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Genome wide association studies in inflammatory myopathy and

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Populations Studied<br />

Cases<br />

Controls<br />

Population<br />

Sample<br />

Size<br />

Adult DM<br />

Women<br />

(%)<br />

Juvenile DM<br />

Sample<br />

Size<br />

Women<br />

(%)<br />

Sample<br />

Size<br />

Women<br />

(%)<br />

No. of<br />

Successfully<br />

genotyped<br />

SNPs<br />

Covariates<br />

Genomic<br />

<strong>in</strong>flation<br />

factor (λ)<br />

Czech/<br />

Hungarian<br />

178 70.80% 23 78.30% 256 57.40% 242530<br />

Population<br />

Structure<br />

1.01<br />

Spanish 43 81.40% 4 50% 259 65.60% 242871<br />

Population<br />

Structure<br />

1.009<br />

Swedish/<br />

Dutch<br />

48 68.80% 4 75% 642 72.40% 242644<br />

Population<br />

Structure<br />

1.021<br />

UK 149 65.80% 159 70.40% 2415 47.80% 236039 None 1<br />

USA 287 76.00% 283 69.60% 1152 70.80% 237155<br />

Population<br />

Structure<br />

1.073<br />

Metaanalysis<br />

705 72.4% 473 70.2% 4724 58.2% 241502 None 1.043<br />

21

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