedy 2 , J Worthington 1 .
1
ARC Epidemiology Unit, University of Manchester, Manchester, United Kingdom; 2 Affymetrix,
Affymetrix Inc, Santa Clara, United States
21

Case Reports Hall 4
Chair: Robert Thompson
133 Hepatotoxicity with sulfasalazine: data from a local surveillance system of serious adverse
events in patients with inflammatory arthritis
P Jobanputra, R Amaresena, F Maggs, E Rankin, S Bowman, R Jubb, D Homer.
1
Department of Rheumatology, Selly Oak Hospital, UHB NHS Foundation Trust, Birmingham, West
Midlands, United Kingdom
128 Methotrexate pneumonitis precipitated by switching from oral to parenteral
administration
CA Kelly, H Aspey, A Todd, V Saravanan, M Rynne.
1
Rheumatology and General Medicine, Queen Elizabeth Hospital, Gateshead, Tyne and Wear, United
Kingdom
131 Cocaine induced midline destructive lesions
SM Rachapalli, PDW Kiely.
1
Rheumatology, St George’s Healthcare NHS Trust, London, United Kingdom
138 Scurvy – a vasculitis mimic
SG Dubey 1 , O Martin 1 , S Karthiga 1 , RA Watts 1 , GP Clunie 1 .
1
Dept of Rheumatology, Ipswich Hospital NHS Trust, Heath Lane, Ipswich, United Kingdom
10:00-11:00 BHPR: Droitwich Medical Trust Lecture: Sarah Hewlett Hall 1
This lecture will explore the problem of fatigue in rheumatoid arthritis and set it within the context of
how greater collaboration with patients is expanding the focus of Rheumatology research.
11:00-11:30 Tea/Coffee Hall 3
11:30-13:00 BSR: Recent Advances in the Clinical Utility of Autoantibody Measurement Hall 10
Chairs: Richard Haigh
• Role of post-translational modifications in neo-antigenicity and subsequent pathology of
connective tissue diseases Ger Pruijn
(Unusual) post-translational modifications have been suggested to play an important role in the
breaking of immunological tolerance to self proteins resulting in autoimmune phenomena. Increasing
evidence supports the generation of neo -epitopes by post-translational modifications in the early
phases of connective tissue diseases and their possible role in pathophysiological processes.
• Clinical utility of anti-citrullinated protein antibodies in the diagnosis of Rheumatoid Arthritis
Thomas Skogh
I will discuss the value of ACPA analysis in the diagnosis of arthritis and prediction of disease course
and outcome. The following questions will be addressed: Does ACPA-positivity identify a uniform
arthritis phenotype? Do different ACPA assays give different information? Is it time to abandon the
rheumatoid factor test?
• Anti-phospholipid antibodies Munther Khamashta
Correct identification of patients with antiphospholipid syndrome is important,because prophylactic
anticoagulant therapy can prevent thrombosis from recurring, and treatment of affected women
during pregnancy can improve fetal and maternal outcome.
22

11:30-13:00 BSR: Paediatrics Hall 4
Chair: Clive Ryder
• Metabolic storage diseases presenting in childhood Ed Wraith
Metabolic storage disorders are inherited and progressive. This talk outlines their variable modes of
presentation, an approach to diagnosis and the advances that have been made in recent years with
regard to therapy
• Problems and solutions in the management of systemic onset JIA Patricia Woo
Systemic juvenile idiopathic arthritis (sJIA) is clinically, pathologically and genetically distinct from
other forms of juvenile arthritides. It is heterogeneous and there is still an unmet need in the
pharmacological treatment of the more severe forms. The lecture will review the latest development
in the managment of sJIA.
• Surgical management of JIA in adolescents and young adults Johan Witt
The operative and non-operative management of joint problems in children and adolescents with
JIA will be discussed, mainly focussing on the hip and knee.
• Management of chronic pain in childhood and adolescents Jacqui Clinch
Chronic musculoskeletal pain in children and adolescents is presenting more commonly in
rheumatology, paediatric and orthopaedic clinics. This overview covers presentation, assessment
and rehabilitation of these difficult conditions.
11:30-13:00 BSR: COXIBs; Much ado about nothing? Hall 1
Chair: Howard Bird
The session will provide an impartial review of the advantages and disadvantages of Coxibs in the
context of older NSAID’s in the light of the most recently published clinical trials.
• The pharmacology view Kay Brune
Collectively, coxibs are as effective as tNSAIDS, they show better GI-tolerability, less
"aspirin-inducible asthma" and inhibition of platelet aggregation, but as tNSAID's, they cause
water retention, increase blood pressure and CI's (strokes).
• The gastro-enterology view Chris Hawkey
GI safety of selective and non selective COX-2 inhibitors: an intelligence -based approach.
• The cardiology view Justin Mason
An evidence based approach will be adopted to establish whether the clinical use of NSAIDs
and COXIBs is associated with a significant cardiovascular risk.
11:30-13:00 BHPR: Service Developments Hall 11
Chair: Candy McCabe & Robert Field
• Musculoskeletal interface clinics - myth or reality Peter Dawes
Configuration of NHS services are rapidly changing with a shift to community based expertise.
Rheumatology has the opportunity to lead and develop at the interface. A department’s view,
experience and challenges of developing and delivering services for musculoskeletal patients at the
interface will be presented.
• Nurse/physiotherapy Ankylosing Spondylitis Clinic Patricia Cornell
Ankylosing Spondylitis clinic - an innovative practitioner and physiotherapist led development.
This session will explore why and how this clinic was developed along with the additional training
needs of the practitioners. Patient feedback and the advantages and disadvantages of this clinic
will also be discussed.
• Combined liaison psychiatry clinic Sarah Ryan
This presentation will describe the objectives and workings of a combined monthly rheumatology
and liaison psychiatry clinic and include case studies of patients who have attended the service.
• Developing a joint service in primary care (ICATs) Integrated Clinical assessment and
treatment service Anne Browne
An overview of the development of a fully integrated rheumatology, orthopaedic and chronic pain
service in primary care, utilising a specialist personal medical service (SPMS) model as a vehicle
to deliver the care.
23

13:00-14:30 Lunch Hall 3
BSR Biologics Register Open Meeting Hall 11
(Lunch will be available at the meeting)
An open session for all BSR and BHPR members.
• Welcome and introduction - David Isenberg
• BSRBR clinical update - Deborah Symmons & Kimme Hyrich
• Rituximab – coming soon - David Isenberg
• Findings of the consultants survey - Lesley Kay
• Ankylosing Spondylitis: discussion topic - David Isenberg, Lesley Kay & Deborah Symmons
• Q&A Session - David Isenberg
Closing Remarks - David Isenberg
ARMA Open Meeting Hall 8
(Lunch will be available at the meeting)
Climate change: Rheumatology services in a new political environment
This session will look at the current state of rheumatology services and how to effectively influence
future service development in a changing political environment. ARMA will launch the report from
its 2007 survey of rheumatology units and there will be an introduction to practical tools that
rheumatology professionals can use, including the BSR’s new Action Plan for Service Development
& Change and ARMA Local Networks.
Speakers:
Bill Freeman, Director of ARMA
Debbie Smith, Head of External Relations, BSR
Lindsey Wilcox, Physiotherapist and Co -Convenor of the Morecambe Bay ARMA Local Network
RATs Meeting Hall 9
(Lunch will be available at the meeting)
14:30-16:30 BSR/BHPR shared session: plenary oral presentation of abstracts Hall 1
Chair: Jacqueline Hill & Andrew Bamji
OP25 Young Investigator Award Winner: Statins and rapamycin: therapeutic synergy in
vascular cytoprotection
SS Hamdulay, F Ali, N Ali, R Steinberg, E Lidington, DO Haskard, JC Mason.
1
Eric Bywaters Centre, Imperial College, Hammersmith Campus, London, United Kingdom
OP26 Efficacy and safety of abatacept in children and adolescents with active juvenile idiopathic
arthritis (JIA): results of double-blind withdrawal phase
A Block 1 , N Ruperto 2 , DJ Lovell 3 , AM Prieur 2 , E Paz 2 , NE Rubio Perez 2 , CA Silva 2 , C Abud Mendoza 2 ,
R Burgos-Vargas 2 , C Saad-Magalhaes 2 , JA Melo-Gomes 2 , V Gerloni 2 , F Sztajnbok 2 , M Scheinberg 2 ,
LH Sigal 1 , A Covucci 1 , P Cornet 1 , L Pagliaro 1 , G Giannini 3 , A Martini 2 .
1
Bristol-Myers Squibb, Princeton, NJ, United States; 2 PRINTO, IRCCS Istituto G Gaslini, Genoa, Italy;
3
PRCSG, Cincinnati Childrens Hospital Medical Center, Cincinnati, OH, United States
OP27 Prevention of vascular damage in scleroderma: results of a randomised, double-blind,
placebo-controlled trial of the ace-inhibitor quinapril in limited cutaneous systemic sclerosis
AE Gliddon 1 , CJ Dore 2 , PJ Maddison 3 , QUINS Trial Study Group.
1
School of Sport, Health & Exercise Science, University of Wales, Bangor, Bangor, Gwynedd, United
Kingdom; 2 Clinical Trials Unit, Medical Research Council, London, London, United Kingdom;
3
Rheumatology Department, Ysbyty Gwynedd Hospital, Bangor, Gwynedd, United Kingdom
24

OP28 Young Investigator Award Winner: The diagnostic utility of serology testing for predicting
the risk of cancer-associated myositis
H Chinoy 1,2 , N Fertig 3 , CV Oddis 3 , WE Ollier 2 , RG Cooper 1 .
1
Rheumatic Diseases Centre, Hope Hospital, Salford, United Kingdom; 2 Centre for Integrated Genomic
Medical Research, The University of Manchester, Manchester, United Kingdom; 3 Division of
Rheumatology & Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh,
PA, United States
OP29 Illness perceptions of low back pain patients in primary care: are they associated with
outcome?
NE Foster 1 , A Bishop 1 , E Thomas 1 , C Main 1 , R Horne 2 , J Weinman 3 , EM Hay 1 .
1
Primary Care Musculoskeletal Research Centre, Keele University, Keele, Staffordshire, United Kingdom;
2
Centre for Behavioural Medicine, School of Pharmacy, University of London, London, United Kingdom;
3
Health Psychology Section, Guy’s Campus of Kings College London, London, United Kingdom
OP30 The contribution of selected non-articular conditions to knee pain severity in older adults
LR Wood, GM Peat, E Thomas.
1
Primary Care Musculoskeletal Research Centre, Keele University, Keele, Staffordshire, United Kingdom
16:30-17:00 Tea/Coffee Hall 3
17:00-18:00 Heberden Oration Hall 1
Chair: Andrew Bamji
Dorian Haskard
Blood vessels, inflammation and rheumatic diseases
The lecture will focus on how recent insights in vascular biology provide a framework for understanding
the inflammatory nature of atherosclerosis, and how the development of atherosclerosis may be
accelerated in the context of rheumatic diseases.
18:15-19:45 BSR: Special Interest Groups
Cardiovascular co-morbidity in RA Hall 11
Convenor: George Kitas
Cardiovascular comorbidity in chronic disease: an epidemiological puzzle Colin Baigent
Update on TRALIS Frances Hall
The TRACE RA programme: where are we now? Sumitra Smith
TRACE RA: cardiovascular study George Kitas
TRACE RA DAS: RA activity sub-study Deborah Symmons
TRACE RA BIOBANK Jill Belch
Information Technology Hall 8b
Convenor: Marwan Bukhari
Theme: Using information technology to advance our practice
Welcome and introduction. Marwan Bukhari
DMARD monitoring software demonstration
Using touch screen technology in the outpatients Alan Hakim
Email advice and digital transcription of clinic letters Marwan Bukhari
Panel discussion
25

RA Outcomes Hall 8a
Convenor: Adam Young
The effect of extra articular manifestations on RA outcomes G Koduri
Extra articular manifestations & management of pulmonary conditions in RA Clive Kelly & colleagues
Anti TNF therapy in RA: guidance form BSR & NICE Chris Deighton
Soft Tissue Rheumatism & Sports Medicine Hall 7b
Convenor: Cathy Speed
Programme to be announced
Spondyloarthritis Hall 7a
Convenor: Paul Bowness and Millicent Stone
Is AS a progressive disease? Evaluation of Longitudinal clinical and imaging outcomes in Ankylosing
Spondylititis Millicent Stone
Economic Analysis of Response to TNF blockade in AS Annelies Boonen
Update on pathogenesis of PsA Douglas Veale
Biomarkers of Response to TNF blockade in PsA Oliver Fitzgerald
18:15-19:15 RATs Training Workshop Hall 9
'THE FUTURE OF RHEUMATOLOGY TRAINING'
Following on from last years successful inaugural RATS workshop, this years workshop will focus on the
many issues surrounding the future of Rheumatology training in the UK. Topics that we are aiming to
cover are the rapidly evolving areas of Rheumatology restructuring of services with emphasis on how
this may affect training, MMC / PMETB and also how academic training pathways will fit into all of this.
These broad areas will be represented by Drs Andrew Bamji and Deborah Bax with Professor D Haskard
representing the academic training arm. After very short talks from all three speakers, trainees will be
given the opportunity to air concerns and for the speakers to engage in debate. Please attend early to
secure a place as this workshop is also open to non-trainees who have an active interest in training.
20:00-21:30 Satellite Symposia
Onsite
Actelion
PAH & Scleroderma Mastermind Hall 5
Welcome and introduction of contestants – John Humphreys
Scleroderma – Chris Denton
The consequences of vasculopathy – Ariane Herrick
Pulmonary Arterial Hypertension and Scleroderma – David Kiely
Effective screening and monitoring of Scleroderma Patients – Audience Keypad Survey
Questions and close
Abbott Hall 4
There’s more to remission
Chair: Paul Emery, Leeds
Is there more to remission than just signs and symptoms? Paul Emery
The Science behind retardation and structural damage Andrew Oster
Defining Remission: Symptoms vs Disease? Duncan Porter
What is remission in the spondyloarthropathies? Ernest Choy
A Joint Responsibility: Rheumatology services in the new NHS Peter Saggers,
Eastern Specialised Commissioning Group
PROWD: data from the Prevention of Work Disability study Paul Emery
26

Offsite
Wyeth The Banqueting Suite, The Council House
A Question of Joints
Host: Rob Moots
North Team
Lesley Kay, Newcastle
Chris Buckley, Birmingham
Iain McInnes, Glasgow
South Team
Millicent Stone, Bath
Chris Edwards, Southampton
Trish Cornell, Poole
Quick introduction by host
Question of Joints picture board
Mystery Guest
What happens next
Anything goes
Part 1: team questions
Part 2: Questions for the audience
Quick round up and thanks by host
27

Thursday 10 May 2007
08:30-10:00 Poster viewing Hall 3
08:30-09:30 BHPR: Special Interest Groups
Rheumatoid Arthritis Hall 11
Convenor: Janet Cushnaghan
• Attenders and non-attenders at an education group - Jackie McDowell
• Update on splinting audit - Alexa Crook
• Is our current practice of administering I/A steroid to the knee meeting agreed standards? -
an audit - Wendy Pointer
Connective Tissue Disease Hall 8a
Convenor: Sue Brown
• Diagnosis and Treatment of Vasculitis - David G I Scott
• The Role of the Clinical Nurse Specialist in Vasculitis - Sue Brown
Osteoporosis Hall 8b
Convenor: Rachel Lewis
The Role of an Osteoporosis Practitioner at West Dorset Osteoporosis Services - Jane Raleigh
09:30-10:00 BHPR: AGM Hall 11
10:00-10:30 Tea/Coffee Hall 3
10:30-12:30 BSR: Myositis Hall 4
Chair: David Isenberg
• Myositis - The problems David Isenberg
The Bohan and Peter criteria for diagnosing myositis have lasted for 30 years. This talk will explain
that there are problems with each criterion and suggest that the time for a change may be upon us.
• Update on new methods of disease assessment Shabina Sultan
Rather belatedly an international effort has been going to optimise the assessment of patients with
myositis. An activity index (MITAX), a damage index (MYODAM) and health assessment (SF36)
will be reviewed.
• Immunopathology Ingrid Lundberg
In this presentation the potential role of the Type I Interferon system and the role of T cells in
myositis will be discussed in relation to clinical subsets and different autoantibody profiles.
• Imaging David L Scott
Imaging muscles, particularly with MRI and ultrasound, helps diagnose and assess myositis and help
in biopsying inflamed areas. Novel methods, like magnetic resonance spectroscopy that assess
metabolites like ATP, may move from research into general use.
• Update on therapy Ernest Choy
Treatment of myositis commonly involves the use of immunosuppressants although the efficacy of
these agents have not been proved in randomised control trials. While intravenous immunoglobulin
has been shown to be effective in dermatomyositis, its long-term benefit has not been studied. In
refractory patients, biologic agents such as tumour necrosis factor antagonists and rituximab are
promising but their benefit and toxicity will need to be studied in randomised control trials.
29

10:30-12:30 BSR: Autoinflammatory Disease, what is it, what do Rheumatologists need to know about it?
Hall 1
Chair: Patricia Woo
• Introduction, what do rheumatologists need to know about the innate immune system?
Paul Bowness
This talk will give an overview of the innate immune system for the non-immunologist and introduce
some of the cellular and molecular concepts involved in autoinflammatory diseases.
• Pathophysiology and treatment of tumor necrosis factor receptor-associated periodic syndrome
(TRAPS) Richard Powell
This talk will detail the pathogenic mechanisms invloved in the TNF receptor-associated periodic fever
syndrome, and outline current best treatments for a general audience.
• Other autoinflammatory diseases: current insights and prospects Joost Frenkel
The genes responsible for most hereditary fever syndromes have been identified. The encoded
proteins affected the inflammasome pathway. This is a mechanism that responds to pathogen
associated molecules in the cytoplasm with IL-1 mediated inflammation. IL-1 blockade has proven
highly effective in some of these disorders.
10:30-12:30 BSR/BHPR: Activity Monitoring in Musculoskeletal Conditions Hall 5
Chair: Ross Wilkie
• Introduction Lynne Goodacre
• Monitoring physical activity using motion sensors Jennifer Hootman
This presentation will present the current physical activity recommendations for the general public and
adults with arthritis and define the problem of inactivity among adults with arthritis. Motion sensors
may be a useful method to monitor activity levels among adults with arthritis, types of motion sensors
and factors related to choosing and using these devises with arthritis patients will be discussed.
• Movement analysis in arthritis assessment Jim Richards
This session will provide a critical overview of current tools for assessing movement and activity in
research and clinical practice.
• Qualitative approaches to assessing activity Lynne Goodacre
This presentation will explore the use of interviews, activity diaries and questionnaires in the
assessment and monitoring of levels of activity in clinical and research settings.
• Open discussion Lynne Goodacre & Jim Richards
10:30-12:30 BHPR: Current issues in Rheumatoid Arthritis Hall 11
Chair: Jacqueline Hill & Diana Finney
• Red Flags Chris Deighton
There are lots of "red flags" in RA. This talk will focus on complications of anti-TNF therapies
(particularly infections), and presentations of atlanto-axial subluxation.
• NSAIDs Jon Packham
Update on NSAID use in arthritis – risks, benefits and when to use them
• Current Issues from the therapist perspective Jane Hall
This presentation will review current approaches/therapies in the treatment of rheumatoid arthritis in
the context of the anti-TNF and guidelines era.
• Latest developments in podiatry Jim Woodburn
Opportunities aplenty! Exciting developments in clinical practice and policy, research and education
reveal podiatry as the burgeoning profession in rheumatology
• What’s new with biologics Susan Oliver
Biologic therapies provide an important treatment option for inflammatory arthritides.
This presentation will discuss licensed biologic therapies and outline the key issues that need to be
considered in the management of individuals treated with biologics. A brief overview of future biologic
therapies will also be outlined.
30

• What should we do in an annual review clinic Kate Gadsby
A number of authoritative guidelines have recommended that annual review should be established
for inflammatory arthritis patients. This talk considers the practicalities and content of annual
reviews.
10.30-12.30 BHPR: Joint examination in RA Hall 10
Chair: Sarah Ryan
Speaker: Kay Stevenson & Cath Thwaites
• What you need to know about clinical anatomy (quiz format)
• How to get the most out of taking a clinical history
• Top hints for joint examination
• How to interpret clinical findings
12:30-14:30 Lunch Hall 3
12:45-14:00 BSR AGM Hall 9
(Lunch will be available at the meeting)
14:30-16:30 Concurrent Oral Presentation of Abstracts
Novel Autoantibodies Hall 10
Chair: Rizgar Mageed
OP31 A p155/140 kDa cancer-associated autoantigen in adult dermatomyositis is a major
autoantigen target in juvenile dermatomyositis
J North 1 , H Gunawardena 2 , LR Wedderburn 3 , J Davidson 4 , Z Betteridge 1 , J Dunphy 1 , H Chinoy 5 ,
RG Cooper 5 , NJ McHugh 2 .
1
School for Health, University of Bath, Bath, United Kingdom; 2 Rheumatology, Royal National Hospital
for Rheumatic Diseases, Bath, United Kingdom; 3 Institute for Child Health, University College London,
London, United Kingdom; 4 Rheumatology, Royal Hospital for Sick Children, Glasgow, United Kingdom;
5
Rheumatic Disease Centre, Hope Hospital, Salford, United Kingdom
OP32 Young Investigator Award Winner: Anti-sumo E1: a novel autoantibody in
dermatomyositis directed against the small ubiquitin-like modifier activating enzyme
ZE Betteridge 1 , H Gunawardena 1,2 , J North 1 , J Slinn 3 , NJ McHugh 1,2 .
1
School for Health, University of Bath, Bath, United Kingdom; 2 Rheumatology, Royal National Hospital
for Rheumatic Diseases, Bath, United Kingdom; 3 Applied Sciences, University of the West of England,
Bristol, United Kingdom
OP33 Young Investigator Award Winner: Aberrant expression of B cell survival factors in
salivary gland’s malt lymphomas during sjogren’s syndrome
F Barone 1,6 , M Bombardieri 1 , J Spencer 2 , P Isaacson 3 , R Carsetti 4 , P Morgan 5 , S Challacombe 5 ,
G Valesini 6 , C Pitzalis 1 .
1
Rheumatology, GKT School of Medicine, London, United Kingdom; 2 Immunology, GKT School of
Medicine, London, United Kingdom; 3 Immunology, UCL, London, United Kingdom; 4 Immunology,
Ospedale Bambino Gesù, Rome, Italy; 5 Oral Pathology and Medicine, GKT School of Medicine, London,
United Kingdom; 6 Reumatologia, Università La Sapienza, Roma, Italy
31

OP34 Anti-Zo: a new autoantibody to phenylalanine-transfer RNA synthetase associated with
polymyositis and interstitial pneumonia
ZE Betteridge 1 , H Gunawardena 1,2 , J North 1 , J Slinn 3 , NJ McHugh 1,2 .
1
School for Health, University of Bath, Bath, United Kingdom; 2 Rheumatology, Royal National Hospital for
Rheumatic Diseases, Bath, United Kingdom; 3 Applied Sciences, University of the West of England,
Bristol, United Kingdom
OP35 The synovial fluid is a specific site of expression of citrullinated autoantigens in rheumatoid
arthritis
AJ Kinloch 1 , K Lundberg 1 , R Wait 1 , PJ Venables 1 .
1
Kennedy Institute of Rheumatology, Imperial College London, London, United Kingdom
OP36 Mapping of citrullinated α-enolase antibodies to an immunodominant epitope with high
sequence similarity to bacterial enolase
KE Lundberg 1 , A Kinloch 1 , HE Allison 2 , S Sriskandan 3 , DL Moyes 1 , PJ Venables 1 .
1
The Kennedy Institute of Rheumatology, Charing Cross Campus, Imperial College, London, United
Kingdom; 2 School of Biological Sciences, Division of Genomics and Molecular Microbiology, University of
Liverpool, Liverpool, United Kingdom; 3 Faculty of Medicine, Hammersmith Hospital, Imperial College,
London, United Kingdom
OP37 Arginine residues in human monoclonal antiphospholipid antibodies are important in
determining their ability to bind and affect the function of antigens relevant to the pathogenesis of
atherosclerosis in the antiphospholipid syndrome
I Giles 1 , A Lambrianides 1 , S O’Neill 1 , P Chen 2 , D Latchman 1 , D Isenberg 1 , A Rahman 1 .
1
Division of Medicine/Centre for Rheumatology Research & Medical Molecular Biology Unit, University
College London, London, United Kingdom; 2 Division of Medicine/Department of Rheumatology,
University College of Los Angeles, Los Angeles, CA, United States
OP38 Anti-cadriolipin antibodies are associated with early atherosclerosis in medical conditions
other than the antiphospholipid syndrome – coronary artery disease and rheumatoid arthritis
Y Sherer 1 , Y Shoenfeld 1 .
1
Center of Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel
Osteoarthritis Hall 4
Chair: Fraser Birrell
OP39 Accelerated disease in a surgical model of murine OA in mice lacking FGF-2
SL Chia 1 , J Inglis 1 , D Essex 2 , J Saklatvala 1 , TL Vincent 1 .
1
Department of Cell Signalling, Kennedy Institute of Rheumatology, London, United Kingdom;
2
Department of Histopathology, Charing Cross Hospital, London, United Kingdom
OP40 Fibronectin fragments induce aggrecan degradation in human cartilage and are increased
in osteoarthritic cartilage
N Sofat 1 , R Wait 1 , H Nagase 1 .
1
Matrix Biology, The Kennedy Institute of Rheumatology Division, Faculty of Medicine, Imperial College
London, London, United Kingdom
OP41 Occupation and patterns of radiographic knee osteoarthritis
RJ Lacey, E Thomas, RC Duncan, GM Peat.
1
Primary Care Musculoskeletal Research Centre, Keele University, Keele, Staffordshire, United Kingdom
32

OP42 Radiographic presentation of osteoarthritis of the thumb
M Marshall, KS Dziedzic, EE Nicholls, HL Myers, EM Hay.
1
Primary Care Musculoskeletal Research Centre, Keele Univeristy, Keele, Staffordshire, United Kingdom
OP43 A MRI study of the extent of “gold standard”-evaluated synovitis and its relationship to
pain in osteoarthritis of the knee
PG Conaghan 1 , LA Rhodes 2 , EMA Hensor 1 , C Thomas 1 , P Emery 1 , AJ Grainger 3 .
1
Academic Unit of Musculoskeletal Disease, University of Leeds, Chapel Allerton Hospital, Leeds,
Yorkshire, United Kingdom; 2 Academic Unit of Medical Physics, University of Leeds, Leeds, Yorkshire,
United Kingdom; 3 Department of Radiology, Chapel Allerton Hosptial, Leeds, Yorkshire, United Kingdom
OP44 Further evidence for the importance of ligaments and tendons in the phenotypic
expression of hand osteoarthritis – a combined high-resolution positron emission tomography
and high-resolution magnetic resonance imaging study
AL Tan 1 , ML Waller 2 , EM Hensor 1 , SF Tanner 3 , AP Jeavons 3 , P Emery 1 , D McGonagle 1 .
1
Academic Unit of Musculoskeletal Disease, Chapel Allerton Hospital, Leeds, United Kingdom;
2
Department of Medical Physics and Engineering, Leeds General Infirmary, Leeds, United Kingdom;
3
Academic Unit of Medical Physics, University of Leeds, Leeds, United Kingdom
OP45 Outcomes and methodology in genetic association studies of peripheral joint osteoarthritis
and spinal degenerative disease
JJ Ryder 1 , K Garrison 1 , F Song 1 , L Hooper 1 , J Skinner 1 , Y Loke 1 , AJ MacGregor 1 .
1
School of Medicine, Health Policy & Practice, University of East Anglia, Norwich, Norfolk, United
Kingdom
OP46 Severe knee osteoarthritis: a randomised controlled trial of acupuncture, physiotherapy
(supervised exercise), and standard management for patients awaiting knee replacement
MR Wyatt 1 , K Yein 2 , JTK Melton 3 , L Williamson 2 .
1
Physiotherapy, The Great Western Hospital, Swindon, Wiltshire, United Kingdom; 2 Rheumatology,
The Great Western Hospital, Swindon, Wiltshire, United Kingdom; 3 Orthopaedics, The Great Western
Hospital, Swindon, Wiltshire, United Kingdom
Advances in Therapy Hall 1
Chair: Peter Taylor
OP47 Abatacept (ABA) slows radiographic progression over 2 yrs in rheumatoid arthritis (RA)
patients (Pts) with an inadequate response to methotrexate (MTX): results from the long-term
extension (LTE) of the aim trial
R Westhovens 1 , C Peterfy 2 , G Vratsanos 3 , JC Becker 3 , R Aranda 3 , J Teng 3 , J Kremer 4 , HK Genant 5 .
1
Department of Rheumatology, University Hospitals, K.U Leuven, Leuven, Belgium; 2 Synarc Inc, San
Francisco, CA, United States; 3 Global Clinical Research, Immunology, Bristol-Myers Squibb, Princeton,
NJ, United States; 4 Center for Rheumatology, Albany, NY, United States; 5 UCSF/Synarc, San Francisco,
CA, United States
OP48 Benefit of switching to a second anti-TNF therapy on HAQ response in rheumatoid
arthritis patients with lack of response to their first anti-TNF therapy: results from the BSR
Biologics Register (BSRBR)
M Lunt 1 , KL Hyrich 1 , KD Watson 1 , WG Dixon 1 , DP Symmons 1 , BSR Biologics Register 1 .
1
arc Epidemiology Unit, University of Manchester, Manchester, United Kingdom
33

OP49 Audit of anti TNF treatment in Behçets disease
G Grundy 1 , RJ Moots 1 .
1
Academic Rheumatology Dept, Aintree Hospitals University Foundation Trust, Liverpool, United Kingdom
OP50 Effects of adverse publicity regarding NSAIDs and perceptions of cardiovascular and
gastrointestinal risk in patients with inflammatory arthritis
WA Holden 1 , J Joseph 2 , L Williamson 1 , D Berry 3 , E Price 1 .
1
Rheumatology, Great Western Hospital, Swindon, United Kingdom; 2 Rheumatology, Aretaeion Hospital,
Nicosia, Cyprus; 3 Psychology, University of Reading, Reading, United Kingdom
OP51 Predicting response to rituximab in RA: different effects of B cell depletion in blood
and synovium
S Dass, CH Burgoyne, AC Rawstron, EM Vital, RJ Reece, F Ponchel, P Emery.
1
Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom
OP52 Costs and benefits of etanercept followed by rituximab at different stages of the treatment
sequence in patients with rheumatoid arthritis
M Taylor 1 , P Trueman 1 , AV Reynolds 2 , P Conway 2 .
1
York Health Economics Consortium, University of York, York, United Kingdom; 2 Scientific Affairs, Wyeth
Pharmaceuticals, Maidenhead, Berkshire, United Kingdom
OP53 Rheumatoid arthritis, interstitial lung disease, mortality and anti-TNFα therapy: further
insights from the BSR Biologics Register (BSRBR)
WG Dixon 1 , KD Watson 1 , M Lunt 1 , KL Hyrich 1 , BSR Control Centre Consortium 1 , DP Symmons 1 , BSR
Biologics Register 1 .
1
arc Epidemiology Unit, University of Manchester, Manchester, United Kingdom
OP54 Radiographic efficacy of adalimumab in patients with psoriatic arthritis according to
demographics, baseline clinical status, methotrexate use, and clinical response: subanalysis
of adept
EHS Choy 1 , DD Gladman 2 , PJ Mease 3 , P Wordsworth 4 , CT Ritchlin 5 , H Wang 6 , EH Sasso 6 .
1
King’s College, London, United Kingdom; 2 University of Toronto, Toronto, ON, Canada; 3 Swedish Medical
Center, Seattle, WA, United Kingdom; 4 Nuffield Orthopaedic Centre, Oxford, United Kingdom; 5 University
of Rochester, Rochester, MN, United States; 6 Abbott, Abbott Park, IL, United States
Pathogenesis Hall 5
Chair: Karim Raza
OP55 Young Investigator Award Winner: Combination therapy with etanercept and sgp130
for rheumatoid arthritis is more effective than monotherapy
SM Carty 1 , MA Nowell 2 , SN Lauder 1 , RM Goodfellow 1 , SA Jones 2 , BD Williams 1 , AS Williams 1 .
1
Rheumatology, College of Medicine, Cardiff University, Cardiff, Glamorgan, United Kingdom;
2
Biochemistry and Immunology, College of Medicine, Cardiff University, Cardiff, Glamorgan,
United Kingdom
OP56 Production of the B cell chemo-attractant CXCL13 (BCA-1) by activated T cells in
rheumatoid synovitis
A Manzo 1 , B Vitolo 2 , M Uguccioni 3 , C Montecucco 2 , C Pitzalis 1 .
1
Rheumatology Department, King’s College London, London, United Kingdom; 2 Cattedra di Reumatologia,
Universita’ Degli Studi di Pavia, Pavia, Italy; 3 Institute for Research in Biomedicine, (I.R.B), Bellinzona,
Switzerland
34

OP57 The role of HLA-B27 interactions with natural killer receptors in the pathogenesis of
spondyloarthritis
SD Kollnberger 1 , AT Chan 1 , LY Chen 1 , C Wright 1 , K diGleris 1 , P Bowness 1 .
1
MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom
OP58 Mesenchymal stem cells repair capabilities are defectives in RA in relation with in vivo
exposure to inflammation
SL Field 1 , E Jones 1 , A English 1 , R Reece 1 , P Emery 1 , D McGonagle 1 , F Ponchel 1 .
1
Leeds Institute of Molecular Medicine, Leeds University, Leeds, United Kingdom
OP59 Epigenetic modification of the TNF promoter is associated with rheumatoid arthritis
IR Gowers 1 , GW Duff 1 , AG Wilson 1 .
1
School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, United Kingdom
OP60 The mechanisms of action of CD8+ T cells with regulatory phenotype and function
LB Jarvis, JC Goodall, JS Hill Gaston.
1
Medicine, University of Cambridge, Cambridge, Cambs, United Kingdom
OP61 Galectins differentially regulate inflammatory cytokine and chemokine production by
synovial fibroblasts in rheumatoid arthritis
A Filer 1 , E Trebilcock 1 , G Parsonage 1 , J Fitton 1 , SJ Curnow 1 , M Salmon 1 , G Rabinovich 2 , CD Buckley 1 .
1
Rheumatology Research Group, University of Birmingham, Birmingham, United Kingdom; 2 Division of
Immunogenetics, University of Buenos Aires, Buenos Aires, Argentina
OP62 Association of human genes mapping to chromosome 12p13, homologues of genes in
the oil induced arthritis 2 (Oia2) locus in rats, with susceptibility to RA
KBS Spreckley, S Eyre, J Worthington, A Barton.
1
ARC Epidemiology Department, University of Manchester, Manchester, Lancashire, United Kingdom
14:30-16:30 BHPR: Oral presentation of abstracts Hall 11
Chairs: Isabel Raiman and Jackie Hill
OP63 The impact of non-inflammatory musculoskeletal hand conditions in a community
dwelling population of older adults
K Dziedzic 1 , E Nicholls 1 , H Myers 1 , G Peat 1 , J Handy 1 , E Thomas 1 , L Wood 1 , M Marshall 1 , C Tyson 2 ,
EM Hay 1 .
1
Primary Care Musculoskeletal Research Centre, Keele University, Keele, Staffordshire, United
Kingdom; 2 North Staffordshire Combined Healthcare Trust, Stoke-on-Trent, Staffordshire, United
Kingdom
OP64 Patients’ understanding of the risks associated with their anti-TNF therapy is suboptimal
despite a dedicated educational programme
SJ Evans 1 , B Rhys-Dillon 1 , CA Ilsley 1 , S Siebert 1 , U Srinivasan 1 .
1
Rheumatology Department, Princess of Wales Hospital, Bridgend, Mid Glamorgan, United Kingdom
OP65 The 18-week delivery programme and its impact on rheumatology services – an audit
AP Malaviya 1 , S Wijesooriya 1 , EJ Timpson 2 , M Catling 2 , AK Osman 1 , J Palit 1 , RC Arora 1 , NST Gendi 1 .
1
Department of Rheumatology, Basildon and Thurrock University Hospitals NHS Trust, Basildon, Essex,
United Kingdom; 2 Outpatient Directorate, Basildon and Thurrock University Hospitals NHS Trust,
Basildon, Essex, United Kingdom
35

OP66 Physiotherapists views of exercise for knee pain in older adults: in line with current
recommendations?
MA Holden 1 , NE Foster 1 , EE Nicholls 1 , J Young 1 , M Doherty 2 , EM Hay 1 .
1
Primary Care Musculoskeletal Research Centre, Keele University, Keele, Staffordshire, United Kingdom;
2
Academic Rheumatology, Nottingham City Hospital, Nottingham, Nottinghamshire, United Kingdom
OP67 A new physical therapy care program for connective tissue disease
A Dean, N Felthouse, H Nutland, K Murfin, H Smith, A Holmes, S Arthanari, M Nisar.
1
Dept of Rheumatology, Queens Hospital Trust, Burton on Trent, Staffs, United Kingdom
OP68 A qualitative study exploring the impact of uncertainty for the lupus patient between onset
of symptoms and diagnosis
NM Waldron 1 , S Brown 1 .
1
Research and Clinical Effectiveness, Royal National Hospital for Rheumatic Diseases, Bath, Noth East
Somerset, United Kingdom
16:30-17:00 Tea/Coffee Hall 3
17:00-18:00 Heberden Round Hall 1
Elaine Hay
Chair: Andrew Bamji
Is it all in my mind, doctor?
This talk will explore the challenges of managing patients with chronic musculoskeletal problems -
particularly drawing on my clinical and research experience from primary care.
19:30 Social Event: Bhangra Nights
Onwards Shimla Pinks, 19.30-23.30hrs
An evening of Birmingham’s finest cuisine and entertainment, at one of their most famous restaurants!
Don’t miss out on the chance to enjoy drinks and dancing with colleagues and friends.
36

Friday 11 May 2007
08:30-10:00 Poster viewing Hall 3
10:00-11:00 State of the Art Lecture Hall 1
Niall Dickson, Chief Executive Kings Fund
Do Doctors have a Future?
10:00-11:00 BHPR: Research Initiatives Hall 11
Including BHPR Poster Prize, arc prize and NRAS
Chair: Sarah Ryan & Jackie McDowell
• The Educational Needs Assessment Tool Jackie Hill
The arthritis Educational Needs Assessment Tool (ENAT) has been developed to quickly assess
educational and informational needs of patients with arthritis. The development and testing of this
tool will be described and results regarding the patients’ perceptions of their needs will be provided.
• Levels of fatigue in diffuse and limited Systemic Sclerosis Naomi Reay , arc Silver Medal winner
This presentation reveals empirical evidence of fatigue levels in people with Systemic Sclerosis, and
proceeds to discuss a strategy for its clinical management.
• Assessment and models of rehabilitation for patients with musculoskeletal conditions
Ross Wilkie
This presentation will describe conceptual and empirical approaches to the application of the
International Classification of Functioning, Disability and Health (ICF) for the assessment and
rehabilitation of patients with musculoskeletal disorders.
• TBC NRAS winner
11:00-11:30 Tea/Coffee & Exhibition Close Hall 3
11:30-13:00 BSR: Economics: Rheumatology in the changing NHS Hall 1
Chair: Andrew Bamji
• Introduction: implications of the White Paper and MSS Andrew Bamji
• Rheumatology: the demographics of treatment John Murray, JMC Partners LLP
The NHS’s programme budgeting data are beginning to yield interesting insights into levels of
expenditure on different specialities and between different PCTs. Categories include
musculoskeletal problems, one of the biggest and most debilitating areas of morbidity – but is it
getting a fair crack of the whip?
• Secondary care: CATS and triage John Halsey
This talk will review the implications the Musculoskeletal Services Framework will have on
rheumatology service provision, and also consider the challenge presented by the imposition of
independent sector services.
• The interface: breaking the Chinese Wall Mike Shadforth
The NHS is currently driving to have patients seen “Closer to Home”. Stoke Rheumatologists have
been attempting to achieve this for 10 years and are now quite successful. Attaining credence with
commissioners was difficult, and not fully achieved until the remit for rheumatological provision was
relocated with a PCT. A strong multidisciplinary team at the interface has worked well. Neither
side accepted GPs taking over the work of rheumatologists.
• GP and secondary care partnerships Adam Bajkowski, President of PCR
An overview of the changing relationship between GP's and their secondary care colleagues as
they strive to treat the same patient.
• Can GPs go it alone? Donal Hynes, General practitioner, Bridgewater
Under Practice Based Commissioning, the delivery of rheumatology services will radically alter.
Rheumatologists need to take ownership of difficult decisions about severing their links with
hospitals or risk having their speciality disappear completely in the new economic realities.
• Questions and summing-up
37

11:30-12:30 BHPR: Professional Issues Hall 11
Chairs: Patricia Cornell & Lindsey Hawley
• Prescribing for AHPs Sheena Hennell
Non-medical prescribing for Allied Health professionals - a 2006/07 update.
• Enhancing Concordance Gareth Treharne
Concordance' is shared decision making about medications that moves beyond 'non-compliance'.
A history of research on medication taking in rheumatic disease will be presented along with questions
to be posed in future research and potential implications for education and practice in rheumatology.
• Educational Opportunities for AHPs Alison Hammond
New educational opportunities will be discussed as well as initial research evaluating the arc
Graduate Certificate in Rheumatology Practice.
11:30-12:30 Poster discussions
Epidemiology Hall 10
Chair: Deborah Symmons
305 Road traffic accidents do not predict the onset of widespread body pain
J McBeth 1 , B Nicholl 1 , GT Jones 2 , G Wynne-Jones 3 , NJ Wiles 4 .
1
Arthritis Research Campaign Epidemiology Unit, University of Manchester, Manchester, United Kingdom;
2
Aberdeen Research Collaboration (Epidemiology Group) Department of Public Health, University of
Aberdeen, Aberdeen, United Kingdom; 3 Primary Care Musculoskeletal Research Centre, Keele University,
Keele, United Kingdom; 4 Academic Unit of Psychiatry, Department of Community Based Medicine,
University of Bristol, Bristol, United Kingdom
308 Workplace monotony and musculoskeletal pain – understanding the mechanisms
GT Jones 1 , F Blyth 1,2 , M Mikkelsson 3 , P Knekt 4 , A Aromaa 4 , M Heliovaara 4 , GJ Macfarlane 1 .
1
Aberdeen Pain Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United
Kingdom; 2 School of Public Health, University of Sydney, Sydney, Australia; 3 Department of Rehabilitation,
The Rheumatism Foundation Hospital, Heinola, Finland; 4 National Public Health Institute, Helsinki, Finland
302 The presentation of new regional musculoskeletal disorders to primary care
K Jordan 1 , P Croft 1 .
1
Primary Care Musculoskeletal Research Centre, Keele University, Newcastle, Staffs, United Kingdom
301 How accurate are diagnoses for rheumatoid arthritis and juvenile idiopathic arthritis in the
general practice research database?
SL Thomas 1 , CJ Edwards 2 , L Smeeth 1 , C Cooper 3 , AJ Hall 1 .
1
Department of Epidemiology and Public Health, London School of Hygiene & Tropical Medicine, London,
United Kingdom; 2 Department of Rheumatology, Southampton General Hospital, Southampton, United
Kingdom; 3 MRC Epidemiology Resource Centre, University of Southampton, Southampton, United
Kingdom
310 Differences in cardiovascular risk factor profiles between patients with and without
rheumatoid arthritis
SR Brady 1 , D Liew 1 , B deCourten 2 , CM Reid 1,2 .
1
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia;
2
Baker Heart Research Institute, Melbourne, Victoria, Australia
38

312 How common is chronic renal disease in patients attending rheumatology
outpatient clinics?
A Hill 1 , R Thomson 1 , JP Traynor 2 , G Roberts 3 , J Hunter 3 .
1
Medical School, University of Glasgow, Glasgow, United Kingdom; 2 Department of Renal Medicine,
Western Infirmary, Glasgow, United Kingdom; 3 Department of Rheumatology, Gartnavel General
Hospital, Glasgow, United Kingdom
RA-Clinical Hall 5
Chair: Peter Dawes
193 Audit of smoking and attitude to smoking cessation in rheumatoid arthritis
ND McKay, J Hamilton, V Saravanan, C Kelly.
1
Rheumatology, Queen Elizabeth Hospital, Gateshead, Tyne and Wear, United Kingdom
194 Smoking causes significant increases of basal metabolic rate in patients with
rheumatoid arthritis
GS Metsios, A Stavropoulos Kalinoglou, K Douglas, AM Nevill, Y Koutedakis, GD Kitas.
1
Rheumatology, Russell’s Hall Hospital, Dudley Group of Hospitals NHS Trust, Dudley, West Midlands,
United Kingdom; 2 School of Sports, Performing Arts and Leisure, University of Wolverhampton,
Wolverhampton, West Midlands, United Kingdom
229 Are we focusing the use of anti cyclical citrulinated peptide antibodies tests in patients
with rheumatoid arthritis?
ECS Wong 1 , K Murphy 2 , A Bradlow 2 .
1
Rheumatology Department, Nuffield Orthopaedic Centre, Oxford, Oxfordshire, United Kingdom;
2
Rheumatology Department, Royal Berkshire Hospital, Reading, Berkshire, United Kingdom
185 Antibodies to citrullinated vimentin are a specific and sensitive marker for the diagnosis
of rheumatoid arthritis
H Poulsom 1 , PJ Charles 1,2 .
1
Immunology, Hammermsith Hospitals NHS Trust, London, United Kingdom; 2 Kennedy Institute of
Rheumatology, Imperial College, London, United Kingdom
201 Anti-cyclic citrullinated peptide (Anti-CCP) antibodies as indicators of disease severity
in rheumatoid arthritis
A Rezaei 1 , G Firth 1 , K Walker-Bone 2 .
1
Clinical Biochemistry, Brighton & Sussex University Hospitals NHS Trust, Brighton, East Sussex, United
Kingdom; 2 Rheumatology, Brighton & Sussex Medical School, Brighton, East Sussex, United Kingdom
191 Predictors of further radiological damage in patients who have erosive disease after five
years of inflammatory polyarthritis
M Bukhari, H Naseem, A Barton, D Bunne, DPM Symmons.
1
ARC Epidemiology Unit, University of Manchester, Manchester, United Kingdom
Soft Tissue Hall 4
Chair: Nick Shenker
316 Sleep disturbance and its relationship to cytokines in patients with
fibromyalgia syndrome
MA Stanislavchuk 1 , SV Kolyadenko 1 .
1
Rheumatology, National Medical University, Vinnytsya, Ukraine
39

317 Magnesium deficiency and sleep-disorders in patients with fibromyalgia
MA Stanislavchuk 1 , VM Khomenko 1 .
1
Rheumatology, National Medical University, Vinnytsya, Ukraine
319 Can simple clinical tests replace electromyography in diagnosis of carpal tunnel syndrome?
L Das 1 , AS Sayegh 1 , SO’N Daunt 1 .
1
Rheumatology, Colchester General Hospital, Essex Rivers NHS Trust, Essex, United Kingdom
313 Sensitivity to change of the carpal tunnel syndrome global severity scoring system:
A prospective study
Y El Miedany 1 , S Ashour 2 , S Youssef 1 , A Mehanna 3 , M El Gaafary 4 .
1
Rheumatology and Rehabilitation, Ain Shams University, Cairo, Egypt; 2 Neurology, Ain Shams
321 The pain burden of participants in pragmatic trials for regional musculoskeletal conditions
J Barber, M Lewis, S Mottram, EM Hay.
1
Primary Care Musculoskeletal Research Centre, Keele University, Keele, Staffordshire, United Kingdom
323 The relief of chronic low back pain immediately after one session of low level laser
acupuncture therapy: An evaluation of the effect of prayer
DA Houssien.
1
Rheumatology, Dr Dhiya for Rheumatism, Jeddah, Saudi Arabia
Health Service Research Hall 9
Chair: Peter Croft
244 Views and goals of doctors and nurses in their consultations with patients who live with
rheuamtoid arthritis
H Lempp 1 , DL Scott 2 , GH Kingsley 3 .
1
Academic Department of Rheumatology, King’s College London School of Medicine, London, United
Kingdom; 2 Department of Rheumatology, King’s College London NHS Trust, London, United Kingdom;
3
Department of Rheumatology, University Hospital Lewisham NHS Trust, London, United Kingdom
272 Keen to live until i die: patients perspectives of the impact of anti TNF therapy on their
quality of life
KS Mills 1 , AAM Nicol 2 , M Somerville 1 , N Healey 2 , RD Smith 2 , DGI Scott 1 .
1
Rheumatology Department, Norfolk and Norwich University Hospital, Norwich, Norfolk, United
Kingdom; 2 School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, Norfolk,
United Kingdom
283 Changes in distress and health beliefs in people with chronic low back pain following
different kinds of physiotherapy
DJ Critchley 1 , CJ Dore 2 , S Noonan 3 , RH Jones 4 , MV Hurley 1 .
1
Academic Department of Physiotherapy, King’s College London, London, United Kingdom; 2 Clinical Trials
Unit, Medical Research Council, London, United Kingdom; 3 Physiotherapy Department, Guy’s and St
Thomas’ Hospitals, London, United Kingdom; 4 School of Medicine, King’s College London, London,
United Kingdom
40

257 Documentation of anti-TNF therapy in primary care health records
EM Wise 1,2,3 , C Burdon 4 , K Nicholl 1 , NS Booth 5 , J Dickson 6 , LJ Kay 1,3 .
1
Musculoskeletal Unit, Freeman Hospital, Newcastle upon Tyne, United Kingdom; 2 Belmont Surgery,
Durham, County Durham, United Kingdom; 3 Musculoskeletal Research Group, Newcastle University,
Newcastle upon Tyne, United Kingdom; 4 Roseworth Avenue Surgery, Gosforth, Newcastle upon Tyne,
United Kingdom; 5 Primary Healthcare, Specialist Group, British Computer Society, United Kingdom;
6
Primary Care, Rheumatology Society, Northallerton, United Kingdom
266 A primary care audit of the ARMA standards of care in osteoarthritis
L Davies 1 , JP Halsey 2 , M Bukhari 2 .
1
Rosebank Surgery, Morecambe Bay PCT, Lancaster, Lancashire, United Kingdom; 2 Rheumatology,
Royal Lancaster Infirmary, Lancaster, Lancashire, United Kingdom
246 Vaccinate your patients – an audit from primary care
RA Watts 1 , S Rudland 2 .
1
Department of Rheumatology, Ipswich Hospital NHS Trust, Ipswich, Suffolk, United Kingdom;
2
StowHealth, Stowmarket, Suffolk, United Kingdom
12:30-13:30 Lunch provided on departure Registration Area
13:15-15:15 BSR Special Interest Groups
Foot and Ankle Hall 10
Convenor: Anthony Redmond
• Welcome and introduction to the SIG. Overview of activities this year and upcoming projects –
Anthony Redmond
• Footwear for people with RA: factors influencing success - TBC
• Consultation on the standards of care for musculoskeletal foot heath services project -
Penny Renwick, Steering Group Chair and Anthony Redmond, Project Lead.
• The impact of the foot in multiple painful joint presentations -
Anne- Maree Keenan, University of Leeds
• Ultrasound and pressure findings in the MTP joints in RA -
Cathy Bowen, University of Southampton.
• Close
Heritable Disorders of Connective Tissue Hall 7a
Convenors: Rodney Graham and Howard Bird
Hypermobility Clinics – Who Needs Them?
Towards a National Strategy for Care Reports from the clinics:
• Glasgow - William Ferrell
Leeds - Howard Bird
UCH - Alan Hakim
Great Ormond Street - Nathan Hasson
• Contributions from representatives of patient self-help groups
• Discussion
• Formulation of SIG Policy on Patient Care
41

Osteoarthritis Hall 5
Convenor: Fraser Birrell
• ARMA Standards of Care OA Audit Update - Fraser Birrell
• Hand OA in the Community: From Park Bench to Bedside - Krysia Dziedzic
• Update on OA Genetics - John Loughlin
• Lessons from the NIH OA Initiative - Virginia Byers Kraus
• Close
Systemic Lupus Erythematosus Hall 11
Convenors: Bridget Griffiths and Ian Bruce
• Physical fitness, cardiovascular risk and fatigue in SLE - Samuele Marcora and Francesco Casanova
• Microarrays in SLE - David Jayne
• The imaging of cerebral lupus - John Axford
• Discussion of current multi centre studies in SLE
Paediatrics Hall 7b
Convenors: Alison Jordan and Liza McCann
Bridging the Gap between Paediatric and Adult Rheumatology Services
• Welcome and Introduction - Alison Jordan
• Case Based Discussion - Liza McCann
• Developing Services for Adolescents - Janet McDonagh
• Setting Up Services for Young People, Ideas and Practicalities - Andrea Myers & Elizabeth Rankin
• Adolescent Curriculum And National Training Initiatives - Richard Hull
• Research Opportunities - Michael Beresford
Polymyalgia Rheumatica and Giant Cell Arteritis Hall 8b
Conveners: Bhaskar Dasgupta
Programme:
• Classification criteria for PMR: prospective study - Bhaskar Dasgupta, Southend University Hospital
• BSR draft guidelines for PMR & GCA - Nada Hassan, Mid-Essex Hospital, Chelmsford
• PMR/GCA Support group - Jennifer Nott, Bury St Edmonds
• New Therapies in PMR & GCA - Speaker TBA
Scleroderma Hall 9
Convenors: Carol M. Black and Christopher P. Denton
Therapeutic goals in scleroderma: who sets the standards?
• French connection – renal crisis frequency and outcome – a national survey - Luc Mouthon
• Goal-directed or evidence-based therapy for pulmonary arterial hypertension? - Gerry Coghlan
• Quality of life assessment in pulmonary arterial hypertension – CAMPHOR in practice -
Natalie Doughty
• Quality of life assessment in scleroderma – disease- specific tool - Naomi Reay
42

POSTER VIEWING 1 – WEDNESDAY
PAEDIATRIC AND ADOLESCENT RHEUMATOLOGY
1 EFFECT OF PRESENTING SYMPTOMS ON DELAY TO PAEDIATRIC RHEUMATOLOGY SPECIALIST
CARE IN CHILDREN SUSPECTED OF HAVING INFLAMMATORY ARTHRITIS: RESULTS FROM THE
CHILDHOOD ARTHRITIS PROSPECTIVE STUDY (CAPS)
N Adib 1 , J Thornton 1 , K Hyrich 1 , M Lunt 1 , H Foster 2 , J Davidson 3 , J Gardner-Medwin 3 , E Baildam 4 , L Wedderburn 5 ,
W Thompson 1 .
1
arc Epidemiology Unit, University of Manchester, Manchester, United Kingdom; 2 Department of Rheumatology,
University of Newcastle upon Tyne, Newcastle, United Kingdom; 3 Department of Child Health, Royal Hospital for
Sick Children, Glasgow, United Kingdom; 4 Department of Rheumatology, Royal Liverpool Children’s Hospital,
Liverpool, United Kingdom; 5 Institute of Child Health, University College London, London, United Kingdom
2 ADALIMUMAB (HUMIRA®) TREATMENT LEADS TO LONG-TERM SAFETY AND EFFICACY IN
CHILDREN WITH JUVENILE RHEUMATOID ARTHRITIS (JRA): 48-WEEK RESULTS
N Ruperto 1 , DJ Lovell 2 , L Jung 2 , A Reiff 3 , D Nemcova 1 , K Jarosova 1 , A Prieur 1 , C Sandborg 2 , J Rovensky 1 ,
J Bohnsack 2 , K Minden 1 , LW Weiner 2 , R Vehe 2 , G Horneff 1 , J Medich 4 , R Carcereri 5 , M McIlraith 5 , EH Giannini 2 ,
A Martini 1 .
1
PRINTO-IRCCS G Gaslini, Genova, Italy; 2 PRCSG, Cincinnati, OH, United States; 3 Children’s Hospital of Los
Angeles, Los Angeles, CA, United States; 4 Abbott, Parsippany, NJ, United States; 5 Abbott, Ludwigshafen,
Germany
3 CLINICAL IMPLICATION OF ANTI CCP ANTIBODIES IN JIA
R Gupta 1 , B Vaidya 1 , MM Thabah 1 , S Gupta 1 , SK Kabra 2 , R Lodha 2 .
1
Medicine, All India Institute of Medical Sciences, New Delhi, India; 2 Pediatrics, All India Institute of Medical
Sciences, New Delhi, India
4 INFLUENCE OF DISEASE-RELATED FACTORS ON BMD IN MEN AND WOMEN WITH JUVENILE
IDIOPATHIC ARTHRITIS (JIA)
J Thornton 1 , SR Pye 1 , H Foster 2 , D Rawlings 2 , RM Francis 2 , N Kumar 2 , A Myers 2 , DPM Symmons 1 , DM Ashcroft 3 ,
TW O’Neill 1 .
1
Arthritis Research Campaign Epidemiology Unit, University of Manchester, Manchester, United Kingdom;
2
Department of Rheumatology, Medical School, Newcastle upon Tyne, United Kingdom; 3 School of Pharmacy
and Pharmaceutical Sciences, University of Manchester, Manchester, United Kingdom
RHEUMATOID ARTHRITIS - TREATMENT
5 DOES CURRENT CONTROL OF RHEUMATOID ARTHRITIS INFLUENCE RHEUMATOID ARTHRITIS
PATIENTS’ ATTITUDES TO DMARD TREATMENT BASED ON KNOWLEDGE OF POTENTIAL SIDE
EFFECTS?
GH George.
1
Department of Rheumatology, Medway Maritime Hospital, Gillingham, Kent, United Kingdom
6 PATIENTS WITH RHEUMATOID ARTHRITIS DO NOT REMEMBER WHY THEIR DRUGS ARE STOPPED
N Kumar, NJ Marshall, PN Platt, DJ Walker.
1
Musculoskeletal Unit, Freeman Hospital, Newcastle-upon-Tyne, United Kingdom
43

7 THE INFLUENCE OF INDIVIDUAL DAS28 COMPONENTS ON OVERALL DAS28 RESPONSE TO
ANTI-TNF THERAPY IN RHEUMATOID ARTHRITIS
PP Reynolds 1 , S Patel.
1
Rheumatology, St. George’s Hospital, London, United Kingdom; 2 Rheumatology, St. Helier Hospital,
Carshalton, United Kingdom
8 GALACTOSYLATION LEVELS OF TOTAL SERUM GLYCOPROTEINS AS BIOMARKERS OF RHEUMATOID
ARTHRITIS
A Alavi 1 , OP Fraser, T Tarelli 2 , JS Axford.
1
The Sir Joseph Hotung Centre for Musculoskeletal Diseases, St George’s University of London, London,
United Kingdom; 2 Medical Biomics Centre, St George’s University of London, London, United Kingdom
9 A CASE OF SARCOIDOSIS FOLLOWING ETANERCEPT TREATMENT FOR RHEUMATOID ARTHRITIS
AV Kudrin 1 , A Ginawi 1 , ER Chilvers 2 , BL Hazelman 1 , AJK Ostor 1 .
1
Rheumatology, Addenbrooke’s Hospital, Cambridge, United Kingdom; 2 Respiratory Medicine, Addenbrooke’s
Hospital, Cambridge, United Kingdom
10 PATIENTS TAKING ANTI-TNF MEDICATION REPORT MORE FOOT COMPLAINTS BUT RECEIVE LESS
FOOT CARE
S Otter 1 , K Lucas 1 , K Springett 2 , A Young 3 , K Davies 4 , K Walker-Bone 4 .
1
School of Health Professions, University of Brighton, Eastbourne, East Sussex, United Kingdom; 2 School of Health
Professions, Canterbury Christ Church University, Canterbury, Kent, United Kingdom; 3 Rheumatology Dept, North
West Herts NHS Trust, St Albans, Hertfordshire, United Kingdom; 4 Brighton & Sussex Medical School, Brighton,
East Sussex, United Kingdom
11 CLINICAL RESPONSE TO METHOTREXATE CAN BE PREDICTED BY AN IN VITRO CYTOKINE
SUPPRESSION ASSAY
N Haroon 1 , R Srivastava 1 , R Misra 1 , A Aggarwal 1 .
1
Department of Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh,
India
12 SWITCHING ANTI-TNF AGENTS IS EFFECTIVE IN MOST RA PATIENTS: METHOTREXATE
DETERMINES LIKELIHOOD OF SUCCESS
LA Appiah 1 , IC Reading 2 , S Bennett 1 , C Summerfield 1 , NK Arden 1,2 , CJ Edwards 1 .
1
Rheumatology Department, Southampton University Hospital Trust, Southampton, Hampshire, United Kingdom;
2
MRC Epidemiology Resource Centres, Southampton University, Southampton, United Kingdom
13 RITUXIMAB THERAPY IN PATIENTS WITH RESISTANT RHEUMATOID ARTHRITIS
A Masding 1 , RN Jois 1 , M Somerville 1 , K Gaffney 1 , DGI Scott 1 .
1
Rheumatology, Norfolk and Norwich University Hospital, Norwich, Norfolk, United Kingdom
14 THE NORWICH EXPERIENCE OF LEFLUNOMIDE IN CLINICAL PRACTICE
C Ellis 1 , A Brooksby 1 , T Marshall 1 .
1
Department of Rheumatology, Norfolk and Norwich Universtity NHS Trust, Norwich, United Kingdom
15 LEFLUNOMIDE AND METHOTREXATE – FIVE YEARS ON AND STILL GOING STRONG
DA Collins 1 , E Tattersall 1 , EJ Price 1 , L Williamson 1 .
1
Department of Rheumatology, Great Western Hospital, Swindon, Wiltshire, United Kingdom
44

16 OUTCOME EXPECTANCY AND SELF-REPORTED ADHERENCE TO STATIC SPLINTING IN EARLY
RHEUMATOID ARTHRITIS
J Adams 1 , J Burridge 1 , M Mullee 2 , A Hammond 3 , C Cooper 4 .
1
School of Health Professions and Rehabilitation Sciences, University of Southampton, Southampton, Hants,
United Kingdom; 2 Research and Development Support Unit, Southampton University Hospital Trust,
Southampton, Hants, United Kingdom; 3 School of Health Professions, University of Brighton, Brighton, Sussex,
United Kingdom; 4 Medical Research Council, University of Southampton, Southampton, Hants, United Kingdom
17 REMISSION AND MAJOR CLINICAL RESPONSE IN ACTIVE RHEUMATOID ARTHRITIS (RA)
PATIENTS AFTER ADALIMUMAB (HUMIRA®) TREATMENT
GM Burmester 1 , P Wordsworth 2 , F McKenna 3 , GF Farraccioli 4 , R-M Flipo 5 , S Kary 6 , H Kupper 6 .
1
Charité – University Medicine Berlin, Berlin, Germany; 2 Nuffield Orthopaedic Centre, Oxford, United Kingdom;
3
Trafford General Hospital, Manchester, United Kingdom; 4 Catholic University of Rome, Rome, Italy; 5 University
Hospital, Lille, France; 6 Abbott GmbH & Co. KG, Ludwigshafen, Germany
18 DO PATIENTS WITH EARLY RHEUMATOID ARTHRITIS WHO DISCONTINUE METHOTREXATE
AFTER 6 MONTHS OF THERAPY EXPERIENCE INCREASED RADIOGRAPHIC PROGRESSION? —
A SUBANALYSIS OF PREMIER
P Emery 1 , EC Keystone 2 , M Genovese 3 , RF van Vollenhoven 4 , FC Breedveld 5 , EH Sasso 6 , K Patra 7 .
1
University of Leeds, Leeds, United Kingdom; 2 Mt. Sinai Hospital, Toronto, ON, Canada; 3 Stanford University
Medical Center, Palo Alto, CA, United States; 4 Karolinska University Hospital, Stockholm, Sweden; 5 Leiden
University Medical Center, Leiden, Netherlands; 6 Abbott, Abbott Park, IL, United States; 7 Abbott, Parsippany,
NJ, United States
19 ONCE OR TWICE A WEEK – WHICH IS BETTER?
S Bawa 1 , J Hall 1 , C Bufton 1 , S Edmonds 1 , M Webley 1 .
1
Department of Rheumatology, Stoke Mandeville Hospital, Aylesbury, Buckinghamshire, United Kingdom
20 LACK OF RESPONSE TO FIRST ANTI-TNFα AGENT SHOULD NOT PRECLUDE ALTERNATIVE
ANTI-TNFα THERAPY
J Pringle, A Stirling, MM Gordon.
1
Department of Rheumatology, Gartnavel General Hospital, Glasgow, United Kingdom
21 COMPARATIVE SYSTEMATIC REVIEW OF TNF-INHIBITORS AND INTENSIVE DMARD REGIMENS IN
RA SUGGESTS SIMILAR EFFICACY
GH Kingsley 1,2 , A Saha 1,3 , EH Choy 1,3 , DL Scott 1,3 .
1
Department of Rheumatology, Kings College London School of Medicine, London, United Kingdom;
2
Department of Rheumatology, University Hospital Lewisham, London, United Kingdom; 3 Department of
Rheumatology, Kings College Hospital, London, United Kingdom
22 SECONDARY FAILURE OF ADALIMUMAB (HUMIRA) IN RHEUMATOID ARTHRITIS PATIENTS
C De Silva, B Mason, B Kirkham.
1
Rheumatology Department, Guys and St Thomas’ Foundation Hospital, London, United Kingdom
23 DOES BURSITIS OF THE FOREFOOT IMPROVE IN PATIENTS WITH RHEUMATOID ARTHRITIS ON
ANTI-TNF-α THERAPY?
CJ Bowen 1 , K Dewbury 3 , M Sampson 3 , S Sawyer 2 , SP Bennet 2 , J Burridge 1 , CJ Edwards 2 , NK Arden 4 .
1
School of Health Professions and Rehabilitation Sciences, University of Southampton, Southampton,
Hampshire, United Kingdom; 2 Department of Rheumatology, Southampton University Hospitals NHS Trust,
Southampton, Hampshire, United Kingdom; 3 Ultrasound Department, Department of Radiology, Southampton
University Hospitals NHS Trust, Southampton, Hampshire, United Kingdom; 4 MRC Epidemiology Resource
Centre, University of Southampton, Southampton, Hampshire, United Kingdom
45

24 DOES SMOKING PREDICT POOR RESPONSE TO ANTI-TNF THERAPY FOR RHEUMATOID ARTHRITIS?
A Moorthy 1 , J Fisher 1 , A Duncan 1 , J Taylor 1 .
1
Department of Rheumatology, Northampton General Hospital, Northampton, Northamptanshire, United Kingdom
25 LOCAL EXPERIENCE OF SWITCHING ANTI-TNFα TREATMENTS FOR RHEUMATOID ARTHRTIS
SW Smale 1 , N Amos 1 , GL Morgans 1 , KE Lewis 1 , JP Camilleri 1 .
1
Rheumatology, University Hospital of Wales, Cardiff, United Kingdom
26 PARENTERAL METHOTREXATE IN ACTIVE RHEUMATOID ARTHRITIS: A PREREQUISITE FOR USE OF
BIOLOGIC AGENTS?
J Ward, V Ong, J Hibbitt, A Steuer.
1
Department of Rheumatology, Wexham Park Hospital, Slough, Berkshire, United Kingdom
27 WHAT PROPORTION OF PATIENTS IN A ROUTINE CLINIC FOR RHEUMATOID ARTHRITIS FULFIL THE
NICE CRITERIA FOR ANTI-TNF BIOLOGIC THERAPY?
I Atukorala 1 , T Ding 1 , J Carter 1 , P Bowness 1 , J David 1 , R Luqmani 1 , B Wordsworth 1 .
1
Department of Rheumatology, Nuffield Orthopaedic Centre, Headington, Oxford, United Kingdom
28 EFFICACY OF SWITCHING ANTI-TNF THERAPY AFTER INITIAL TREATMENT FAILURE IN 218 RA
PATIENTS
RI Amarasena 1 , S Brailsford 1 , P Jobanputra 1 , R Jubb 1 , E Rankin 1 , SJ Bowman 1 .
1
Rheumatology, Selly Oak Hospital,University Hospital Birmingham NHS Foundation Trust, Birmingham,
United Kingdom
29 SWITCHING FROM ORAL TO SELF ADMINISTERED SUBCUTANEOUS (SC) METHOTREXATE IN
UNCONTROLLED RHEUMATOID ARTHRITIS (RA) IS FEASIBLE AND EFFECTIVE: AN OBSERVATIONAL
STUDY IN AN OUTPATIENT, DISTRICT GENERAL HOSPITAL SETTING
WD Pointer, PL Williams.
1
Department of Rheumatology, Medway Maritime Hospital, Gillingham, Kent, United Kingdom
30 INCIDENCE OF CYTOPOENIAS WITH ANTI-TNFα THERAPY
R Yazdani 1 , H Simpson, VV Kaushik.
1
Rheumatology, Lincoln County Hospital, Lincoln, Lincolnshire, United Kingdom
31 CAN GOAL ORIENTED THERAPY FOR RHEUMATOID ARTHRITIS IMPROVE FUNCTIONAL OUTCOME?
NJ Gullick, G Panayi, T Gibson, S Oakley, B Mason, A Vincent, B Kirkham.
1
Department of Rheumatology, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom
32 REDUCING AZATHIOPRINE DOSE ACCORDING TO THIOPURINE METHYLTRANSFERASE ACTIVITY;
ARE SIDE-EFFECTS REDUCED OR IS EFFICACY JUST COMPROMISED?
SE Medley 1 , K Walker-Bone 2 .
1
Rheumatology, Princess Royal University Hospital, Farnborough, Kent, United Kingdom; 2 Rheumatology, Brighton
and Sussex Medical School, Brighton, East Sussex, United Kingdom
33 THE USE OF INTRA-ARTICULAR AND INTRA-MUSCULAR STEROID IN PATIENTS ATTENDING THE
RHEUMATOLOGY DEPARTMENT, STOBHILL HOSPITAL, GLASGOW
CD Campbell, H Wilson, A McEntegart, N Cheshire, D Baillie, D Moss, E McIvor.
1
Rheumatology Department, Stobhill Hospital, Glasgow, United Kingdom
46

34 TOLERABILITY OF METHOTREXATE AND LEFLUNOMIDE COMBINATION THERAPY IN ROUTINE
CLINICAL PRACTICE: RESULTS OF A FOUR-CENTRE STUDY
A Kaul 1 , D O’Reilly 2 , RK Slack 2 , D Collins 3 , E Tattersall 3 , O Duke 4 , J Walmsley 4 , PDW Kiely 1 .
1
Rheumatology, St. George’s NHS Trust, Tooting, London, United Kingdom; 2 Rheumatology, West Suffolk
Hospital, Bury St. Edmonds, Suffolk, United Kingdom; 3 Rheumatology, Great Western Hospital, Swindon,
Wiltshire, United Kingdom; 4 Rheumatology, Epsom and St. Helier NHS Trust, Carshalton, Surrey, United
Kingdom
35 METHOTREXATE FAILURE IN RHEUMATOID ARTHRITIS
CB Mukhtyar, T Marfina, S Krishnaraj, S Bawa, C Bufton, J Hall, M Webley, S Edmonds.
1
Department of Rheumatology, Stoke Mandeville Hospital, Mandeville Road, United Kingdom
36 DIFFERENT EFFECTS OF TNF BLOCKADE BY INFLIXIMAB AND ETANERCEPT ON NALP3 AND
INFLAMMASOME REGULATORS IN RHEUMATOID ARTHRITIS PATIENTS
R Mathews 1 , S Churchman 1 , L Church 1 , L Coulthard 1 , L Dickie 1 , S Nizam 2 , D Bryer 2 , B Saleem 2 , P Emery 2 ,
M McDermott 1 .
1
Rheumatology, Leeds Institute of Molecular Medicine, St James University Hospital, Leeds, United Kingdom;
2
Academic Unit of Musculoskeletal Disease, Chapel Allerton Hospital, Leeds, West Yorkshire, United Kingdom
37 CAN CHANGES ON ALCOHOL CONSUMPTION TO THE BSR GUIDELINES FOR LEFLUNOMIDE AND
METHOTREXATE BE JUSTIFIED?
S Rajakulendran 1 , D Allen 1 , C Deighton 1 .
1
Department of Rheumatology, Derbyshire Royal Infirmary, Derby, United Kingdom
38 A COUGH REDUCES THE PAIN OF A STEROID INJECTION
NG Shenker.
1
Rheumatology, Barts and The London (Mile End), London, United Kingdom
39 RESPONSE TO JOINT INJECTION AND SMOKING IN RHEUMATIC DISEASES
J Hoyle 1 , D Baxter 1 , J Hunter 1 .
1
Rheumatology Department, Gartnavel General Hospital, Glasgow, Scotland, United Kingdom
40 AUDIT OF CHANGING ANTI-TNFα IN PATIENTS WITH RHEUMATOID ARTHRITIS (RA) – A FIVE
YEAR EXPERIENCE (2001-2006)
A Abhishek 1 , J Berrington 1 , J Mc Hale 1 .
1
Department of Rheumatology, City Hospital Nottingham, Nottingham, United Kingdom
41 MUSCULOSKELETAL ULTRASOUND GUIDED JOINT INJECTIONS ARE SIGNIFICANTLY MORE
ACCURATE THAN CLINICAL EXAMINATION GUIDED JOINT INJECTIONS
JR Cunnington 1,2 , PN Platt 2 , G Hide 2 , DJ Kane 1 .
1
School of Clinical Medical Sciences (Dept Rheumatology), Newcastle University, Newcastle upon Tyne,
Tyne and Wear, United Kingdom; 2 Rheumatology, Freeman Hospital, Newcastle upon Tyne, Tyne and Wear,
United Kingdom
42 FACTORS INFLUENCING DMARD PRESCRIPTION IN EARLY RA
SM Rachapalli 1 , C Mayes 2 , D Walsh 2 , A Young 2 , PD Kiely 2,3 , EH Choy 1,2 .
1
Rheumatology, King’s College Hospital, London, United Kingdom; 2 Early Rheumatoid Arthritis Network (ERAN),
UK, United Kingdom; 3 Rheumatology, St George’s Hospital, London, United Kingdom
47

43 PATTERNS OF DMARD AND CORTICOSTEROID USE IN NEWLY DIAGNOSED RA PATIENTS ENROLLED
IN THE EARLY RHEUMATOID ARTHRITIS NETWORK (ERAN) DATABASE
PDW Kiely, CA Mayes, A Young, Participating ERAN Centers.
1
The Early Rheumatoid Arthritis Network, St Albans City Hospital, St Albans, Herts, United Kingdom
44 HOW WELL DO WE TREAT PATIENTS WITH RA? TOWARDS BENCHMARKING IN CLINICAL PRACTICE
PW Thompson, SCM Richards, J Taylor, P Cornell.
1
Rheumatology Unit, Poole Hospital NHS Trust, Poole, Dorset, United Kingdom
45 DOES DEPRESSION IN RHEUMATOID ARTHRITIS EFFECT THE EFFICACY OR SIDE EFFECT PROFILE OF
ANTI-TNF THERAPY?
JC Packham 1 , PT Dawes 1 , AB Hassell 1 , DL Mattey 1 .
1
Rheumatology, Staffordshire Rheumatology Centre, Stoke on Trent, Staffordshire, United Kingdom
46 USE OF PARENTERAL METHOTREXATE SIGNIFICANTLY REDUCES THE NEED FOR BIOLOGICAL
THERAPY
A Bharadwaj, S Agarwal, N Jeganathan, M Batley, A Hammond.
1
Rheumatology, Maidstone Hospital, Maidstone, Kent, United Kingdom
47 SCREENING FOR TB PRIOR TO ANTI-TNF THERAPY; IMPLEMENTATION OF THE BTS GUIDELINES IS
COST EFFECTIVE
J Pringle, A Stirling, MM Gordon, D Porter.
1
Department of Rheumatology, Gartnavel General Hospital, Glasgow, United Kingdom
48 ABATACEPT PROVIDED CLINICALLY MEANINGFUL IMPROVEMENTS IN MULTIPLE ASPECTS OF
HEALTH RELATED QUALITY OF LIFE (HRQoL) AND PHYSICAL FUNCTION THROUGH 2 YEARS OF
TREATMENT IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS (RA): RESULTS FROM THE AIM
AND ATTAIN TRIALS
P Emery 1 , T Li 2 , J Teng 2 , M Schiff 3 , M Luggen 4 .
1
Department of Rheumatology, University of Leeds, Leeds, United Kingdom; 2 Bristol Myers Squibb, Princeton, NJ,
United States; 3 Denver Arthritis Clinic, Denver, CO, United States; 4 Division of Immunology, University of Cincinnati
Medical Center, Cincinnati, OH, United States
49 ABATACEPT (Aba) PROVIDES LONG-TERM EFFICACY AND SIGNIFICANT SUSTAINED BENEFITS IN
CLINICAL AND PATIENT (Pt)-REPORTED OUTCOMES (PROs) THROUGH 2 YRS IN RHEUMATOID
ARTHRITIS (RA) PTS WITH AN INADEQUATE RESPONSE TO METHOTREXATE (MTX): THE
LONG-TERM EXTENSION (LTE) OF THE AIM BA IN INADEQUATE RESPONDERS TO MTX) TRIAL
P Emery 1 , A Russell 2 , JC Becker 3 , R Aranda 3 , T Li 4 , J Teng 5 , N Schmidely 6 , M LeBars 6 , LW Moreland 7 ,
Westhovens 8 , JM Kremer 9 .
1
Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom; 2 University of Alberta
Hospital, Edmonton, AB, Canada; 3 Global Clinical Research, Immunology, Bristol-Myers Squibb, Princeton, NJ,
United States; 4 Outcomes Research, Bristol-Myers Squibb, Princeton, NJ, United States; 5 Global Biometric
Sciences, Bristol-Myers Squibb, Princeton, NJ, United States; 6 Bristol-Myers Squibb, Ruiel-Malmaison, France;
7
University of Alabama, Birmingham, AL, United States; 8 Department of Rheumatology, UZ KU Leuven, Leuven,
Belgium; 9 Albany Medical College, The Center for Rheumatology, New York, NY, United States
50 LIPID-LOWERING WITH EITHER SIMVASTATIN OR EZETIMIBE ALTERS IMMUNOLOGICAL FUNCTION
IN PATIENTS WITH RHEUMATOID ARTHRITIS
SP Fairchild 1 , M Schenk 1 , C Bryson 1 , KM Maki-Petaja 2 , A Furlong 1 , OA Rosenwasser 1 , IB Wilkinson 2 , FC Hall 1 .
1
University of Cambridge Department of Clinical Medicine, Addenbrooke’s Hospital, Cambridge, Cambs, United
Kingdom; 2 Clinical Pharmacology Unit, University of Cambridge, Cambridge, United Kingdom
48

51 AN INTEGRATED SAFETY ANALYSIS OF ABATACEPT IN THE TREATMENT OF RHEUMATOID
ARTHRITIS ACROSS PATIENT TYPES AND BACKGROUND THERAPIES
B Combe 1 , SD Steinfeld 2 , JC Becker 3 , R Aranda 3 , T McCann 4 , ME Weinblatt 5 , LW Moreland 6 .
1
Immuno-Rhumatologie, Hopital Lapeyronie, Montpellier, France; 2 Department of Rheumatology, Erasme
University Hospital, Brussels, Belgium; 3 Global Clinical Research, Bristol-Myers Squibb, Princeton, NJ, United
States; 4 Global Biometric Sciences, Bristol-Myers Squibb, Princeton, NJ, United States; 5 Division of
Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Boston, MA, United States;
6
Division of Clinical Immunology and Rheumatology, The University of Alabama School of Medicine,
Birmingham, AL, United States
52 WHY DO SOME RHEUMATOLOGY PATIENTS CHOOSE NOT TO TAKE METHOTREXATE?
EJ Mulvey.
1
Rheumatology Department, Countess of Chester Hospital NHS Foundation Trust, Chester, Cheshire,
United Kingdom
53 ABATACEPT (ABA) PROVIDES SUSTAINED CLINICAL BENEFIT THROUGH 3 YEARS IN RHEUMA-
TOID ARTHRITIS (RA) PATIENTS (Pts) WITH INADEQUATE RESPONSES TO METHOTREXATE (MTX)
T Hammond 1 , P Emery 2 , R Aranda 3 , JC Becker 3 , Y Zhou 4 , M Dougados 5 , R Westhovens 6 .
1
Rheumatology Department, Maidstone Hospital, Kent, United Kingdom; 2 Academic Unit of Musculoskeletal
Disease, University of Leeds, Leeds, United Kingdom; 3 Global Clinical Research, Immunology, Bristol-Myers
Squibb, Princeton, NJ, United Kingdom; 4 Global Biometric Sciences, Bristol-Myers Squibb, Princeton, NJ,
United States; 5 Department of Rheumatology B, Hopital Cochin, Rene Descartes University, Paris, France;
6
Department of Rheumatology, UZ KU Leuven, Leuven, Belgium
54 MALIGNANCIES IN THE RHEUMATOID ARTHRITIS (RA) ABATACEPT (Aba) CLINICAL
DEVELOPMENT PROGRAM: AN UPDATED EPIDEMIOLOGICAL ASSESSMENT
TA Simon 1 , AL Smitten 2 , A Covucci 3 , J Franklin 4 , J Askling 5 , D Lacaille 6 , F Wolfe 7 , S Suissa 8 , M Hochberg 9 .
1
Global Epidemiology, Bristol-Myers Squibb, Hopewell, NJ, United States; 2 Duke University School of Medicine,
Durham, NC, United States; 3 Global Biostatistics, Bristol-Myers Squibb, Hopewell, NJ, United States; 4 ARC
Epidemiology Unit, University of Manchester, Manchester, United Kingdom; 5 Karolinska University Hospital
Solna, Stockholm, Sweden; 6 Arthritis Research Centre of Canada, University of British Columbia, Vancouver,
Canada; 7 National Data Bank for Rheumatic Diseases, Arthritis Research Foundation and University of Kansas,
Wichita, KS, United States; 8 McGill Pharmacoepidemiology Research Unit, Royal Victoria Hospital, Quebec,
Canada; 9 Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine,
Baltimore, MD, United States
55 BRONCHOSPASM ASSOCIATED WITH ANTI-TNF TREATMENT
SG Dubey 1 , N Kerrigan 1 , K Mills 1 , DGI Scott 1 .
1
Dept of Rheumatology, Norfolk and Norwich University Hospital, Colney Lane, Norfolk, United Kingdom
56 AN OBSERVATION OF A COMBINED RHEUMATOLOGY/ORTHOPAEDIC FOOT CLINIC TO DETERMINE
OUTCOME FROM THE CLINIC AND SURGICAL RESULTS
GH George.
1
Department of Rheumatology, Medway Maritime Hospital, Gillingham, Kent, United Kingdom
RHEUMATOID ARTHRITIS - AETIOPATHOGENESIS
57 CALCITONIN GENE-RELATED PEPTIDE CAUSES ENDOTHELIAL CELL PROLIFERATION IN VIVO
PI Mapp, MJ Turley, DF McWilliams, DA Walsh.
1
Academic Rheumatology, University of Nottingham, City Hospital, Nottingham, United Kingdom
49

58 AN IN VIVO CASCADE FOR BIOPHARMACEUTICALS IN DRUG DEVELOPMENT
E Rendall, A Midha, S Nicol, A Osborne, S Cruwys.
1
Discovery BioScience, AstraZeneca R&D Charnwood, Loughborough, Leicestershire, United Kingdom
59 INVESTIGATION OF THE ROLE OF P38 MAPK ALPHA AND DELTA ISOFORMS IN NON-RESPONSE TO
TNF BLOCKADE IN THE SYNOVIUM OF RHEUMATOID ARTHRITIS PATIENTS
LR Coulthard 1 , LD Church 1 , RJ Mathews 1 , S Churchman 1 , L Dickie 1 , M Buch 1 , R Reece 1 , A English 1 , AW Morgan 1 ,
S Gay 2 , P Emery 1 , MF McDermott 1 .
1
Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom; 2 Department of
Rheumatology, University Hospital, Zurich, Switzerland
60 TCRz dim LYMPHOCYTES DEFINE CIRCULATING EFFECTOR CELLS THAT MIGRATE TO INFLAMED
TISSUE
CL Gorman 1 , Z Zhang 1 , AC Vermi 1 , C Monaco 1 , T Vyse 2 , AP Cope.
1
Kennedy Institute of Rheumatology, Imperial College London, London, United Kingdom; 2 Department of
Rheumatology, Faculty of Medicine, Imperial College London, London, United Kingdom
61 AUTOREACTIVE SUPPRESSIVE CD8+ T CELL CLONES FROM PERIPHERAL BLOOD OF THE PATIENTS
WITH RHEUMATOID ARTHRITIS
HJ Baek 1 , LB Jarvis 2 , JSH Gaston 2 .
1
Department of Internal Medicine, Gachon University of Medicine and Science Gil Medical Center, Incheon,
Republic of Korea; 2 Department of Medicine, University of Cambridge, Cambridge, United Kingdom
62 THE REGULATION OF IL-7 PRODUCTION IN SYNOVIAL STROMAL CELLS IN RA IS DIFFERENT FROM
HEALTH
S Field 1 , E Jones 1 , A English 1 , R Reece 1 , P Emery 1 , F Ponchel 1 .
1
Leeds Institute of Molecular Medicine, Section Rheumatology, Leeds University, Leeds, United Kingdom
63 CIRCULATING LEVELS OF IL-7 IN RA
S Churchman 1 , S Field 1 , C Burgoyne 1 , A Brown 1 , N ElSayed 1 , P Emery 1 , F Ponchel 1 .
1
Leeds Institute of Molecular Medicine, Section Rheumatology, Leeds University, Leeds, United Kingdom
64 INTERFERON GAMMA DECREASES INTERLEUKIN 1β MEDIATED CARTILAGE LOSS IN RHEUMATOID
ARTHRITIS
CE Page 1 , S Smale 1 , SN Lauder 2 , SM Carty 2 , AS Williams 2 .
1
Rheumatology Department, University Hospital of Wales, Cardiff, United Kingdom; 2 Rheumatology Research
Laboratory, Cardiff University, Cardiff, United Kingdom
GENETICS
65 SNPS IN THE FOXP3 GENE REGION SHOW NO ASSOCIATION WITH JUVENILE IDIOPATHIC ARTHRI-
TIS (JIA) IN A UK CAUCASIAN POPULATION
TC Eastell 1 , A Hinks 1 , BSPAR Study Group, W Thomson 1 .
1
arc Epidemiology Unit, The University of Manchester, Manchester, United Kingdom
50

66 DO NON-INHERITED MATERNAL ANTIGENS INFLUENCE PREDISPOSITION TO RHEUMATOID
ARTHRITIS?
C Deighton 1 , J Worthington 2 , W Zhang 3 , M Doherty 3 , RF Lum 4 , LA Criswell 4 .
1
Department of Rheumatology, Derbyshire Royal Infirmary, Derby, United Kingdom; 2 ARC Epidemiology Research
Unit, University of Manchester, Manchester, United Kingdom; 3 Department of Academic Rheumatology,
Nottingham City Hospital, Nottingham, United Kingdom; 4 Rosalind Russell Medical Research Center for
Arthritis, University of California, San Francisco, CA, United States
67 PTPN22 HAPLOTYPE ANALYSIS IN UK RA AND JIA CASES AND CONTROLS
A Hinks 1 , A Barton 1 , S Eyre 1 , W Thomson 1 , J Worthington 1 .
1
ARC Epidemiology Unit, University of Manchester, Manchester, United Kingdom
68 THE SEARCH FOR SUSCEPTIBILITY VARIANTS FOR RHEUMATOID ARTHRITIS WITHIN THE PADI
REGION IN A CAUCASIAN POPULATION
HM Naseem 1 , J Worthington 1 , AC Barton 1 .
1
ARC Epidemiology Unit, University of Manchester, Manchester, Greater Manchester, United Kingdom
69 A WHOLE GENOME BY ASSOCIATION OF CHRONIC INFLAMMATORY ARTHRITIS
S John 1 , A Hinks 1 , N Shephard 1 , E Wang 2 , M Cargill 2 , Y Turpaz 2 , A Barton 1 , S Eyre 1 , J Bowes 1 , W Thomson 1 ,
G Kennedy 2 , J Worthington 1 .
1
ARC Epidemiology Unit, University of Manchester, Manchester, United Kingdom; 2 Affymetrix, Affymetrix Inc,
Santa Clara, United States
70 THE RELATIONSHIP OF INFLAMMATORY AND GENETIC FACTORS WITH FIBRINOLYSIS IN
RHEUMATOID ARTHRITIS
KMJ Douglas 1 , V Panoulas 1 , J Smith 2 , M Labib 2 , P Nightingale 3 , GJ Treharne 1 , GD Kitas 1 .
1
Department of Rheumatology, Dudley Group of Hospitals, Dudley, West Midlands, United Kingdom;
2
Department of Biochemistry, Dudley Group of Hospitals, Dudley, West Midlands, United Kingdom;
3
Department of Medical Statistics, University of Birmingham, Birmingham, West Midlands, United Kingdom
71 THE FREQUENCY OF THE SHARED EPITOPE IN RHEUMATOID ARTHRITIS IN DIFFERENT ETHNIC
POPULATIONS
CE Neville 1 , D Smillie 2 , W Hassan 3 .
1
Rheumatology, Stoke Mandeville Hospital, Aylesbury, Buckinghamshire, United Kingdom; 2 National Blood
Centre, Sheffield, United Kingdom; 3 Rheumatology, University Hospitals of Leicester, Leicester, United Kingdom
72 DOES SHARED EPITOPE STATUS INFLUENCE RESPONSE TO METHOTREXATE?
SL Hider 1 , W Thomson 1 , D Bunn 2 , M Lunt 1 , DP Symmons 1 .
1
arc Epidemiology Unit, University of Manchester, Manchester, United Kingdom; 2 Norfolk Arthritis Register,
Norfolk and Norwich University Hospital, Norwich, United Kingdom
73 ARE THERE ETHNIC DIFFERENCES IN METHOTREXATE TOXICITY?
SJ Levy, PDW Kiely.
1
Rheumatology, St Georges Healthcare NHS Trust, London, United Kingdom
74 A NOVEL SPLICE MUTATION IN TNFRSF1A IN A 16 YEAR OLD MALE AND HIS MOTHER, BOTH OF
WHOM HAVE TNF-RECEPTOR ASSOCIATED PERIODIC SYNDROME (TRAPS)
SM Churchman 1 , LD Church 1 , B Hayward 1 , S Savic 2 , HC Gooi 2 , P Emery 1 , MF McDermott 1 .
1
Leeds Institute of Molecular Medicine, University of Leeds, Leeds, West Yorkshire, United Kingdom;
2
Immunology, St. James University Hospital, Leeds, West Yorkshire, United Kingdom
51

75 RADIOLOGICAL DAMAGE IN RHEUMATOID ARTHRITIS IS ASSOCIATED WITH IL-6 AND IL-10
GENOTYPES INDEPENDENT OF AUTOANTIBODY PRODUCTION
I Marinou 1 , J Healy 1 , D Mewar 1 , DJ Moore 1 , MC Dickson 2 , MH Binks 2 , DS Montgomery 2 , K Walters 1 , AG Wilson 1 .
1
Section of Musculoskeletal Sciences, School of Medicine & Biomedical Sciences, The University of Sheffield,
Sheffield, United Kingdom; 2 GlaxoSmithKline R&D, Stevenage, United Kingdom
SPONDYLOARTHROPATHIES (INCLUDING PSORIATIC ARTHRITIS)
76 META-ANALYSIS OF THE EFFICACY AND SAFETY OF TNF-α INHIBITORS IN THE MANAGEMENT OF
PSORIATIC ARTHRITIS
AA Saad 1 , DM Ashcroft 1 , DPM Symmons 2 , PR Noyce 1 .
1
Drug Usage and Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, The University of
Manchester, Manchester, England, United Kingdom; 2 Arthritis Research Campaign Epidemiology Unit, The
University of Manchester, Manchester, England, United Kingdom
77 DIFFERENCES IN SPONDYLOARTHRITIS PROFILE BETWEEN CAUCASIAN AND SOUTH EAST ASIAN
PATIENTS SEEN IN NORTH EAST LONDON
E Roussou, K Malik, A Koukkoulli, N Sheli, A Sagovits.
1
Rheumatology and Rehabilitation King George Hospital, Barking Havering and Redbridge Trust, Ilford, Essex,
United Kingdom
78 THE CHARACTERISATION OF MUSCULOSKELETAL MANIFESTATIONS OF UNTREATED COELIAC
DISEASE (CD)
GPR Clunie 1 , B Kok 2 , JC Wyke 3 .
1
Department of Rheumatology, The Ipswich Hospital NHS Trust, Ipswich, Suffolk, United Kingdom; 2 Nutrition and
Dietetics Service, The Ipswich Hospital NHS Trust, Ipswich, Suffolk, United Kingdom; 3 Department of Medicine,
The Ipswich Hospital NHS Trust, Ipswich, Suffolk, United Kingdom
79 TO ASSESS THE IMPACT OF INTENSIVE PHYSIOTHERAPY DURING A FLARE OF ANKYLOSING
SPONDYLITIS
A Madan 1 , SJ Inman 2 , J Martindale 2 , D Grennan 1 , EG Chelliah 1 .
1
Rheumatology, Wrightington Hospital, Wrightington, Lancashire, United Kingdom; 2 Physiotherapy, Wrightington
Hospital, Wrightington, Lancashire, United Kingdom
80 TREATMENT OF ANKYLOSING SPONDYLITIS WITH ANTI-TNF THERAPY – ‘REAL-LIFE’ EXPERIENCE
L Flemming 1 , RN Jois 1 , M Somerville 1 , J Leeder 1 , K Gaffney 1 .
1
Rheumatology, Norfolk and Norwich University Hospital, Norwich, Norfolk, United Kingdom
81 DIAGNOSTIC RELIABILITY OF LOW-FIELD MAGNETIC RESONANCE IMAGING (MRI) FOR THE STUDY
OF NAIL AND DISTAL INTERPHALANGEAL (DIP) JOINT IN PSORIATIC ARTHRITIS (PsA)
R Scarpa 1 , E Soscia 2 , R Peluso 1 , M Atteno 1 , C Sirignano 2 , L Costa 1 , MND Di Minno 1 , S Iervolino 1 , MA Cimmino 3 ,
U Balestrieri 1 , L Satragno 4 , M Salvatore 2 .
1
Dpt of Clinical and Experimental Medicine, Rheumatology Research Unit, University Federico II, Naples, Italy, Italy;
2
National Council of Research, Radiology Unit - Biostructures and Bioimaging Institute, University Federico II,
Naples, Italy, Italy; 3 Dpt of Internal Medicine, Rheumatology Unit, University of Genoa, Genoa, Italy, Italy;
4
ESAOTE Group Italy, ESAOTE, Genoa, Italy, Italy
52

82 LACK OF TREATMENT EXPECTATIONS BY SPONDYLOARTHROPATHY PATIENTS (SpA), IN AN
AMBULATORY CARE SETTING, IS ASSOCIATED WITH WORSE CLINICAL OUTCOMES; THE EXPECT
STUDY
MA Stone 1,2 , R Sengupta 2 , A Papachristos 1 , J Rothman 1 , A Boonen 3 .
1
Department of Rheumatology, University of Toronto, Toronto, Canada; 2 Department of Rheumatology, Royal
National Hospital for Rheumatic Diseases, Bath, Avon, United Kingdom; 3 Department of Internal Medicine,
Division of Rheumatology and Caphri Research Institute, Maastricht, Netherlands
83 CARDIOMYOPATHY IN A PATIENT RECIEVING ANTI TNF THERAPY
A Moorthy 1 , S Moore 2 , A Clarke 2 , W Hassan 2 .
1
Rheumatology, Northampton General Hospital, Northampton, Northamptonshire, United Kingdom;
2
Rheumatology, University Hospitals of Leicester NHS Trust, Leicester, Leicestershire, United Kingdom
84 THE FIRST DESCRIPTION OF A PATIENT WITH ANKYLOSING SPONDYLITIS (AS) POSITIVE FOR
THE AS-NOT ASSOCIATED ALLELE B*2709, BUT ALSO FOR TWO ALLELES ASSOCIATED WITH THE
DISEASE
A Cauli 1 , A Vacca 1 , A Mameli 1 , MT Fiorillo 2 , G Passiu 1 , R Sorrentino 2 , A Mathieu 1 .
1
Rheumatology, University of Cagliari, Cagliari, Italy; 2 Cell Biology and Development, University “La Sapienza”,
Rome, Italy
85 INVESTIGATION OF ASSOCIATION OF THE DLG5 GENE WITH PSORIATIC ARTHRITIS
PY Ho, IN Bruce, J Worthington, A Barton.
1
arc-EU, The University of Manchester, Manchester, United Kingdom
86 ADALIMUMAB IS EFFECTIVE IN PATIENTS WITH PRERADIOGRAPHIC AXIAL
SPONDYLOARTHRITIS: RESULTS OF A 12-WEEK, RANDOMIZED CONTROLLED TRIAL
H Haibel 1 , M Rudwaleit 1 , F Heldmann 2 , J Listing 3 , R Wong 4 , H Kupper 5 , J Braun 6 , J Sieper 1 .
1
Charité Universitätsmedizin Berlin, Berlin, Germany; 2 St. Josefs-Krankenhaus, Herne, Germany; 3 German
Rheumatism Research Center, Berlin, Germany; 4 Abbott, Parsippany, NJ, United States;
5
Abbott GmbH & Co KG, Ludwigshafen, Germany; 6 Ruhr University Bochum, Bochum, Germany
87 TREATMENT WITH ADALIMUMAB (HUMIRA®) IS SAFE AND EFFECTIVE IN PSORIATIC
ARTHRITIS (PsA) PATIENTS IN REAL-LIFE CLINICAL PRACTICE: PRELIMINARY RESULTS OF
THE STEREO TRIAL
F van den Bosch 1 , NJ McHugh 2 , R Reece 3 , R Cooper 4 , B Manger 5 , P Goupille 6 , O FitzGerald 7 , M Kron 8 , M Frank 8 ,
H Kupper 8 , E Roedevand 9 , P Holck 10 , R Van Vollenhoven 11 , M Leirisalo-Repo 12 .
1
University Hospital, Gent, Belgium; 2 Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom;
3
Huddersfield Royal Infirmary, Huddersfield, United Kingdom; 4 Hope Hospital, Salford, United Kingdom;
5
Universität Erlangen-Nürnberg, Erlangen, Germany; 6 Hôpital Trousseau, CHU Tours, France; 7 St. Vincent’s
University Hospital, Dublin, Ireland; 8 Abbott GmbH & Co KG, Ludwigshafen, Germany; 9 St. Olavs Hospital,
Trondheim, Norway; 10 Silkeborg Centralsygehus, Silkeborg, Denmark; 11 Karolinska University Hospital,
Stockholm, Sweden; 12 University Hospital, Helsinki, Finland
88 A SYSTEMATIC REVIEW AND METAANALYSIS OF SLOW ACTING ANTI-RHEUMATIC DRUGS AND
TUMOUR NECROSIS FACTOR ANTAGONISTS FOR TREATMENT OF PSORIATIC ARTHRITIS
V Ravindran 1 , DL Scott 1 , EH Choy 1 .
1
Sir Alfred Baring Clinical Trials Unit, Academic Department of Rheumatology, King’s College London, London,
United Kingdom
53

89 PERCEPTIONS AMONGST GENERAL PRACTITIONERS REGARDING INFLAMMATORY BACK PAIN AND
ANKYLOSING SPONDYLITIS
RN Jois 1 , AJ MacGregor 1 , K Gaffney 1 .
1
Rheumatology, Norfolk and Norwich University Hospital, Norwich, Norfolk, United Kingdom
90 THE GLASGOW MRI SACROILIITIS SCORE (GMSS) – THE APPLICATION OF A NEW MRI SCORING
SYSTEM TO A COHORT OF ANKYLOSING SPONDYLITIS PATIENTS
MG Sambrook 1 , K Ong 1 , C Noble 2 , L Mackenzie 3 , D Kane 4 , RD Sturrock 3 .
1
Department of Radiology, Glasgow Royal Infirmary, Glasgow, United Kingdom; 2 Department of Physiotherapy,
Glasgow Royal Infirmary, Glasgow, United Kingdom; 3 Centre for Rheumatic Diseases, Glasgow Royal Infirmary,
Glasgow, United Kingdom; 4 Medicine, St James Hospital, Dublin, Ireland
91 EXERCISE IN ANKYLOSING SPONDYLITIS – THE PATIENT PERSPECTIVE
SB Porter 1 , J Smith 2 , L Goodacre 1 , J Goodacre 1 .
1
Lanashire School of Health and Postgraduate Medicine, University of Central Lancashire, Preston, Lancashire,
United Kingdom; 2 Department of Psychology, University of Central Lancashire, Preston, Lancashire, United
Kingdom
92 NON-RESPONSE TO BIOLOGIC DRUGS IN PSORIATIC ARTHRITIS – “SWITCHING” SHOULD ALWAYS
BE CONSIDERED
LC Coates 1 , H Marzo-Ortega 1 , DJ Bryer 1 , A Bennett 1 , AD Fraser 1 , P Emery 1 .
1
Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, West Yorkshire, United Kingdom
93 ARE HIGHLY SENSITIVE CRP AND SERUM AMYLOID A BETTER MARKERS OF DISEASE ACTIVITY IN
PATIENTS WITH ANKYLOSING SPONDYLITIS?
N Sathi, RK Mallya, JK Dawson, A Griffiths, R Wiswell, J Novak, K Eccleston, T Connolly.
1
Rheumatology, Countess of Chester Hospital, Chester, Cheshire, United Kingdom; 2 Rheumatology, Halton General
Hospital, Runcorn, Cheshire, United Kingdom; 3 Rheumatology, St. Helens and Knowsley NHS Trust, St. Helens,
Merseyside, United Kingdom
94 GENETIC SUSCEPTIBILITY FOR PSORIATIC ARTHRITIS – INVESTIGATION OF GENES NAT9, SCL9A3R1
AND RAPTOR ON CHROMOSOME 17q25
CE Filer 1 , A Barton 1 , IN Bruce 1 , J Worthington 1 , P Ho 1 .
1
arc-Epidemiology Unit, The University of Manchester, Manchester, United Kingdom
95 STUDY OF WORK STATUS AMONGST PEOPLE WITH ANKYLOSING SPONDYLITIS RECEIVING
BIOLOGICAL THERAPIES
AC Keat 1 , K Gaffney 2 , AK Gilbert 1 , C Harris 1 , J Leeder 2 .
1
Arthritis Centre, Northwick Park Hospital, Harrow, Middlesex, United Kingdom; 2 Rheumatology Department,
Norfolk and Norwich University Hospital, Norwich, Norfolk, United Kingdom
96 DISCRIMINATING BETWEEN REGULATORY AND NON-REGULATORY CD4+ T CELLS
RC Duggleby 1 , JSH Gaston 1 .
1
Medicine, University of Cambridge, Cambridge, United Kingdom
97 ANKYLOSING SPONDYLITIS MIMICS: TWO CASES OF OSTEITIS CONDENSANS ILII
D Singh 1 , T Sikdar 2 , S Dahiya 3 .
1
Department of Medicine, Princess Alexandra Hospital, Harlow, Essex, United Kingdom; 2 Department of Radiology,
Princess Alexandra Hospital, Harlow, Essex, United Kingdom; 3 Department of Rheumatology, Princess Alexandra
Hospital, Harlow, Essex, United Kingdom
54

98 DOES MAGNETIC RESONANCE IMAGING OF THE SACRO-ILIAC JOINTS OF PATIENTS WITH
SUSPECTED INFLAMMATORY LOW BACK PAIN INFLUENCE RHEUMATOLOGISTS’ SUBSEQUENT
DIAGNOSIS AND TREATMENT?
C Crabtree 1 , G Price 2 , K Walker-Bone 3 .
1
Rheumatology, Brighton and Sussex University Hospitals NHS Trust, Brighton, East Sussex, United Kingdom;
2
Radiology, Brighton and Sussex University Hospitals NHS Trust, Brighton, East Sussex, United Kingdom;
3
Rheumatology, Brighton & Sussex Medical School, Brighton, East Sussex, United Kingdom
99 AN ANALYSIS OF FAMILY HISTORY IN A COHORT OF SUBJECTS WITH PSORIATIC ARTHRITIS
LE Coates 1 , NJ McHugh 1 , CR Carmichael 2 , N Waldron 1 , E Korendowych 1 .
1
Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; 2 Bath Institute for
Rheumatic Diseases, Bath, United Kingdom
100 NEW ONSET PSORIATIC ARTHRITIS ON WITHDRAWAL OF EFALIZUMAB
S Agarwal 1 , R Groves 2 , JN Barker 2 , B Kirkham 1 .
1
Department of Rheumatology, Guy’s and St. Thomas’ NHS Foundation Trust, London, United Kingdom;
2
St. John’s Institute of Dermatology, St. Thomas’ Hospital, London, United Kingdom
101 OUTCOME OF PATIENTS SEEN IN THE ANKYLOSING SPONDYLITIS SPECIALTY CLINIC OF
A DISTRICT GENERAL HOSPITAL
LJ Young, S Hicks.
1
Rheumatology, Royal Berkshire Hospital, Reading, Berkshire, United Kingdom
102 THE MCID FOR RESPONSE TO TNF BLOCKERS VARIES WIDELY DEPENDING ON THE METHOD
CHOSEN TO CALCULATE THE MCID
V Boyce 1 , D Beaton 2,3 , RA Govinda 3 , AM Maetzel 4 , RD Inman 3,4,5 , V Lapp 4,5,6 , MA Stone 1,2,3 .
1
Department of Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom;
2
School for Health, University of Bath, Bath, United Kingdom; 3 Mobility Program, St Michaels Hospital, Toronto,
Canada; 4 Toronto General Research Institute, Toronto, ON, Canada; 5 Department of Medicine, Toronto Western
Hospital, Toronto, ON, Canada; 6 Toronto Western Research Institute, Toronto, ON, Canada
103 PSORIATIC ARTHRITIS AND PSORIASIS: A QUALITATIVE STUDY EXPLORING QUALITY OF LIFE
ISSUES
CA Aitken 1 , M Anderson 2 , A Whyte 3 , T Adams 1 , H Poole 3 .
1
Faculty of Health and Applied Social Sciences, Liverpool John Moores University, Liverpool, Merseyside, United
Kingdom; 2 Academic Rheumatology, University Hospital Aintree, Liverpool, Merseyside, United Kingdom;
3
Faculty of Science, Liverpool John Moores University, Liverpool, Merseyside, United Kingdom
104 REGULATORY IL4+CD8+ T CELLS IN AS PATIENTS AND HEALTHY CONTROLS
LB Zhang 1 , LB Jarvis 1 , JS Gaston 1 .
1
Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom
105 ANTI-TNF THERAPY FOR PSORIATIC ARTHRITIS. CAN PATIENTS PERFORM THEIR OWN JOINT
COUNTS – A DGH EXPERIENCE
CE Page, C Campbell, RM Goodfellow, JC Martin, C Rhys-Dillon.
1
Rheumatology Department, Royal Glamorgan Hospital, Llantrisant, S. Wales, United Kingdom
106 SUSTAINED RESPONSE TO BIOLOGIC THERAPIES OVER TWO YEARS IN RESISTANT PSORIATIC
ARTHRITIS
LC Coates 1 , H Marzo-Ortega 1 , DJ Bryer 1 , LS Cawkwell 1 , DA Pickles 1 , AD Fraser 1 , P Emery 1 .
1
Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom
55

107 SUSTAINED RESPONSE TO LONG-TERM BIOLOGICS IN ANKYLOSING SPONDYLITIS: THE MAJORITY
OF PATIENTS CONTINUE ON THE SAME DRUG AFTER TWO YEARS
LC Coates 1 , H Marzo-Ortega 1 , DJ Bryer 1 , LS Cawkwell 1 , DA Pickles 1 , AD Fraser 1 , P Emery 1 .
1
Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom
108 NON RESPONSE AND SWITCHING IN ANKYLOSING SPONDYLITIS: A RARE OCCURRENCE
H Marzo-Ortega 1 , LC Coates 1 , DJ Bryer 1 , AN Bennett 1 , AD Fraser 1 , P Emery 1 .
1
Academic Department of Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom
109 IS THERE AN ASSOCIATION BETWEEN DISEASE ACTIVITY AND OSTEOPENIA/OSTEOPOROSIS IN A
COHORT OF PATIENTS WITH RIGOROUSLY DEFINED ANKYLOSING SPONDYLITIS?
LE Coates 1 , PA Lewis 2 , C Vasler 2 , MC Griffin 1 , DM Elvins 1 , AK Bhalla 1 , The BIAS Study Group.
1
Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; 2 Mathematical Sciences,
University of Bath, Bath, United Kingdom
110 AUDIT OF PHYSICAL THERAPY IN ANTI-TNF TREATED PTS WITH ANKYLOSING SPONDYLITIS
SG Dubey 1 , J Leeder 1 , JK Gaffney 1 .
1
Dept of Rheumatology, Norfolk and Norwich University Hospital, Colney Lane, Norwich, Norfolk, United Kingdom
111 THE PSORIASIS AREA SEVERITY INDEX (PASI) IN PSORIATIC ARTHRITIS
E Korendowych 1 , N Waldron 1 , CR Carmichael 2 , NJ McHugh 1 .
1
Royal National Hospital for Rheumatic Disease, Bath, Somerset, United Kingdom; 2 Bath Institute for Rheumatic
Diseases, Bath, Somerset, United Kingdom
112 PAMIDRONATE INFUSIONS FOR ANKYLOSING SPONDYLITIS GIVE SIGNIFICANT BENEFIT TO ONLY A
MINORITY OF PATIENTS
NJ Marshall 1,2 , A Pratt 1,2 , LJ Kay 1,2 .
1
Musculoskeletal Unit, Freeman Hospital, Newcastle upon Tyne, United Kingdom; 2 Musculoskeletal Research
Group, Newcastle University, Newcastle upon Tyne, United Kingdom
OSTEOARTHRITIS
113 SEVERE OSTEOARTHRITIS IS ASSOCIATED WITH SIMILAR FATIGUE AND GREATER PAIN SCORES
THAN RHEUMATOID ARTHRITIS, AT COMPARABLE LEVELS OF DISABILITY
S Stebbings 1 , J Highton 1 , D McNamara 1 .
1
Medicine, University of Otago School of Medicine, Dunedin, New Zealand
114 PERSONAL IMPACT OF DISABILITY IN OSTEOARTHRITIS: VALIDATION OF THE PI HAQ
A Tasker 1 , S Hewlett 2 , ID Learmonth 3 , V Wylde 3 .
1
Avon Orthopaedic Centre, Southmead Hospital, Bristol, United Kingdom; 2 Health and Social Care, University of
West of England, Bristol, United Kingdom; 3 Orthopaedic Surgery, University of Bristol, Bristol, United Kingdom
115 INTRAARTICULAR HIP BLOCK INJECTIONS: ARE THEY EFFECTIVE?
F Rahmeh, H Wells, SC Richards.
1
Rheumatology, Poole Hospital, Poole, United Kingdom
116 ROLE OF HYDROXYCHLOROQUINE IN MANAGEMENT OF OSTEOARTHRITIS
SK Sibtain 1 , S Kallankara 1 , TJ Gillott 1 , DW James 1 , TJ Tait 1 .
1
Department of Rheumatology, Diana Princess of Wales Hospital, Grimsby, United Kingdom
56

117 PATIENT PREFERENCE IS A STRONG PREDICTOR OF RESPONSE TO TREATMENT –
THE KIVIS STUDY
LM Thomas 1 , H Platten 2 , A Hassan 2 , KJ Jordan 3 , NK Arden 2 , I Reading 2 , JM Ledingham 4 .
1
Rheumatology Department, MDHU Portsmouth, Portsmouth, Hampshire, United Kingdom; 2 Rheumatology
Department, Southampton University Hospital Trusts, Southampton, Hampshire, United Kingdom;
3
Rheumatology Department, Brighton and Sussex University Trust, Brighton, Sussex, United Kingdom;
4
Rheumatology Department, Queen Alexandra Hospital, Portsmouth, Hampshire, United Kingdom
118 LUMIRACOXIB HAS A SIMILAR BLOOD PRESSURE PROFILE TO PLACEBO IN ARTHRITIS PATIENTS
A Whitehead 1 , M Simmonds 1 , B Mellein 2 , T Friede 2 , X Gitton 2 , P Sallstig 2 .
1
MPS Research Unit, University of Reading, Reading, United Kingdom; 2 Novartis Pharma AG, Basel, Switzerland
119 LUMIRACOXIB 100 MG OD IS AS EFFECTIVE AS CELECOXIB 200 MG OD IN THE LONG-TERM
MANAGEMENT OF OSTEOARTHRITIS PAIN
K Pavelka 1 , S Yu 2 , S Litschig 3 , R Rebuli 3 , A Weinzierl-Hinum 3 , R Alten 4 .
1
Institute of Rheumatology, Charles University, Prague, Czech Republic; 2 Novartis Pharmaceuticals Corporation,
East Hanover, NJ, United States; 3 Novartis Pharma AG, Basel, Switzerland; 4 Schlosspark-Klinik, Teaching
Hospital University of Medicine, Berlin, Germany
120 INCIDENCE RATES OF UPPER GASTROINTESTINAL ULCER COMPLICATIONS IN OSTEOARTHRITIS
PATIENTS OF LOW (

125 GOUT IN PALEOPATHOLOGY; THE ELUSIVE NATURE OF URATE
DR Swinson 1 , M Brickley 1 , J Snaith 3 , J Buckberry 2 .
1
Institute of Archaeology and Antiquity, Birmingham University, Birmingham, United Kingdom; 2 Dept of
Archaeological Sciences, Bradford University, Bradford, Yorkshire, United Kingdom; 3 School of Chemistry,
Birmingham University, Birmingham, United Kingdom
CASE REPORTS (I)
126 A CASE OF HCV INFECTION ASSOCIATED WITH CRYOGLOBULAEMIC VASCULITIS RESPONDED TO
CYCLOPHOSPHAMIDE, STEROIDS AND MYCOPHENOLATE MOFETIL BEFORE ANTI-VIRAL THERAPY
A Al-Ansari 1 , C White 2 , G Kallarackal 3 .
1
Rheumatology Department, Leicester Royal Infirmary, Leicester, United Kingdom; 2 Medical Department, Kettering
General Hospital, Kettering, Northants, United Kingdom; 3 Rheumatology Department, Kettering General Hospital,
Kettering, Northants, United Kingdom
127 HEPATITIS E IN A PATIENT TREATED WITH METHOTREXATE FOR PSORIATIC ARTHRITIS
L Das 1 , SM Jones 2 , AJ Godkin 2 .
1
Rheumatology, Essex Rivers NHS Trust, Colchester, Essex, United Kingdom; 2 Rheumatology, Cardiff and Vale NHS
Trust, Cardiff, South Glamorgan, United Kingdom; 3 Gastroenterology, Cardiff and Vale NHS Trust, Cardiff, South
Glamorgan, United Kingdom
128 METHOTREXATE PNEUMONITIS PRECIPITATED BY SWITCHING FROM ORAL TO PARENTERAL
ADMINISTRATION
CA Kelly, H Aspey, A Todd, V Saravanan, M Rynne.
1
Rheumatology and General Medicine, Queen Elizabeth Hospital, Gateshead, Tyne and Wear, United Kingdom
129 SIGNIFICANT NEUTROPAENIAS ON ETANERCEPT
C Vandevelde 1 , K Gadsby 1 , C Deighton 1 .
1
Department of Rheumatology, Derbyshire Royal Infirmary, Derby, Derbyshire, United Kingdom
130 ADALIMUMAB INDUCED INTERSTITIAL PNEUMONITIS
BG Chikura 1 , S Ismaeel 1 , AR Clewes 1 , VE Abernerthy 1 , JK Dawson 1 .
1
Rheumatology, St Helens Hospital, St Helens, Mersyside, United Kingdom
131 COCAINE INDUCED MIDLINE DESTRUCTIVE LESIONS
SM Rachapalli, PDW Kiely.
1
Rheumatology, St George’s Healthcare NHS Trust, London, United Kingdom
132 PRIMARY CARDIAC LYMPHOMA: REPORT OF A RARE TUMOUR IN A HIV-NEGATIVE PATIENT WITH
PRIMARY SJOGREN’S SYNDROME
JKC Yoong 1 , R Ramason 2 .
1
Rheumatology & Immunology, Singapore General Hospital, Singapore; 2 Medicine, Tan Tock Seng Hospital,
Singapore
133 HEPATOTOXICITY WITH SULFASALAZINE: DATA FROM A LOCAL SURVEILLANCE SYSTEM OF
SERIOUS ADVERSE EVENTS IN PATIENTS WITH INFLAMMATORY ARTHRITIS
P Jobanputra, R Amaresena, F Maggs, E Rankin, S Bowman, R Jubb, D Homer.
1
Department of Rheumatology, Selly Oak Hospital, UHB NHS Foundation Trust, Birmingham, West Midlands,
United Kingdom
58

134 SUCCESSFUL TREATMENT OF MYOCARDITIS IN ADULT-ONSET STILL’S DISEASE WITH
INTRAVENOUS IMMUNOGLOBULIN AND MAINTENANCE OF REMISSION WITH ETANERCEPT
A Kuek 1 , A Weerakoon 2 , K Ahmed 2 , AJK Ostor 1 .
1
Department of Rheumatology, Addenbrookes Hospital, Cambridge, Cambridgeshire, United Kingdom;
2
Department of Rheumatology, Princess Alexandra Hospital, Harlow, Essex, United Kingdom
135 REFRACTORY TAKAYASU’S ARTERITIS TREATED SUCCESSFULLY WITH ETANERCEPT IN A
PATIENT WITH ANKYLOSING SPONDYLITIS
A Abhishek 1 , P Courtney 1 .
1
Department of Rheumatology, City Hospital Nottingham, Nottingham, United Kingdom
136 MYCOBACTERIUM HAEMOPHILUM SEPTIC ARTHRITIS OF PROSTHETIC ELBOW JOINT IN
RHEUMATOID ARTHRITIS
HR Chua 1 , A Chua 2 , A Lim 3 .
1
Medicine, National University Hospital, Singapore, Singapore, Singapore; 2 Medicine, National University
Hospital, Sinagpore, Singapore, Singapore; 3 Medicine, National University Hospital, Singapore, Singapore,
Singapore
137 AMLODIPINE INDUCED MYOPATHY
KK Putchakayala 1 , JE Brockbank 1 , WW Tun 1 , BM Daly 2 , S Nayak 3 .
1
Dept of Rheumatology, Royal Blackburn Hospital, Blackburn, Lancashire, United Kingdom; 2 Dept of
Dermatology, Royal Blackburn Hospital, Blackburn, Lancashire, United Kingdom; 3 Dept of Histopathology,
Royal Blackburn Hospital, Blackburn, Lancashire, United Kingdom
138 SCURVY – A VASCULITIS MIMIC
SG Dubey 1 , O Martin 1 , S Karthiga 1 , RA Watts 1 , GP Clunie 1 .
1
Dept of Rheumatology, Ipswich Hospital NHS Trust, Heath Lane, Ipswich, United Kingdom
139 A CASE OF RAPIDLY PROGRESSIVE SYSTEMIC SCLEROSIS (SSC) AS A PARANEOPLASTIC
SYNDROME
SC Earl 1 , RG Hull 2 , FC McCrae 2 , JM Ledingham 2 .
1
Rheumatology, North Hampshire Hospital, Basingstoke, Hampshire, United Kingdom; 2 Rheumatology, Queen
Alexandra Hospital, Portsmouth, Hampshire, United Kingdom
140 ISOLATED MYOSITIS OF INFRASPINATUS MUSCLE PRESENTING AS TREATMENT RESISTANT
ROTATOR CUFF LESION
A Weerakoon 1 , T Sikdar 2 , S Dahiya 1 , K Ahmed 1 .
1
Department of Rheumatology, Princess Alexandra Hospital, Harlow, Essex, United Kingdom; 2 Department of
Radiology, Princess Alexandra Hospital, Harlow, Essex, United Kingdom
141 TAKEN ABACK: A SUCCESSFULLY TREATED CASE OF SEVERE POLYARTICULAR SEPSIS WITH AN
UNUSUAL PRECIPITANT
TJ Commerford 1 , M Lloyd 2 , N Cumberland 3 , N Hughes 4 .
1
Medical SHO, Frimley Park Hospital, Frimley, Surrey, United Kingdom; 2 Rheumatology, Frimley Park Hospital,
Frimley, Surrey, United Kingdom; 3 Microbiology, Frimley Park Hospital, Frimley, Surrey, United Kingdom;
4
Radiology, Frimley Park Hospital, Frimley, Surrey, United Kingdom
142 TWO CASES OF SCLEROSING OSTEOMYELITIS – DIFFICULT TO DIAGNOSE, DIFFICULT TO TREAT
SE Medley, PI Pitt.
1
Department of Rheumatology, Princess Royal University Hospital, Farnborough, Kent, United Kingdom
59

143 A CASE OF PROCTITIS IN A PATIENT WITH RHEUMATOID ARTHRITIS DURING TREATMENT WITH
ETANERCEPT
JD Pauling 1 , MA Stone 1,2,3 .
1
Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; 2 Division of Medicine,
University of Toronto, Toronto, ON, Canada; 3 School for Health, University of Bath, Bath, Somerset, United
Kingdom
144 UNUSUAL ORGANISM CAUSING SEPTIC ARTHRITIS IN A PATIENT ON BIOLOGIC THERAPY
A Moorthy 1 , A Clarke 2 , A Kinder 2 .
1
Dept of Rheumatology, Northampton General Hospital, Northampton, United Kingdom; 2 Dept of Rheumatology,
University Hospitals of Leicester NHS Trust, Leicester, United Kingdom
145 FIBRODYSPLASIA OSSIFICANS PROGRESSIVA: LUMPS, BUMPS AND BIOLOGICS
I Atukorala 1 , BP Wordsworth 1 .
1
Department of Rheumatology, Nuffield Orthopaedic Centre, Headington, Oxford, United Kingdom
146 A MYCOBACTERIUM AVIUM INTRACELLULARE INFECTION AFTER TREATMENT WITH ADALIMUMAB
A Al-Ansari 1 , A Samanata 1 .
1
Rheumatology, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom; 2 Rheumatology, University
Hospitals of Leicester NHS Trust, Leicester, United Kingdom
147 SULPHASALAZINE INDUCED DRESS SYNDROME IN A PATIENT WITH INFLAMMATORY ARTHRITIS
EJ Coulson 1 , JD Hamilton 1 , B Thompson 1 , V Saravanan 1 , CA Kelly 1 .
1
Department of Rheumatology, Queen Elizabeth Hospital, Gateshead, United Kingdom
148 IS LEFLUNOMIDE TO BE BLAMED?
KT Yein 1 , D Rees 1 , R Williams 1 .
1
Rheumatology, The County Hospital, Hereford, Herefordshire, United Kingdom
149 DEVELOPMENT OF POLYMYOSITIS AFTER TAKING TADALAFIL, AN ORAL
PHOSPHODIESTERASE-5 INHIBITOR
B Thompson, A Pratt, B Griffiths.
1
Department of Rheumatology, Freeman Hospital, Newcastle-upon-Tyne, United Kingdom
150 PLASMA EXCHANGE AND RITUXIMAB FOR THE TREATMENT OF REFRACTORY
CRYOGLOBULINAEMIA
N Mo, N Amos, MH Pritchard, A Negi.
1
Rheumatology, University Hospital of Wales, Cardiff, South Glamorgan, United Kingdom
60

POSTER VIEWING 2 - THURSDAY
SJOGREN’S SYNDROME AND OTHER CONNECTIVE TISSUE DISORDERS
151 RESISTANT CASES OF PATIENTS WITH POLYMYALGIA RHEUMATICA
AM Salih.
1
Rheumatology, Warrington Hospital, Warrington, Cheshire, United Kingdom
152 PERIPHERAL SYNOVITIS IN POLYMYALGIA RHEUMATICA
AM Salih.
1
Rheumatology, Warrington Hospital, Warrington, Cheshire, United Kingdom
153 ENDOTHELIAL RESPONSES USING DIGITAL IONTOPHORESIS WITH LASER DOPPLER IMAGING IN
IDIOPATHIC INFLAMMATORY MYOPATHY
H Gunawardena 1,2 , ND Harris 2,3 , C Carmichael 2 , NJ McHugh 1,2 .
1
Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; 2 School for Health,
University of Bath, Bath, United Kingdom; 3 Clinical Measurements, Royal National Hospital for Rheumatic
Diseases, Bath, United Kingdom
154 SCREENING FOR ANTI-SYNTHETASE AUTOANTIBODIES IN PATIENTS WITH INTERSTITIAL
PNEUMONIA
H Gunawardena 1,2 , ZE Betteridge 2 , J North 2 , G Robinson 3 , NM Foley 4 , NJ McHugh 1,2 .
1
Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; 2 School for Health,
University of Bath, Bath, United Kingdom; 3 Radiology, Royal United Hospital, Bath, United Kingdom; 4 Respiratory
Medicine, Royal United Hospital, Bath, United Kingdom
155 CARDIO-RESPIRATORY INVOLVEMENT IN SJOGREN’S SYNDROME
EMA McCausland 1 , NW Liggett 1 , RP Convery 1 .
1
Department of Rheumatology, Craigavon Area Hospital, Craigavon, Northern Ireland, United Kingdom
156 HLA CLASS II AND SEROLOGICAL PROFILES OF UK CAUCASIAN PATIENTS WITH MYOSITIS
OVERLAPPING WITH CONNECTIVE TISSUE DISEASE
H Chinoy 1,2 , F Salway 2 , N Fertig 3 , CV Oddis 3 , WE Ollier 2 , RG Cooper 1 .
1
Rheumatic Diseases Centre, Hope Hospital, Salford, United Kingdom; 2 Centre for Integrated Genomic Research,
The University of Manchester, Manchester, United Kingdom; 3 Division of Rheumatology & Clinical Immunology,
University of Pittsburgh School of Medicine, Pittsburgh, PA, United States
SCLERODERMA AND RELATED DISORDERS
157 CONTRACTION OF FIBROBLAST COLLAGEN GELS BY SCLERODERMA EPIDERMIS
A Nuttall, X Shiwen, N Aden, C Denton, D Abraham, R Stratton.
1
Centre for Rheumatology, Royal Free Hospital and University College School of Medicine, London,
United Kingdom
158 CLINICAL BURDEN OF SEVERE DIGITAL VASCULOPATHY IN SYSTEMIC SCLEROSIS
SI Nihtyanova 1 , GM Brough 1 , CM Black 1 , CP Denton 1 .
1
Centre for Rheumatology, Royal Free Hospital, London, United Kingdom
61

159 EXPRESSION OF ADVANCED GLYCATION END PRODUCTS (AGE) AND THEIR RECEPTOR (RAGE) IN
SKIN FROM PATIENTS WITH SYSTEMIC SCLEROSIS
CA Davies 1 , M Jeziorska 1 , AJ Freemont 1 , AL Herrick 2 .
1
Division of Regenerative Medicine, University of Manchester, Manchester, United Kingdom; 2 Division of
Epidemiology and Health Sciences, University of Manchester, Manchester, United Kingdom
160 MYOSITIS IN PATIENTS WITH ANTI-PM-SCL IS ASSOCIATED WITH ANTIBODY LEVEL AND
RECOGNITION OF 80KD PROTEINS
SC Jamal 1 , JC Parker 1 , CC Bunn 1 .
1
Dept of Clinical Immunology, Royal Free Hospital, London, United Kingdom
161 MICROVASCULAR REGULATORY RESPONSES IN SYSTEMIC SCLEROSIS
H Gunawardena 1,2 , ND Harris 2,3 , C Carmichael 2 , NJ McHugh 1,2 .
1
Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; 2 School for Health,
University of Bath, Bath, United Kingdom; 3 Clinical Measurements, Royal National Hospital for Rheumatic
Diseases, Bath, United Kingdom
162 SEROLOGICAL SUBSETS AND SUBTYPES OF DIFFUSE PARENCHYMAL LUNG DISEASE IN
SCLERODERMA SPECTRUM DISORDERS AND IDIOPATHIC INFLAMMATORY MYOPATHY
H Gunawardena 1,2 , G Robinson 3 , ZE Betteridge 2 , C Carmichael 2 , J North 2 , NM Foley 4 , E Korendowych 1,2 ,
NJ McHugh 1,2 .
1
Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; 2 School for Health,
University of Bath, Bath, United Kingdom; 3 Radiology, Royal United Hospital, Bath, United Kingdom;
4
Respiratory Medicine, Royal United Hospital, Bath, United Kingdom
163 TOTAL PARENTERAL NUTRITION – A LIFE-SAVING TREATMENT FOR SYSTEMIC
SCLEROSIS-RELATED INTESTINAL FAILURE
M Brown 1 , A Teubner 2 , J Shaffer 2 , A Herrick 1 .
1
Rheumatic Diseases Centre, Hope Hospital, Salford, Greater Manchester, United Kingdom; 2 Intestinal Failure Unit,
Hope Hospital, Salford, Greater Manchester, United Kingdom
164 ASSESSMENT OF MICROCIRCULATORY CHANGES IN RESPONSE TO IV ILOPROST IN SYSTEMIC
SCLEROSIS
P Shah, TL Moore, A Herrick.
1
Rheumatic Diseases Centre, University of Manchester, Hope Hospital, Salford, Greater Manchester,
United Kingdom
165 A SEARCH FOR CONSENSUS IN THE ASSESSMENT OF DEPRESSION IN SYSTEMIC SCLEROSIS
PATIENTS
N Reay 1 .
1
Academic and Clinical Unit of Musculoskeletal Nursing, University of Leeds, Leeds, West Yorkshire,
United Kingdom
166 FOCAL ADHESION KINASE IS NECESSARY FOR PRO-FIBROTIC GENE EXPRESSION IN NORMAL AND
SCLERODERMA FIBROBLASTS
X Shiwen 1 , S Liu 2 , L Kennedy 2 , CM Black 1 , CP Denton 1 , A Least 2 , DJ Abraham 1 .
1
Centre for Rheumatology, Royal Free and University College Medical School, London, United Kingdom;
2
CIHR Group in Skeletal Development and Remodeling, Division of Oral Biology, Schulich School of Medicine
and Dentistry, University of Western Ontario, London, ON, Canada
62

167 CONSTITUTIVE ACTIVATION OF p42/44 MAP KINASE SIGNALLING IN MICE WITH
FIBROBLAST-SPECIFIC DELETION OF TβRII
K Khan 1 , P Leoni 1 , RK Hoyles 1 , X Shiwen 1 , DJ Abraham 1 , CP Denton 1 .
1
Centre for Rheumatology, Royal Free & University College Medical School, London, United Kingdom
SLE AND ANTIPHOSPHOLIPID SYNDROME
168 EFFECTS OF RITUXIMAB ON DISEASE ACTIVITY, PULMONARY FUNCTION AND HEALTH STATUS IN
SLE PATIENTS
JA Reynolds 1 , V Toescu 1,2 , CS Yee 1,2 , A Prabu 1,2 , D Situnayake 1 , C Gordon 1,2 .
1
Department of Rheumatology, City Hospital, Birmingham, West Midlands, United Kingdom; 2 Department of
Rheumatology, Division of Immunity and Infection, University of Birmingham, Birmingham, West Midlands,
United Kingdom
169 THE LIGHT CHAIN OF A HUMAN MONOCLONAL ANTIPHOSPHOLIPID ANTIBODY HAS A DRAMATIC
INFLUENCE ON ITS FUNCTIONAL PROPERTIES IN AN IN VIVO MOUSE MODEL
I Giles 1 , X Liu 2 , M Newton-West 3 , R Swerlick 3 , A Lambrianides 1 , P Chen 4 , D Latchman 1 , D Isenberg 1 , A Rahman 1 ,
S Pierangeli 2 .
1
Centre for Rheumatology Research/Division of Medicine _ Medical Molecular Biology Unit, University College
London, London, United Kingdom; 2 Division of Rheumatology/Department of Medicine, University of Texas
Medical Branch, Galveston, TX, United States; 3 Emory Skin Disease Research Centre, Emory University School
of Medicine, Atlanta, GA, United States; 4 Division of Rheumatology/Department of Medicine, University of
California at Los Angeles, Los Angeles, CA, United States
170 ASSOCIATION BETWEEN INFLAMMATORY MARKERS AND ENDOTHELIAL DYSFUNCTION IN
PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
SV Shevchuk 1 .
1
Rheumatology, Ukrainian State Scientific Research Institute of Invalid Rehabilitation, Vinnytsya, Ukraine
171 PURIFIED IgG FROM PATIENTS WITH DIFFERENT CLINICAL MANIFESTATIONS OF THE
ANTIPHOSPHOLIPID SYNDROME HAVE DIFFERENTIAL EFFECTS UPON THE NF-κB AND
p38MAPK SIGNALLING PATHWAYS IN MONOCYTES
A Lambrianides 1 , CJ Carroll 1 , C Pericleous 1 , W Heywood 1 , K Mills 1 , DS Latchman 1 , DA Isenberg 1 , SS Pierangeli 2 ,
PA Townsend 3 , A Rahman 1 , IP Giles 1 .
1
University College London, London, United Kingdom; 2 Division of Rheumatology/Department of Medicine,
University of Texas Medical Branch, Galveston, TX, United States; 3 Human Genetics Division, University of
Southampton, Southampton, United Kingdom
172 EXPLORING THE NATURE OF THE INTERACTION BETWEEN HUMAN MONOCLONAL
ANTIPHOSPHOLIPID ANTIBODIES AND DOMAIN I OF β-2-GLYCOPROTEIN I
C Pericleous 1 , Y Ioannou 1 , N Lambrianides 1 , P Chen 2 , D Latchman 1 , D Isenberg 1 , A Rahman 1 , I Giles 1 .
1
Department of Medicine, University College London, London, London, United Kingdom; 2 Department of
Medicine, University of California at Los Angeles, Los Angeles, CA, United States
173 LUPUS NEPHRITIS AND THE PODOCYTE
JJ Manson 1 , E Jury 1 , LJ Mason 1 , D D’Cruz 2 , M Saleem 3 , DA Isenberg 1 , A Rahman1.
1
Centre for Rheumatology Research, University College London, London, United Kingdom; 2 The Rayne Institute,
St Thomas’ Hospital, London, United Kingdom; 3 Academic Renal Unit, University of Bristol, Bristol, United
Kingdom
63

174 AN AUDIT OF CARDIOVASCULAR (CVS) RISK FACTOR MONITORING IN PATIENTS WITH SYSTEMIC
LUPUS ERYTHEMATOSIS (SLE) IN A DISTRICT GENERAL HOSPITAL
E Keevil 1 , KP O’Rourke 1 , C Laversuch 1 , S Kyle 1 , J King 1 , T Jewell 1 , L Cooke 1 , L Coward 1 , E Parker 1 , S Kay 1 .
1
Department of Rheumatology, Musgrove Park Hospital, Taunton, Somerset, United Kingdom
175 PREGNANCY OUTCOMES IN SLE IN INDIAN PATIENTS
R Gupta 1 , S Deepanjali 1 , A Kumar 1 , V Dadhwal 2 , SK Agarwal 3 , PK Chaturvedi 4 , RM Pandey 5 .
1
Medicine, All India Institute of Medical Sciences, New Delhi, India; 2 Gynae & Obst., All India Institute of Medical
Sciences, New Delhi, India; 3 Nephrology, All India Institute of Medical Sciences, New Delhi, India; 4 Reproduction
Biology, All India Institute of Medical Sciences, New Delhi, India; 5 Biostatistics, All India Institute of Medical
Sciences, New Dehi, New Delhi, India
176 EPISODIC ISCHAEMIA OF THE HANDS IN A PATIENT ANTIPHOSPHOLIPID SYNDROME AND SLE
M Castelino 1 , N Sathi 1 , D Bulgen 1 , K Over 1 .
1
Rheumatology, Countess of Chester Hospital, Chester, Cheshire, United Kingdom
177 UNDER-REPORTING OF SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) AS A CONTRIBUTORY CAUSE TO
DEATH ON DEATH CERTIFICATES IN SLE PATIENTS
V Toescu 1,3 , CS Yee 1,2,3 , A Prabu 2 , S Bowman 1 , D Situnayake 2 , C Gordon 1,2,3 .
1
Rheumatology, University Hospital Birmingham NHS Trust, Birmingham, United Kingdom; 2 Rheumatology,
Sandwell & West Birmingham Hospitals NHS Trust, Birmingham, United Kingdom; 3 Division of Immunity and
Infection, University of Birmingham, Birmingham, United Kingdom
VASCULITIS
178 ASSOCIATION BETWEEN BONE MARROW B CELL CLONAL EXPANSION AND GLOMERULONEPHRITIS
IN TYPE II MIXED CRYOGLOBULINAEMIA
L Quartuccio, M Fabris, S Sacco, G De Marchi, S De Vita.
1
DPMSC, Rheumatology Clinic, Udine, Italy
179 CLASSIFICATION CRITERIA FOR THE POLYMYALGIC SYNDROME: RESULTS FROM A CONSENSUS
CONFERENCE AND EXTENDED DELPHI SURVEY
B Dasgupta 1 , C Salvarani 2 , M Schirmer 3 , C Crowson 4 , H Maradit-Kremers 4 , E Matteson 4 , Members of the American
College of Rheumatology Work Group for Development of Classification Criteria.
1
Southend University Hospital, Westcliff, Essex, United Kingdom; 2 Arcispedale Santa Maria Nouva, Regio Emelia,
Italy; 3 Allgemeines Krankenhaus der Elisabethianer, Klagenfurt, Austria; 4 Mayo Clinic College of Medicine,
Rochester, United States
180 ROLE OF RITUXIMAB IN REFRACTORY WEGENER’S GRANULOMATOSIS: REAL LIFE EXPERIENCE
IN 4 PATIENTS
A Abhishek 1 , A Pendleton 1 , AC Jones 1 , PC Lanyon 1 .
1
Department of Rheumatology, City Hospital Nottingham, Nottingham, United Kingdom
181 CURRENT EVIDENCE OF FACTORS INFLUENCING REMISSION, RELAPSE, RENAL FAILURE AND
MORTALITY IN PATIENTS WITH SYSTEMIC VASCULITIS. A SYSTEMATIC REVIEW FOR THE EULAR
SYSTEMIC VASCULITIS TASK FORCE
CB Mukhtyar 1 , O Flossmann 2 , B Hellmich 3 , RA Luqmani 1 , EUVAS.
1
Botnar Research Centre, University of Oxford, Oxford, United Kingdom; 2 Department of Nephrology,
Addenbrooke’s Hospital, Cambridge, United Kingdom; 3 Department of Rheumatology, University Hospital of
Schleswig-Holstein, Lubeck, Germany
64

182 A STUDY OF AUTO-ANTIBODIES TO CYCLIC CITRULLINATED PEPTIDE IN A POLYMYALGIA
RHEUMATICA INCEPTION COHORT FROM THE UK PMR OUTCOMES STUDY
B Dasgupta 1 , A Hutchings 2 , J Hollywood 1 , L Nutter 1 , D Lamping 2 , C Pease 3 , K Chakravarty 4 , B Hazleman 5 ,
B Silverman 5 , DGI Scott 6 , E Choy 7 , B Bourke 8 , N Gendi 9 .
1
Rheumatology, Southend University Hospital, Westcliff, Essex, United Kingdom; 2 Health Services Research
Unit, London Scholl of Hygiene & Tropical Medicine, London, United Kingdom; 3 Rheumatology, Leeds General
Infirmary, Leeds, Yorks, United Kingdom; 4 Rheumatology, Haroldwood Hospital, Romford, Essex, United
Kingdom; 5 Rheumatology, Addenbrookes Hospital, Cambridge, Cambridgeshire, United Kingdom;
6
Rheumatology, Norfolk & Norwich University Hospital, Norwich, Norfolk, United Kingdom; 7 Rheumatology, Kings
College Hospital, London, United Kingdom; 8 Rheumatology, St Georges Hospital, Tooting, United Kingdom;
9
Rheumatology, Basildon & Thurrock University Hospital, Basildon, United Kingdom
183 ROLE OF F18-FDG PET-CT SCAN IN DIAGNOSIS AND ASSESSMENT OF DISEASE ACTIVITY OF
TAKAYASU’S ARTERITIS – PRELIMINARY RESULTS
A Kavimandan 1 , R Gupta 1 , R Kumar 2 , A Malhotra 2 , S Sharma 3 , GS Gulati 3 , S Singh 4 .
1
Medicine, All India Institute of Medical Sciences, New Delhi, India; 2 Nuclear Medicine, All India Institute of
Medical Sciences, New Delhi, India; 3 Cardiac Radiology, All India Institute of Medical Sciences, New Delhi,
India; 4 Cardiology, All India Institute of Medical Sciences, New Delhi, India
184 GRANULOMATOUS PROSTATITIS – AN UNUSUAL PRESENTATION OF WEGENER’S
GRANULOMATOSIS
CR Fisher 1 , S MacAdoo 1 , A Rahman 1 , DA Isenberg 1 .
1
Centre for Rheumatology, University College London Hospital, London, United Kingdom
RHEUMATOID ARTHRITIS – CLINICAL ASPECTS
185 ANTIBODIES TO CITRULLINATED VIMENTIN ARE A SPECIFIC AND SENSITIVE MARKER FOR THE
DIAGNOSIS OF RHEUMATOID ARTHRITIS
H Poulsom 1 , PJ Charles 1,2 .
1
Immunology, Hammermsith Hospitals NHS Trust, London, United Kingdom; 2 Kennedy Institute of
Rheumatology, Imperial College, London, United Kingdom
186 THE CONTEMPORARY USE AND PERCEPTION OF THE RHEUMATOID FACTOR BY PRIMARY CARE
PHYSICIANS AND PATIENTS
R Shaban, RG Hull.
1
Rheumatology, Portsmouth Hospitals Trusts, Portsmouth, Hampshire, United Kingdom; 2 Rheumatology,
Portsmouth Hospital Trusts, Portsmouth, Hampshire, United Kingdom
187 A DEVELOPED MULTIDIMENSIONAL HEALTH ASSESSMENT QUESTIONNAIRE: USE FOR STAN-
DARD CLINICAL CARE OF PATIENTS WITH RHEUMATIC DISEASES
Y El Miedany 1 , D Palmer 1 , M El Gaafary 2 .
1
Rheumatology, Darent Valley Hospital, Dartford, United Kingdom; 2 Community, Enviromental and Occupational
Medicine, Ain Shams University, Cairo, Egypt
188 ASSESSING AGREEMENT AND SENSITIVITY TO CHANGE OF TWO INTERNATIONAL RESPONSE
CRITERIA FOR RHEUMATOID ARTHRITIS IN ROUTINE CLINICAL PRACTICE
AK Saha 1 , G Coakley 2 , E Choy 1 .
1
Clinical and Academic Rheumatology, King’s College London, Camberwell, London, United Kingdom;
2
Department of Rheumatology, Queen Elizabeth II Hospital, Woolwich, London, United Kingdom
65

189 AUDIT OF ARMA STANDARDS OF CARE FOR INFLAMMATORY ARTHRITIS: CARDIOVASCULAR RISK
ASSESSMENT
C Crabtree, KM Jordan.
1
Rheumatology, Brighton and Sussex University Hospitals NHS Trust, Brighton, East Sussex, United Kingdom
190 FOOT PROBLEMS ARE MORE PREVALENT IN RHEUMATOID ARTHRITIS (RA) THAN PREVIOUSLY
REPORTED
S Otter 1 , K Lucas 1 , K Springett 2 , A Moore 1 , K Davies 3 , K Walker-Bone 3 .
1
School of Health Professions, University of Brighton, Eastbourne, East Sussex, United Kingdom; 2 School of Health
Professions, Canterbury Christ Church University, Canterbury, Kent, United Kingdom; 3 Rheumatology Dept,
Brighton & Sussex Medical School, Brighton, East Sussex, United Kingdom
191 PREDICTORS OF FURTHER RADIOLOGICAL DAMAGE IN PATIENTS WHO HAVE EROSIVE DISEASE
AFTER FIVE YEARS OF INFLAMMATORY POLYARTHRITIS
M Bukhari, H Naseem, A Barton, D Bunne, DPM Symmons.
1
ARC Epidemiology Unit, University of Manchester, Manchester, United Kingdom
192 USING EXTREMITY MRI IN THE DIAGNOSIS AND MONITORING OF EARLY RA: THE OPTIMAL JOINT
COMBINATION TO BE SCANNED IN CLINICAL PRACTICE
JE Freeston 1 , E Olech 2 , PG Conaghan 1 , P Emery 1 , D Yocum 2 .
1
Academic Unit of Musculoskeletal Disease, University of Leeds, Chapel Allerton Hospital, Leeds, West Yorkshire,
United Kingdom; 2 Rheumatology, University of Arizona, Tucson, AZ, United States
193 AUDIT OF SMOKING AND ATTITUDE TO SMOKING CESSATION IN RHEUMATOID ARTHRITIS
ND McKay, J Hamilton, V Saravanan, C Kelly.
1
Rheumatology, Queen Elizabeth Hospital, Gateshead, Tyne and Wear, United Kingdom
194 SMOKING CAUSES SIGNIFICANT INCREASES OF BASAL METABOLIC RATE IN PATIENTS WITH
RHEUMATOID ARTHRITIS
GS Metsios, A Stavropoulos Kalinoglou, K Douglas, AM Nevill, Y Koutedakis, GD Kitas.
1
Rheumatology, Russell’s Hall Hospital, Dudley Group of Hospitals NHS Trust, Dudley, West Midlands, United
Kingdom; 2 School of Sports, Performing Arts and Leisure, University of Wolverhampton, Wolverhampton, West
Midlands, United Kingdom
195 CHEST INFECTION IN RHEUMATOID ARTHRITIS
AM Salih.
1
Rheumatology, Warrington Hospital, Warrington, Cheshire, United Kingdom
196 CHRONIC KIDNEY DISEASE AMONG PATIENTS WITH RHEUMATOID ARTHRITIS
AM Salih.
1
Rheumatology, Warrington Hospital, Warrington, Cheshire, United Kingdom
197 PREVALENCE AND PREDICTORS OF HYPERTENSION IN RHEUMATOID ARTHRITIS
VF Panoulas 1 , KMJ Douglas 1 , DG Daoussis 1 , PG Nightingale 2 , AGC Paul 1 , GJ Treharne 1 , GD Kitas 1 .
1
Rheumatology, Russells Hall Hospital, Dudley Group of Hospitals, Dudley, West Midlands, United Kingdom;
2
Wellcome Trust Clinical Research Facility, Queen Elizabeth Hospital, Birmingham, West Midlands, United Kingdom
198 DELAY IN PRESENTATION TO PRIMARY CARE PHYSICIANS IS THE MAIN REASON WHY PATIENTS
WITH RHEUMATOID ARTHRITIS ARE SEEN LATE BY RHEUMATOLOGISTS
K Kumar 1 , E Daley 1 , DM Carruthers 1 , RD Situnayake 1 , C Gordon 1 , K Grindulis 1 , CD Buckley 1 , F Khattak 1 , K Raza 1 .
1
Department of Rheumatology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, United
Kingdom
66

199 FOOT PROBLEMS IN RHEUMATOID ARTHRITIS (RA); UNDER-RATED, UNDER-ASSESSED &
UNDER-REFERRED?
S Otter 1 , K Lucas 1 , K Springett 2 , A Moore 1 , K Davies 3 , K Walker-Bone 3 .
1
School of Health Professions, University of Brighton, Eastbourne, East Sussex, United Kingdom; 2 School of
Health Profesions, Canterbury Christ Church Univeristy, Canterbury, Kent, United Kingdom; 3 Rheumatology Dept,
Brighton & Sussex Medical School, Brighton, East Sussex, United Kingdom
200 UPTAKE OF INFLUENZA VACCINATION IN HEALTHCARE WORKERS CARING FOR PATIENTS TAKING
DISEASE MODIFYING ANTI-RHEUMATIC DRUGS AND STEROIDS
R Day 1 , C Kelly 1 , V Saravanan 1 , C Heycock 1 , J Hamilton 1 .
1
Rheumatology Department, Queen Elizabeth Hospital, Gateshead, Tyne and Wear, United Kingdom
201 ANTI-CYCLIC CITRULLINATED PEPTIDE (ANTI-CCP) ANTIBODIES AS INDICATORS OF DISEASE
SEVERITY IN RHEUMATOID ARTHRITIS
A Rezaei 1 , G Firth 1 , K Walker-Bone 2 .
1
Clinical Biochemistry, Brighton & Sussex University Hospitals NHS Trust, Brighton, East Sussex, United
Kingdom; 2 Rheumatology, Brighton & Sussex Medical School, Brighton, East Sussex, United Kingdom
202 PREVALENCE AND PREDICTORS OF RENAL DYSFUNCTION IN RHEUMATOID ARTHRITIS
DG Daoussis 1 , KMJ Douglas 1 , VF Panoulas 1 , IA Antonopoulos 1 , GJ Traharne 1 , PG Nightingale 2 , GD Kitas 1 .
1
Rheumatology, Russell’s Hall Hospital, DGOH, Dudley, Birmingham, West Midlands, United Kingdom;
2
Wellcome Trust, Clinical Research Facility, Queen Elizabeth Hospital, Birmingham, West Midlands, United
Kingdom
203 IS FAILURE TO ACHIEVE A 1.2 REDUCTION IN DAS28 IN THE EARLY MONTHS OF ANTI-TNF ALPHA
THERAPY AN APPROPRIATE CRITERION FOR WITHDRAWING THE TREATMENT IN RA?
MC Greenwood, J Rathi, M Cooney, M Rooney, AJ Hakim, DV Doyle.
1
Academic Rheumatology and Osteoporosis Unit, Whipps Cross University Hospital NHS Trust,
London, United Kingdom
204 DOES MUSCULOSKELETAL ULTRASOUND (MSUS) IMPROVE DIAGNOSIS AND TREATMENT OF
INFLAMMATORY ARTHRITIS IN A DISTRICT GENERAL HOSPITAL?
SE Lane 1 , GP Clunie 1 , RA Watts 1 .
1
Rheumatology, Ipswich Hospital, Ipswich, Suffolk, United Kingdom
205 ATTITUDES OF RHEUMATOLOGISTS TO RAPIDLY PROGRESSING RHEUMATOID ARTHRITIS
IB McInnes 1 .
1
Glasgow Royal Infirmary, Centre for Rheumatic Diseases, University of Glasgow, Glasgow, United Kingdom
206 EZETIMIBE AND SIMVASTATIN REDUCE INFLAMMATION, DISEASE ACTIVITY, AORTIC STIFFNESS
AND IMPROVE ENDOTHELIAL FUNCTION IN RHEUMATOID ARTHRITIS
KM Maki-Petaja 1 , AD Booth 1 , FC Hall 2 , SM Wallace 1 , A Furlong 2 , J Cheriyan 1 , MJ Ashby 1 , CM McEniery 1 ,
J Brown 3 , IB Wilkinson 1 .
1
Clinical Pharmacology Unit, University of Cambridge, Cambridge, Cambs, United Kingdom; 2 Clinical Medicine,
University of Cambridge, Cambridge, Cambs, United Kingdom; 3 Trinity College, University of Cambridge,
Cambridge, Cambs, United Kingdom
67

207 DO PATIENTS WITH DIABETES OR RHEUMATOID ARTHRITIS WHO UNDERGO TOTAL HIP
ARTHROPLASTY HAVE A WORSE OUTCOME COMPARED TO PATIENTS WITH UNCOMPLICATED
OSTEOARTHRITIS?
RS Manhas 4 , H Pandit 1 , A Sabokbar 3 , R Gundle 1 , D Murray 1 , RA Luqmani 2 .
1
Department of Orthopaedic Surgery, Nuffield Orthopaedic Centre, Oxford, United Kingdom; 2 Department of
Rheumatology, Nuffield Orthopaedic Centre, Oxford, United Kingdom; 3 Botnar Research Centre, Oxford, United
Kingdom; 4 Department of Rheumatology, Great Western Hospital, Swindon, United Kingdom
208 SHOULD ANTI CCP ANTIBODIES BE TESTED IN A DISTRICT GENERAL HOSPITAL?
K Yein 2 , L Williamson 1 , EJ Price 1 , DA Collins 1 .
1
Department of Rheumatology, Great Western Hospital, Swindon, Wiltshire, United Kingdom; 2 Department of
Rheumatology, Hereford County Hospital, Hereford, Herefordshire, United Kingdom
209 UPTAKE OF INFLUENZA AND PNEUMOCOCCAL VACCINATION IN PATIENTS ON DISEASE
MODIFYING ANTI RHEUMATIC DRUGS AND TNF BLOCKERS
V Vagadia, M Bridges.
1
Department of Rheumatology, University Hospital of North Tees and Hartlepool, Stockton, Cleveland,
United Kingdom
210 CORRELATES OF SLEEP DISTURBANCE IN RHEUMATOID ARTHRITIS PATIENTS
MJ O’Malley 1 , P Jobanputra 2 .
1
School of Medicine, University of Birmingham, Birmingham, West Midlands, United Kingdom; 2 Department of
Rheumatology, University Hospital Birmingham NHS Trust, Birmingham, West Midlands, United Kingdom
211 TIMING OF CERVICAL SPINE RADIOGRAPHS IN RHEUMATOID ARTHRITIS
SL Westlake, J Taylor, T Cornell, SCM Richards.
1
Department of Rheumatology, Poole Hospital, Poole, Dorset, United Kingdom
212 DISTAL INTERPHALANGEAL JOINT INVOLVEMENT IS NOT AN EXCLUSIVE FINDING OF PSORIATIC
ARTHRITIS
R Scarpa 1 , MA Cimmino 3 , R Peluso 1 , E Soscia 2 , M Atteno 1 , L Costa 1 , DNM Di Minno 1 , S Iervolino 1 , U Balestrieri 1 ,
M Salvatore 2 .
1
Dpt of Clinical and Experimental Medicine, Rheumatology Research Unit - University Federico II, Naples, Italy;
2
National Council of Research, Radiology Unit - Biostructures and Bioimaging Institute University Federico II,
Naples, Italy, Italy; 3 Dpt of Internal Medicine, Rheumatology Unit - University of Genoa, Genoa, Italy
213 10-YEAR ABSOLUTE RISK OF CORONARY HEART DISEASE IN PATIENTS WITH RHEUMATOID
ARTHRITIS
OY Galyutina 1 , MA Stanislavchuk 2 .
1
Rheumatology, Ukrainian State Scientific Reseache Institute of Invalid Rehabilitation, Vinnytsya, Ukraine;
2
Rheumatology, National Medical University, Vinnytsya, Ukraine
214 THE RELATION BETWEEN CLINICALLY DETERMINED DISEASE ACTIVITY, INFLAMMATORY MARKERS
AND ULTRASOUND FINDINGS IN ADULT RHEUMATOID ARTHRITIS
B Hameed 1 , C Heron 2 , J Pilcher 2 , PDW Kiely 1 . 1 Rheumatology, St George’s Healthcare NHS Trust, London, United
Kingdom; 2 Radiology, St George’s Healthcare NHS Trust, London, United Kingdom
215 TWO-YEAR OUTCOME IN A COHORT OF PATIENTS WITH EARLY PERSISTENT INFLAMMATORY
ARTHRITIS: HEALTH STATUS AND DISEASE ACTIVITY
YM El Miedany 1 , D Palmer 1 , M El Gaafary 2 .
1
Rheumatology Department, Darent Valley Hospital, Dartford, Kent, United Kingdom; 2 Community, Enviromental
and Occupational Medicine, Ain Shams University, Cairo, Egypt
68

216 CARDIOVASCULAR RISK IN RHEUMATOID ARTHRITIS: USE OF THE REVISED JOINT BRITISH
SOCIETY GUIDELINES (JBS2) IN A POPULATION OF PATIENTS WITH RHEUMATOID ARTHRIITS IN
SECONDARY CARE
FA Borg, CA Borysiewicz, SP McAdoo, S Kuzmanowski, S Moore, AA Olaleye, VH Morris.
1
Centre for Rheumatology, University College London Hospital, London, United Kingdom
217 DEPRESSION AND ANXIETY CONFOUND ASSESSING DISEASE ACTIVITY IN RHEUMATOID
ARTHRITIS
TJ Worrall 1 , E Haddow 1 , M Bukhari 2 .
1
4th Year Medical Student, University of Liverpool, Liverpool, United Kingdom; 2 Rheumatology, Royal Lancaster
Infirmary, Lancaster, Lancashire, United Kingdom
218 AUDIT OF DAS 28 AS A PREDICTOR OF TREATMENT CHANGE IN RHEUMATOID ARTHRITIS
SY Tan, S Smith, A Strang, KD Morley, T Pullar, B Galarraga.
1
Rheumatic Diseases Unit, Ninewells Hospital and Medical School, Dundee, Scotland, United Kingdom
219 ANTIBODY RESPONSE TO THE 23-VALENT PNEUMOCOCCAL POLYSACCARIDE VACCINATION IN
RHEUMATOID ARTHRITIS: THE EFFECTS OF METHOTREXATE AND BIOLOGICAL THERAPY IN A
SECONDARY CARE COHORT
GJ Treharne 1,2 , VE Burns 3 , DL Mitton 2 , N Erb 2 , GD Kitas 1,4,2 .
1
School of Psychology, University of Birmingham, Birmingham, United Kingdom; 2 Department of Rheumatology,
Dudley Group of Hospitals NHS Trust, Dudley, West Midlands, United Kingdom; 3 School of Sport and Exercise
Sciences, University of Birmingham, Birmingham, United Kingdom; 4 Research Institute in Healthcare Science,
University of Wolverhampton, Wolverhampton, United Kingdom
220 DO SIMPLE INSOLES REDUCE PLANTAR PRESSURE AND INCREASE FOREFOOT COMFORT IN
PATIENTS WITH RHEUMATOID ARTHRITIS?
SK Gilbard 1 , KR MacKay 1 , NJ Viner 1 .
1
Dept of Rheumatology, Torbay Hospital, Torquay, Devon, United Kingdom
221 FOREFOOT BURSITIS IN PATIENTS WITH RHEUMATOID ARTHRITIS: IS THERE A LINK TO PEAK
PLANTAR PRESSURES?
CJ Bowen 1 , M Backhouse 1 , J Burridge 1 , NK Arden 2 .
1
School of Health Professions and Rehabilitation Sciences, University of Southampton, Southampton,
Hampshire, United Kingdom; 2 MRC Epidemiology Resource Centre, University of Southampton, Southampton,
Hampshire, United Kingdom
222 GEOGRAPHICAL VARIATIONS IN THE CLINICAL PHENOTYPE OF RHEUMATOID ARTHRITIS:
COMPARING DISEASE ACTIVITY IN SAUDI ARABIA WITH ENGLAND
D Houssein 1,3 , B Khoshaba 1 , DL Scott 1,2 .
1
Department of Rheumatology, Kings College London School of Medicine, London, United Kingdom;
2
Department of Rheumatology, Kings College Hospital, London, United Kingdom; 3 Arthritis Clinic, Centre for
Rheumatism, Jeddah, Saudi Arabia
223 WHAT RHEUMATOLOGISTS REALLY THINK ABOUT PATIENTS WITH SPONDYLOARTHRITIS: 2006
SURVEY RESULTS FROM EUROPE AND CANADA
F Van den Bosch 1 .
1
Rheumatology, University Hospital Ghent, Ghent, Belgium
224 REACTIVE PERFORATING COLLAGENOSIS AND RHEUMATOID DISEASE; A LINK?
S Agarwal, BE Bourke, PD Kiely.
1
Department of Rheumatology, St. George’s Hospital NHS Trust, London, United Kingdom
69

225 FATIGUE IN RHEUMATOLOGY PATIENTS IS INDEPENDANT OF PAIN, AGE AND ANAEMIA
J Robertson 1 , S Alder 1 , G Roberts 2 , C McGregor 2 , MM Gordon 2 , J Hunter 2 .
1
Medical School, University of Glasgow, Glasgow, United Kingdom; 2 Department of Rheumatology, Gartnavel
General Hospital, Glasgow, United Kingdom
226 IMPACT OF GP QUALITY AND OUTCOMES FRAMEWORK (QOF) SYSTEM ON CARDIOVASCULAR RISK
MONITORING IN RHEUMATOID ARTHRITIS PATIENTS
DJ Armstrong, L Gettings, AJ Chuck, SJ Hailwood, N Kumar.
1
Rheumatology, University Hospital of North Durham, Durham, Co Durham, United Kingdom
227 ARE WE DOCUMENTING CARDIOVASCULAR RISK IN PATIENTS WITH RHEUMATOID ARHRITIS?
A MULTI-CENTRE AUDIT
CR Holroyd 1 , AM Scott-Russell 1 , ZA Cole 2 , V Rajagopal 3 .
1
Rheumatology, North Hampshire Hospital, Basingstoke, Hampshire, United Kingdom; 2 Rheumatology, Queen
Alexandra Hospital, Portsmouth, Hampshire, United Kingdom; 3 Rheumatology, Southampton General Hospital,
Southampton, Hampshire, United Kingdom
228 CARDIOVASCULAR RISK AND RHEUMATOID ARTHRITIS: WHAT DO GENERAL PRACTITIONERS
KNOW AND DO?
RF Mascarenhas, HJ Smallwood, KR Mackay, NJ Viner.
1
Rheumatology Department, Torbay Hospital, Torquay, Devon, United Kingdom
229 ARE WE FOCUSING THE USE OF ANTI CYCLICAL CITRULINATED PEPTIDE ANTIBODIES TESTS IN
PATIENTS WITH RHEUMATOID ARTHRITIS?
ECS Wong 1 , K Murphy 2 , A Bradlow 2 .
1
Rheumatology Department, Nuffield Orthopaedic Centre, Oxford, Oxfordshire, United Kingdom; 2 Rheumatology
Department, Royal Berkshire Hospital, Reading, Berkshire, United Kingdom
230 HOW FUNCTION & STRUCTURE CHANGE WITH TIME IN EARLY RHEUMATOID ARTHRITIS (RA) –
A LONGITUDINAL ANALYSIS FROM THE ERAS COHORT
J Dixey 1 , C Emmett 2 , C Sollymossy 3 , P Jones 2 , P Williams 3 , A Young 3 .
1
Rheumatology, Robert Jones & Agnus Hunt Orthopaedic Hospital, Oswestry, United Kingdom; 2 Dept. of
Mathamatics, Keele University, Keele, United Kingdom; 3 ERAS, On Behalf of the Early Rheumatoid Arthritis Study,
St Albans, United Kingdom
231 POST INJECTION ADVICE: SHOULD WE ALLOW PATIENTS TO DRIVE HOME?
RF Mascarenhas, HJ Smallwood, NJ Viner, KR Mackay.
1
Rheumatology, Torbay District General Hospital, Torquay, Devon, United Kingdom
232 TEACHING YOUNG GUNS OLD TRICKS: CAN RELIABILITY OF DAS 28 SCORES BE DEVELOPED IN A
SINGLE SESSION?
CE Armitage 1 , I Atchia 1,2 , F Birrell 1,2,3 .
1
Rheumatology, Northumbria Healthcare NHS Trust, Northumbria, United Kingdom; 2 Musculoskeletal Research
Group, Newcastle University, Newcastle upon Tyne, United Kingdom; 3 Musculoskeletal Unit, Freeman Hospital,
Newcastle upon Tyne, United Kingdom
233 THE LOCAL AND SYSTEMIC CONSEQUENCES OF GLUCOCORTICOID GENERATION IN SYNOVIUM
RS Hardy 1 , EH Rabbitt 1 , A Filer 2 , M Hewison 4 , PM Stewart 1 , K Raza 2 , CD Buckley 2 , MS Cooper 1 .
1
Division of Medical Sciences, University of Birmingham, Birmingham, West Midlands, United Kingdom;
2
Rheumatology, University of Birmingham, Birmingham, West Midlands, United Kingdom; 3 Academic Section of
Musculoskeletal Disease, University of Leeds, Leeds, West Yorkshire, United Kingdom; 4 Division of Endocrinology,
Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA, United States
70

234 THE DAS28 IS INFLUENCED BY BOTH THE PHYSICAL AND MENTAL HEALTH DOMAINS OF THE
SHORT FORM 36 IN RHEUMATOID ARTHRITIS
M Samaranayake 1 , E Haddow 2 , T Worrall 2 , M Bukhari 1 .
1
Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom; 2 4th Year Medical Student, University of
Liverpool, Liverpool, United Kingdom
235 EARLY RHEUMATOID ARTHRITIS NETWORK (ERAN) AUDIT OF ACCESS TO RHEUMATOLOGY
SERVICES AND DRUG TREATMENT FOR ELDERLY PATIENTS WITH RA COMPARED WITH YOUNGER
PATIENTS
R Williams 1 , K Blunn 1 , W Garwood 3 , C Mayes 3 , A Robottom 2 , A Young 3 .
1
Rheumatology, The County Hospital, Hereford, United Kingdom; 2 Patient Representative, ERAN Audit
Committee Member, Oxford, United Kingdom; 3 On Behalf of ERAN, The Early Rheumatoid Arthritis Network,
Herts, United Kingdom
236 NEUROLOGICAL ADVERSE EFFECTS ASSOCIATED WITH ANTI-TNF THERAPY
HA Ali 1 , S Shamin, M Al-Bayati, A Pace.
1
Rheumatology, New Cross Hospital, Wolverhampton, West Midland, United Kingdom; 2 Rheumatology, New
Cross Hospital, Wolverhampton, West Midland, United Kingdom; 3 Rheumatology, New Cross Hospital,
Wolverhampton, West Midland, United Kingdom
237 RHEUMATOID ARTHRITIS ASSOCIATED CO-MORBIDITIES: ASSESSMENT AND TREATMENT
ADVISE VIA NURSE LED CLINICS
L McGregor 2 , N Cheshire 1 , G Mackle 1 , E McIvor 1 , H Wilson 1 , A McEntegart 1 .
1
Rheumatology Department, Stobhill Hospital, Glasgow, United Kingdom; 2 Rheumatology Department, Wishaw
General Hospital, Wishaw, United Kingdom
238 EVIDENCE IN FAVOUR OF FIBROMYALGIC RHEUMATOID ARTHRITIS: HIGH TRIGGER POINT
COUNTS AND FATIGUE SCORES INDICATE A DIFFERENT CLINICAL PHENOTYPE
LC Pollard, DL Scott.
1
Academic Department of Rheumatology, King’s College London School of Medicine at Guy’s, King’s College
and St Thomas’ Hospitals, London, United Kingdom
239 SUSTAINED EFFICACY ALONG WITH IMPROVEMENTS IN DISEASE ACTIVITY SCORE 28 (DAS28)
AND PATIENT (Pt)-REPORTED OUTCOMES (PROs) WITH ABATACEPT (Aba) IN RHEUMATOID
ARTHRITIS (RA) Pts WITH AN INADEQUATE RESPONSE TO ANTI-TUMOR NECROSIS FACTOR (TNF)
THERAPY: THE LONG-TERM EXTENSION (LTE) OF THE ATTAIN TRIAL
M Dougados 1 , M Schiff 2 , M Luggen 3 , JC Becker 4 , R Aranda 4 , T Li 5 , T McCann 6 , N Schmidely 7 , M LeBars 7 ,
J Sibilia 8 , MC Genovese 9 .
1
Department of Rheumatology B, Hopital Cochin, Rene Descartes University, Paris, France; 2 Clinical Research
Unit, Denver Arthritis Clinic, Denver, CO, United States; 3 University of Cincinnati Medical Center, Cincinnati, OH,
United States; 4 Global Clinical Research, Immunology, Bristol-Myers Squibb, Princeton, NJ, United States;
5
Outcomes Research, Bristol-Myers Squibb, Princeton, NJ, United States; 6 Global Biometric Sciences, Bristol-
Myers Squibb, Princeton, NJ, United States; 7 Bristol-Myers Squibb, Rueil-Malmaison, France; 8 Rheumatology
Department and Immunopathology Laboratory, Centre Hospitalier Universitaire Louis Pasteur University,
Strasbourg, France; 9 Department of Rheumatology, Stanford University, Palo Alto, CA, United States
240 DAMAGE IN RHEUMATOID ARTHRITIS ASSESSED BY A NOVEL CLINCIAL SCORE – NUMBER OF
DAMAGED JOINTS
N Haroon 1 , A Aggarwal 1 , A Lawrence 1 , V Aggarwal 1 , R Misra 1 .
1
Department of Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar
Pradesh, India
71

241 FREQUENCY OF CLINICAL REMISSION AND RADIOGRAPHIC PROGRESSION IN EARLY RHEUMATOID
ARTHRITIS (RA): RESULTS FROM AN INCEPTION COHORT OF EARLY RA PATIENTS
KS Jayakumar 1 , C Sollymossy 1 , J Dixey 2 , N Cox 3 , A Young 1 .
1
Rheumatology, St Albans City Hospital, On Behalf of ERAS, Herts, United Kingdom; 2 Rheumatology, Robert Jones
& Agnus Hunt Orthopaedic Hospital, Oswestry, Shropshire, United Kingdom; 3 Rheumatology, Royal Hampshire
County Hospital, Winchester, Hants, United Kingdom
242 RADIOGRAPHIC DISEASE PROGRESSION DESPITE CLINICAL REMISSION IN EARLY RHEUMATOID
ARTHRITIS (RA): EARLY RA STUDY (ERAS)
KS Jayakumar 1 , C Sollymossy 1 , J Dixey 2 , S Stafford 3 , A Young 1 .
1
Rheumatology, St Albans City Hospital, On Behalf of ERAS, Herts, United Kingdom; 2 Rheumatology, Robert Jones
& Agnus Hunt Orthopaedic Hospital, Oswestry, Shropshire, United Kingdom; 3 Rheumatology, Royal Hampshire
County Hospital, Winchester, Hants, United Kingdom
243 CARDIOVASCULAR RISK IN RHEUMATOID ARTHRITIS (RA). A REGIONAL AUDIT
G Koduri 1 , J Griffin 1 , H Sinclair 1 , C Kelsey 1 , M Percy 1 , F Yuksel 1 , A Young 1 .
1
Rheumatology, North West Thames Regional Audit Group, Herts, United Kingdom
HEALTH SERVICES RESEARCH, ECONOMICS AND OUTCOMES RESEARCH
244 VIEWS AND GOALS OF DOCTORS AND NURSES IN THEIR CONSULTATIONS WITH PATIENTS WHO
LIVE WITH RHEUMATOID ARTHRITIS
H Lempp 1 , DL Scott 2 , GH Kingsley 3 .
1
Academic Department of Rheumatology, King’s College London School of Medicine, London, United Kingdom;
2
Department of Rheumatology, King’s College London NHS Trust, London, United Kingdom; 3 Department of
Rheumatology, University Hospital Lewisham NHS Trust, London, United Kingdom
245 THE PREVALENCE OF OSTEOPOROSIS IS INFLUENCED BY THE DISTANCE PATIENTS TRAVEL FOR A
BONE DENSITY (DEXA) SCAN
M Bukhari, EF Wood, CM Greenbank, JP Halsey.
1
Rheumatology, Royal Lancaster Infirmary, Lancaster, Lancashire, United Kingdom
246 VACCINATE YOUR PATIENTS – AN AUDIT FROM PRIMARY CARE
RA Watts 1 , S Rudland 2 .
1
Department of Rheumatology, Ipswich Hospital NHS Trust, Ipswich, Suffolk, United Kingdom; 2 StowHealth,
Stowmarket, Suffolk, United Kingdom
247 GENERAL PRACTITIONERS AND THE PROVISION OF COMMUNITY RHEUMATOLOGY – PRESENT
AND FUTURE
JHM Lee 1 , S Ellis 1 .
1
Rheumatology, Lister Hospital, Stevenage, Hertfordshire, United Kingdom
248 A PROSPECTIVE AUDIT OF NSAID PRESCRIBING IN A DISTRICT GENERAL TEACHING HOSPITAL
AJ Thake 1 , C Phipps 1 , M Bukhari 1 , S Alaib 1 .
1
Rheumatology Department, Royal Lancaster Infirmary, Lancaster, Lancashire, United Kingdom
249 MUSCULOSKELETAL ULTRASOUND (MSUS) CAN BE USED SUCCESSFULLY TO DETECT SUBCLINICAL
SYNOVITIS/TENOSYNOVITIS AND EARLY EROSIONS IN A DISTRICT GENERAL HOSPITAL
SE Lane 1 , GP Clunie 1 , RA Watts 1 .
1
Rheumatology, Ipswich Hospital NHS Trust, Ipswich, Suffolk, United Kingdom
72

250 STRATEGIES USED TO IMPROVE RECRUITMENT TO A CLINICAL TRIAL OF INTRAMUSCULAR
METHYLPREDNISOLONE IN VERY EARLY INFLAMMATORY POLYARTHRITIS
MJ McCoy 1 , NE Dale 1 , AB Hassell 2 , HA Bird 3 , DPM Symmons 1 .
1
Arthritis Research Campaign Epidemiology Unit, The University of Manchester, Manchester, United Kingdom;
2
Staffordshire Rheumatology Centre, Haywood Hospital, Stok e-on-Trent, Staffordshire, United Kingdom;
3
Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, West Yorkshire, United Kingdom
251 ASSESSING CHANGE IN PHYSICAL FUNCTION FOR PEOPLE WITH MUSCULOSKELETAL
SYMPTOMS
SA Ayis, P Dieppe.
1
Social Medicine, Canynge Hall, Whiteladies Road, MRC HSRC, Bristol, United Kingdom
252 ADALIMUMAB-TREATED PATIENTS WITH LONG-STANDING RHEUMATOID ARTHRITIS (RA)
DECREASE THEIR RESOURCE UTILIZATION DURING THE COURSE OF LONG-TERM TREATMENT
T Mittendorf 1 , BM Dietz 2 , JM von der Schulenberg 1 , U Benter 3 , M Cifaldi 4 , R Sterz 2 .
1
University of Hannover, Hannover, Germany; 2 Abbott GmbH and Co KG, Ludwigshafen, Germany; 3 Kendle
International, Inc., Munich, Germany; 4 Abbott, Abbott Park, IL, United States
253 IMPROVED PHYSICAL FUNCTIONING AND WORK PRODUCTIVITY IN ANKYLOSING SPONDYLITIS
(AS) PATIENTS WHO WERE TREATED WITH ADALIMUMAB — ATLAS TRIAL RESULTS
D van der Heijde 1 , P Wordsworth 2 , MP Luo 3 , PJ Mease 4 , J Reveille 5 , H Zeidler 6 , M Breban 7 , R Westhovens 8 ,
JJ Chmiel 3 , N Chen 3 , R Wong 9 , J Davis 10 .
1
University Hospital Maastricht, Maastricht, Netherlands; 2 Nuffield Orthopaedic Centre, Oxford, United Kingdom;
3
Abbott, Abbott Park, IL, United States; 4 Swedish Medical Center, Seattle, WA, United States; 5 The University
of Texas Health Science Center, Houston, TX, United States; 6 Medizinische Hochschule, Hannover, Germany;
7
Hôpital Ambroise Paré, Boulogne-Billancourt, France; 8 UZ Gasthuisberg, Leuven, Belgium; 9 Abbott, Parsipanny,
NJ, United States; 10 University of California, San Francisco, San Francisco, CA, United States
254 PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS SHOW CLINICAL RESPONSE BY DAY 1 WHEN
TAKING ADALIMUMAB — RESULTS FROM THE HUMIRA EFFICACY RESPONSE OPTIMIZATION
(HERO) STUDY
F Wolfe 1 , K Michaud 1 , T Pincus 2 , JD Kent 3 , AL Pangan 3 .
1
National Data Bank for Rheumatic Diseases, Wichita, KS, United States; 2 Vanderbilt University, Nashville, TN,
United States; 3 Abbott, Abbott Park, IL, United States
255 SETTING UP A RHEUMATOLOGY PATIENT FOLLOW-UP SPREADSHEET. HOW TO DO IT, HOW LONG
DOES IT TAKE, WHAT INFORMATION CAN IT PROVIDE?
E Keevil 1 , KP O’Rourke 1 , C Laversuch 1 , S Kyle 1 , J King 1 , T Jewell 1 , L Cooke 1 , L Coward 1 , E Parker 1 , S Kay 1 .
1
Department of Rheumatology, Musgrove Park Hospital, Taunton, Somerset, United Kingdom
256 RHEUMATOLOGY RESEARCHERS’ AWARENESS OF RESEARCH GOVERNANCE REQUIREMENTS
LJ Kay 1 , Northern Deanery RATS 2 .
1
Department of Rheumatology, Freeman Hospital, Newcastle upon Tyne, Tyne & Wear, United Kingdom;
2
Rheumatology Training Programme, Postgraduate Medical Institute, Northern Deanery, United Kingdom
257 DOCUMENTATION OF ANTI-TNF THERAPY IN PRIMARY CARE HEALTH RECORDS
EM Wise 1,2,3 , C Burdon 4 , K Nicholl 1 , NS Booth 5 , J Dickson 6 , LJ Kay 1,3 .
1
Musculoskeletal Unit, Freeman Hospital, Newcastle upon Tyne, United Kingdom; 2 Belmont Surgery, Durham,
County Durham, United Kingdom; 3 Musculoskeletal Research Group, Newcastle University, Newcastle upon
Tyne, United Kingdom; 4 Roseworth Avenue Surgery, Gosforth, Newcastle upon Tyne, United Kingdom; 5 Primary
Healthcare, Specialist Group, British Computer Society, United Kingdom; 6 Primary Care, Rheumatology Society,
Northallerton, United Kingdom
73

258 ECONOMIC BENEFITS OF ETANERCEPT FOLLOWING ANTI-TNF TREATMENT IN PATIENTS WITH
RHEUMATOID ARTHRITIS: AN ANALYSIS USING TEMPO DATA
M Taylor 1 , P Trueman 1 , AV Reynolds 2 , P Conway 2 .
1
York Health Economics Consortium, University of York, York, United Kingdom; 2 Scientific Affairs, Wyeth
Pharmaceuticals, Maidenhead, Berkshire, United Kingdom
259 IMPROVING PATIENT SAFETY; REDUCING MEDICATION ERRORS THROUGH ACCEPTABLE,
ACCESSIBLE MEDICATION PACKAGING
RA Hughes 1 , AJ Carr 2 , M Carr 1 , M Walsh 1 .
1
Rheumatology, Ashford and St Peter’s Hospitals NHS Trust, Chertsey, Surrey, United Kingdom; 2 Academic
Rheumatology, Nottingham University, Nottingham, Notts, United Kingdom
260 TRENDS IN TRADITIONAL NON STEROIDAL ANTI-INFLAMMATORY DRUG (NSAID) AND COX-2
INHIBITOR (COX 2) USE IN A RHEUMATOLOGY OUTPATIENT DEPARTMENT (ROPD) AND AN
AUDIT OF COMPLIANCE WITH THE EUROPEAN MEDICINES AGENCY (EMEA) GUIDELINES FOR USE
OF COX-2
SC Earl 1 , FC McCrae 2 , AL Thomas 2 , RG Hull 2 , MR Shaban 2 , JM Ledingham 2 .
1
Rheumatology Department, North Hampshire Hospital, Basingstoke, Hants, United Kingdom; 2 Rheumatology
Department, Queen Alexandra Hospital, Portsmouth, Hants, United Kingdom
261 THE COST OF JUVENILE IDIOPATHIC ARTHRITIS (JIA): OBTAINING PATIENT-BASED COSTS DURING
THE FIRST YEAR OF DIAGNOSIS
J Thornton 1 , RA Elliott 2 , M Lunt 1 , DM Ashcroft 2 , E Baildam 3 , H Foster 4 , J Davidson 5 , J Gardner-Medwin 5 ,
MW Beresford 3 , DPM Symmons 1 , W Thomson 1 .
1
Arthritis Research Campaign Epidemiology Unit, University of Manchester, Manchester, United Kingdom; 2 School
of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, United Kingdom; 3 Department
of Rheumatology, Royal Liverpool Children’s Hospital, Liverpool, United Kingdom; 4 Department of Rheumatology,
Medical School, Newcastle, United Kingdom; 5 Department of Child Health, Royal Hospital for Sick Children,
Glasgow, United Kingdom
262 SWITCHING ANTI TNF TREATMENT: WHAT DO PATIENTS THINK OF BEING OFFERED A CHOICE?
KS Mills 1 , AAM Nicol 2 , M Somerville 1 , N Healey 2 , RD Smith 2 , DGI Scott 1 . 1 Rheumatology Department, Norfolk and
Norwich University Hospital, Norwich, Norfolk, United Kingdom; 2 School of Medicine, Health Policy and Practice,
University of East Anglia, Norwich, Norfolk, United Kingdom
263 CHANGING FACE OF RHEUMATOLOGY OUTPATIENT SERVICES
LM Thomas 1 , M Fletcher 2 , FC McCrae 2 , AL Thomas 2 , RG Hull 2 , MR Shaban 2 , JM Ledingham 2 .
1
Rheumatology Department, MDHU Portsmouth, Portsmouth, Hampshire, United Kingdom; 2 Rheumatology
Department, Queen Alexandra Hospital, Portsmouth, Hampshire, United Kingdom
264 EVALUATION OF PATIENT EMPLOYMENT ISSUES WITHIN AN OCCUPATIONAL THERAPY
RHEUMATOLOGY OUT-PATIENT SERVICE
AL Clifton 1 , K McAlarey 2 , L Manson 3 , J McQueen 4 .
1
Occupational Therapy, Inverclyde Royal Hospital, Greenock, United Kingdom; 2 Occupational Therapy, Victoria
Infirmiry, Glasgow, United Kingdom; 3 Occupational Therapy, Southern General Hospital, Glasgow, United Kingdom;
4
Occupational Therapy, Southern General Hospital, Glasgow, United Kingdom
74

265 “TO SWITCH OR NOT TO SWITCH. THAT IS THE QUESTION.” AN ANALYSIS OF PATIENTS
OPPORTUNITY TO CHANGE THEIR ANTI TNF THERAPY FROM INTRAVENOUS INFUSIONS TO SUB
CUTANEOUS INJECTIONS EVEN WHEN RESPONSE WAS GOOD
MF Somerville 1 , A Nichol 2 , K Mills 1 , N Healy 2 , A Brooksby 2 , DG Scott 1 .
1
Rhuematology Department, Norfolk & Norwich University Hospital, Norwich, Norfolk, United Kingdom; 2 Health
Policy and Practice, University of East Anglia, Norwich, Norfolk, United Kingdom
266 A PRIMARY CARE AUDIT OF THE ARMA STANDARDS OF CARE IN OSTEOARTHRITIS
L Davies 1 , JP Halsey 2 , M Bukhari 2 .
1
Rosebank Surgery, Morecambe Bay PCT, Lancaster, Lancashire, United Kingdom; 2 Rheumatology, Royal
Lancaster Infirmary, Lancaster, Lancashire, United Kingdom
267 MAPPING THE PATIENT’S JOURNEY WITH RHEUMATOID ARTHRITIS. ARE STANDARDS OF CARE
BEING MET AND WHAT ARE THE COSTS TO THE INDIVIDUAL AND HEALTHCARE PROVIDERS?
SM Oliver 1 , A Bosworth 2 , Advisory Board 2 .
1
Rheumatology, Royal College of Nursing, London, United Kingdom; 2 National Rheumatoid Arthritis Society,
National Rheumatoid Arthritis Society, Maidenhead, Berkshire, United Kingdom
268 COMPARISON OF REFERRAL TIMES FOR MANAGEMENT OF EARLY RHEUMATOID ARTHRITIS:
ERAN VS A PARTICIPATING CENTRE
A Coulson 1 , S Nagasayi 1 , C Mayes 2 , ERAN Members 2 .
1
Department of Rheumatology, WithyBush General Hospital, Haverfordwest, Pembrokeshire, United Kingdom;
2
ERAN,Rheumatology Department, St. Albans City Hospital, St. Albans, Hertfordshire, United Kingdom
269 PATIENT SATISFACTION SURVEY OF RHEUMATOLOGY OUTPATIENT SERVICES IN WALES
C Rhys-Dillon 1 , H Evans 2 .
1
Department of Rheumatology, Royal Glamorgan Hospital, Llantrisant, Rhondda Cynon Taf, United Kingdom;
2
Policy and Campaigns Manager, Arthritis Care, Cardiff, Wales, United Kingdom
270 CHANGES IN PRIMARY CARE CONSULTATION RATES FOR MUSCULOSKELETAL CONDITIONS:
1991-2001
AM Clarke 1 , K Jordan 2 , MA Barley 3 , DM Fleming 3 , PR Croft 2 , DPM Symmons 1 .
1
Arthritis Research Campaign Epidemiology Unit, The University of Manchester, Manchester, United Kingdom;
2
Primary Care Musculoskeletal Research Centre, Keele University, Keele, United Kingdom; 3 Birmingham
Research Unit, Royal College of General Practitioners, Birmingham, United Kingdom
271 AN AUDIT OF THE TRIAGE AND MANAGEMENT OF RHEUMATOLOGY (Rh) REFERRALS TO TIER 2
(T2) IN CENTRAL MANCHESTER
P Shah 1 , J Fowler 2 , B Nanavati 2 , YA Ahmad 1 .
1
Department of Rheumatology, Central Manchester and Manchester Children’s University Hospitals,
Manchester, United Kingdom; 2 Tier 2, Longsight Health Centre, Manchester, United Kingdom
272 KEEN TO LIVE UNTIL I DIE: PATIENTS PERSPECTIVES OF THE IMPACT OF ANTI TNF THERAPY ON
THEIR QUALITY OF LIFE
KS Mills 1 , AAM Nicol 2 , M Somerville 1 , N Healey 2 , RD Smith 2 , DGI Scott 1 .
1
Rheumatology Department, Norfolk and Norwich University Hospital, Norwich, Norfolk, United Kingdom;
2
School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, Norfolk, United Kingdom
273 MEASUREMENT OF eGFR (MDRD) FOR ESTIMATION OF RENAL FUNCTION IN RHEUMATOLOGY
PATIENTS STARTED ON CICLOSPORIN AND COMPARISON WITH CrCl
HRV Reddy 1 , S McCann 2 , VE Abernethy 1 , MP Lynch 1 , AR Clewes 1 , R Wiswell 1 , JK Dawson 1 .
1
Rheumatology, St Helens Hospital, Merseyside, United Kingdom; 2 Clinical Biochemistry, St Helens Hospital,
Merseyside, United Kingdom
75

274 IMPACT OF NEW GUIDELINES FOR CHRONIC KIDNEY DISEASE ON RHEUMATOLOGICAL PRACTICE:
FINANCIAL AND WORKLOAD IMPLICATIONS
EJ Coulson, CA Kelly, JD Hamilton, V Saravanan.
1
Department of Rheumatology, Queen Elizabeth Hospital, Gateshead, United Kingdom
275 PRE-TREATMENT TPMT TESTING IN RHEUMATOLOGY
EA Fargher 1,2 , K Payne 1,2 , KJ Tricker 1,2 , W Newman 2,3 , IN Bruce 4,5 .
1
Nowgen, The North West Genetics Knowledge Park, Manchester, United Kingdom; 2 Academic Unit of Clinical
Genetics, University of Manchester, Manchester, United Kingdom; 3 Department of Medical Genetics, Central
Manchester and Manchester Childres University Hospitals NHS Trust, Manchester, United Kingdom; 4 ARC
Epidemiology Unit, University of Manchester, Manchester, United Kingdom; 5 Rheumatism Research Centre,
Central Manchester and Manchester Childrens University Hospitals NHS Trust, Manchester, United Kingdom
276 THE POTENTIAL IMPACT OF THE MUSCULOSKELETAL FRAMEWORK ON RHEUMATOLOGY SERVICES
J Galloway 2 , M Samaranayake 1 , W Dodds 1 , W Mitchell 2 , M Bukhari 1 , J Halsey 1 .
1
Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom; 2 Rheumatology, Furness General Hospital,
Barrow in Furness, United Kingdom
277 SPECIALIST INTERVENTIONS IN THE RHEUMATOLOGY OUTPATIENTS CLINIC
MC Wray, FM Pollock, GD Wright.
1
Rheumatology, Royal Group of Hospitals, Belfast, N. Ireland, United Kingdom
278 COST EFFECTIVENESS IN DGH PRACTICE OF antiCCP TESTS IN RF POSITIVE PATIENTS WITH
DIAGNOSTIC DILEMMA
RC Campbell, A Leak.
1
Rheumatology, Queen Elizabeth Queen Mother Hospital, Margate, Kent, United Kingdom
279 AUDIT SURVEY OF PATIENT SATISFACTION OF TIER 2 SERVICE IN CENTRAL MANCHESTER
P Shah 1 , J Fowler 2 , Y Ahmad 1 .
1
Department of Rheumatology, Central Manchester and Manchester Children’s University Hospitals, Manchester,
United Kingdom; 2 Tier 2, Longsight Health Centre, Manchester, United Kingdom
280 CRITICAL APPRAISAL OF THE BRITISH THORACIC SOCIETY (BTS) GUIDELINES FOR ASSESSING RISK
OF TUBERCULOSIS IN PATIENTS ABOUT TO START A TNFα INHIBITOR
A Price-Forbes 1 , A Fry-Smith 2 , D Thickett 3 , P Jobanputra 4 .
1
Rheumatology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, West Midlands, United
Kingdom; 2 Public Health, University of Birmingham, Birmingham, West Midlands, United Kingdom; 3 Senior Lecturer
and Respiratory Consultant, Lung Investigation Unit, University of Birmingham and Selly Oak Hospital, University
Hospitals Birmingham Foundation Trust, Birmingham, West Midlands, United Kingdom; 4 Rheumatology, Selly Oak
Hospital, University Hospitals Birmingham Foundation Trust, Birmingham, West Midlands, United Kingdom
281 PATIENT CHOICE PRIOR TO INITIATING ANTI-TNF TREATMENT: WHAT DO THE PATIENTS THINK?
AAM Nicol 1 , KS Mills 2 , N Healey 1 , RD Smith 1 , M Somerville 2 .
1
School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, Norfolk, United Kingdom;
2
Department of Rheumatology, Norfolk and Norwich University Hospital, Norwich, Norfolk, United Kingdom
282 EXERCISE TAKEN BY RHEUMATOLOGY PATIENTS; SOME BUT NOT NEAR ENOUGH!
KT Yein 1 , EJ Price 2 , DA Collins 2 , L Williamson 2 .
1
Rheumatology, The County Hospital, Hereford, Herefordshire, United Kingdom; 2 Rheumatology, Great Western
Hospital, Swindon, Wiltshire, United Kingdom
76

283 CHANGES IN DISTRESS AND HEALTH BELIEFS IN PEOPLE WITH CHRONIC LOW BACK PAIN
FOLLOWING DIFFERENT KINDS OF PHYSIOTHERAPY
DJ Critchley 1 , CJ Dore 2 , S Noonan 3 , RH Jones 4 , MV Hurley 1 .
1
Academic Department of Physiotherapy, King’s College London, London, United Kingdom; 2 Clinical Trials Unit,
Medical Research Council, London, United Kingdom; 3 Physiotherapy Department, Guy’s and St Thomas’
Hospitals, London, United Kingdom; 4 School of Medicine, King’s College London, London, United Kingdom
284 CO-PROXAMOL: WHERE HAVE ALL THE PATIENTS GONE?
L Ottewell 1 , DJ Walker 2 .
1
Department of Rheumatology, Sunderland City Hospital, Sunderland, United Kingdom; 2 Musculoskeletal Unit,
Freeman Hospital, Newcastle-upon-Tyne, United Kingdom
EDUCATION RESEARCH
285 TRENDS IN PRESCRIBING AND MONITORING OF FOLIC ACID SUPPLEMENTATION WITH LOW
DOSE METHOTREXATE (MTX) BY RHEUMATOLOGISTS IN THE UK
AM Abraham 1 , T Hlaing 1 , K Binymin 1,2 .
1
Rheumatology Department, Southport and Ormskirk NHS TRUST, Southport, United Kingdom; 2 Rheumatology,
Liverpool University, Liverpool, United Kingdom
286 STUDENT AND PATIENT EDUCATORS’ (PE) ATTITUDES TO PE LED UNDERGRADUATE
MUSCULOSKELETAL EXAMINATION TRAINING
N Raj 1 , LJ Badcock 1 , GA Brown 2 , CM Deighton 1 , SC O’Reilly 1 .
1
Rheumatology, Derbyshire Royal Infirmary, Derby, East Midlands, United Kingdom; 2 Postgraduate Dental and
Medical Education School of Community and Health Sciences, University of Nottingham, Nottingham, East
Midlands, United Kingdom
287 MUSCULOSKELETAL EXAMINATION ON THE MEDICAL ADMISSION UNIT – STILL BEING
OVERLOOKED!
RE Forgie 1 , AC Collins 1 , J Hamilton 1 , C Heycock 1 , C Kelly 1 , V Saravanan 1 .
1
Rheumatology, Queen Elizabeth Hospital, Gateshead, Tyne and Wear, United Kingdom
288 EDUCATIONAL NEEDS OF PATIENTS WITH OSTEOARTHRITIS
ME Ndosi 1 , J Hill 1 .
1
Academic and Clinical Unit of Musculoskeletal Nursing, University of Leeds, Leeds, West Yorkshire, United
Kingdom
289 INTERNET RESOURCES FOR PATIENTS WITH ANKYLOSING SPONDYLITIS
B Thompson, LJ Kay.
1
Department of Rheumatology, Freeman Hospital, Newcastle-upon-Tyne, United Kingdom
290 A MULTIMEDIA APPROACH TO TEACHING THE DESIGN AND ADAPTATION OF ENVIRONMENTS
FOR PEOPLE WITH ARTHRITIS
L Goodacre 1 , R Wilkinson 1 , K Zhang 2 , M Brown 2 , J Goodacre 1 .
1
Lancashire School of Health and Postgraduate Medicine, University of Central Lancashire, Preston, Lancs,
United Kingdom; 2 Department of Computing, University of Central Lancashire, Preston, Lancs, United Kingdom
77

291 CONFIDENCE IN PAEDIATRIC MUSCULOSKELETAL (pMSK) CLINICAL SKILLS AMONGST JUNIOR
DOCTORS IN ORTHOPAEDICS
S Jandial 1,2 , A Myers 2 , HE Foster 2 .
1
Department of Child Health, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom;
2
Musculoskeletal Research Group, University of Newcastle upon Tyne, Newcastle upon Tyne, United Kingdom
292 PATIENT EDUCATION IN RHEUMATOID ARTHRITIS: THE EFFECTIVENESS OF THE ARC BOOKLET AND
THE MIND MAP
DJ Walker 1 , A Adebajo 2 , PS Heslop 1 , J Hill 3 , J Firth 4 , P Bishop 5 , PS Helliwell 6 .
1
Musculoskeletal Unit, NUTH F NHS Trust, Freeman Hospital, Newcastle-upon-Tyne, United Kingdom; 2 Academic
Rheumatology Group, Division of Genomic Medicine Medical School, Sheffield, United Kingdom; 3 Academic &
Clinical Unit for Muskuloskeletal Nursing, Chapel Allerton Hospital, Leeds, United Kingdom; 4 Postgraduate Suite,
University of Leeds, Leeds, United Kingdom; 5 School of Education, University of Nottingham, Nottingham, United
Kingdom; 6 Academic Unit of Musculoskeletal & Rehab Medicine, Leeds NHS Trust, University of Leeds, Leeds,
United Kingdom
293 IMPROVEMENT IN SELF RATED KNOWLEDGE OF PAEDIATRIC MUSCULOSKELETAL MEDICINE IN
DELEGATES ATTENDING A PRIMARY CARE CONFERENCE
DJ Boyd 1 , EM Wise 1 , A Myers 2 , A Adebajo 3 , J Dickson 4 , HE Foster 2 .
1
Rheumatology Department, Freeman Hospital, Newcastle upon Tyne, United Kingdom; 2 Musculoskeletal Research
Group, Newcastle University, Newcastle upon Tyne, United Kingdom; 3 Accademic Rheumatology, Sheffield
University Medical School, Sheffield, United Kingdom; 4 Musculoskeletal Medicine, Redcar and Cleveland PCT,
Gisborough, United Kingdom
294 WHAT’S STOPPING EARLY RHEUMATOID ARTHRITIS REFERRALS?
EM Wise 1 , DA Coady 1 , DJ Walker 1 .
1
Department of Rheumatology, Freeman Hospital, Newcastle upon Tyne, Tyne & Wear, United Kingdom
295 USE OF THE REGIONAL EXAMINATION OF THE MUSCULOSKELETAL SYSTEM (REMS) HANDBOOK
AND DVD
B Thompson, LJ Kay, DJ Walker, DA Coady.
1
Department of Rheumatology, Freeman Hospital, Newcastle-upon-Tyne, United Kingdom
296 A QUALITATIVE ASSESSMENT OF THE ARC RA LITERATURE; BOOKLET AND MIND-MAP
SM Robinson 1 , NJ Marshal 1 , AM Smith 1 , PS Heslop 1 , DJ Walker 1 .
1
Musculoskeletal Unit, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom
297 COMPARING FOURTH YEAR MEDICAL STUDENTS USING PEER ASSISTED LEARNING TO A
SPECIALIST PHYSIOTHERAPIST TEACHING MUSCULOSKELETAL SCREENING
K Graham 1 , J Burke 1 , R Mathew 2 , M Field 1 .
1
Department of Medical Education, University of Glasgow, Glasgow, Scotland, United Kingdom; 2 Learning and
Teaching Centre, University of Glasgow, Glasgow, Scotland, United Kingdom
298 BARRIERS TO RESEARCH DURING RHEUMATOLOGY SPECIALIST TRAINING – A PILOT STUDY
SG Dubey 1 , J Lee 2 , JK Gaffney 1 .
1
Dept of Rheumatology, Norfolk and Norwich University Hospital, Norwich, Norfolk, United Kingdom; 2 Dept of
Rheumatology, Luton and Dunstable Hospital NHS Trust, Luton, United Kingdom
78

POSTER VIEWING 3 - FRIDAY
EPIDEMIOLOGY
299 ANTI-CCP ANTIBODES AT BASELINE ARE AN IMPORTANT PREDICTOR OF FUNCTIONAL
DISABILITY AT 10 YEARS IN PATIENTS WITH INFLAMMATORY POLYARTHRITIS
D Plant 1 , TM Farragher 1 , D Burn 2 , DPM Symmons 1 .
1
arc Epidemiology Unit, University of Manchester, Manchester, United Kingdom; 2 Norfolk Arthritis Register,
Norfolk & Norwich University Hospital, Norwich, United Kingdom
300 CHRONIC WIDESPREAD PAIN PREDICTS THE ONSET OF FREQUENTLY UNEXPLAINED SYNDROMES
– A PROSPECTIVE POPULATION STUDY
VR Aggarwal, GJ Macfarlane, J Mcbeth.
1
Arc Epidemiology Unit, University of Manchester, Manchester, United Kingdom; 2 Aberdeen Pain Research
Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom; 3 Arc Epidemiology Unit,
University of Manchester, Manchester, United Kingdom
301 HOW ACCURATE ARE DIAGNOSES FOR RHEUMATOID ARTHRITIS AND JUVENILE IDIOPATHIC
ARTHRITIS IN THE GENERAL PRACTICE RESEARCH DATABASE?
SL Thomas 1 , CJ Edwards 2 , L Smeeth 1 , C Cooper 3 , AJ Hall 1 .
1
Department of Epidemiology and Public Health, London School of Hygiene & Tropical Medicine, London, United
Kingdom; 2 Department of Rheumatology, Southampton General Hospital, Southampton, United Kingdom; 3 MRC
Epidemiology Resource Centre, University of Southampton, Southampton, United Kingdom
302 THE PRESENTATION OF NEW REGIONAL MUSCULOSKELETAL DISORDERS TO PRIMARY CARE
K Jordan 1 , P Croft 1 .
1
Primary Care Musculoskeletal Research Centre, Keele University, Newcastle, Staffs, United Kingdom
303 THE EPIDEMIOLOGY OF CHRONIC WIDESPREAD PAIN IN EUROPEAN MEN: EVIDENCE FROM THE
EUROPEAN MALE AGEING STUDY (EMAS)
GJ Macfarlane 1 , S Pye 2 , J Finn 3 , AJ Silman 2 , G Bartfai 4 , F Casanueva 5 , G Forti 6 , A Giwercman 7 , IT Huhtaniemi 8 ,
K Kula 9 , M Punab 10 , D Vanderschueren 11 , FCW Wu 3 .
1
Aberdeen Pain Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United
Kingdom; 2 Division of Epidemiology and Health Sciences (arc Epidemiology Unit), University of Manchester,
Manchester, United Kingdom; 3 Division of Cardiovascular and Endocrine Sciences, University of Manchester,
Manchester, United Kingdom; 4 Department of Obstetrics and Gynaecology, University of Szeged, Szeged,
Hungary; 5 University of Santiago de Compostela, Santiago de Compostela, Spain; 6 Endocrinology Unit, University
of Florence, Florence, Italy; 7 Fertility Centre, Malmo University Hospital, Lund University, Lund, Sweden;
8
Institute of Reproductive and Developmental Biology, Imperial College, University of London, London, United
Kingdom; 9 Department of Andrology and Reproductive Endocrinology, Institute of Endocrinology, Medical
University of Lodz, Lodz, Poland; 10 Clinics of Surgery, Tartu Univeristy Clinicum, Tartu, Estonia; 11 Division of
Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium
304 WORK-RELATED MUSCULOSKELETAL DISORDERS SEEN IN GENERAL PRACTICE (GP)
L Hussey, K Thorley, S Turner, R Parker, A Agius, R McNamee.
1
Centre for Occupational & Environmental Health, The University of Manchester, Manchester, Greater
Manchester, United Kingdom
79

305 ROAD TRAFFIC ACCIDENTS DO NOT PREDICT THE ONSET OF WIDESPREAD BODY PAIN
J McBeth 1 , B Nicholl 1 , GT Jones 2 , G Wynne-Jones 3 , NJ Wiles 4 .
1
Arthritis Research Campaign Epidemiology Unit, University of Manchester, Manchester, United Kingdom;
2
Aberdeen Research Collaboration (Epidemiology Group) Department of Public Health, University of Aberdeen,
Aberdeen, United Kingdom; 3 Primary Care Musculoskeletal Research Centre, Keele University, Keele, United
Kingdom; 4 Academic Unit of Psychiatry, Department of Community Based Medicine, University of Bristol, Bristol,
United Kingdom
306 SLEEP AND PAIN: RESTORATIVE SLEEP PREDICTS THE RESOLUTION OF CHRONIC WIDESPREAD
PAIN
KA Jones 1 , GJ Macfarlane 2 , BI Nicholl 1 , C Dickens 3 , R Morris 4 , D Ray 5 , J McBeth 1 .
1
Arthritis Research Campaign Epidemiology Unit, University of Manchester, Manchester, United Kingdom;
2
Aberdeen Pain Research Collaboration (Epidemiology Group), Department of Public Health, University of Aberdeen,
Aberdeen, United Kingdom; 3 Department of Psychiatry, University of Manchester, Manchester, United Kingdom;
4
School of Community Health Sciences, University of Nottingham, Nottingham, United Kingdom; 5 Endocrine
Sciences Research Group, University of Manchester, Manchester, United Kingdom
307 THE RELATIONSHIP BETWEEN SOCIOECONOMIC STATUS AND THE ONSET OF CHRONIC
WIDESPREAD PAIN IS EXPLAINED BY PSYCHOLOGICAL STATUS
BI Nicholl 1 , KA Jones 1 , GJ Macfarlane 2 , C Dickens 3 , RK Morriss 4 , D Ray 5 , J McBeth 1 .
1
Arthritis Research Campaign Epidemiology Unit, University of Manchester, Manchester, United Kingdom;
2
Aberdeen Pain Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom;
3
Department of Psychiatry, University of Manchester, Manchester, United Kingdom; 4 Division of Psychiatry,
University of Nottingham, Nottingham, United Kingdom; 5 Endocrine Sciences Research Group, University of
Manchester, Manchester, United Kingdom
308 WORKPLACE MONOTONY AND MUSCULOSKELETAL PAIN – UNDERSTANDING THE MECHANISMS
GT Jones 1 , F Blyth 1,2 , M Mikkelsson 3 , P Knekt 4 , A Aromaa 4 , M Heliovaara 4 , GJ Macfarlane 1 .
1
Aberdeen Pain Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom;
2
School of Public Health, University of Sydney, Sydney, Australia; 3 Department of Rehabilitation, The Rheumatism
Foundation Hospital, Heinola, Finland; 4 National Public Health Institute, Helsinki, Finland
309 DIET AND DISABILITY IN EARLY INFLAMMATORY POLYARTHRITIS
DJ Pattison 1 , M Lunt 2 , A Welch 3 , SA Bingham 4 , DPM Symmons 2 .
1
School of Health Professions, University of Plymouth, Plymouth, Devon, United Kingdom; 2 ARC Epidemiology Unit,
University of Manchester, Manchester, United Kingdom; 3 School of Clinical Medicine, University of Cambridge,
Cambridge, United Kingdom; 4 Dunn Human Nutrition Unit, Medical Research Council, Cambridge, United Kingdom
310 DIFFERENCES IN CARDIOVASCULAR RISK FACTOR PROFILES BETWEEN PATIENTS WITH AND
WITHOUT RHEUMATOID ARTHRITIS
SR Brady 1 , D Liew 1 , B deCourten 2 , CM Reid 1,2 .
1
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia;
2
Baker Heart Research Institute, Melbourne, Victoria, Australia
311 FUNCTIONAL AND CONCEPTUAL TRENDS AND DEVELOPMENTS IN MUSCULOSKELETAL,
OCCUPATIONAL DISEASE: MOSS DATA 2002-2005
A Slovak, M Carder, SM Turner, R McNamee, A Agius.
1
Centre for Occupational and Environmental Health, The University of Manchester, Manchester, England,
United Kingdom
80

312 HOW COMMON IS CHRONIC RENAL DISEASE IN PATIENTS ATTENDING RHEUMATOLOGY
OUTPATIENT CLINICS?
A Hill 1 , R Thomson 1 , JP Traynor 2 , G Roberts 3 , J Hunter 3 .
1
Medical School, University of Glasgow, Glasgow, United Kingdom; 2 Department of Renal Medicine, Western
Infirmary, Glasgow, United Kingdom; 3 Department of Rheumatology, Gartnavel General Hospital, Glasgow,
United Kingdom
SOFT TISSUE AND REGIONAL MUSCULOSKELETAL DISEASE, FIBROMYALGIA
313 SENSITIVITY TO CHANGE OF THE CARPAL TUNNEL SYNDROME GLOBAL SEVERITY SCORING
SYSTEM: A PROSPECTIVE STUDY
Y El Miedany 1 , S Ashour 2 , S Youssef 1 , A Mehanna 3 , M El Gaafary 4 .
1
Rheumatology and Rehabilitation, Ain Shams University, Cairo, Egypt; 2 Neurology, Ain Shams University, Cairo,
Egypt; 3 Radiology, Ain Shams University, Cairo, Egypt; 4 Community, Enviromental and Occupational Medicine,
Ain Shams University, Cairo, Egypt
314 CHRONIC LOW BACK PAIN IS ASSOCIATED WITH HIGH RATES OF ATTENDANCE IN PRIMARY AND
SECONDARY CARE AND CONSIDERABLE USE OF COMPLEMENTARY THERAPIES
K Walker-Bone 1 , IC Reading 2 , H Martin 2 , A Aihie Sayer 2 , C Cooper 2 , EM Dennison 2 .
1
Rheumatology, Brighton & Sussex Medical School, Brighton, East Sussex, United Kingdom; 2 Rheumatology,
MRC Epidemiology Resource Centre, Southampton, Hants, United Kingdom
315 DIFFERING PATTERNS OF PSYCHOLOGICAL MORBIDITY PREDATE CHRONIC LOW BACK PAIN AND
ARE A CONSEQUENCE OF IT
K Walker-Bone 1 , IC Reading 2 , A Aihie-Sayer 2 , H Martin 2 , C Cooper 2 , EM Dennison 2 .
1
Rheumatology, Brighton & Sussex Medical School, Brighton, East Sussex, United Kingdom; 2 MRC Epidemiology
Resource Centre, Southampton General Hospital, Southampton, Hants, United Kingdom
316 SLEEP DISTURBANCE AND ITS RELATIONSHIP TO CYTOKINES IN PATIENTS WITH FIBROMYALGIA
SYNDROME
MA Stanislavchuk 1 , SV Kolyadenko 1 .
1
Rheumatology, National Medical University, Vinnytsya, Ukraine
317 MAGNESIUM DEFICIENCY AND SLEEP-DISORDERS IN PATIENTS WITH FIBROMYALGIA
MA Stanislavchuk 1 , VM Khomenko 1 .
1
Rheumatology, National Medical University, Vinnytsya, Ukraine
318 RATIO IL-8/IL10 IN PATIENTS WITH FIBROMYALGIA AND SLEEP-DISORDERS
VG Bass 1 , SV Kolyadenko 2 , MA Stanislavchuk 2 .
1
Internal Medicine, Kalynivka Regional Hospital, Kalynivka, Vinnytsja, Ukraine; 2 Rheumatology, National Medical
University, Vinnytsja, Vinnytsja, Ukraine
319 CAN SIMPLE CLINICAL TESTS REPLACE ELECTROMYOGRAPHY IN DIAGNOSIS OF CARPAL
TUNNEL SYNDROME?
L Das 1 , AS Sayegh 1 , SO’N Daunt 1 .
1
Rheumatology, Colchester General Hospital, Essex Rivers NHS Trust, Essex, Essex, United Kingdom
320 DOES ULTRASOUND GUIDED INJECTION OF PLANTER FASCITIS RELIEVE SYMPTOMS?
S Williams 1 , S Banykidde 2 , R Grant 2 .
1
Rheumatology, Queens Hospital, Romford, Essex, United Kingdom; 2 Radiology, Queens Hospital, Romford,
Essex, United Kingdom
81

321 THE PAIN BURDEN OF PARTICIPANTS IN PRAGMATIC TRIALS FOR REGIONAL MUSCULOSKELETAL
CONDITIONS
J Barber, M Lewis, S Mottram, EM Hay.
1
Primary Care Musculoskeletal Research Centre, Keele University, Keele, Staffordshire, United Kingdom
322 VITAMIN D LEVELS SHOULD NOT BE INCLUDED IN THE ROUTINE LABORATORY TESTS FOR
SCREENING PATIENTS WITH FIBROMYALGIC SYMPTOMS
NG Shenker, H Tahir.
1
Department of Rheumatology, Whipps Cross University Hospital, Leytonstone, London, United Kingdom
323 THE RELIEF OF CHRONIC LOW BACK PAIN IMMEDIATELY AFTER ONE SESSION OF LOW LEVEL
LASER ACUPUNCTURE THERAPY: AN EVALUATION OF THE EFFECT OF PRAYER
DA Houssien.
1
Rheumatology, Dr Dhiya for Rheumatism, Jeddah, Saudi Arabia
324 CAN A QUESTIONNAIRE REPLACE NEUROPHYSIOLOGY IN THE DIAGNOSIS OF CARPAL TUNNEL
SYNDROME?
J Bruce 1 , PT Dawes 2 .
1
School of Medicine, Keele University, Keele, Staffordshire, United Kingdom; 2 Staffordshire Rheumatology Centre,
Haywood Hospital, High Lane, Burslem, Stoke on Trent, Staffordshire, United Kingdom
OSTEOPOROSIS AND METABOLIC BONE DISEASE
325 THE IMPACT OF VERTEBRAL FRAGILITY FRACTURES ON HEALTH RELATED QUALITY OF LIFE IN
PATIENTS WITH OSTEOPOROSIS
Y El Miedany 1 , A Gardienr 2 , M Toth 3 .
1
Rheumatology, Darent Valley Hospital, Dartford, Kent, United Kingdom; 2 Osteoporosis and Falls Clinical Nurse
Specialist, Darent Valley Hospital, Dartford, Kent, United Kingdom; 3 Geriatric Medicine, Darent Valley Hospital,
Dartford, Kent, United Kingdom
326 STEROID INDUCED OSTEOPOROSIS: DISCORDANCE IN BONE MASS MEASUREMENT AT
DIFFERENT SITES
Y El Miedany 1 , A Gardiner 2 , M Toth 3 .
1
Rheumatology Department, Darent Valley Hospital, Dartford, Kent, United Kingdom; 2 Osteoporosis and Falls
Clinical Nurse Specialist, Darent Valley Hospital, Dartford, Kent, United Kingdom; 3 Geriatric Medicine, Darent Valley
Hospital, Dartford, Kent, United Kingdom
327 AXIAL VS PERIPHERAL BONE MINERAL DENSITY CHANGES AFTER INITIATION OF ANDROGEN
DEPRIVATION THERAPY IN MEN WITH PROSTATE CANCER
Y El Miedany 1 , A Gardiner 2 , I Dickinson 3 , M Toth 4 .
1
Rheumatology Department, Darent Valley Hospital, Dartford, Kent, United Kingdom; 2 Osteoporosis and Falls
Clinical Nurse Specialist, Darent Valley Hospital, Dartford, Kent, United Kingdom; 3 Urology Department, Darent
Valley Hospital, Dartford, Kent, United Kingdom; 4 Geriatric Medicine, Darent Valley Hospital, Dartford, Kent,
United Kingdom
328 PRACTICALITY, TOLERABILITY AND EFFICACY OF BOLUS VITAMIN D2 AND D3 TREATMENT IN
PATIENTS WITH VITAMIN D INSUFFICIENCY
P Leventis, PDW Kiely.
1
Rheumatology, St George’s Healthcare NHS Trust, London, United Kingdom
82

329 OSTEOPOROSIS IS ASSOCIATED WITH GREATER DETERIORATION IN SF36 SCORES AMONG MEN
BUT NOT WOMEN: THE HERTFORDSHIRE COHORT STUDY
EM Dennison 1 , KA Jameson 1 , A Aihie Sayer 1 , HJ Martin 1 , C Cooper 1 .
1
MRC Epidemiology Resource Centre, Southampton University, Southampton, Hants, United Kingdom
330 A COMPARISON OF IVA WITH STANDARD RADIOGRAPHS TO DETECT VERTEBRAL FRACTURE
AM Scott-Russell 1 , EM Dennison 2 , L Jones 3 , CC Cooper 2 .
1
Rheumatology Department, North Hampshire Hospital, Basingstoke, Hampshire, United Kingdom; 2 Medical
Research Council Epidemiology Resource Centre, Medical Research Council Epidemiology Resource Centre,
Southampton, Hampshire, United Kingdom; 3 Osteoporosis Centre, Southampton General Hospital,
Southampton, Hampshire, United Kingdom
331 COMPARISON OF ROENTOGRAPHY AND SCINTIGRAPHY IN PATIENTS WITH PAGET’S DISEASE
OF BONE
A Soni 1 , RS Manhas 1 , DA Collins 1 , EJ Price 1 , L Williamson 1 .
1
Rheumatology Department, Great Western Hospital, Swindon, United Kingdom
332 GLUCOCORTICOID-INDUCED OSTEOPOROSIS: ARE PRACTISING HOSPITAL DOCTORS AWARE OF
THE GUIDELINES AND DO THEY FOLLOW THEM?
J Keegan, K Davies, KE Walker-Bone.
1
Clinical Medicine Division, Brighton and Sussex Medical School, Brighton, United Kingdom
333 PREVALENCE OF OSTEOPOROSIS AND MORPHOMETRIC FRACTURES IN PATIENTS WITH
ANKYLOSING SPONDYLITIS AT TERTARY CARE CENTER IN INDIA
U Kumar, A Bhardwaj, V Srinivas, R Handa, A Kumar, AC Amini.
1
All India Institute of Medical Sciences, New Delhi, India
334 AN INTEGRATED FRACTURE LIAISON SERVICE. EVALUATION OF OSTEOPOROSIS, FALLERS,
PREVIOUSLY UNDISCLOSED CONDITIONS AND PATTERNS OF SUBSEQUENT REFERRAL
GPR Clunie, S Stephenson, JA Brache.
1
Department of Rheumatology and Care of The Elderly, The Ipswich Hospital NHS Trust, Ipswich, Suffolk,
United Kingdom
335 BISPHOSPHONATE EXPOSURE PRIOR TO TERIPARATIDE FOR OSTEOPOROSIS: DOES IT MATTER
IN CLINICAL PRACTICE?
ET Middleton, SA Steel, MM Lynn, SM Doherty.
1
Centre for Metabolic Bone Disease, Hull Royal Infirmary, Hull, East Yorkshire, United Kingdom
336 CHANGES IN SERUM BONE MARKERS IN RELATIONSHIP TO CHANGES IN BONE MINERAL
DENSITY DURING BISPHOSPHONATE TREATMENT IN PRIMARY OSTEOPOROSIS
DJ Armstrong 1 , J Hanratty 2 , SM Coward 3 , M McQuilkin 2 , MB Finch 2 .
1
Rheumatology, University Hospital of North Durham, Durham, Co Durham, United Kingdom; 2 Rheumatology,
Musgrave Park Hospital, Belfast, Northern Ireland, United Kingdom; 3 Biochemistry, Musgrave Park Hospital,
Belfast, Northern Ireland, United Kingdom
337 ELIGIBILITY FOR PTH THERAPY: HOW COMMON MIGHT IT BE?
MM Moinuddin 1 , P Taylor 2 , G Pearson 2 , N Arden 1 , EM Dennison 1 .
1
MRC Epidemiology Resource Centre, University of Southampton, Southampton, Hampshire, United Kingdom;
2
Osteoporosis Centre, Medical Physics Department, Southampton University Hospitals NHS Trust,
Southampton, Hampshire, United Kingdom
83

338 WHAT DO PATIENTS THINK OF ZOLEDRONATE?
SM Linton, ARC Renault, J Wiles, GM Huws.
1
Rheumatology Department, Nevill Hall Hospital, Abergavenny, United Kingdom
339 TERMINOLOGY USED IN VERTEBRAL X-RAY REPORTS AND THEIR INFLUENCE ON INVESTIGATION
AND MANAGEMENT OF FRACTURE RISK
S Wishart 2 , L McGregor 1 , C Mitchell 1 , RA Munro 1 .
1
Rheumatology, Wishaw General Hospital, Wishaw, Lanarkshire, United Kingdom; 2 Care of the Elderly, Wishaw
General Hospital, Wishaw, Lanarkshire, United Kingdom
340 THE USE OF INTRAVENOUS PAMIDRONATE IN OSTEOPOROSIS
AA Ginawi 1 , SA Love 2 , JE Compston 2 , AJ Crisp 1 .
1
Department of Rheumatology and Metabolic Bone Diseases, Cambridge University Hospitals NHS Foundation
Trusts, Cambridge, United Kingdom; 2 Department of Metabolic Bone Diseases, Cambridge University Hospitals
NHS Foundation Trusts, Cambridge, United Kingdom
341 PREDICTORS OF MALE OSTEOPOROSIS IN 1243 MALES REFERRED TO A DISTRICT GENERAL BONE
DENSITOMETRY SERVICE
S Maikandanathan, C Greenbank, JP Halsey, M Bukhari.
1
Rheumatology, Royal Lancaster Infirmary, Lancaster, Lancashire, United Kingdom
342 VITAMIN D LEVELS AND BONE BIOCHEMISTRY – DO NOT ALWAYS CORRELATE
A Nijjar, A Jones, RG Palmer, AA Faizal, A Sinha.
1
Department of Rheumatology, Solihull Hospital, Solihull, West Midlands, United Kingdom; 2 Department of Clinical
Biochemistry, Birmingham Heartlands Hospital, Birmingham, West Midlands, United Kingdom
343 VERTEBRAL FRACTURE ASSESSMENT AT THE TIME OF DXA SCANNING IMPROVES IDENTIFICATION
OF PATIENTS IN NEED OF TREATMENT FOR OSTEOPOROSIS BASED ON NICE GUIDELINES
S Chavrimootoo 2 , B Whelan 2 , P Hodnett 3 , M O’Sullivan 2 , E Falvey 2 , M Daly 2 , S Harney 2 , F Shanahan 1 ,
M Maher 3 , MG Molloy 2 .
1
Department of Medicine, University College Cork, Cork, Ireland; 2 Department of Rheumatology, Cork University
Hospital, Cork, Ireland; 3 Department of Radiology, Cork University Hospital, Cork, Ireland
344 GLUCOCORTICOID INDUCED OSTEOPOROSIS – ARE WE FOLLOWING THE GUIDELINES?
RHEUMATOLOGY EXPERIENCE
DK Ray 1 , N Viner 2 .
1
Rheumatology, Derriford Hospital, Plymouth, Devon, United Kingdom; 2 Rheumatology, Torbay Hospital, Torquay,
Devon, United Kingdom
345 THE DETECTION OF VERTEBRAL FRACTURES BY RADIOLOGISTS AND CLINICIANS IS COMPARABLE
WHEN USING A DXA SCANNER TO PERFORM VERTEBRAL FRACTURE ASSESSMENT
S Chavrimootoo 2 , B Whelan 2 , P Hodnett 3 , M O’Sullivan 2 , E Falvey 2 , M Daly 2 , S Harney 2 , F Shanahan 1 ,
M Maher 3 , MG Molloy 2 .
1
Department of Medicine, University College Cork, Cork, Ireland; 2 Department of Rheumatology, Cork University
Hospital, Cork, Ireland; 3 Department of Radiology, Cork University Hospital, Cork, Ireland
84

346 INFLUENCE OF PHYSICAL ACTIVITY ON CALCANEAL QUANTITATIVE ULTRASOUND (QUS):
RESULTS FROM THE EUROPEAN MALE AGEING STUDY (EMAS)
SR Pye 1 , TW O’Neill 1 , S Boonen 2 , H Borghs 2 , D Vanderschueren 2 , JE Adams 3 , G Bartfai 4 , F Casneuva 5 , JD Finn 6 ,
G Forti 7 , A Giwerceman 8 , I Huhtaniemi 9 , K Kula 10 , M Punab 11 , AJ Silman 1 , FC Wu 6 .
1
arc Epidemiology Unit, The University of Manchester, Manchester, United Kingdom; 2 University of Leuven,
Leuven, Belgium; 3 Department of Imaging Science and Biomedical Engineering, The University of Manchester,
Manchester, United Kingdom; 4 University of Szeged, Szeged, Hungary; 5 University of Santiago de Compostela,
Santiago de Compostela, Spain; 6 Andrology Research Unit, The University of Manchester, Manchester, United
Kingdom; 7 The University of Florence, Florence, Italy; 8 Lund University, Malmo, Sweden; 9 University of Turku,
Turku, Finland; 10 University of Lodz, Lodz, Poland; 11 University of Tartu, Tartu, Estonia
347 CHILDHOOD FRACTURES DO NOT PREDICT FUTURE FRACTURES: RESULTS FROM THE EUROPEAN
PROSPECTIVE OSTEOPOROSIS STUDY (EPOS)
SR Pye 1 , JH Tobias 2 , AJ Silman 1 , J Reeve 3 , TW O’Neill 1 .
1
arc Epidemiology Unit, The University of Manchester, Manchester, United Kingdom; 2 Rheumatology Unit,
Bristol Royal Infirmary, Bristol, United Kingdom; 3 University Department of Medicine, Strangeways Research
Laboratory, Cambridge, United Kingdom
348 HOW CAN WE ASSESS OSTEOPOROSIS IN THE VERY ELDERLY? A VALIDATION STUDY OF
HEEL DXA
L Ottewell 1 , RM Francis 2,3 , D Rawlings 2 , A Farley 4 , F Birrell 2,3,4 .
1
Rheumatology, Sunderland Royal Hospital, Sunderland, United Kingdom; 2 Musculoskeletal Unit, Freeman
Hospital, Newcastle upon Tyne, United Kingdom; 3 School of Clinical Medical Sciences, Newcastle University,
Newcastle upon Tyne, United Kingdom; 4 Northumbria Healthcare NHS Trust, Northumberland, United Kingdom
349 THE SAFETY AND EFFICACY OF VERTEBROPLASTY USING CORTOSS CEMENT IN A NEWLY
ESTABLISHED VERTEBROPLASTY SERVICE
ET Middleton 1 , CJ Rajaraman 2 , D Taylor 3 , DP O’Brien 2 , SA Steel 1 , SM Doherty 1 .
1
Centre for Metabolic Bone Disease, Hull Royal Infirmary, Hull, East Yorkshire, United Kingdom; 2 Department of
Neurosurgery, HRI, Hull, United Kingdom; 3 Department of Radiology, HRI, Hull, United Kingdom
350 THE EFFECTS OF ZOLEDRONATE ON ILIAC BONE REMODELLING; A HISTOMORPHOMETRIC STUDY
IN STROKE PATIENTS
KES Poole 1 , EA Warburton 2 , N Loveridge 3 , J Reeve 3 .
1
Department of Rheumatology, University of Cambridge Department of Medicine, Cambridge, United Kingdom;
2
Department of Stroke Research, University of Cambridge Department of Medicine, Cambridge, United
Kingdom; 3 Division of Bone Research, University of Cambridge Department of Medicine, Cambridge, United
Kingdom
CASE REPORTS (II)
351 TREATMENT RESISTANT HLA-B27 ASSOCIATED JUVENILE IDIOPATHIC ARTHRITIS MIMICKING
SYSTEMIC JUVENILE ARTHRITIS: MANAGEMENT OF SECONDARY SYSTEMIC AMYLOIDOSIS
AND THE FAILURE OF ANTI-TNFα THERAPY
FA Borg 1 , HJ Lachmann 2 , MR Ehrenstein 1 .
1
Centre for Rheumatology, University College London Hospital, London, United Kingdom; 2 National Amyloidosis
Centre, Royal Free Hospital, London, United Kingdom
352 COMPLICATED PYREXIA
DJ Hazlewood 1 , RF Kilding 1 , M Akil 1 .
1
Rheumatology, Royal Hallamshire Hospital, Sheffield, S Yorkshire, United Kingdom
85

353 MID-SUMMER RAYNAUD’S BLUES
BG Chikura.
1
Rheumatology, Countess of Chester Hopsital, Chester, United Kingdom
354 WITHDRAWN
355 RHEUMATOID ARTHRITIS PATIENT PERCEIVED AS HAVING SIDE EFFECTS FROM DMARDS USED
FOUND TO BE HIV (+)
C Tranmer, E Roussou.
1
Rheumatology & Rehabilitation King George Hospital, Barking Havering and Redbridge Trust, Ilford, Essex,
United Kingdom
356 AN UNUSUAL CASE OF KNEE PAIN
TE Toms 1 , R Butler 1 , K Eardley 2 .
1
Rheumatology, Royal Shrewsbury Hospital, Shrewsbury, West Midlands, United Kingdom; 2 Nephrology, Royal
Shrewsbury Hospital, Shrewsbury, West Midlands, United Kingdom
357 PACHYMENINGITIS WITH KIKUCHI’S DISEASE AS A PRESENTING FEATURE OF SLE
NJ Gullick, DP D’Cruz.
1
The Louise Coote Lupus Unit, St Thomas’ Hospital, London, United Kingdom
358 EOSINOPHILIC FASCIITIS: A RARE CAUSE OF RAPIDLY PROGRESSIVE PAINLESS JOINT
CONTRACTURES IN A 13-YEAR-OLD BOY
EJ Thorncroft 1 , SW Smale 1 , JP Camilleri 1 .
1
Rheumatology, University Hospital of Wales, Cardiff, United Kingdom
359 ADULT-ONSET STILL’S DISEASE IN A PATIENT WITH RECENT HIV INFECTION
EC Lawson 1 , K Bond 1 , K Walker-Bone 2 , DR Churchill 1 .
1
Department of Genitourinary Medicine, Royal Sussex County Hospital, Brighton, United Kingdom;
2
Rheumatology, Brighton & Sussex Medical School, Brighton, East Sussex, United Kingdom
360 RAPIDLY PROGRESSIVE INTERSTITIAL LUNG DISEASE IN TWO PATIENTS WITH anti-Jo-1
NEGATIVE DERMATOMYOSITIS
SL Westlake 1 , SCM Richards 2 , ND Hopkinson 1 .
1
Rheumatology, Royal Bournemouth and Christchurch Hospitals, Bournemouth, Dorset, United Kingdom;
2
Rheumatology, Poole Hospital, Poole, Dorset, United Kingdom
361 UBIQUITOUS YET UNUSUAL: FIRST REPORTED CASE OF NATIVE JOINT SEPTIC ARTHRITIS DUE TO
STAPHYLOCOCCUS EPIDERMIDIS IN A PATIENT ON ANTI TNF
A Abhishek 1 , P Courtney 1 .
1
Department of Rheumatology, City Hospital Nottingham, Nottingham, United Kingdom
362 BUT IS IT REALLY AN INFLAMMATORY MYOPATHY?
KP Ng 1 , C Smith 2 , DA Isenberg 1 .
1
Centre for Rheumatology, University College London, London, United Kingdom; 2 Rheumatology Department,
Barnet Hospital, London, United Kingdom
363 TWO CASES OF STAPHLOCOCCUS AUREUS SEPTIC SACRO-ILIITIS
EMA McCausland 1 , NW Liggett 1 .
1
Department of Rheumatology, Craigavon Area Hospital, Craigavon, Northern Ireland, United Kingdom
86

364 AMYLOID MYOPATHY ASSOCIATED WITH MYELOMA: A REPORT OF TWO CASES
K Chaabo 1 , D Pyne 1 , IT Saeed 2 , AS Jawad 1 .
1
Rheumatology, THe Royal London Hospital, London, London, United Kingdom; 2 Histopathology, Queen’s
Hospital, Romford, Essex, United Kingdom
365 TB ARTHRITIS, TB MENINGITIS & STEROIDS
S Bawa 1 , J McNally 2 .
1
Rheumatology, Nuffield Orthopaedic Centre, Oxford, United Kingdom; 2 Rheumatology, Royal Berkshire Hospital,
Reading, United Kingdom
366 TRANSIENT REGIONAL OSTEOPOROSIS PRESENTING AS INFLAMMATORY ARTHRITIS OF THE
FOOT AND ANKLE
D Sreerangaiah 1 , T Maruthappu 1 , R Dega 2 , A Steuer 1 .
1
Rheumatology, Wexham Park Hospital, Slough, Berkshire, United Kingdom; 2 Orthopaedics, Wexham Park
Hospital, Slough, Berkshire, United Kingdom
367 TRANSIENT LOSS OF VISION AND SYSTEMIC LUPUS ERYTHEMATOSUS
A Lateef 1 , A Lim 1 .
1
Medicine, National University Hospital, Singapore, Singapore
368 AIRWAY OBSTRUCTION CAUSED BY INFLAMMATORY DISEASE: DIAGNOSIS WITH THE
FLOW-VOLUME LOOP
AL Pozo 1 , WJM Kinnear 1 , P Lanyon 2 .
1
General Medicine, Queen’s Medical Centre, Nottingham, United Kingdom; 2 Rheumatology, Queen’s Medical
Centre, Nottingham, United Kingdom
369 A CASE OF REACTIVE ARTHRITIS SECONDARY TO PARVOVIRUS B19 INFECTION COMPLICATED
BY AN ACUTE TRANSVERSE MYELITIS
SC Earl 1 , B Zhang 2 , LM Thomas 2 , JM Ledingham 2 .
1
Rheumatology, North Hampshire Hospital, Basingstoke, Hampshire, United Kingdom; 2 Rheumatology, Queen
Alexandra Hospital, Portsmouth, Hampshire, United Kingdom
370 INFERIOR OSTEOPHYTES IN SYMPTOMATIC CONDENSING OSTEITIS OF THE CLAVICLE
S Kallankara 1 , AJ Roberts 2 , SK Sibtain 1 , TJ Gillott 1 , TJ Tait 1 , DW James 1 .
1
Rheumatology, Diana Princess of Wales Hospital, Grimsby, North East Lincolnshire, United Kingdom;
2
Orthopaedics, Diana Princess of Wales Hospital, Grimsby, North East Lincolnshire, United Kingdom
371 UNUSUAL COMPRESSIVE NEUROPATHY SECONDARY TO RHEUMATOID ARTHRITIS
AS Malipeddi, G Kallarackal.
1
Department of Rheumatology, Kettering General Hospital, Kettering, Northamptonshire, United Kingdom
372 A CASE OF STAPHYLOCOCCUS WARNERI INFECTION PRESENTING WITH BACK PAIN IN AN
IMMUNOCOMPROMISED HOST
JB Galloway, M Bukhari.
1
Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom
373 PORTABLE PULSE OXIMETRY – A SIMPLE AND USEFUL OUTPATIENT SCREEN FOR LUNG DISEASE
M Lloyd 1 , T Ho 2 , S Burton 1 . 1 Rheumatology, Frimley Park Hospital, Frimley, Surrey, United Kingdom; 2 Thoracic
Medicine, Frimley Park Hospital, Frimley, Surrey, United Kingdom; 3 Rheumatology, Frimley Park Hospital, Frimley,
Surrey, United Kingdom
87

374 SIGNS OF CORTICAL REORGANISATION RESOLVE IN A PATIENT WITH COMPLEX REGIONAL PAIN
SYNDROME SUCCESSFULLY TREATED AS AN OUTPATIENT
NG Shenker.
1
Department of Rheumatology, Royal London Hospital (Mile End), London, United Kingdom
375 ACUTE PSEUDOGOUT OF THE NECK – “CROWNED DENS SYNDROME”
MA Lee 1 , S Kyle 2 .
1
Rheumatology, Musgrove Park Hospital, Taunton, Somerset, United Kingdom; 2 Rheumatology, Royal Devon &
Exeter Hospital, Exeter, Devon, United Kingdom
376 TRANSIENT OSTEOPOROSIS OF SPINE – A CASE REPORT
DK Ray 1 , N Viner 2 .
1
Rheumatology, Derriford Hospital, Plymouth, Devon, United Kingdom; 2 Rheumatology, Torbay Hospital,
Torquay, Devon, United Kingdom
377 ACUTE MOTOR AXONAL NEUROPATHY IN A CASE OF SLE
MK Piper, S Brown, E Korendowych, N Giffin, N McHugh.
1
Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, Avon, United Kingdom; 2 Rheumatology,
Royal National Hospital for Rheumatic Diseases, Bath, Avon, United Kingdom; 3 Rheumatology, Royal National
Hospital for Rheumatic Diseases, Bath, Avon, United Kingdom; 4 Neurology, Royal United Hospital, Bath, Avon,
United Kingdom; 5 Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, Avon, United Kingdom
378 DON’T FORGET THE FACET JOINT!
HRV Reddy, JK Dawson.
1
Rheumatology Department, St Helens Hospital, Merseyside, United Kingdom
379 A CASE OF EROSIVE ARTHROPATHY IN TUBULOINTERSTITIAL NEPHRITIS UVEITIS (TINU)
SYNDROME
P Mangat 1 , A Jawad 2 .
1
Rheumatology, Royal Free Hospital, London, United Kingdom; 2 Rheumatology, The Royal London Hospital,
London, United Kingdom
MISCELLANEOUS RHEUMATIC DISEASES
380 PREVALENCE AND DISCRIMINATING ABILITY OF ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY
AND RHEUMATOID FACTOR IN RECOGNIZING RHEUMATOID ARTHRITIS FROM NON-RHEUMATOID
ARTHRITIS MUSCULOSKELETAL DISEASES
B Heidari, AR Firouzjahi, Z Lotfi.
1
Department of Internal Medicine, Shaheed Beheshti Hospital, Babol University of Medical Sciences, Babol,
Mazandran, Islamic Republic of Iran; 2 Department of Pathology and Medical Laboratory, Shaheed Beheshti
Hospital, Babol University of Medical Sciences, Babol, Mazandran, Islamic Republic of Iran; 3 Department of
Internal Medicine, Shaheed Beheshti Hospital, Babol University of Medical Sciences, Babol, Mazandran, Islamic
Republic of Iran
88

381 AN AUDIT OF RECORDING CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH RHEUMATOID
ARTHRITIS AND SYSTEMIC LUPUS ERYTHEMATOSUS IN CENTRES IN EAST ANGLIA AND THE
SOUTH EAST
FC Hall 1 , J Teir 2 , G Koduri 3 , A Meadows 4 , C Molyneaux 1 , P Mosthaghi 5 , B Ramabhadram 5 , K Poole 1 , J Pradeep 6 ,
S Lane 6 , G Pountain 7 , DGI Scott 2 , NJ Sheehan 4 , M Stodell 5 , A Young 4 .
1
University of Cambridge Department of Clinical Medicine, Addenbrooke’s Hospital, Cambridge, United Kingdom;
2
Department of Rheumatology, Norfolk and Norwich University Hospital, Norwich, United Kingdom; 3 Department
of Rheumatology, St Alban’s Hemel NHS Trust, St Alban’s, United Kingdom; 4 Department of Rheumatology, The
Edith Cavell Hospital, Peterborough, United Kingdom; 5 Department of Rheumatology, Luton and Dunstable
Hospital, Luton, United Kingdom; 6 Department of Rheumatology, Ipswich Hospital, Ipswich, United Kingdom;
7
Department of Rheumatology, Hinchingbrooke Hospital, Huntingdon, United Kingdom
382 AN AUDIT OF THE MANAGEMENT OF SEPTIC ARTHRITIS IN ADULTS AT NORTH TYNESIDE
GENERAL HOSPITAL
CA Warren, ML Grove.
1
North Tyneside Hospital, North Shields, Tyne and Wear, United Kingdom
383 THE MANAGEMENT OF SEPTIC ARTHRITIS – A SURVEY
LD Hordon.
1
Rheumatology, Dewsbury and District Hospital, Dewsbury, West Yorkshire, United Kingdom
384 EPITHELOID ANGIOSARCOMA MASQUERADING AS POLYMYALGIA RHEUMATICA AND PRIMARY
SYSTEMIC VASCULITIS
RI Amarasena 1 , S Kamath 2 .
1
Rheumatology, University Hospital Birmingham (Selly Oak), Birmingham, United Kingdom; 2 Rheumatology,
Haywood Hospital, Stoke-on-Trent, Staffordshire, United Kingdom
385 CONNECTIVE TISSUE DISEASES CO-EXIST WITH HUMAN IMMUNODEFICIENCY VIRUS (HIV)
INFECTION: FIVE CASE REPORTS
EL Wall 1 , M Fisher 2 , G Dean 2 , Y Gilleece 2 , D Churchill 2 , K Walker-Bone 3 .
1
Rheumatology, Brighton & Sussex University Hospitals NHS Trust, Brighton, East Sussex, United Kingdom;
2
GU Medicine, Brighton & Sussex University Hospitals NHS Trust, Brighton, East Sussex, United Kingdom;
3
Rheumatology, Brighton & Sussex Medical School, Brighton, East Sussex, United Kingdom
386 EXPERIENCE WITH BEHCET’S SYNDROME AT A MIDLANDS DISTRICT HOSPITAL
S Arthanari, M Nisar.
1
Dept of Rheumatology, Queens Hospital Trust, Burton on Trent, Staffs, United Kingdom
387 ADULT POLYMYOSITIS AND DERMATOMYOSITIS DIAGNOSIS AND OUTCOME
HA Ali,O Naji, S Balakrishnan, K Naish.
1
Rheumatology, New Cross Hospital, Wolverhampton, West Midland, United Kingdom; 2 Rheumatology, New
Cross Hospital, Wolverhampton, West Midland, United Kingdom; 3 Rheumatology, New Cross Hospital,
Wolverhampton, West Midland, United Kingdom; 4 Rheumatology, New Cross Hospital, Wolverhampton, West
Midland, United Kingdom
388 CLINICAL FEATURES OF SEPTIC ARTHRITIS IN PATIENTS ADMITTED TO HOSPITAL IN
NOTTINGHAM 1997-2001
JC Nixon 1 , K Mortimer 2 , S Holden 2 , AC Jones 1 , VC Weston 2 .
1
Department of Rheumatology, Nottingham University Hospitals Trust, Nottingham, United Kingdom;
2
Department of Microbiology, Nottingham University Hospitals Trust, Nottingham, United Kingdom
89

389 IDENTIFICATION AND MODIFICATION OF CARDIOVASCULAR RISK FACTORS IN RHEUMATOID
ARTHRITIS – HOW ARE WE DOING?
LM Hawley 1 , CA Dunne 1 .
1
Rheumatology, Christchurch Hospital, Christchurch, Dorset, United Kingdom
BHPR – AUDIT/SERVICE DELIVERY
390 ADHERENCE TO COMMITTEE ON SAFETY OF MEDICINES GUIDELINES ON PRESCRIPTION AND
DISTRIBUTION OF METHOTREXATE TABLETS
CD Sarsfield Watson 1 , K Walker Bone 1 , KM Jordan 1 .
1
Rheumatology Department, Brighton and Sussex University Hospital, Brighton, Sussex, United Kingdom
391 ATTITUDES TO EXERCISE – A SURVEY AMONG PATIENTS WITH INFLAMMATORY ARTHRITIS
LM Hawley 1 , DR Sparks 2 .
1
Rheumatology, Christchurch Hospital, Christchurch, Dorset, United Kingdom; 2 Physiotherapy, Christchurch
Hospital, Christchurch, Dorset, United Kingdom
392 THE MONITORING OF METHOTREXATE IN A GENERAL PRACTICE
A Siddiqui, JG Jones.
1
Dept of Rheumatology, Ysbyty Gwynedd, North West Wales NHS Trust, Bangor, Gwynedd, United Kingdom
393 IS A PICTORIAL PATIENT INFORMATION LEAFLET USEFUL FOR PATIENTS TAKING LEFLUNOMIDE?
A Soni 1 , L Kerton 1 , RS Manhas 1 , DA Collins 1 , EJ Price 1 , L Williamson 1 .
1
Rheumatology Department, Great Western Hospital, Swindon, United Kingdom
394 EFFECT OF NURSE-LED RHEUMATOLOGY TELEPHONE CLINICS ON FOLLOW-UP APPOINTMENTS
B Rhys-Dillon 1 , TM Lawson 1 , S Siebert 1 .
1
Department of Rheumatology, Princess of Wales Hospital, Coity Road, Bridgend, United Kingdom
395 EVALUATION OF A RHEUMATOLOGY HELPLINE
G Scott 1 , Y Mcloughlan 1 , J Hayes 1 , PJ Storrs 1 , F McKenna 1 .
1
Rheumatic Diseases Unit, Trafford General Hospital, Manchester, United Kingdom
396 MANAGEMENT OF ACUTE SCIATICA IN A CLINICAL ASSESSMENT TRIAGE SERVICE (CATS) RUN BY
EXTENDED SCOPE PRACTIONERS (ESP’S)
E Dechow 1 , J Kidd 1 , SCM Richards 1 .
1
Rheumatology Department, Poole Hospital NHS Trust, Poole, Dorset, United Kingdom
397 THE VALUE OF PATIENT INVOLVEMENT IN ASSESSING INTERPERSONAL AND COMMUNICATION
SKILLS AT INTERVIEW
SC Morris 1 , J Bailey-Dering 2 , AJ Coulson 1 .
1
Rheumatology Department, Withybush General Hospital, Haverfordwest, Pembrokeshire, United Kingdom;
2
Patient Volunteer and Regional Co-ordinator, National Rheumatoid Arthritis Society, Pembrokeshire, West Wales,
United Kingdom
398 DMARD MONITORING – IS IT PATIENT CENTRED? A LINCOLNSHIRE EXPERIENCE
R Yazdani 1 , K Horton 1 , VV Kaushik 1 .
1
Rheumatology, Lincoln County Hospital, Lincoln, Lincolnshire, United Kingdom
90

399 DEFINING THE ROLE OF HEALTH PSYCHOLOGISTS IN RHEUMATOLOGY
ED Hale 1 , GJ Treharne 2,1 , SM Peacock 3,4 , S Bonas 4 , GD Kitas 1,5,2 .
1
Department of Rheumatology, Dudley Group of Hospitals NHS Trust, Dudley, West Midlands, United Kingdom;
2
School of Psychology, University of Birmingham, Birmingham, United Kingdom; 3 Department of Health
Sciences, University of Leicester, Leicester, United Kingdom; 4 Pain Clinic, Milton Keynes General NHS Trust,
Milton Keynes, United Kingdom; 5 Research Institute in Healthcare Science, University of Wolverhampton,
Wolverhampton, United Kingdom
400 ANKYLOSING SPONDYLITIS PATIENTS SATISFYING BSR CRITERIA FOR ANTI-TNF HAVE CHRONIC
ACTIVE DISEASE, AND SHOW MARKED AND SUSTAINED RESPONSE
K Gadsby 1 , C Deighton 1 .
1
Department of Rheumatology, Derbyshire Royal Infirmary, Derby, United Kingdom
401 ANXIETY AND DEPRESSION IS COMMON IN PATIENTS WITH RHEUMATOID ARTHRITIS
G Scott, Y McLoughlin, F McKenna.
1
Rheumatic Diseases Unit, Trafford General Hospital, Manchester, United Kingdom
402 A LOOK INTO THE USE OF ANTI-TNF THERAPY IN RHEUMATOID ARTHRITIS AT COLCHESTER
GENERAL HOSPITAL
T Walton 1 , G Jacob 2 , N Hassan 3 .
1
Department of Rheumatology, Colchester General Hospital, Colchester, Essex, United Kingdom; 2 Department of
Rheumatology, Colchester General Hospital, Colchester, Essex, United Kingdom; 3 Department of Rheumatology,
Colchester General Hospital, Colchester, Essex, United Kingdom
403 CAN YOU TELL ME WHAT YOUR DIAGNOSIS IS?
G Morgans, K Lewis, A Negi, N Amos, JP Camilleri.
1
Rheumatology, University Hospital of Wales, Cardiff, S. Glam, United Kingdom
404 EARLY RHEUMATOID ARTHRITIS NETWORK (ERAN) AUDIT USING THE ARTHRITIS AND
MUSCULO-SKELETAL ALLIANCE (ARMA) PATIENT TOOL FOR INFLAMMATORY ARTHRITIS
M Cox 1 , L Hawley 2 , J Hall 3 , D Wilson 4 , W Garwood 5 , C Mayes 5 .
1
Nuffield Orthopaedic Centre, Oxford, United Kingdom; 2 Royal Bournemouth & Christchurch NHS Foundation
Trust, Christchurch, United Kingdom; 3 Stoke Mandeville Hospital, Aylesbury, United Kingdom; 4 Kings Mill
Hospital, Mansfield, United Kingdom; 5 St Albans City Hospital, St Albans, on Behalf of ERAN, United Kingdom
405 DNA’D OR NOT DNA’D THAT WAS THE QUESTION!
G Morgan, K Lewis, A Stephenson, N Amos, JP Camilleri.
1
Rheumatology, University Hospital of Wales, Cardiff, S. Glam, United Kingdom
406 IS A SUPPLEMENTARY PRESCRIBER A USEFUL SUPPLEMENT TO THE RHEUMATOLOGY TEAM?
R Copeland 1 , F Birrell 1,2,3 .
1
Rheumatology, Northumbria Healthcare NHS Trust, Northumberland, United Kingdom; 2 School of Clinical
Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom; 3 Freeman Hospital,
Newcastle upon Tyne, United Kingdom
407 AN EVALUATION OF THE CONTENT AND METHOD OF DELIVERY OF A FOOTCARE PROGRAMME
FOR PEOPLE WITH INFLAMMATORY ARTHRITIS
RJ Field 1 , J Cable 1 , SA Dewson 1 , J Baynham 1 , E Hinwood 2 .
1
Podiatry (Rheumatology Services), Bournemouth & Poole PCT, Bournemouth, Dorset, United Kingdom; 2 Clinical
Audit Department, The Royal Bournemouth & Christchurch Hospitals NHS Foundation Trust, Bournemouth,
Dorset, United Kingdom
91

408 PATIENT SATISFACTION SURVEY WITH A LUPUS TELEPHONE HELPLINE
SF Sawyer, CJ Edwards.
1
Southampton Lupus Clinic, Department of Rheumatology, Southampton University Hospitals NHS Trust,
Southampton, Hampshire, United Kingdom
409 USING A MULTI-DISCIPLINARY PATHWAY TO OPTIMISE INPATIENT CARE FOR THOSE WITH
COMPLEX REGIONAL PAIN SYNDROME: A SUCCESSFUL EXPERIENCE FOR ALL
CS McCabe 1,2 , J Beresford-Smith 1 , H Cohen 1,2 , S Derham 1 , C Dyer 1 , K Johnson 1 , SE Mainwaring 1 , C Richards 1 ,
KJ Rodham 1,3 , DR Blake 1,2 .
1
Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, Banes, United Kingdom; 2 School for Health,
University of Bath, Bath, Banes, United Kingdom; 3 Department of Psychology, University of Bath, Bath, Banes,
United Kingdom
410 AUDIT INTO THE REFERRAL PATTERN AND MODE OF REFERRAL TO OCCUPATIONAL THERAPY
D Fletcher.
1
Rheumatology Day Centre, Bristol Royal Infirmary, Bristol, United Kingdom
411 ‘JOINT ACTION’ – EXPERIENCE OF THE FRIMLEY PARK ARTHRITIS NEWSLETTER
M Lloyd 1 , S Burton 1 , S Gilliland 1 , B Lawes 1 , U David 2 .
1
Rheumatology, Frimley Park Hospital, Frimley, Surrey, United Kingdom; 2 Audit, Frimley Park Hospital,
Frimley, Surrey, United Kingdom
412 TUBERCULOSIS SCREENING PRIOR TO COMMENCEMENT OF ANTI-TNF ALPHA THERAPY
MA Lee 1 .
1
Rheumatology, Musgrove Park Hospital, Taunton, Somerset, United Kingdom
413 AN AUDIT OF ORAL METHOTREXATE TREATMENT IN A DISTRICT GENERAL HOSPITAL SETTING.
HOW WELL DO WE MEET CURRENT RECOMMENDATIONS?
GP Hirsch, F Chilton, J Lennon, S Dunn, S Rigby.
1
Department of Rheumatology, Warwick Hospital, Warwick, Warwickshire, United Kingdom
414 RESTORING FUNCTION: A CLINICAL EVALUATION OF THERAPY GOALS AS PART OF THE BATH
COMPLEX REGIONAL PAIN SYNDROME SERVICE
JS Lewis 1,2 , J Beresford-Smith 1 , CS McCabe 1,3 , H Cohen 1,3 , C Dyer 1 , K Johnson 1 , C Richards 1 , DR Blake 1,3 .
1
The Bath Complex Regional Pain Syndrome Service, The Royal National Hospital for Rheumatic Diseases, Bath,
United Kingdom; 2 School for Health Professions and Rehabilitation Sciences, University of Southampton,
Southampton, Hampshire, United Kingdom; 3 School for Health, University of Bath, Bath, United Kingdom
415 CAN WE SUCCESSFULLY CREATE PRIMARY CARE OSTEOPOROSIS RISK REGISTERS?
W Baqir 1 , M Lavender 2 , F Birrell 1,3,4 .
1
Rheumatology, Northumbria Healthcare NHS Trust, Northumberland, United Kingdom; 2 Northumberland Care
Trust, Northumberland, United Kingdom; 3 School of Clinical Medical Sciences, Newcastle University, Newcastle
upon Tyne, United Kingdom; 4 Freeman Hospital, Newcastle upon Tyne, United Kingdom
416 WHO BEST MONITORS DMARDS?
K Longbottom 1,2 , F Birrell 1,2,3 , P Crook 1,3 .
1
Rheumatology, Northumbria Healthcare NHS Trust, Newcastle upon Tyne, Northumberland, United Kingdom;
2
School of Clinical Medical Sciences, Newcastle University, Newcastle upon Tyne, Tyne and Wear, United
Kingdom; 3 Rheumatology, Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, United Kingdom
92

BHPR - RESEARCH
417 A CLINICAL TRIAL OF SPECIALIST FOOTWEAR FOR PATIENTS WITH RHEUMATOID ARTHRITIS
AE Williams 1 , K Rome 2 , CJ Nester 1 .
1
Centre for Rehabilitation and Human Performance Research, University of Salford, Salford, Manchester, United
Kingdom; 2 Teesside Centre for Rehabilitation Sciences, University of Teesside, Middlesborough, Tees Valley,
United Kingdom
418 EMOTIONS AND BELIEFS UPON DIAGNOSIS OF RHEUMATOID ARTHRITIS
L Jenkins 1 , M Hehir 2 , M Carr 3 , S Radford 4 , B Davis 1 , S Hewlett 2 .
1
Rheumatology Unit, Bristol Royal Infirmary, Bristol, United Kingdom; 2 School of Nursing, University of the West
of England, Bristol, United Kingdom; 3 Rheumatology Unit, St Peter’s Hospital, Chertsey, United Kingdom;
4
Psychology Dept, University of Bristol, Bristol, United Kingdom
419 WHAT INSPIRES JUNIOR HEALTH PROFESSIONALS TO BECOME RHEUMATOLOGY SPECIALISTS? A
SURVEY QUESTIONNAIRE
AV O’Brien 1 , S Hewlett 2 , B Clarke 2 , A Hammond 3 , S Ryan 4 , L Kay 5 , C Almeida 6 .
1
School of Health and Rehabilitation, Keele University, Keele, United Kingdom; 2 School of Nursing, University of
the West of England, Bristol, United Kingdom; 3 School of Health Professionals, Brighton University, Brighton,
United Kingdom; 4 Rheumatology Dept, Haywood Hospital, Stoke on Trent, United Kingdom; 5 Musculoskeletal
Unit, Freeman Hospital, Newcastle upon Tyne, United Kingdom; 6 Academic Rheumatology, Bristol University,
Bristol, United Kingdom
420 STUDENTS’ EXPECTATIONS FROM STUDYING THE ARC GRADUATE CERTIFICATE RHEUMATOLOGY
PRACTICE
A Hammond.
1
School of Health Professions, University of Brighton, Eastbourne, Sussex, United Kingdom
421 A STUDY TO COMPARE THE PREVALENCE OF SUBJECTIVE SLEEP DISTURBANCE IN RHEUMATOID
ARTHRITIS PATIENTS COMPARED TO A CONTROL GROUP OF SUBJECTS WITHOUT ARTHRITIS
PJ Storrs, D Bushell, F McKenna.
1
Rheumatic Diseases Unit, Trafford General Hospital, Manchester, United Kingdom
422 OBSERVATIONS OF IN-SHOE PLANTAR PRESSURES IN PATIENTS WITH RHEUMATOID ARTHRITIS
CJ Bowen 1 , M Backhouse 1 , J Burridge 1 , NK Arden 2 .
1
School of Health Professions and Rehabilitation Sciences, University of Southampton, Southampton,
Hampshire, United Kingdom; 2 MRC Epidemiology Resource Centre, University of Southampton, Southampton,
Hampshire, United Kingdom
423 ILLNESS PERCEPTIONS, COPING AND OUTCOMES IN FIBROMYALGIA
A Hammond.
1
Rheumatology, Derbyshire Royal Infirmary, Derby, Derbyshire, United Kingdom
424 TO EXPLORE THE CONTROL PERCEPTIONS OF YOUNG ADULTS WITH RHEUMATIC DISEASES
C Brownsell 1 .
1
Rheumatology, St Helens & Knowsley NHS Trust, St Helens, Merseyside, United Kingdom
425 A SURVEY OF THE EDUCATIONAL AND CLINICAL DEVELOPMENT NEEDS OF RHEUMATOLOGY
ALLIED HEALTH PROFESSIONALS STUDYING THE ARC GRADUATE CERTIFICATE IN
RHEUMATOLOGY PRACTICE
A Hammond, SJ Ryan, arc AHP Working Party.
1
School of Health Professions, University of Brighton, Eastbourne, Sussex, United Kingdom
93

426 ASSESSMENT OF CLINICAL NURSE SPECIALISTS IN RHEUMATOLOGY UTILISING AN OBJECTIVE
STRUCTURED CLINICAL EXAMINATION (OSCE)
S Ryan 1 , K Stevenson 2 , AB Hassell 1 .
1
Staffordshire Rheumatology Centre, Haywood Hospital, Burslem, Stoke on Trent, United Kingdom; 2 Physiotherapy
Department, University Hospital of North Staffs NHS Trust, Stoke on Trent, United Kingdom
427 FEMALE PERCEPTIONS OF THE EFFECTS OF FIBROMYALGIA ON SEXUAL RELATIONSHIPS
S Ryan 1 , J Hill 2 , C Thwaites 1 , PT Dawes 1 .
1
Staffordshire Rheumatology Centre, Haywood Hospital, High Lane, Burslem, Stoke on Trent, United Kingdom;
2
Academic Unit for Musculoskeletal Disease, Chapel Allerton Hospital, Leeds, West Yorkshire, United Kingdom
428 EDUCATIONAL NEEDS IN PATIENTS WITH ANKYLOSING SPONDYLITIS VARY WITH DISEASE
DURATION
DA Pickles 1 , DJ Bryer 1 , J Hill 2 , A Redmond 1 .
1
Academic Unit of Musculo Skeletal Disease, Chapel Allerton Hospital, Leeds, West Yorkshire, United Kingdom;
2
Academic and Clinical Unit of Musculoskeletal Nursing, Chapel Allerton Hospital, Leeds, West Yorkshire, United
Kingdom
429 AN IN-DEPTH EXPLORATION OF THE SEXUAL RELATIONSHIPS OF PARTNERS OF PEOPLE WITH
RHEUMATOID ARTHRITIS
G Grundy 1 , L Goodacre 2 , RJ Moots 1 , A Riley 2 , J Goodacre 2 .
1
Academic Rheumatology Dept, Aintree University Hospitals Foundation Trust, Fazakerley, Liverpool, United
Kingdom; 2 Lancashire School of Health and Postgraduate Medicine, University of Central Lancashire, Preston,
Lancashire, United Kingdom
430 AN INVESTIGATION OF THE ASSOCIATIONS PATIENTS MAKE BETWEEN CHANGES IN DISEASE
STATUS AND THE IMPACT OF CHANGE ON THEIR PSYCHOLOGICAL HEALTH IN ANKYLOSING
SPONDYLITIS
J Martindale 1 , J Smith 2 , D Grennan 3 , L Goodacre 2 , J Goodacre 2 .
1
Physiotherapy Department, Ashton Wigan and Leigh PCT, Wigan, Lancashire, United Kingdom; 2 Lancashire School
of Health and Postgraduate Medicine, University of Central Lancashire, Preston, Lancashire, United Kingdom;
3
Rheumatology Department, Wrightington Wigan and Leigh NHS Trust, Wrightington, Lancashire, United Kingdom
431 EXPLORING ILLNESS PERCEPTIONS OF INFLAMMATORY ARTHRITIS BETWEEN ATTENDERS AND
NON-ATTENDERS OF A PATIENT EDUCATION GROUP
JA McDowell 1 , DH Rees 1 , RB Williams 1 , C Foy 2 , S Norton 3 , J Weinman 4 .
1
Rheumatology Department, Hereford Hospitals NHS Trust, Hereford, United Kingdom; 2 Gloucestershire R&D
Support Unit, Gloucestershire Royal Hospital, Gloucester, United Kingdom; 3 East of England RDSU, University of
Hertfordshire, Hatfield, United Kingdom; 4 Department of Psychology (at Guy’s Hospital), Institute of Psychiatry,
5th Floor Thomas Guy House, London Bridge, London, United Kingdom
432 DO WRIST SPLINTS IMPROVE GRIP STRENGTH IN PATIENTS WITH RHEUMATOID ARTHRITIS?
M Sibley 1 , ER Gilgeours, PD Kiely, PL Peterson.
1
Rheumatology Department, St George’s Hospital, Tooting, London, United Kingdom
433 IMPACT OF DAS 28 SCREENING ON CLINICAL INTERVENTION IN PATIENTS WITH ESTABLISHED
RHEUMATOID ARTHRITIS
T Gripton 1 , DA Walsh 1,2 .
1
Rheumatology, Sherwood Forest Hospital’s NHS Trust Kings Mill Hospital, Sutton-in-Ashfield, Nottinghamshire,
United Kingdom; 2 Academic Rheumatology, University of Nottingham Clinical Sciences Building, City Hospital,
Hucknall Road, Nottingham, United Kingdom
94

BSR 08 -11 May 2007
International Convention Centre, Birmingham
95

Exhibitor Details
Stand No
Company
1 Arthritis Care
2 NRAS
3 arc
4 MS Specialist Library
5 RCN
6 NASS
7 Raynauds and Scleroderma Association
8 BSSA
9 NOS
10 ERAN
11 CCAA
12 Marfan’s Association
13 ARMA
14 TRB Chemedica
15-16 Novartis
17 Eli Lilly
18 Napp Pharmaceuticals
19 Roche Pharmaceuticals
20 Roche Pharmaceuticals
21/39 Schering Plough
22 Kyphon Europe
23 Wisepress
24 Vertec Scientific
25 Bauerfeind
26 Smith & Nephew
Stand No
Company
27 DJ Orthopaedics
28 Siemens
29 Actelion
30 BSR Biologics Register (BSR BR)
& Rheumatology/OUP
31 BSR and BHPR
32 LCA Pharmaceuticals
33 BioMarin
34-35 Servier Laboratories
36 Medac
37 Esaote
38 Bristol Myers Squibb
40 The Alliance for Better Bone Health
41 Abbott
42 MSD
43 Encysive
44-45 Wyeth
46 Sanofi-Aventis
47 Dynamic Imaging
48-49 UCB Pharmaceuticals
50 Nycomed
51 Clinovia
52 4S Dawn Clinical Software
53/55 Pfizer
54 Willow Healthcare
4S Dawn Clinical Software (Stand 52)
Please come and see our new shared care web browser based software for tracking DMARD and Anti-TNF patients.
The system has also many clinic/patient management facilities that helps you improve productivity, safety and quality
of care. It also helps address the key targets in NHS Hospital Trusts and Primary Care Trusts.
Abbott (Stand 41)
Abbott is a global, broad-based health care company devoted to discovering new medicines, new technologies and
new ways to manage health. Abbott scientists, leaders in the field of immunological research, are applying innovative
monoclonal antibody technology to discover and develop novel therapies to treat diseases of the immune system.
Their success already includes the first fully-human monoclonal antibody for the treatment of rheumatoid arthritis,
psoriatic arthritis and ankylosing spondylitis.
Actelion Pharmaceuticals (Stand 29)
Actelion is an independent Swiss biopharmaceutical company discovering, developing and marketing drugs for high
unmet medical needs. The UK affiliate currently provides therapies for pulmonary arterial hypertension and metabolic
disorders.
The Alliance for Better Bone Health (Stand 40)
The Alliance for Better Bone Health was formed in May 1997 to promote bone health and disease awareness through
numerous activities to support physicians and patients around the globe. It is a collaboration between Procter & Gamble
Pharmaceuticals Limited and Sanofi-Aventis.
96

arc (stand 3)
The Arthritis Research Campaign (arc) is the fourth largest medical research charity in the UK. It funds research into
all forms of arthritis and related conditions, provides information for health professionals and the public (including more
than 90 booklets and leaflets for patients), and also funds a variety of fellowships and bursaries.
ARMA (Stand 13)
The Arthritis and Musculoskeletal Alliance (ARMA) brings together over 30 member organisations including support
groups, professional societies and research organisations. Visit our stand to find out how you can use the Standards
of Care and our local networks to share good practice and improve services in your area. Also find out more about
our members and policy developments in the musculoskeletal community.
Arthritis Care (Stand 1)
Arthritis Care is the UK’s largest organisation working with and for all people with arthritis.
We believe that by working in partnership with you, we can achieve better outcomes for people with arthritis.
If you’d like to hear more about some of our work, such as information prescriptions, Challenging Pain – our new
self management course, Involving Users as Experts training, please contact: Christine Edwards
Christinee@arthritiscare.org.uk
Bauerfeind Train® (Stand 25)
Whenever joint problems stop movement, Train® active supports help restore mobility.
Train® active supports offer anatomically knitted compression supports with viscoelastic inserts. Activity isn’t
restricted and actually the opposite occurs; Train active supports work with the body to exert a therapeutic effect.
The intermittent massage combined with the compression exerted by the specially knitted fabric helps stimulate
circulation, enhances metabolism thereby accelerating recovery.
BioMarin (Stand 33)
BioMarin is biopharmaceutical company that has researched and developed 2 approved enzyme replacement
therapies in the field of rare lysosomal storage disorders. Mucopolysaccharidosis I (MPS I) and MPS VI are both
very rare conditions, and the symptoms may often masquerade as other more common conditions, particularly for
the more attenuated cases. BioMarin would like to encourage Physicians in the Rheumatology field to consider MPS
as a possible cause where the diagnosis is uncertain, and given that there are now licensed treatments available.
Bristol Myers Squibb (Stand 38)
Bristol-Myers Squibb is a global pharmaceutical and related healthcare products company whose mission is to
extend and enhance human life. Bristol-Myers Squibb’s primary focus is on the medicines business involving
research, development, manufacturing and supply of high-quality medicines around the world.
Our commitment to R&D has resulted in the discovery and development of innovative medicines to fight
cardiovascular disease, HIV/AIDS, cancer and mental health disorders.
BHPR (Stand 31)
The BHPR was formed in 1985 to bring together health professionals whose major interests lay in the management
of people with rheumatic diseases. The aim of the BHPR is to encourage a multi-disciplinary approach to the
management of people with rheumatic diseases. To provide a forum through which health professionals can exchange
knowledge, skills and experience. To generate greater awareness of the contribution of health professionals.
BSR (Stand 31)
The British Society for Rheumatology (BSR) is a professional medical society with over 1400 members. We are
committed to advancing knowledge and practice in the field of rheumatology. Visit the BSR stand to find out more
about the society’s work and pick up other useful information including copies of BSR’s new draft clinical guidelines.
97

BSR Biologics Register (BSR BR) (Stand 30)
The British Society for Rheumatology Biologics Register (BSRBR) is a prospective observational cohort study of patients
receiving anti-TNFα therapy for rheumatic conditions in the UK. The BSRBR collect data on anti-TNFα patients on a
6-monthly basis (for at least five years) via the rheumatologist. The aim of this data collection is to monitor changes to
drug therapy, disease activity and the occurrence of adverse events. A comparison cohort of similar patients receiving
conventional therapy is being collected at the same time.
BSSA (Stand 8)
Sjögren’s Syndrome is an auto immune condition that causes dry eyes and dry mouth associated with arthritis and
fatigue. It is a common disorder, affecting 3-4% of adults in the UK, but it is under diagnosed and may go untreated.
The British Sjögren’s Syndrome Association supports patients and carers, educates the public and professionals and
raises funds for research into this disabling condition.
CCAA (Stand 11)
The Children’s Chronic Arthritis Association is the leading charity run by parents and professionals to provide help and
information for children with arthritis, their families and professionals involved in their care. We offer emotional and
practical support to maximise choices and opportunities and raise awareness of childhood arthritis in the community.
Clinovia (Stand 51)
Clinovia, a member of the Bupa group is Britain’s most experienced healthcare provider. Our Services cover acute,
complex and chronic medical treatments at home. We support the NHS by providing high quality, tailored home
healthcare services. Our partnership approach helps Trusts meet their patient targets and reduce waiting lists whilst
ensuring patients receive the clinical home care they need.
Clinovia Ltd
Scimitar Park, Roydon Road,
Harlow, Essex. CM19 5GU
Tel: 01279 456789 Fax: 01279 419900
E-mail: enquiries@clinovia.co.uk Website: www.clinovia.co.uk
DJ Orthopaedics (Stand 27)
DJO UK Ltd specialises in rehabilitation and regenerative products marketed under the DonJoy® and Aircast® brand
names. The DonJoy® range of products includes knee bracing to relieve the pain associated with unicompartmental
osteoarthritis. A wide range of knee braces is available to match the varying degrees of pain and instability.
The Aircast® products include pneumatic walkers and ankle bracing.
Tel: 0800 587 0857 www.djo.eu
Dynamic Imaging (Stand 47)
Dynamic Imaging designs, manufactures, and distributes a range of high resolution ultrasound scanners with the
busy Rheumatology Department in mind. In addition to our successful DIASUS system we have recently added a
NEW affordable High Resolution Colour Doppler Ultrasound Scanner the DC-6.
The DC-6 is an intuitive ergonomic system to use with a wealth of features like “i-Touch” one button automatic
image optimisation and “i-Station” a patient information management platform to optimise work flow.
Eli Lilly (Stand 17)
Eli Lilly and Company Limited is one of the world's largest research-based pharmaceutical companies, dedicated to
creating and delivering innovative pharmaceutical healthcare solutions that enable people to live longer, healthier and
more active lives. Our research and development efforts constantly strive to address the world’s growing unmet
medical needs in several different clinical areas. To assist in the therapeutic management of Osteoporosis, Lilly has two
products each catering for different patient needs. For information about either of our osteoporosis products or services,
please come and talk to us at the Lilly stand.
We look forward to meeting you.
98

Encysive (Stand 43)
Encysive Pharmaceuticals. headquartered in Houston, Texas, is a biopharmaceutical company engaged in the discovery,
development and commercialization of novel, synthetic, small molecule compounds to address unmet medical needs.
The product portfolio and pipeline focuses on compounds in the cardiovascular and anti-inflammatory disease arenas.
Currently Encysive is building a European Sales and Marketing organization as it launches its first product in Europe.
The European headquarters in based in Uxbridge, London.
ERAN (Stand 10)
Early Rheumatoid Arthritis Network (ERAN)
MISSION STATEMENT
“To establish and maintain collection of long-term clinical data in order to monitor management and outcomes of
patients with early RA as part of Good Clinical Practice and Clinical Governance issues”.
For further information about ERAN, please come and see Wendy or Cathy at Stand No 10.
Contact details: +44 (0)1494 720420 or wgarwood@phlexglobal.com
Esaote (Stand 37)
Visit the Esaote stand to discuss the exciting opportunities that the next generation of ultrasound and MRI scanners
can offer your Rheumatology practice. As well as the MyLab25 mobile scanner, showcasing at the stand will be
Esaote’s advanced MyLab70 ‘Gold’ platform. This system not only incorporates the latest technologies but also
18 MHz probes. Come and visit the Esaote team and be innovated.
Kyphon Europe (Stand 22)
Kyphon develops and markets medical devices designed to restore spinal function using minimally invasive therapies
including Balloon Kyphoplasty, a procedure to treat Vertebral Compression Fractures.
The technique is designed to reduce and stabilize the fracture in a controlled way, to correct vertebral body deformity,
to provide significant pain reduction and improve parameters contributing to Quality Of Life.
For more information, visit www.kyphon-eu.com
LCA Pharmaceuticals (Stand 32)
LCA Pharmaceutical develops and manufactures an osteoarthritis treatment of three injections. In a large clinical
study (3 349 patients), this treatment appeared to have a rapid and sustained efficacy, allowing reduction of
analgesics and NSAIDS and was well tolerated.
Another product with sodium hyaluronate is dedicated for hip osteoarthritis (single intraarticular injection 3.0mL).
Combination of high molecular weight and high concentration is essential for treatment’s efficiency.
Marfan Association UK (Stand 12)
Marfan syndrome is a life-threatening disorder of the connective tissue, affecting many body systems, but primarily
the Eyes, Skeleton, Heart and Lungs. Dislocation of hypermobile joints, skeletal malformations and extreme height
contribute to daily pain and patients need as much help as possible to achieve a reasonable quality of life. We work
closely with related disorders as The British Coalition of Heritable Disorders of Connective Tissue.
Medac (Stand 36)
Medac is delighted to be at the 2007 BSR Annual meeting in Birmingham. Medac is an innovative German
pharmaceutical company with a well established research-based reputation and experience in oncology, haematology,
fibrinolysis and autoimmune disease. We are staffed by a team of healthcare and industry professionals and are
proud to be specialists meeting your specialist needs. We look forward to meeting you at stand 36.
Musculoskeletal Specialist Library (Stand 4)
The Musculoskeletal Specialist Library was launched in November 2003 and is part of the NHS National Library for
Health. It has been created, maintained and updated by a team comprising representatives from all of the professional
groups involved in the care of those suffering from musculoskeletal disorders. The site is intended primarily to support
those working in healthcare delivery but is also open to the public.
99

MSD (Stand 42)
Merck Sharp & Dohme Limited is the UK subsidiary of one of the world’s leading research-based pharmaceutical
companies, Merck & Co., Inc., of Whitehouse St, NJ, USA. The company discovers, manufactures and markets a
broad range of innovative products and services to improve human health.
Napp Pharmaceuticals Limited (Stand 18)
Napp Pharmaceuticals Limited, a leader in pain control, has brought many pioneering products to the UK, including
the worlds first prolonged release opioid, the first biphasic release opioid tablet and the UK’s first twice-weekly and
seven-day analgesic matrix patches.
NASS (Stand 6)
NASS, founded in 1976, is the UK charity working for patients with ankylosing spondylitis. Our work includes running
over 100 local branches which meet for physiotherapy each week; providing support, advice and information to patients
and their families; organising regular symposia attended by clinicians, researchers and patients; supporting research both
financially and through our members’ involvement and working with AS patient groups throughout the world.
NOS (Stand 9)
The NOS is the UK’s only national charity offering support to people with, or at risk of, osteoporosis and their carers.
The NOS works to raise awareness of osteoporosis and bone health, and works with health professionals across a
wide range of disciplines. Visit us on stand 9 to find out about our range of services and publications and see
www.nos.org.uk for further information.
Novartis Pharmaceuticals (Stand 15-16)
Novartis is a company committed to the discovery and development of medicines in areas of unmet clinical need.
The therapeutic areas that Novartis works in include cardiovascular and metabolism, neuroscience, respiratory, arthritis,
bone, infectious diseases, transplantation and immunology and oncology. Our product pipeline is one of the strongest in
the pharmaceutical industry and in the UK alone we spend around £1 million per week on research and development.
NRAS (Stand 2)
The National Rheumatoid Arthritis Society (NRAS) is the only UK patient-led charity exclusively dedicated to helping the
nearly half a million people in Britain with rheumatoid arthritis as well as their families, carers and health professionals.
NRAS offers a website, helpline and volunteer network service and also campaigns to raise public and government
awareness of RA.
Helpline 0800 298 7650 www.rheumatoid.org.uk
Nycomed (Stand 50)
Nycomed UK Ltd is part of a major European focused organisation with a vision to be the preferred partner for European
healthcare professionals in our areas of expertise. Building on our current platform in osteoporosis, we invite you to visit
our exhibition stand to meet our team and discuss current treatment options in this important disease area.
Oxford University Press/Rheumatology (Stand 30)
Oxford University Press publishes some of most respected medical books and journals in the world including the Oxford
Textbook of Rheumatology and one of the leading international journals in the field, Rheumatology, which is published on
behalf of the British Society for Rheumatology. Visit our stand to discover more about our quality products, and to
pick up a free copy of the journal.
Pfizer (Stand 53/55)
Pfizer Inc, the world’s largest research-based pharmaceutical company, discovers, develops, manufactures and markets
prescription medicines in 11 therapeutic areas. Pfizer conducts more biomedical research than any other corporation,
and has 14,000 professionals working in six major R&D sites worldwide, including Sandwich in Kent. Pfizer’s research
investment in 2005 was more than $7.4 billion. In the UK, Pfizer Ltd has its UK business headquarters in Surrey and is
the major supplier of medicines to the NHS.
100

Raynauds and Scleroderma Association (Stand 7)
This year the Raynaud’s & Scleroderma Association is celebrating its Silver Jubilee. Visit Stand No 7 to see the
Scleroderma DVD for Health Professionals, DVD of Scleroderma Family Weekend and latest book for patients and
allied health professionals, ‘SCLERODERMA - The Inside Story’ Price £5.99.
Come along and collect your free Penguin beanie mascot by filling in a short questionnaire (only available while
stocks last!).
RCN RF (Stand 5)
The Royal College of Nursing Rheumatology Forum (RCNRF) works to support nurses and aims to improve care and
raise awareness for individuals with musculoskeletal conditions in all care settings. The committee work with other
patient and professional organisations to improve standards of care nationally and internationally. The RCNRF also
run and annual conference for practitioners. As a member of the umbrella organisation ARMA the committee also
take an active role in representing nurses on working parties and lobbying to improve standards of care –
www.rcn.org.uk.
Roche Pharmaceuticals (Stands 19 & 20)
Roche aims to improve people's health and quality of life with innovative products and services for the early
detection, prevention, diagnosis and treatment of disease. Part of one of the world’s leading healthcare groups,
Roche in the UK employs nearly 2,000 people in pharmaceuticals and diagnostics. Globally Roche is the leader in
diagnostics, and a major supplier of medicines for the treatment of cancer, transplantation, virology, bone and
rheumatology, obesity and renal anaemia. Find out more at www.rocheuk.com
Sanofi Aventis (Stand 46)
In the UK, sanofi-aventis, an affiliate of the global pharmaceutical company sanofi-aventis, is a dynamic,
rapidly growing organisation that is working to meet the needs of healthcare professionals and their patients.
Our portfolio of products closely match the priorities of the NHS and include cardiovascular disease, thrombosis,
metabolic disorders, central nervous system disorders, oncology, internal medicine and vaccines.
Our commitment to the UK is strong. Our UK R&D spend is £45 million alone.
At sanofi-aventis we are committed to researching, developing and bringing to market new and innovative
healthcare products so we can fulfil our mission. Because health matters.
Schering Plough (Stand 21/39)
Schering-Plough Ltd is one of the world’s leading pharmaceutical corporations. Schering-Plough Immunology invites
you to Stand 21/39 to find out more information about the treatment of rheumatoid arthritis, ankylosing spondylitis &
psoriatic arthritis, and to our Satellite Symposium on Wednesday morning. Schering-Plough would like to wish all the
BSR and BHPR delegates an enjoyable conference and look forward to meeting you.
Servier Laboratories Ltd (Stand 34-35)
Servier Laboratories Limited is the British Subsidiary of the Servier Research Group, a leading French based
organisation specialising in ethical pharmaceuticals. Servier is currently within the top 15 largest pharmaceutical
companies in the UK. Servier’s product portfolio in the UK focuses on the therapeutic areas of Cardiovascular
disease, Diabetes, Osteoporosis and soon Depression. Servier's R&D pipeline is extremely healthy having the
potential to submit one product for license every year for the next 8 to 10 years. Servier UK and the whole Servier
Research Group is set for dramatic growth over this period. www.servier.co.uk
Siemens Medical Solutions (Stand 28)
In line with Siemens reputation for innovation we will be showcasing the new Acuson X300 ultrasound system.
The X300 is an ultra-compact, performance-oriented system designed for clinical efficiency. With an operator-friendly
console that helps to reduce arm and hand movement, and its small, lightweight transducers, the X300 system takes
the pain and pressure out of routine scanning. See us at stand 28 for more details.
101

Smith and Nephew (Stand 26)
Durolane®‚: The Single Injection For Osteoarthritis
Smith & Nephew Orthopaedics Ltd, market Durolane, the first single injection intra-articular treatment for osteoarthritis
of the knee and hip. Durolane is manufactured in a unique process which is called NASHA (Non Animal Stabilised
Hyaluronic Acid). This dramatically increases the intra-articular residence time dispensing with the need for repeated
injections. Smith & Nephew Orthopaedics are exhibiting on stand 26.
TRB Chemedica (Stand 14)
Viscoseal enhances post arthroscopy recovery by replacing lost synovial fluid. Ostenil treats osteoarthritis in large joints.
Ostenil mini treats osteoarthritis in small joints such as the fingers, toes and shoulder. All TRB products are non animal
derived medical devices. Samples can be supplied at the stand.
UCB Pharmaceuticals (Stand 48-49)
UCB (www.ucb-group.com) is a global biopharmaceutical leader, specialised in severe diseases within the fields of
central nervous system disorders (including epilepsy), allergy/respiratory diseases, immune and inflammatory disorders
and oncology. Employing more then 8,300 people in 40 countries (June 2006 data), UCB achieved revenue of 2.3 billion
euro in 2005.
Vertec Scientific (Stand 24)
Vertec Scientific Ltd. Would like to welcome you to the BSR meeting. We are located at Booth 24 where we will be
demonstrating the latest in Osteoporosis Bone Density scanners from Hologic Inc. In addition we also have the worlds
only dedicated high field 1.0T MRI scanner, for extremities from ONI inc.
Willow Healthcare Services (Stand 54)
Willow Healthcare delivers homecare services to patients across the United Kingdom. These consist of the provision of
medication (including compounded products), ancillary items and medical equipment direct to patients’ homes together
with associated Nursing support.
Wisepress (Stand 23)
Wisepress is pleased to present a display titles selected especially for the BSR Annual Meeting 2007 from the
world’s leading publishing houses. All titles can be bought / ordered either at the congress, or via our website:
www.wisepress.com. We can also order you free sample copies of the journals on display and take subscription orders.
Whatever your book requirements, Wisepress are happy to help.
Wisepress Online Bookshop
The Old Lamp Works
25 High Path, Merton Abbey
London SW19 2JL
Tel: 020 8715 1812 Fax: 020 8715 1722
e-mail: bookshop@wisepress.com
Wyeth (Stand 44-45)
Wyeth is one of the world’s leading research-driven pharmaceutical companies with a major focus on developing
innovative new medicines to improve health and well being. Wyeth has a portfolio of products across a wide range of
treatment areas, including rheumatology, dermatology, infectious disease, transplantation, mental health, women’s
healthcare, gastro-intestinal disease, haemophilia, prostate cancer, and vaccination. Wyeth is committed to working in
partnership with the NHS to support its priorities for health, and to developing new medicines to bring benefits for
patients and those who care for them.
102

Abstract Reviewers
The BSR Heberden Committee was expanded substantially for the purposes of abstract assessment to
ensure that every abstract was peer reviewed, blind, by at least 4 reviewers. The Heberden Committee is
extremely grateful for the assistance of everyone that gave up their time to review abstracts, and
acknowledges them accordingly:
Dr Anne Barton
Dr Fraser Birrell
Dr Paul Bowness
Dr M Callaghan
Prof M Callan
Prof Tim Cawston
Prof Yuti Chernajovsky
Prof Ian Clark
Dr David Coady
Dr David Collins
Dr Adrian Crisp
Prof P Croft
Dr Chris Deighton
Dr Chris Denton, Heberden Committee
Dr Lisa Dunkley
Dr Krysia Dziedzic
Prof R Eastell
Dr Sally Edmonds, Heberden Committee
Dr Nicola Erb
Mrs Diana Finney
Prof Roger Francis
Dr Karl Gaffney
Prof J S H Gaston, Heberden Committee
Dr Ian Giles
Dr John Halsey
Prof Dorian Haskard, Heberden Committee
Dr Brian Hazleman
Dr Jackie Hill
Dr Charles Hutton
Dr John Ioannou, Heberden Committee
Prof John Isaacs, Heberden Committee
Dr Rachel Jeffery, Heberden Committee
Dr Andrew Keat
Dr George Kitas, Heberden Committee
Dr E Korendowych
Dr T Lawson
Dr Mark Lillicrap
Prof Alex MacGregor, Heberden Committee
Prof Peter Maddison
Dr Chris Main
Dr Candy McCabe
Dr Liza McCann
Mrs Jackie McDowell
Dr Kim Midwood
Dr A W Morgan
Prof Hideaki Nagase
Dr George Peat
Dr Malcolm Persey
Dr Clarissa Pilkington
Prof Constantino Pitzalis
Dr Frederique Ponchel
Dr E Price, Heberden Committee
Mrs Isabel Raiman
Dr Elizabeth Rankin
Dr K Raza
Dr Tony Redmond
Dr Sarah Ryan
Dr Clive Ryder, Heberden Committee
Dr David Sansom, Heberden Committee
Prof David L Scott
Dr Alan Steuer
Dr Malcolm Stodell
Dr Richard Stratton
Dr Nurhan Sutcliffe
Dr Deborah Symmons
Dr Alister Taggart
Dr Peter Taylor
Prof Patrick Venables
Dr Tonia Vincent
Dr Nick Viner
Dr T Vyse
Dr David Walsh
Dr Richard Watts, Heberden Committee
Dr Ross Wilkie, Heberden Committee
Dr Lyn Williamson
Dr Gerry Wilson
Dr R Wolman
Dr Laurence Wood
Dr J Woodburn
Dr Adam Young
Dr Steven Young Min
104