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Autologous Bone Marrow Transplantation - Blog Science Connections

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358 Burkitts Lymphoma Purging Assay<br />

have already stressed elsewhere in this book (see Favrot et al. "Comparative<br />

Efficiency of an lmmunomagnetic Purging Procedure and a Rabbit Complement<br />

Lysis for Eliminating Burkitt's Lymphoma Cells From <strong>Bone</strong> <strong>Marrow</strong>," and<br />

Combaret et al. "Eliminating Burkitt's Cells From Excess <strong>Bone</strong> <strong>Marrow</strong> With an<br />

lmmunomagnetic Purging Procedure"), clinical pilot studies that permit an<br />

accurate quantification of residual malignant cells before and after the<br />

procedure for each individual patient are needed before extensive multicenter<br />

studies may be started. Our assay is promising in this respect.<br />

ACKNOWLEDGMENTS<br />

This work was supported by a grant from the FNCLCC and by grant 6519<br />

from the ARC.<br />

We thank Dr. G. Janossy of the Royal Free Hospital in London for providing<br />

RFB 7<br />

and for giving advice helpful in preparing the manuscript.<br />

REFERENCES<br />

1. Philip 1, Philip T, Favrot MC, Vuillaume M, Fontaniere B, Chamard D, Lenoir GM. JNCI<br />

1984;73:835.<br />

2. Philip I, Favrot MC, Philip T. In <strong>Autologous</strong> <strong>Bone</strong> <strong>Marrow</strong> <strong>Transplantation</strong>: Proceedings of the<br />

First International Symposium, Dicke KA, Spitzer G, Zander AR, eds. The University of Texas<br />

M. D. Anderson Hospital and Tumor Institute at Houston, Houston, 1985:341.<br />

3. Philip I, Favrot MC, Philip T. J Immunol Methods (in press).<br />

4. Favrot MC, Philip I, Philip T, Portoukalian J, Dore JF. JNCI 1984;73:841.<br />

5. Favrot MC, Maritaz O, Suzuki T, Cooper M, Philip I, Philip T, Lenoir GM. Int J Cancer (in press).<br />

6. Favrot MC, Philip I, Philip T. In <strong>Autologous</strong> <strong>Bone</strong> <strong>Marrow</strong> <strong>Transplantation</strong>: Proceedings of the<br />

First International Symposium, Dicke KA, Spitzer G, Zander AR, eds. The University of Texas<br />

M. D. Anderson Hospital and Tumor Institute at Houston, Houston, 1985:389.<br />

7. Favrot MC, Philip 1, Maritaz O, Garcon N, Philip T. Rev Fr Transfus lmmunohematol<br />

1985:28:455.<br />

8. Favrot MC, Philip I, Philip T, Pinkerton R, Lebacq AM, Forster K, Adeline P, Dore JF. Br J Haematol<br />

1986:64:161.<br />

9. Bast RC, de Fabritiis P, Upton J, Gelber R, Maver C, Nadler L, Sallan S, Ritz J. Cancer Res<br />

1985:45:499.<br />

10. de Fabritiis P, Bregni M, Upton J, Greenberger J, Nadler L, Rothstein L, Korbling M, Ritz J,<br />

Bast RC. Blood 1985:5:1064.<br />

11. LeBien TW, Stepan DE, Bartholomew RM, Stong RC, Anderson JM. Blood 1985:65:945.<br />

12. Uckun FM, Ramakrishnan S, Haag D, Houston LL. Leukemia Res 1985;9:83.

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