Emerging cytokines and cytokine signalling molecules as ...
Emerging cytokines and cytokine signalling molecules as ...
Emerging cytokines and cytokine signalling molecules as ...
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Anti-<strong>cytokine</strong> therapies developed for psori<strong>as</strong>is<br />
CT637<br />
HMGB1-RAGE interaction<br />
Generic name<br />
Cytokine Target<br />
Etanercept, Infliximab, Adalimumab TNF<br />
Ustekinumab<br />
Briakinumab<br />
------<br />
Secukinumab<br />
Brodalumab<br />
Ixekizumab<br />
CNTO1959<br />
SCH900222<br />
Fezakinumab (ILV-094)<br />
NN8226<br />
IL12/23 p40<br />
IL12/23 p40 (withdrawn)<br />
IL-17<br />
IL-17<br />
IL-17<br />
IL-23p19<br />
IL-23p19<br />
IL-22<br />
IL-20<br />
AMG 714<br />
IL-15<br />
ABX-IL8 IL-8 (modest results in ph<strong>as</strong>e 2,<br />
MEDI 545<br />
discontinued for psori<strong>as</strong>is)<br />
IFNalpha (ph<strong>as</strong>e 1 completed, no<br />
clinical activity in established dise<strong>as</strong>e)
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