Emerging cytokines and cytokine signalling molecules as ...
Emerging cytokines and cytokine signalling molecules as ...
Emerging cytokines and cytokine signalling molecules as ...
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Cytokine receptors signal directly by activating kin<strong>as</strong>es<br />
Cytokines that use type I <strong>and</strong> II <strong>cytokine</strong> receptors signal via the activation of<br />
receptor-<strong>as</strong>sociated Janus kin<strong>as</strong>es (Jaks)<br />
Approx. 60 which<br />
bind to type I/II R<br />
(IFNs, ILs, CSFs<br />
etc)<br />
Jaks are essential<br />
for signaling<br />
Quint<strong>as</strong>-Cardama, Nat Rev Drug Discovery 2011
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